Scott L. Delp, Ph.D.

Administrative Appointments

• Chairman, Bioengineering Department , (2002– 2007 )
• Co-Director, Center for Biomedical Computation , (2001– present )
• Chairman, Biomechanical Engineering Division , (2000– 2002 )

Honors and Awards

• James H. Clark Professor, Stanford University (2009-)
• Van C. Mow Medal, Am Soc. Mech. Eng (2008)
• Charles Lee Powell Professor, Stanford University (2006-2009)
• Distinguished Alumnus Award, Colorado State University (2005)
• Maurice E Muller Award, Excellence in Computer Assisted Surgery (2004)
• Fellow, American Institute of Biological and Medical Engineers (2003)
• Powell Faculty Scholar, Stanford University (2000)
• National Young Investigator Award, NSF (1992-1998)
• Technology Reinvestment Award, White House (1993)
• Baxter Faculty Fellow, Baxter Foundation (1991)

Professional Education

• Ph.D., Stanford University Mechanical Engineering (1990)
• M.S., Stanford University Mechanical Engineering (1986)
• B.S., Colorado State University Mechanical Engineering (1983)

Graduate & Fellowship Program Affiliations

• Biomechanical Engineering
• Neurosciences
• Bioengineering

Web Site Links

• Neuromuscular Biomechanics Lab

Research Interests

Experimental and computational approaches to study human movement. Development of biomechanical models to analyze muscle function, study movement abnormalities, design new medical products, and guide surgery. Testing of new computational models of human movement with medical image data and experimental measurements.

