Claude M. Nagamine

Professional Education

• D.V.M., University of Tennessee Veterinary Medicine (2004)
• Ph.D., University of California, Davis Ecology (1979)
• M.A., University of California, Davis Zoology (1975)
• B.S., University of Hawaii, Manoa Biology (1973)

Research Interests

Molecular genetics of mammalian sex determination and sexual differentiation, effects of Helicobacter hepaticus, a mouse bacterial pathogen, on colon cancer models, small animal disease models.

Publications

• Helicobacter hepaticus promotes azoxymethane-initiated colon tumorigenesis in BALB/cJ-IL10-deficient mice. Nagamine CM,  Rogers AB, Fox JG, Schauer DB.  Int J Cancer.  2008; 122 832-838
• Acute paraplegia in a young adult Long-Evans rat resulting from T-cell lymphoma. Nagamine CM,  Jackson C, Beck KA, Marini RP, Fox JG, Nambiar PR.  Contemp Topics Lab Anim Sci.  2005; 44 53-56
• Proliferative pododermatitis (canker) with intralesional spirochetes in three horses. Nagamine CM,  Castro F, Buchanan B, Schumacher J, Craig L..  J Vet Diagn Invest.  2005; 17 269-271
• Sex Reversal Caused by Mus musculus domesticus Y Chromosomes Linked to Variant Expression of the Testis-Determining Gene Sry Nagamine CM,  Morohashi K, Carlisle C, Chang D.  Dev. Biol..  1999; 216 182-194
• Ovotestes in B6-XXSxr sex reversed mice. Nagamine CM,  Capehart J., Carlisle C, Chang D.  Dev. Biol..  1998; 196 24-32
• Zfy2/1 fusion gene fails to replicate Zfy1 expression pattern in fetal gonads. Nagamine CM,  Carlisle C.  Genomics.  1997; 43 397-398
• The dominant white spotting oncogene allele Kit(W-42J) exacerbates XY(DOM) sex reversal. Nagamine CM,  Carlisle C.  Development.  1996; 123 3597-3605
• Absence of correlation between Sry polymorphisms and XY sex reversal caused by M. m. domesticus Y Chromosome. Carlisle C,  Winking H, Weichenhan D, Nagamine CM.  Genomics.  1996; 33 32-45
• The testis-determining gene, SRY, exists in multiple copies in Old World rodents. Nagamine CM,  Genetical Research.  1994; 64 151-159
• Distribution of the molossinus allele of Sry, the testis-determining gene, in wild mice. Nagamine CM,  Shiroishi T, Miyashita N, Tsuchiya K, Ikeda H, Takao N, Wu X-L, Jin M-L, Wang F-S, Kryukov AP, Akbar.  Molecular Biology and Evolution.  1994; 11 864-874
• Polymorphism of a CAG trinucleotide repeat within Sry correlates with B6.YDom sex reversal. Coward P,  Nagai K, Chen D, Thomas HD, Nagamine CM, Lau Y-FC.  Nature Genetics.  1994; 6 245-250
• The musculus-type Y chromosome of the laboratory mouse is of Asian origin. Nagamine CM,  Nishioka Y, Moriwaki K, Boursot P, Bonhomme F, Lau Y-FC.  Mammalian Genome.  1992; 3 84-91
• The two candidate testis-determining Y genes (Zfy-1, Zfy-2) are differentially expressed in fetal and adult mouse tissues. Nagamine CM,  Chan K, Hake LE, Lau Y-FC.  Genes Develop.  1990; 4 63-74
• Hst-3: an X-linked hybrid sterility gene. Guénet J-L,  Nagamine CM, Simon-Chazottes D, Montagutelli X, Bonhomme F.  Genetical Research.  1990; 56 163-165
• Development and fertility of ovaries in the B6.YDom sex-reversed female mouse. Taketo-Hosotani T,  Nishioka Y, Nagamine CM, Villalpando I, Merchant-Larios H.  Development.  1989; 107 95-105
• A PCR artifact: generation of heteroduplexes. Nagamine CM,  Chan K, Lau Y-FC.  Am J Hum Genet.  1989; 45 337-339
• Chromosome mapping and expression of a putative testis-determining gene in mouse. Nagamine CM,  Chan K, Kozak CA, Lau Y-F.  Science.  1989; 243 80-83
• Studies on the genetics of tda-1 XY sex reversal. Nagamine CM,  Taketo T, Koo GC.  Differentiation.  1987; 33 223-231
• The use of specific DNA probes to analyze the Sxr mutation in the mouse. Bishop CE,  Roberts C, Michot J-L, Nagamine CM, Winking H, Guénet J-L, Weith A.  Development.  1987; 101 (S): 165-167
• Linkage of the murine steroid sulfatase locus, Sts, to sex reversal, Sxr: a genetic and molecular analysis. Nagamine CM,  Michot J-L, Roberts C, Guénet J-L, Bishop CE.  Nucl Acid Res.  1987; 15 9227-9238
• Morphological development of the gonad in tda-1 XY sex reversal. Nagamine CM,  Taketo T, Koo GC.  Differentiation.  1987; 33 214-222
• Masculinization of female crayfish, Procambarus clarki (Girard), by androgenic gland implantation. Nagamine, CM,  Knight AW.  Int J Invert Reprod Devel.  1987; 11 77-87
• Induction of female breeding characteristics by ovarian tissue implants in androgenic gland ablated male freshwater prawns Macrobrachium rosenbergii (de Man)(Decapoda, Palaemonidae). Nagamine CM,  Knight AW.  Int J Invert Reprod Devel.  1987; 11 225-234
• A radiobinding assay for H-Y antigen using monoclonal antibodies. Nagamine C,  Reidy J, Koo GC.  Transplantation.  1984; 37 13-17
• H-Y antigen in XO mice. Koo G,  Reidy J, Nagamine CM.  Immunogenetics.  1983; 18 37-44
• Effects of androgenic gland ablation on the male primary and secondary sexual characteristics in the Malaysian prawn, Macrobrachium rosenbergii (de Man), with the first evidence of induced feminization in a nonhermaphroditic decapod. Nagamine C,  Knight A, Maggenti A , Paxman G.  Gen Comp Endocrinol.  1980; 41 423-441
• Masculinization of female Macrobrachium rosenbergii (de Man)(Decapoda, Palaemonidae) by androgenic gland implantation. Nagamine C,  Knight A, Maggenti A, Paxman G.  Gen Comp Endocrinol.  1980; 41 442-457
• The development, maturation, and function of the sexually dimorphic characteristics of the Malaysian prawn, Macrobrachium rosenbergii (de Man)(Decapoda, Palaemonidae). Nagamine C,  Knight AW.  Crustaceana.  1980; 39 141-152