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Key Documents

Amihai Citri

Contact Information

Academic Offices

Personal Information
Email citri@stanford.edu Tel (650) 498-6127

Professional Education

Doctor of Philosophy, Weizmann Institute Of Science (2006)

Faculty Advisor

Robert Malenka

Publications

Synaptic plasticity: multiple forms, functions, and mechanisms. Citri A, Malenka RC. Neuropsychopharmacology. 2008; 33 (1): 18-41
A module of negative feedback regulators defines growth factor signaling. Amit I, Citri A, Shay T, Lu Y, Katz M, Zhang F, Tarcic G, Siwak D, Lahad J, Jacob-Hirsch J, Amariglio N, Vaisman N, Segal E, Rechavi G, Alon U, Mills GB, Domany E, Yarden Y. Nat Genet. 2007; 39 (4): 503-12
EGF-ERBB signalling: towards the systems level. Citri A, Yarden Y. Nat Rev Mol Cell Biol. 2006; 7 (7): 505-16
Hsp90 recognizes a common surface on client kinases. Citri A, Harari D, Shohat G, Ramakrishnan P, Gan J, Lavi S, Eisenstein M, Kimchi A, Wallach D, Pietrokovski S, Yarden Y. J Biol Chem. 2006; 281 (20): 14361-9
The achilles heel of ErbB-2/HER2: regulation by the Hsp90 chaperone machine and potential for pharmacological intervention. Citri A, Kochupurakkal BS, Yarden Y. Cell Cycle. 2004; 3 (1): 51-60
Hsp90 restrains ErbB-2/HER2 signalling by limiting heterodimer formation. Citri A, Gan J, Mosesson Y, Vereb G, Szollosi J, Yarden Y. EMBO Rep. 2004; 5 (12): 1165-70
The deaf and the dumb: the biology of ErbB-2 and ErbB-3. Citri A, Skaria KB, Yarden Y. Exp Cell Res. 2003; 284 (1): 54-65
Drug-induced ubiquitylation and degradation of ErbB receptor tyrosine kinases: implications for cancer therapy. Citri A, Alroy I, Lavi S, Rubin C, Xu W, Grammatikakis N, Patterson C, Neckers L, Fry DW, Yarden Y. EMBO J. 2002; 21 (10): 2407-17
N-methyl-D-aspartate receptor- and metabotropic glutamate receptor-dependent long-term depression are differentially regulated by the ubiquitin-proteasome system. Citri A, Soler-Llavina G, Bhattacharyya S, Malenka RC. Eur J Neurosci. 2009; 30 (8): 1443-50
Defective ubiquitinylation of EGFR mutants of lung cancer confers prolonged signaling. Shtiegman K, Kochupurakkal BS, Zwang Y, Pines G, Starr A, Vexler A, Citri A, Katz M, Lavi S, Ben-Basat Y, Benjamin S, Corso S, Gan J, Yosef RB, Giordano S, Yarden Y. Oncogene. 2007; 26 (49): 6968-78
A reciprocal tensin-3-cten switch mediates EGF-driven mammary cell migration. Katz M, Amit I, Citri A, Shay T, Carvalho S, Lavi S, Milanezi F, Lyass L, Amariglio N, Jacob-Hirsch J, Ben-Chetrit N, Tarcic G, Lindzen M, Avraham R, Liao YC, Trusk P, Lyass A, Rechavi G, Spector NL, Lo SH, Schmitt F, Bacus SS, Yarden Y. Nat Cell Biol. 2007; 9 (8): 961-9
Hsp90 inhibitor 17-AAG reduces ErbB2 levels and inhibits proliferation of the trastuzumab resistant breast tumor cell line JIMT-1. Zsebik B, Citri A, Isola J, Yarden Y, Szöllosi J, Vereb G. Immunol Lett. 2006; 104 (1-2): 146-55
Hsp90 increases LIM kinase activity by promoting its homo-dimerization. Li R, Soosairajah J, Harari D, Citri A, Price J, Ng HL, Morton CJ, Parker MW, Yarden Y, Bernard O. FASEB J. 2006; 20 (8): 1218-20
Geldanamycins trigger a novel Ron degradative pathway, hampering oncogenic signaling. Germano S, Barberis D, Santoro MM, Penengo L, Citri A, Yarden Y, Gaudino G. J Biol Chem. 2006; 281 (31): 21710-9
Epigen, the last ligand of ErbB receptors, reveals intricate relationships between affinity and mitogenicity. Kochupurakkal BS, Harari D, Di-Segni A, Maik-Rachline G, Lyass L, Gur G, Kerber G, Citri A, Lavi S, Eilam R, Chalifa-Caspi V, Eshhar Z, Pikarsky E, Pinkas-Kramarski R, Bacus SS, Yarden Y. J Biol Chem. 2005; 280 (9): 8503-12
Suppressors of cytokine signaling 4 and 5 regulate epidermal growth factor receptor signaling. Kario E, Marmor MD, Adamsky K, Citri A, Amit I, Amariglio N, Rechavi G, Yarden Y. J Biol Chem. 2005; 280 (8): 7038-48
LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation. Gur G, Rubin C, Katz M, Amit I, Citri A, Nilsson J, Amariglio N, Henriksson R, Rechavi G, Hedman H, Wides R, Yarden Y. EMBO J. 2004; 23 (16): 3270-81
Tal, a Tsg101-specific E3 ubiquitin ligase, regulates receptor endocytosis and retrovirus budding. Amit I, Yakir L, Katz M, Zwang Y, Marmor MD, Citri A, Shtiegman K, Alroy I, Tuvia S, Reiss Y, Roubini E, Cohen M, Wides R, Bacharach E, Schubert U, Yarden Y. Genes Dev. 2004; 18 (14): 1737-52
Polar expression of ErbB-2/HER2 in epithelia. Bimodal regulation by Lin-7. Shelly M, Mosesson Y, Citri A, Lavi S, Zwang Y, Melamed-Book N, Aroeti B, Yarden Y. Dev Cell. 2003; 5 (3): 475-86