Publications

• Knee muscle forces during walking and running in patellofemoral pain patients and pain-free controls. Besier TF,  Fredericson M, Gold GE, Beaupré GS, Delp SL.  J Biomech.  2009; 42 (7): 898-905
• Mechanisms of improved knee flexion after rectus femoris transfer surgery. Fox MD,  Reinbolt JA, Ounpuu S, Delp SL.  J Biomech.  2009; 42 (5): 614-9
• Predicting outcomes of rectus femoris transfer surgery. Reinbolt JA,  Fox MD, Schwartz MH, Delp SL.  Gait Posture.  2009; 30 (1): 100-5
• Multiecho IDEAL gradient-echo water-fat separation for rapid assessment of cartilage volume at 1.5 T: initial experience. Chen CA,  Lu W, John CT, Hargreaves BA, Reeder SB, Delp SL, Siston RA, Gold GE.  Radiology.  2009; 252 (2): 561-7
• Engineered myosin VI motors reveal minimal structural determinants of directionality and processivity. Liao JC,  Elting MW, Delp SL, Spudich JA, Bryant Z.  J Mol Biol.  2009; 392 (4): 862-7
• Using real-time MRI to quantify altered joint kinematics in subjects with patellofemoral pain and to evaluate the effects of a patellar brace or sleeve on joint motion. Draper CE,  Besier TF, Santos JM, Jennings F, Fredericson M, Gold GE, Beaupre GS, Delp SL.  J Orthop Res.  2009; 27 (5): 571-7
• Crouched postures reduce the capacity of muscles to extend the hip and knee during the single-limb stance phase of gait. Hicks JL,  Schwartz MH, Arnold AS, Delp SL.  J Biomech.  2008; 41 (5): 960-7
• Minimally invasive high-speed imaging of sarcomere contractile dynamics in mice and humans. Llewellyn ME,  Barretto RP, Delp SL, Schnitzer MJ.  Nature.  2008; 454 (7205): 784-8
• Feasibility of using real-time MRI to measure joint kinematics in 1.5T and open-bore 0.5T systems. Draper CE,  Santos JM, Kourtis LC, Besier TF, Fredericson M, Beaupre GS, Gold GE, Delp SL.  J Magn Reson Imaging.  2008; 28 (1): 158-66
• The influence of femoral internal and external rotation on cartilage stresses within the patellofemoral joint. Besier TF,  Gold GE, Delp SL, Fredericson M, Beaupré GS.  J Orthop Res.  2008; 26 (12): 1627-35
• Posterior cruciate ligament removal contributes to abnormal knee motion during posterior stabilized total knee arthroplasty. Cromie MJ,  Siston RA, Giori NJ, Delp SL.  J Orthop Res.  2008; 26 (11): 1494-9
• Importance of preswing rectus femoris activity in stiff-knee gait. Reinbolt JA,  Fox MD, Arnold AS, Ounpuu S, Delp SL.  J Biomech.  2008; 41 (11): 2362-9
• Muscle contributions to support and progression over a range of walking speeds. Liu MQ,  Anderson FC, Schwartz MH, Delp SL.  J Biomech.  2008; 41 (15): 3243-52
• Contributions of muscles to terminal-swing knee motions vary with walking speed. Arnold AS,  Schwartz MH, Thelen DG, Delp SL.  J Biomech.  2007; 40 (16): 3660-71
• Coronal plane stability before and after total knee arthroplasty. Siston RA,  Goodman SB, Delp SL, Giori NJ.  Clin Orthop Relat Res.  2007; 463 43-9
• OpenSim: open-source software to create and analyze dynamic simulations of movement. Delp SL,  Anderson FC, Arnold AS, Loan P, Habib A, John CT, Guendelman E, Thelen DG.  IEEE Trans Biomed Eng.  2007; 54 (11): 1940-50
• Moment-generating capacity of upper limb muscles in healthy adults. Holzbaur KR,  Delp SL, Gold GE, Murray WM.  J Biomech.  2007; 40 (11): 2442-9
• Upper limb muscle volumes in adult subjects. Holzbaur KR,  Murray WM, Gold GE, Delp SL.  J Biomech.  2007; 40 (4): 742-9
• Surgical navigation for total knee arthroplasty: a perspective. Siston RA,  Giori NJ, Goodman SB, Delp SL.  J Biomech.  2007; 40 (4): 728-35
• Muscular coordination of knee motion during the terminal-swing phase of normal gait. Arnold AS,  Thelen DG, Schwartz MH, Anderson FC, Delp SL.  J Biomech.  2007; 40 (15): 3314-24
• Extending the absorbing boundary method to fit dwell-time distributions of molecular motors with complex kinetic pathways. Liao JC,  Spudich JA, Parker D, Delp SL.  Proc Natl Acad Sci U S A.  2007; 104 (9): 3171-6
• Rectus femoris and vastus intermedius fiber excursions predicted by three-dimensional muscle models. Blemker SS,  Delp SL.  J Biomech.  2006; 39 (8): 1383-91
• Muscle contributions to support during gait in an individual with post-stroke hemiparesis. Higginson JS,  Zajac FE, Neptune RR, Kautz SA, Delp SL.  J Biomech.  2006; 39 (10): 1769-77
• Do the hamstrings operate at increased muscle-tendon lengths and velocities after surgical lengthening? Arnold AS,  Liu MQ, Schwartz MH, Ounpuu S, Dias LS, Delp SL.  J Biomech.  2006; 39 (8): 1498-506
• Evaluation of a new algorithm to determine the hip joint center. Siston RA,  Delp SL.  J Biomech.  2006; 39 (1): 125-30
• Muscles that support the body also modulate forward progression during walking. Liu MQ,  Anderson FC, Pandy MG, Delp SL.  J Biomech.  2006; 39 (14): 2623-30
• The role of estimating muscle-tendon lengths and velocities of the hamstrings in the evaluation and treatment of crouch gait. Arnold AS,  Liu MQ, Schwartz MH, Ounpuu S, Delp SL.  Gait Posture.  2006; 23 (3): 273-81
• The high variability of tibial rotational alignment in total knee arthroplasty. Siston RA,  Goodman SB, Patel JJ, Delp SL, Giori NJ.  Clin Orthop Relat Res.  2006; 452 65-9
