Key Documents

Curriculum Vitae available Online

Carlos Milla

Associate Professor - Med Center Line, Pediatrics - Pulmonary Medicine

Contact Information

Clinical Offices

Respiratory Specialties and ENT 730 Welch Rd 1st Floor Palo Alto, CA 94304
Telephone Work (650) 497-8841 Fax (650) 497-8791
Academic Offices

Personal Information
Email cmilla@stanford.edu Tel (650) 723-5191, (650) 736-9824

Administrative Contact
Linda Zarate Administrative Associate Email lzarate@stanford.edu Tel Work 650-723-5227

Not for medical emergencies or patient use

Clinical Focus

Pediatric Pulmonary
Pulmonary Medicine/Cystic Fibrosis, Pediatric
Pediatric Lung and Heart-Lung Transplantation

Professional Education

Board Certification: Pediatric Pulmonary, American Board of Pediatrics (1996)
University of Minnesota School of Medicine (1995) MN
SUNY @ Brooklyn School Of Medicine (1992) NY
SUNY @ Brooklyn School Of Medicine (1990) NY
Universidad Peruana Cayetano Heredia (1986) APDO 5045 Peru

Clinical Trials

#5901 Primary Ciliary Dyskinesia Study Recruiting
#5902 Rare Genetic Disorders Study Recruiting
HOLA CF Study Recruiting
ISIS Study Recruiting
KaloBios Recruiting
Gilead FTI Study Recruiting
Inspire Open-Label Extension study Recruiting
Mpex 204 Phase 2 Recruiting
NAC Phase IIB: A Multi-Center, Phase IIB, Randomized, Placebo-controlled, Double-Blind Study Of The Effects Of N-Acetylcysteine On Redox Changes and Lung Inflammation In Cystic Fibrosis Patients Recruiting
Vertex 770-102 Study Recruiting
Vertex 809-101 study Recruiting
Altus Phase 3: ALTU-135 No longer recruiting
Inspire Tiger 2 No longer recruiting
Vertex Phase 2a: VX-770 No longer recruiting

