Brian Hargreaves

Professional Education

• Ph.D., Stanford University Electrical Engineering (2001)
• M.S., Stanford University Electrical Engineering (1997)
• B.A.Sc, Simon Fraser University Engineering Science (1994)

Postdoctoral Advisees

• Kyunghyun Sung, Pauline Worters

Web Site Links

• Research Group Site

Research Interests

I am interested in magnetic resonance imaging (MRI) applications including cardiovascular, abdominal, breast and musculoskeletal imaging. These applications require development of faster and more efficient MRI methods that provide improved diagnostic contrast compared with current methods. My work includes novel excitation schemes, efficient imaging methods and reconstruction tools. Please see my research site (above) for most up-to-date information.

Clinical Trials

• Effects of an herbal topical cream on osteoarthritis symptoms, biomarkers, and disease progression in the knee No longer recruiting

Publications

• Independent phase modulation for efficient dual-band 3D imaging. Hargreaves BA,  Cunningham CH, Pauly JM, Daniel BL.  Magn Reson Med.  2007; 57 (4): 798-802
• Dual-acquisition phase-sensitive fat-water separation using balanced steady-state free precession. Hargreaves BA,  Bangerter NK, Shimakawa A, Vasanawala SS, Brittain JH, Nishimura DG.  Magn Reson Imaging.  2006; 24 (2): 113-22
• Time-optimal multidimensional gradient waveform design for rapid imaging. Hargreaves BA,  Nishimura DG, Conolly SM.  Magn Reson Med.  2004; 51 (1): 81-92
• Variable-rate selective excitation for rapid MRI sequences. Hargreaves BA,  Cunningham CH, Nishimura DG, Conolly SM.  Magn Reson Med.  2004; 52 (3): 590-7
• Fat-suppressed steady-state free precession imaging using phase detection. Hargreaves BA,  Vasanawala SS, Nayak KS, Hu BS, Nishimura DG.  Magn Reson Med.  2003; 50 (1): 210-3
• Comparison of new sequences for high-resolution cartilage imaging. Hargreaves BA,  Gold GE, Beaulieu CF, Vasanawala SS, Nishimura DG, Pauly JM.  Magn Reson Med.  2003; 49 (4): 700-9
• SEMAC: Slice Encoding for Metal Artifact Correction in MRI. Lu W,  Pauly KB, Gold GE, Pauly JM, Hargreaves BA.  Magn Reson Med.  2009; 62 (1): 66-76
• Non-contrast-enhanced flow-independent peripheral MR angiography with balanced SSFP. Cukur T,  Lee JH, Bangerter NK, Hargreaves BA, Nishimura DG.  Magn Reson Med.  2009; 61 (6): 1533-9
• MRI guidance for accelerated partial breast irradiation in prone position: imaging protocol design and evaluation. Ahn KH,  Hargreaves BA, Alley MT, Horst KC, Luxton G, Daniel BL, Hristov D.  Int J Radiat Oncol Biol Phys.  2009; 75 (1): 285-93
• Independent slab-phase modulation combined with parallel imaging in bilateral breast MRI. Han M,  Beatty PJ, Daniel BL, Hargreaves BA.  Magn Reson Med.  2009; 62 (5): 1221-31
• Multiecho IDEAL gradient-echo water-fat separation for rapid assessment of cartilage volume at 1.5 T: initial experience. Chen CA,  Lu W, John CT, Hargreaves BA, Reeder SB, Delp SL, Siston RA, Gold GE.  Radiology.  2009; 252 (2): 561-7
• Recent advances in MRI of articular cartilage. Gold GE,  Chen CA, Koo S, Hargreaves BA, Bangerter NK.  AJR Am J Roentgenol.  2009; 193 (3): 628-38
• Accelerated bilateral dynamic contrast-enhanced 3D spiral breast MRI using TSENSE. Han M,  Daniel BL, Hargreaves BA.  J Magn Reson Imaging.  2008; 28 (6): 1425-34
• Water-fat separation with bipolar multiecho sequences. Lu W,  Yu H, Shimakawa A, Alley M, Reeder SB, Hargreaves BA.  Magn Reson Med.  2008; 60 (1): 198-209
• Multiresolution field map estimation using golden section search for water-fat separation. Lu W,  Hargreaves BA.  Magn Reson Med.  2008; 60 (1): 236-44
• Water-fat separation with IDEAL gradient-echo imaging. Reeder SB,  McKenzie CA, Pineda AR, Yu H, Shimakawa A, Brau AC, Hargreaves BA, Gold GE, Brittain JH.  J Magn Reson Imaging.  2007; 25 (3): 644-52
• Wideband SSFP: alternating repetition time balanced steady state free precession with increased band spacing. Nayak KS,  Lee HL, Hargreaves BA, Hu BS.  Magn Reson Med.  2007; 58 (5): 931-8
• Balanced SSFP imaging of the musculoskeletal system. Gold GE,  Hargreaves BA, Reeder SB, Block WF, Kijowski R, Vasanawala SS, Kornaat PR, Bammer R, Newbould R, Bangerter NK, Beaulieu CF.  J Magn Reson Imaging.  2007; 25 (2): 270-8
• Design and analysis of a practical 3D cones trajectory. Gurney PT,  Hargreaves BA, Nishimura DG.  Magn Reson Med.  2006; 55 (3): 575-82
