Phillip Yang, MD

Clinical Focus

• Cardiology (Heart)
• Cardiovascular Medicine

Administrative Appointments

• Assistant Professor, Stanford Division of Cardiovascular Medicine , (2005– present )
• Clinical Instructor & Staff Physician, Stanford Division of Cardiovascular Medicine , (1999– 2005 )
• Cardiology Fellow, Stanford Division of Cardiovascular Medicine , (1994– 1999 )

Honors and Awards

• Young Investigator Award, Finalist, American College of Cardiology (Senior Author) (2005)
• Young Investigator Award, Finalist, American College of Cardiology (Senior Author) (2004)
• Teaching Award, Stanford University School of Medicine (2004)
• Glaxo Smith Kline Scholar, American Federation of Medical Research (2003)
• Career Development Award, National Institute of Health (2000)
• Edwin L Alderman Award for Excellence in Research, Stanford Cardiovascular Medicine (1999)
• Young Investigator Award, American College of Cardiology (1998)
• Physiology & Pharmacology Research Award, Stanford Cardiovascular Medicine (1997)
• Soloman's Scholarship, UCLA Dept of Medicine (1993)
• Cum Laude, Yale University School of Medicine (1989)
• University Honors, Stanford Dept of Biological Sciences (1984)
• University Honors, Stanford Dept of East Asian Studies (1984)

Professional Education

• Board Certification: Cardiovascular Disease, American Board of Internal Medicine (1999)
• SUMC - Graduate Medical Education (1998) CA
• UCLA Medical Center (1993) CA
• UCLA - School of Medicine (1990) CA
• Yale University School of Medicine-Graduate (1989) CT
• Resident, UCLA Department of Medicine Internal Medicine (1993)
• MD, Yale University MD, Cum Laude (1989)
• MA, Stanford University East Asian Studies (1984)
• BAS, Stanford University Biology and East Asian Studies (1984)

Postdoctoral Advisees

• Jaehoon Chung, Annett Hahn-Windgassen, Ildiko Toma, I-Ning Wang

Community & International Work

• Editor, Journal of Cardiovascular Magnetic Resonance More »
• Member, American Heart Association, National Grant Study Committee More »
• Member, American Heart Association, Western Regional Grant Study Committee More »
• Board Member, National Center for Space Biological Technologies (NASA) More »
• Language Background More »

Research Interests

Dr. Yang's research interest focuses on the comprehensive diagnosis of ischemic heart disease using cardiac MRI. Specifically, he is using novel MR imaging sequences that enable rapid and integrated imaging of the coronary arteries as well as assessment of LV function, cardiac perfusion, and myocardial viability. By combining the chemical sensitivity of nuclear magnetic resonance with high spatial and temporal resolution, a wide range of biological events spanning from molecular to physiologic processes can be characterized. Dr. Yang's laboratory is implementing such innovative approach to in vivo imaging of stem cell biology and of the effects of cell therapy on the injured myocardium. Dr. Yang's research is supported by a prestigious K23 and R01 awards from the National Institutes of Health.