Publications

Cystic fibrosis related diabetes. Zirbes J, Milla CE. Paediatr Respir Rev. 2009; 10 (3): 118-23; quiz 123
Longitudinal assessment of lung function from infancy to childhood in patients with cystic fibrosis. Harrison AN, Regelmann WE, Zirbes JM, Milla CE. Pediatr Pulmonol. 2009; 44 (4): 330-9
Nutrition in cystic fibrosis. Matel JL, Milla CE. Semin Respir Crit Care Med. 2009; 30 (5): 579-86
Associations of psychosocial factors with health outcomes among youth with cystic fibrosis. Patterson JM, Wall M, Berge J, Milla C. Pediatr Pulmonol. 2009; 44 (1): 46-53
Gender differences in treatment adherence among youth with cystic fibrosis: development of a new questionnaire. Patterson JM, Wall M, Berge J, Milla C. J Cyst Fibros. 2008; 7 (2): 154-64
Steroid-sparing effect of omalizumab for allergic bronchopulmonary aspergillosis and cystic fibrosis. Zirbes JM, Milla CE. Pediatr Pulmonol. 2008; 43 (6): 607-10
Nutrition and lung disease in cystic fibrosis. Milla CE, Clin Chest Med. 2007; 28 (2): 319-30
Repeated aerosolized AAV-CFTR for treatment of cystic fibrosis: a randomized placebo-controlled phase 2B trial. Moss RB, Milla C, Colombo J, Accurso F, Zeitlin PL, Clancy JP, Spencer LT, Pilewski J, Waltz DA, Dorkin HL, Ferkol T, Pian M, Ramsey B, Carter BJ, Martin DB, Heald AE. Hum Gene Ther. 2007; 18 (8): 726-32
Comparison of high-frequency chest wall oscillation with differing waveforms for airway clearance in cystic fibrosis. Kempainen RR, Williams CB, Hazelwood A, Rubin BK, Milla CE. Chest. 2007; 132 (4): 1227-32
Microvascular complications in cystic fibrosis-related diabetes. Schwarzenberg SJ, Thomas W, Olsen TW, Grover T, Walk D, Milla C, Moran A. Diabetes Care. 2007; 30 (5): 1056-61
Hepatolithiasis and cholangiocarcinoma in cystic fibrosis: a case series and review of the literature. Perdue DG, Cass OW, Milla C, Dunitz J, Jessurun J, Sharp HL, Schwarzenberg SJ. Dig Dis Sci. 2007; 52 (10): 2638-42
Different frequencies should be prescribed for different high frequency chest compression machines. Milla CE, Hansen LG, Warwick WJ. Biomed Instrum Technol. 2006 Jul-Aug; 40 (4): 319-24
Microbiology, safety, and pharmacokinetics of aztreonam lysinate for inhalation in patients with cystic fibrosis. Gibson RL, Retsch-Bogart GZ, Oermann C, Milla C, Pilewski J, Daines C, Ahrens R, Leon K, Cohen M, McNamara S, Callahan TL, Markus R, Burns JL. Pediatr Pulmonol. 2006; 41 (7): 656-65
Cystic fibrosis pulmonary exacerbations. Ferkol T, Rosenfeld M, Milla CE. J Pediatr. 2006; 148 (2): 259-64
Inflammatory cytokines and the development of pulmonary complications after allogeneic hematopoietic cell transplantation in patients with inherited metabolic storage disorders. Kharbanda S, Panoskaltsis-Mortari A, Haddad IY, Blazar BR, Orchard PJ, Cornfield DN, Grewal SS, Peters C, Regelmann WE, Milla CE, Baker KS. Biol Blood Marrow Transplant. 2006; 12 (4): 430-7
Natural history of pulmonary complications in children after bone marrow transplantation. Eikenberry M, Bartakova H, Defor T, Haddad IY, Ramsay NK, Blazar BR, Milla CE, Cornfield DN. Biol Blood Marrow Transplant. 2005; 11 (1): 56-64
Altered airway responsiveness in CD38-deficient mice. Deshpande DA, White TA, Guedes AG, Milla C, Walseth TF, Lund FE, Kannan MS. Am J Respir Cell Mol Biol. 2005; 32 (2): 149-56
Diabetes is associated with dramatically decreased survival in female but not male subjects with cystic fibrosis. Milla CE, Billings J, Moran A. Diabetes Care. 2005; 28 (9): 2141-4
Safety and tolerability of denufosol tetrasodium inhalation solution, a novel P2Y2 receptor agonist: results of a phase 1/phase 2 multicenter study in mild to moderate cystic fibrosis. Deterding R, Retsch-Bogart G, Milgram L, Gibson R, Daines C, Zeitlin PL, Milla C, Marshall B, Lavange L, Engels J, Mathews D, Gorden J, Schaberg A, Williams J, Ramsey B. Pediatr Pulmonol. 2005; 39 (4): 339-48