• Articular cartilage of the knee: evaluation with fluctuating equilibrium MR imaging--initial experience in healthy volunteers. Gold GE,  Hargreaves BA, Vasanawala SS, Webb JD, Shimakawa AS, Brittain JH, Beaulieu CF.  Radiology.  2006; 238 (2): 712-8
• Single breath-hold whole-heart MRA using variable-density spirals at 3T. Santos JM,  Cunningham CH, Lustig M, Hargreaves BA, Hu BS, Nishimura DG, Pauly JM.  Magn Reson Med.  2006; 55 (2): 371-9
• Respiration-induced B0 field fluctuation compensation in balanced SSFP: real-time approach for transition-band SSFP fMRI. Lee J,  Santos JM, Conolly SM, Miller KL, Hargreaves BA, Pauly JM.  Magn Reson Med.  2006; 55 (5): 1197-201
• Fluid-attenuated inversion-recovery SSFP imaging. Bangerter NK,  Hargreaves BA, Gold GE, Stucker DT, Nishimura DG.  J Magn Reson Imaging.  2006; 24 (6): 1426-31
• Linear combination filtering for T2-selective imaging of the knee. Vidarsson L,  Gold GE, Hargreaves B, Pauly JM.  Magn Reson Med.  2006; 55 (5): 1191-6
• Advanced magnetic resonance imaging of articular cartilage. Gold GE,  Hargreaves BA, Stevens KJ, Beaulieu CF.  Orthop Clin North Am.  2006; 37 (3): 331-47, vi
• Driven equilibrium magnetic resonance imaging of articular cartilage: initial clinical experience. Gold GE,  Fuller SE, Hargreaves BA, Stevens KJ, Beaulieu CF.  J Magn Reson Imaging.  2005; 21 (4): 476-81
• Variable-density one-shot Fourier velocity encoding. DiCarlo JC,  Hargreaves BA, Nayak KS, Hu BS, Pauly JM, Nishimura DG.  Magn Reson Med.  2005; 54 (3): 645-55
• Controversies in protocol selection in the imaging of articular cartilage. Gold GE,  Hargreaves BA, Reeder SB, Vasanawala SS, Beaulieu CF.  Semin Musculoskelet Radiol.  2005; 9 (2): 161-72
• Spiral balanced steady-state free precession cardiac imaging. Nayak KS,  Hargreaves BA, Hu BS, Nishimura DG, Pauly JM, Meyer CH.  Magn Reson Med.  2005; 53 (6): 1468-73
• Rapid measurement of renal artery blood flow with ungated spiral phase-contrast MRI. Park JB,  Santos JM, Hargreaves BA, Nayak KS, Sommer G, Hu BS, Nishimura DG.  J Magn Reson Imaging.  2005; 21 (5): 590-5
• Rapid musculoskeletal MRI with phase-sensitive steady-state free precession: comparison with routine knee MRI. Vasanawala SS,  Hargreaves BA, Pauly JM, Nishimura DG, Beaulieu CF, Gold GE.  AJR Am J Roentgenol.  2005; 184 (5): 1450-5
• Automatic tuning of flexible interventional RF receiver coils. Venook RD,  Hargreaves BA, Gold GE, Conolly SM, Scott GC.  Magn Reson Med.  2005; 54 (4): 983-93
• Magnetic resonance imaging of articular cartilage of the knee: comparison between fat-suppressed three-dimensional SPGR imaging, fat-suppressed FSE imaging, and fat-suppressed three-dimensional DEFT imaging, and correlation with arthroscopy. Yoshioka H,  Stevens K, Hargreaves BA, Steines D, Genovese M, Dillingham MF, Winalski CS, Lang P.  J Magn Reson Imaging.  2004; 20 (5): 857-64
• Steady-state diffusion-weighted imaging of in vivo knee cartilage. Miller KL,  Hargreaves BA, Gold GE, Pauly JM.  Magn Reson Med.  2004; 51 (2): 394-8
• Analysis of multiple-acquisition SSFP. Bangerter NK,  Hargreaves BA, Vasanawala SS, Pauly JM, Gold GE, Nishimura DG.  Magn Reson Med.  2004; 51 (5): 1038-47
• Fast 3D imaging using variable-density spiral trajectories with applications to limb perfusion. Lee JH,  Hargreaves BA, Hu BS, Nishimura DG.  Magn Reson Med.  2003; 50 (6): 1276-85
• Protocols in sports magnetic resonance imaging. Gold GE,  Hargreaves BA, Beaulieu CF.  Top Magn Reson Imaging.  2003; 14 (1): 3-23
• Functional brain imaging using a blood oxygenation sensitive steady state. Miller KL,  Hargreaves BA, Lee J, Ress D, deCharms RC, Pauly JM.  Magn Reson Med.  2003; 50 (4): 675-83
• Characterization and reduction of the transient response in steady-state MR imaging. Hargreaves BA,  Vasanawala SS, Pauly JM, Nishimura DG.  Magn Reson Med.  2001; 46 (1): 149-58
• MR imaging of articular cartilage using driven equilibrium. Hargreaves BA,  Gold GE, Lang PK, Conolly SM, Pauly JM, Bergman G, Vandevenne J, Nishimura DG.  Magn Reson Med.  1999; 42 (4): 695-703
• Magnetic resonance imaging of knee cartilage repair. Gold GE,  Bergman AG, Pauly JM, Lang P, Butts RK, Beaulieu CF, Hargreaves B, Frank L, Boutin RD, Macovski A, Resnick D.  Top Magn Reson Imaging.  1998; 9 (6): 377-92