John MacKenzie

Clinical Focus

• Diagnostic Radiology

Administrative Appointments

• Chief of Pediatric Musculoskeletal Imaging, Lucile Packard Children's Hospital , (2007– present )

Honors and Awards

• Fellow Research Trainee Prize, Radiology Society of North America (2007)
• Resident Research Trainee Prize, Radiology Society of North America (2004)
• Alpha Omega Alpha, Medical Honor Society (2000)
• Firestone Medal for Excellence in Biological Research, Stanford University (1995)

Professional Education

• Board Certification: Diagnostic Radiology, American Board of Radiology (2005)
• The Children's Hospital of Philadelphia (2007) PA
• Brigham and Women's Hospital, Harvard Medical School (2005) MA
• Board Certification: Pediatric Radiology, American Board of Radiology (2008)
• Fellow, Hosp. of the U. of Penn. Musculoskeletal & Body MRI (2006)
• Fellow, Children’s Hosp. of Philadelphia Pediatric Radiology (2007)
• Resident, Brigham and Women’s Hosp. Radiology (ABR Holman Research Pathway) (2005)
• Intern, Hosp. of the U. of Penn. Medicine (2001)
• Albert Einstein College of Medicine (2000) NY
• MS, Stanford University Biological Science (co-term) (1995)
• BS, Stanford University Computer Sci. & Biological Sci. (1995)
• Hospital of the University of Pennsylvania (2006) PA
• Hospital of the University of Pennsylvania (2001) PA

Graduate & Fellowship Program Affiliations

• Radiology

Research Interests

My work focuses on molecular imaging for the detection and treatment monitoring of musculoskeletal disease. Currently, we study novel carbon-based molecular probes for imaging inflammatory arthritis (rheumatoid and juvenile idiopathic arthritis) using high-field MRI.

Publications

• Imaging Rheumatoid Arthritis Mackenzie JD,  Karasick D.  Imaging of Arthritis and Metabolic Bone Disease.  2009;
• Advances in pediatric MR imaging. MacKenzie JD,  Vasanawala SS.  Magn Reson Imaging Clin N Am.  2008; 16 (3): 385-402, v
• Diffusion-weighted and diffusion tensor imaging for pediatric musculoskeletal disorders. MacKenzie JD,  Gonzalez L, Hernandez A, Ruppert K, Jaramillo D.  Pediatr Radiol.  2007; 37 (8): 781-8
• Reduced-dose CT: effect on reader evaluation in detection of pulmonary embolism. MacKenzie JD,  Nazario-Larrieu J, Cai T, Ledbetter MS, Duran-Mendicuti MA, Judy PF, Rybicki FJ.  AJR Am J Roentgenol.  2007; 189 (6): 1371-9
• Brain atrophy in mild or moderate traumatic brain injury: a longitudinal quantitative analysis. MacKenzie JD,  Siddiqi F, Babb JS, Bagley LJ, Mannon LJ, Sinson GP, Grossman RI.  AJNR Am J Neuroradiol.  2002; 23 (9): 1509-15
• Predominant VH genes expressed in innate antibodies are associated with distinctive antigen-binding sites. Seidl KJ,  Wilshire JA, MacKenzie JD, Kantor AB, Herzenberg LA, Herzenberg LA.  Proc Natl Acad Sci U S A.  1999; 96 (5): 2262-7
• Frequent occurrence of identical heavy and light chain Ig rearrangements. Seidl KJ,  MacKenzie JD, Wang D, Kantor AB, Kabat EA, Herzenberg LA, Herzenberg LA.  Int Immunol.  1997; 9 (5): 689-702
• Infarction and Osteonecrosis Dalinka M,  MacKenzie JD.  Imaging of Arthritis and Metabolic Bone Disease.  2009;
• MR arthrography made simple: indications and techniques. MacKenzie JD,  Pediatr Radiol.  2008; 38 Suppl 2 S240-2
• MRI of HAGL lesions: four arthroscopically confirmed cases of false-positive diagnosis. Melvin JS,  Mackenzie JD, Nacke E, Sennett BJ, Wells L.  AJR Am J Roentgenol.  2008; 191 (3): 730-4
• Lowering the thyroid dose in screening examinations of the cervical spine. Shu KM,  MacKenzie JD, Smith JB, Blinder EM, Bourgeois LM, Ledbetter S, Castronovo FP, Judy PF, Rybicki F.  Emerg Radiol.  2006; 12 (3): 133-6
• Imaging features of crystal-induced arthropathy. Choi MH,  MacKenzie JD, Dalinka MK.  Rheum Dis Clin North Am.  2006; 32 (2): 427-46, viii
• An ovary with a twist: a case of interesting sonographic findings of ovarian torsion. Villalba ML,  Huynh B, So M, Mackenzie JD, Ledbetter S, Rybicki F.  J Emerg Med.  2005; 29 (4): 443-6
• Atlantoaxial instability associated with an orthotopic os odontoideum: a multimodality imaging assessment. Vargas TM,  Rybicki FJ, Ledbetter SM, MacKenzie JD.  Emerg Radiol.  2005; 11 (4): 223-5
• Quantification of clinical consultations in academic emergency radiology. Viscomi S,  Shu KM, Blinder EM, MacKenzie JD, Ledbetter S, Rybicki FJ.  Acad Radiol.  2004; 11 (11): 1294-7
• Uterine rupture with peritonitis in a nongravid uterus eight weeks after cesarean section. Blinder E,  MacKenzie JD, Cranmer HH, Ledbetter S, Rybicki F.  Emerg Radiol.  2003; 10 (1): 57-9
• The World Wide Web: redefining medical education. MacKenzie JD,  Greenes RA.  JAMA.  1997; 278 (21): 1785-6
• Recurrent identical rearrangement and repeated expression of identical heavy and light chains in single anti-phosphatidylcholine B cells. Seidl KJ,  MacKenzie JD, Wang D, Kantor AB, Kabat EA, Herzenberg LA, Herzenberg LA.  Ann N Y Acad Sci.  1997; 815 484-8
• Development of the antibody repertoire as revealed by single-cell PCR of FACS-sorted B-cell subsets. Kantor AB,  Merrill CE, MacKenzie JD, Herzenberg LA, Hillson JL.  Ann N Y Acad Sci.  1995; 764 224-7