Absence of host tumor necrosis factor receptor 1 attenuates manifestations of idiopathic pneumonia syndrome. Shukla M, Yang S, Milla C, Panoskaltsis-Mortari A, Blazar BR, Haddad IY. Am J Physiol Lung Cell Mol Physiol. 2005; 288 (5): L942-9
High-frequency chest compression: effect of the third generation compression waveform. Milla CE, Hansen LG, Weber A, Warwick WJ. Biomed Instrum Technol. 2004 Jul-Aug; 38 (4): 322-8
Association of nutritional status and pulmonary function in children with cystic fibrosis. Milla CE, Curr Opin Pulm Med. 2004; 10 (6): 505-9
Myeloperoxidase deficiency enhances inflammation after allogeneic marrow transplantation. Milla C, Yang S, Cornfield DN, Brennan ML, Hazen SL, Panoskaltsis-Mortari A, Blazar BR, Haddad IY. Am J Physiol Lung Cell Mol Physiol. 2004; 287 (4): L706-14
Peroxidase activity within circulating neutrophils correlates with pulmonary phenotype in cystic fibrosis. Garner HP, Phillips JR, Herron JG, Severson SJ, Milla CE, Regelmann WE. J Lab Clin Med. 2004; 144 (3): 127-33
Repeated adeno-associated virus serotype 2 aerosol-mediated cystic fibrosis transmembrane regulator gene transfer to the lungs of patients with cystic fibrosis: a multicenter, double-blind, placebo-controlled trial. Moss RB, Rodman D, Spencer LT, Aitken ML, Zeitlin PL, Waltz D, Milla C, Brody AS, Clancy JP, Ramsey B, Hamblett N, Heald AE. Chest. 2004; 125 (2): 509-21
Insulin regulation of free fatty acid kinetics in adult cystic fibrosis patients with impaired glucose tolerance. Moran A, Basu R, Milla C, Jensen MD. Metabolism. 2004; 53 (11): 1467-72
Methodologic advancements in the study of airway smooth muscle. Kotlikoff MI, Kannan MS, Solway J, Deng KY, Deshpande DA, Dowell M, Feldman M, Green KS, Ji G, Johnston R, Lakser O, Lee J, Lund FE, Milla C, Mitchell RW, Nakai J, Rishniw M, Walseth TF, White TA, Wilson J, Xin HB, Woodruff PG. J Allergy Clin Immunol. 2004; 114 (2 Suppl): S18-31
Longitudinal changes in growth parameters are correlated with changes in pulmonary function in children with cystic fibrosis. Peterson ML, Jacobs DR, Milla CE. Pediatrics. 2003; 112 (3 Pt 1): 588-92
Safety of inhaled nitric oxide after lung transplantation. Cornfield DN, Milla CE, Haddad IY, Barbato JE, Park SJ. J Heart Lung Transplant. 2003; 22 (8): 903-7
Abnormal glucose tolerance in cystic fibrosis: why should patients be screened? Moran A, Milla C. J Pediatr. 2003; 142 (2): 97-9
Surfactant protein A is a required mediator of keratinocyte growth factor after experimental marrow transplantation. Haddad IY, Milla C, Yang S, Panoskaltsis-Mortari A, Hawgood S, Lacey DL, Blazar BR. Am J Physiol Lung Cell Mol Physiol. 2003; 285 (3): L602-10
Insulin glargine improves hemoglobin A1c in children and adolescents with poorly controlled type 1 diabetes. Jackson A, Ternand C, Brunzell C, Kleinschmidt T, Dew D, Milla C, Moran A. Pediatr Diabetes. 2003; 4 (2): 64-9
Continuous propofol infusion in 142 critically ill children. Cornfield DN, Tegtmeyer K, Nelson MD, Milla CE, Sweeney M. Pediatrics. 2002; 110 (6): 1177-81
Surfactant protein A decreases lung injury and mortality after murine marrow transplantation. Yang S, Milla C, Panoskaltsis-Mortari A, Hawgood S, Blazar BR, Haddad IY. Am J Respir Cell Mol Biol. 2002; 27 (3): 297-305
Abnormal lipid concentrations in cystic fibrosis. Figueroa V, Milla C, Parks EJ, Schwarzenberg SJ, Moran A. Am J Clin Nutr. 2002; 75 (6): 1005-11
Human surfactant protein a suppresses T cell-dependent inflammation and attenuates the manifestations of idiopathic pneumonia syndrome in mice. Yang S, Milla C, Panoskaltsis-Mortari A, Ingbar DH, Blazar BR, Haddad IY. Am J Respir Cell Mol Biol. 2001; 24 (5): 527-36