• Intraoperative passive kinematics of osteoarthritic knees before and after total knee arthroplasty. Siston RA,  Giori NJ, Goodman SB, Delp SL.  J Orthop Res.  2006; 24 (8): 1607-14
• Effect of equinus foot placement and intrinsic muscle response on knee extension during stance. Higginson JS,  Zajac FE, Neptune RR, Kautz SA, Burgar CG, Delp SL.  Gait Posture.  2006; 23 (1): 32-6
• Kinematic and kinetic factors that correlate with improved knee flexion following treatment for stiff-knee gait. Goldberg SR,  Ounpuu S, Arnold AS, Gage JR, Delp SL.  J Biomech.  2006; 39 (4): 689-98
• Is cartilage thickness different in young subjects with and without patellofemoral pain? Draper CE,  Besier TF, Gold GE, Fredericson M, Fiene A, Beaupre GS, Delp SL.  Osteoarthritis Cartilage.  2006; 14 (9): 931-7
• Dynamic magnetic resonance imaging of muscle function after surgery. Asakawa DS,  Blemker SS, Gold GE, Delp SL.  Skeletal Radiol.  2006; 35 (12): 885-6
• The variability of femoral rotational alignment in total knee arthroplasty. Siston RA,  Patel JJ, Goodman SB, Delp SL, Giori NJ.  J Bone Joint Surg Am.  2005; 87 (10): 2276-80
• Evaluation of methods that locate the center of the ankle for computer-assisted total knee arthroplasty. Siston RA,  Daub AC, Giori NJ, Goodman SB, Delp SL.  Clin Orthop Relat Res.  2005; 439 129-35
• Muscular contributions to hip and knee extension during the single limb stance phase of normal gait: a framework for investigating the causes of crouch gait. Arnold AS,  Anderson FC, Pandy MG, Delp SL.  J Biomech.  2005; 38 (11): 2181-9
• A model of the upper extremity for simulating musculoskeletal surgery and analyzing neuromuscular control. Holzbaur KR,  Murray WM, Delp SL.  Ann Biomed Eng.  2005; 33 (6): 829-40
• Three-dimensional representation of complex muscle architectures and geometries. Blemker SS,  Delp SL.  Ann Biomed Eng.  2005; 33 (5): 661-73
• A 3D model of muscle reveals the causes of nonuniform strains in the biceps brachii. Blemker SS,  Pinsky PM, Delp SL.  J Biomech.  2005; 38 (4): 657-65
• Patellofemoral joint contact area increases with knee flexion and weight-bearing. Besier TF,  Draper CE, Gold GE, Beaupré GS, Delp SL.  J Orthop Res.  2005; 23 (2): 345-50
• A modeling framework to estimate patellofemoral joint cartilage stress in vivo. Besier TF,  Gold GE, Beaupré GS, Delp SL.  Med Sci Sports Exerc.  2005; 37 (11): 1924-30
• Magnetic resonance imaging findings after rectus femoris transfer surgery. Gold GE,  Asakawa DS, Blemker SS, Delp SL.  Skeletal Radiol.  2004; 33 (1): 34-40
• Weight-bearing MRI of patellofemoral joint cartilage contact area. Gold GE,  Besier TF, Draper CE, Asakawa DS, Delp SL, Beaupre GS.  J Magn Reson Imaging.  2004; 20 (3): 526-30
• Muscles that influence knee flexion velocity in double support: implications for stiff-knee gait. Goldberg SR,  Anderson FC, Pandy MG, Delp SL.  J Biomech.  2004; 37 (8): 1189-96
• Contributions of muscle forces and toe-off kinematics to peak knee flexion during the swing phase of normal gait: an induced position analysis. Anderson FC,  Goldberg SR, Pandy MG, Delp SL.  J Biomech.  2004; 37 (5): 731-7
• Three-dimensional muscle-tendon geometry after rectus femoris tendon transfer. Asakawa DS,  Blemker SS, Rab GT, Bagley A, Delp SL.  J Bone Joint Surg Am.  2004; 86-A (2): 348-54
• Abnormal coupling of knee and hip moments during maximal exertions in persons with cerebral palsy. Thelen DD,  Riewald SA, Asakawa DS, Sanger TD, Delp SL.  Muscle Nerve.  2003; 27 (4): 486-93
• The importance of swing-phase initial conditions in stiff-knee gait. Goldberg SR,  Ounpuu S, Delp SL.  J Biomech.  2003; 36 (8): 1111-6
• Cine phase-contrast magnetic resonance imaging as a tool for quantification of skeletal muscle motion. Asakawa DS,  Pappas GP, Blemker SS, Drace JE, Delp SL.  Semin Musculoskelet Radiol.  2003; 7 (4): 287-95
• Biomechanics of the Steindler flexorplasty surgery: a computer simulation study. Saul KR,  Murray WM, Hentz VR, Delp SL.  J Hand Surg Am.  2003; 28 (6): 979-86
• Real-time imaging of skeletal muscle velocity. Asakawa DS,  Nayak KS, Blemker SS, Delp SL, Pauly JM, Nishimura DG, Gold GE.  J Magn Reson Imaging.  2003; 18 (6): 734-9
• In vivo motion of the rectus femoris muscle after tendon transfer surgery. Asakawa DS,  Blemker SS, Gold GE, Delp SL.  J Biomech.  2002; 35 (8): 1029-37
• Nonuniform shortening in the biceps brachii during elbow flexion. Pappas GP,  Asakawa DS, Delp SL, Zajac FE, Drace JE.  J Appl Physiol.  2002; 92 (6): 2381-9
• Scaling of peak moment arms of elbow muscles with upper extremity bone dimensions. Murray WM,  Buchanan TS, Delp SL.  J Biomech.  2002; 35 (1): 19-26
• Rotational moment arms of the medial hamstrings and adductors vary with femoral geometry and limb position: implications for the treatment of internally rotated gait. Arnold AS,  Delp SL.  J Biomech.  2001; 34 (4): 437-47
• Evaluation of a deformable musculoskeletal model for estimating muscle-tendon lengths during crouch gait. Arnold AS,  Blemker SS, Delp SL.  Ann Biomed Eng.  2001; 29 (3): 263-74
• Architecture of the rectus abdominis, quadratus lumborum, and erector spinae. Delp SL,  Suryanarayanan S, Murray WM, Uhlir J, Triolo RJ.  J Biomech.  2001; 34 (3): 371-5