Daniel Kraft, MD

Honors and Awards

• Young Investigator Award, American Society for Bone Marrow Transplantation (ASBMT) (2008)
• Research Award, Hope Street Kids Foundation (2006)
• Clinical Scientist Developmental Award (K-08), NHLBI/NIH (2005)
• Astronaut selection finalist (Mission Specialist), NASA (2004)
• National Innovation grant: Collegiate Inventors and Innovators Alliance, NCIIA (2003)
• Research Fellowship, Pediatric Scientist Development Program (PSDP) (2002)
• Innovation Grant, National Collegiate Inventors & Innovators Alliance (NCIIA) (2002)
• Dean's Award for Research, Stanford Medical School (1996)
• HHMI Research Training Fellowship, Howard Hughes Medical Institute (1992-5)

Professional Education

• Fellowship, Stanford University Bone Marrow Transplantation (2002)
• Fellowship, Stanford University Pediatric Hematology/Oncology (2004)
• Residency, Harvard University Internal Medicine & Pediatrics (2000)
• M.D., Stanford University Medicine (1996)
• B.A., Brown University Biochemistry, cum laude (1990)

Community & International Work

• Flight Surgeon, California Air National Guard More »

Research Interests

-Stem cell biology & Regenerative Medicine

-Stem Cell Derived Immunotherapy for Cancer

-BioEngineering

-The hematopoietic stem cell niche in murine and human systems

-Human T cell differentiation

-Humanized animal models

-Clinical focus: Bone Marrow/Hematopoietic Stem cell transplantation for malignant and non-malignant diseases in adults & children

-Medical devices to enable stem cell based regenerative medicine, to include marrow derived stem cell harvest, processing and delivery

Publications

• Endochondral ossification is required for haematopoietic stem-cell niche formation. Chan CK,  Chen CC, Luppen CA, Kim JB, DeBoer AT, Wei K, Helms JA, Kuo CJ, Kraft DL, Weissman IL.  Nature.  2009; 457 (7228): 490-4
• Efficient transplantation via antibody-based clearance of hematopoietic stem cell niches. Czechowicz A,  Kraft D, Weissman IL, Bhattacharya D.  Science.  2007; 318 (5854): 1296-9
• Efficacy of a Novel, Minimally Invasive Bone Marrow Harvesting Device in Pre-Clinical Evaluation and First Human Use Kraft D,  Song, Crocker, M, Moseley A, Long M, Vina R, Ghazarossian V.  Biology of Blood and Marrow Transplantation.  2008; 14 (2:128)
• Differentiation, survival, and function of embryonic stem cell derived endothelial cells for ischemic heart disease. Li Z,  Wu JC, Sheikh AY, Kraft D, Cao F, Xie X, Patel M, Gambhir SS, Robbins RC, Cooke JP, Wu JC.  Circulation.  2007; 116 (11 Suppl): I46-54
• Porcine thymic grafts protect human thymocytes from HIV-1-induced destruction. Hongo D,  Hadidi S, Damrauer S, Garrigue V, Kraft D, Sachs DH, Nikolic B, Sykes M.  J Infect Dis.  2007; 196 (6): 900-10
• Hematopoietic Stem Cells- Basic Science and Clinical Applications Kraft D,  Weissman IL.  Stem Cells from Bench to Bedside (World Press).  2005; 253-292
• Detection and characterization of cellular immune responses using peptide-MHC microarrays. Soen Y,  Chen DS, Kraft DL, Davis MM, Brown PO.  PLoS Biol.  2003; 1 (3): E65
• Venoconstrictive thigh cuffs impede fluid shifts during simulated microgravity. Lindgren KN,  Kraft D, Ballard RE, Tucker A, Hargens AR.  Aviat Space Environ Med.  1998; 69 (11): 1052-8
• HIV-1-induced thymocyte depletion is associated with indirect cytopathogenicity and infection of progenitor cells in vivo. Su L,  Kaneshima H, Bonyhadi M, Salimi S, Kraft D, Rabin L, McCune JM.  Immunity.  1995; 2 (1): 25-36
• Differentiation of CD3-4-8- human fetal thymocytes in vivo: characterization of a CD3-4+8- intermediate. Kraft DL,  Weissman IL, Waller EK.  J Exp Med.  1993; 178 (1): 265-77
• Inhibition of allergic reactions with monoclonal antibody to the high affinity IgE receptor. Kitani S,  Kraft D, Fischler C, Mergenhagen SE, Siraganian RP.  J Immunol.  1988; 140 (8): 2585-8