Effects of oxidant stress on inflammation and survival of iNOS knockout mice after marrow transplantation. Yang S, Porter VA, Cornfield DN, Milla C, Panoskaltsis-Mortari A, Blazar BR, Haddad IY. Am J Physiol Lung Cell Mol Physiol. 2001; 281 (4): L922-30
Insulin and glucose excursion following premeal insulin lispro or repaglinide in cystic fibrosis-related diabetes. Moran A, Phillips J, Milla C. Diabetes Care. 2001; 24 (10): 1706-10
Protein metabolism in clinically stable adult cystic fibrosis patients with abnormal glucose tolerance. Moran A, Milla C, Ducret R, Nair KS. Diabetes. 2001; 50 (6): 1336-43
Trends in pulmonary function in patients with cystic fibrosis correlate with the degree of glucose intolerance at baseline. Milla CE, Warwick WJ, Moran A. Am J Respir Crit Care Med. 2000; 162 (3 Pt 1): 891-5
Recombinant human DNase in cystic fibrosis. Milla CE, Lancet. 1999; 354 (9176): 428
NO causes perinatal pulmonary vasodilation through K+-channel activation and intracellular Ca2+ release. Saqueton CB, Miller RB, Porter VA, Milla CE, Cornfield DN. Am J Physiol. 1999; 276 (6 Pt 1): L925-32
High levels of peroxynitrite are generated in the lungs of irradiated mice given cyclophosphamide and allogeneic T cells. A potential mechanism of injury after marrow transplantation. Haddad IY, Panoskaltsis-Mortari A, Ingbar DH, Yang S, Milla CE, Blazar BR. Am J Respir Cell Mol Biol. 1999; 20 (6): 1125-35
Allergic bronchopulmonary aspergillosis and cystic fibrosis. Milla CE, Pediatr Pulmonol. 1999; 27 (2): 71-3
Randomized, controlled trial of low-dose inhaled nitric oxide in the treatment of term and near-term infants with respiratory failure and pulmonary hypertension. Cornfield DN, Maynard RC, deRegnier RA, Guiang SF, Barbato JE, Milla CE. Pediatrics. 1999; 104 (5 Pt 1): 1089-94
Long-term effects of aerosolised rhDNase on pulmonary disease progression in patients with cystic fibrosis. Milla CE, Thorax. 1998; 53 (12): 1014-7
Effects of inhaled nitric oxide and oxygen in high-altitude pulmonary edema. Anand IS, Prasad BA, Chugh SS, Rao KR, Cornfield DN, Milla CE, Singh N, Singh S, Selvamurthy W. Circulation. 1998; 98 (22): 2441-5
Risk of death in cystic fibrosis patients with severely compromised lung function. Milla CE, Warwick WJ. Chest. 1998; 113 (5): 1230-4
PCR ribotyping and endonuclease subtyping in the epidemiology of Burkholderia cepacia infection. Shreve MR, Johnson SJ, Milla CE, Wielinski CL, Regelmann WE. Am J Respir Crit Care Med. 1997; 155 (3): 984-9
Glycemic response to dietary supplements in cystic fibrosis is dependent on the carbohydrate content of the formula. Milla C, Doherty L, Raatz S, Schwarzenberg SJ, Regelmann W, Moran A. JPEN J Parenter Enteral Nutr. 1996 May-Jun; 20 (3): 182-6
Clinical significance of the recovery of Aspergillus species from the respiratory secretions of cystic fibrosis patients. Milla CE, Wielinski CL, Regelmann WE. Pediatr Pulmonol. 1996; 21 (1): 6-10
High-strength pancreatic enzymes. Milla CE, Wielinski CL, Warwick WJ. Lancet. 1994; 343 (8897): 599
Influence of the mesocortical/prefrontal dopamine neurons on their target cells. Thierry AM, Mantz J, Milla C, Glowinski J. Ann N Y Acad Sci. 1988; 537 101-11
Differential effects of ascending neurons containing dopamine and noradrenaline in the control of spontaneous activity and of evoked responses in the rat prefrontal cortex. Mantz J, Milla C, Glowinski J, Thierry AM. Neuroscience. 1988; 27 (2): 517-26
[Usefulness of mechanical sutures in colorectal reconstruction after intervention by the Hartmann method] Vicens A, Piulachs J, Suñol J, Milla C, Villa R. Rev Esp Enferm Apar Dig. 1987; 72 (5 Pt 1): 527-32