Publications

• Comparison of optical bioluminescence reporter gene and superparamagnetic iron oxide MR contrast agent as cell markers for noninvasive imaging of cardiac cell transplantation. Chen IY,  Greve JM, Gheysens O, Willmann JK, Rodriguez-Porcel M, Chu P, Sheikh AY, Faranesh AZ, Paulmurugan R, Yang PC, Wu JC, Gambhir SS.  Mol Imaging Biol.  2009 May-Jun; 11 (3): 178-87
• Magnetic resonance imaging of human embryonic stem cells. Chung J,  Yamada M, Yang PC.  Curr Protoc Stem Cell Biol.  2009; Chapter 5 Unit 5A.3
• Manganese-guided cellular MRI of human embryonic stem cell and human bone marrow stromal cell viability. Yamada M,  Gurney PT, Chung J, Kundu P, Drukker M, Smith AK, Weissman IL, Nishimura D, Robbins RC, Yang PC.  Magn Reson Med.  2009; 62 (4): 1047-54
• Comparison of reporter gene and iron particle labeling for tracking fate of human embryonic stem cells and differentiated endothelial cells in living subjects. Li Z,  Suzuki Y, Huang M, Cao F, Xie X, Connolly AJ, Yang PC, Wu JC.  Stem Cells.  2008; 26 (4): 864-73
• In vivo serial evaluation of superparamagnetic iron-oxide labeled stem cells by off-resonance positive contrast. Suzuki Y,  Cunningham CH, Noguchi K, Chen IY, Weissman IL, Yeung AC, Robbins RC, Yang PC.  Magn Reson Med.  2008; 60 (6): 1269-75
• Quantitative characterization of myocardial infarction by cardiovascular magnetic resonance predicts future cardiovascular events in patients with ischemic cardiomyopathy. Yokota H,  Heidary S, Katikireddy CK, Nguyen P, Pauly JM, McConnell MV, Yang PC.  J Cardiovasc Magn Reson.  2008; 10 (1): 17
• Multimodal evaluation of in vivo magnetic resonance imaging of myocardial restoration by mouse embryonic stem cells. Hendry SL,  van der Bogt KE, Sheikh AY, Arai T, Dylla SJ, Drukker M, McConnell MV, Kutschka I, Hoyt G, Cao F, Weissman IL, Connolly AJ, Pelletier MP, Wu JC, Robbins RC, Yang PC.  J Thorac Cardiovasc Surg.  2008; 136 (4): 1028-1037.e1
• Cardiovascular MRI for stem cell therapy. Suzuki Y,  Yeung AC, Yang PC.  Curr Cardiol Rep.  2007; 9 (1): 45-50
• Magnetic resonance imaging of progressive cardiomyopathic changes in the db/db mouse. Yue P,  Arai T, Terashima M, Sheikh AY, Cao F, Charo D, Hoyt G, Robbins RC, Ashley EA, Wu J, Yang PC, Tsao PS.  Am J Physiol Heart Circ Physiol.  2007; 292 (5): H2106-18
• In vitro comparison of the biological effects of three transfection methods for magnetically labeling mouse embryonic stem cells with ferumoxides. Suzuki Y,  Zhang S, Kundu P, Yeung AC, Robbins RC, Yang PC.  Magn Reson Med.  2007; 57 (6): 1173-9
• Collagen matrices enhance survival of transplanted cardiomyoblasts and contribute to functional improvement of ischemic rat hearts. Kutschka I,  Chen IY, Kofidis T, Arai T, von Degenfeld G, Sheikh AY, Hendry SL, Pearl J, Hoyt G, Sista R, Yang PC, Blau HM, Gambhir SS, Robbins RC.  Circulation.  2006; 114 (1 Suppl): I167-73
• Indirect magnetic resonance lymphangiography to assess lymphatic function in experimental murine lymphedema. Pan D,  Suzuki Y, Yang PC, Rockson SG.  Lymphat Res Biol.  2006; 4 (4): 211-6
• FeCo/graphitic-shell nanocrystals as advanced magnetic-resonance-imaging and near-infrared agents. Seo WS,  Lee JH, Sun X, Suzuki Y, Mann D, Liu Z, Terashima M, Yang PC, McConnell MV, Nishimura DG, Dai H.  Nat Mater.  2006; 5 (12): 971-6
• Peri-infarct ischemia determined by cardiovascular magnetic resonance evaluation of myocardial viability and stress perfusion predicts future cardiovascular events in patients with severe ischemic cardiomyopathy. Tsukiji M,  Nguyen P, Narayan G, Hellinger J, Chan F, Herfkens R, Pauly JM, McConnell MV, Yang PC.  J Cardiovasc Magn Reson.  2006; 8 (6): 773-9
• Real-time color-flow CMR in adults with congenital heart disease. de la Pena E,  Nguyen PK, Nayak KS, Yang PC, Rosenthal DN, Hu BS, Pauly JM, McConnell MV.  J Cardiovasc Magn Reson.  2006; 8 (6): 809-15
• Images in cardiovascular medicine. Cardiac magnetic resonance imaging for myocarditis: effective use in medical decision making. Fenster BE,  Chan FP, Valentine HA, Yang E, McConnell MV, Berry GJ, Yang PC.  Circulation.  2006; 113 (22): e842-3
• Dual in vivo magnetic resonance evaluation of magnetically labeled mouse embryonic stem cells and cardiac function at 1.5 t. Arai T,  Kofidis T, Bulte JW, de Bruin J, Venook RD, Berry GJ, Mcconnell MV, Quertermous T, Robbins RC, Yang PC.  Magn Reson Med.  2006; 55 (1): 203-9
• Noninvasive assessment of coronary vasodilation using magnetic resonance angiography. Terashima M,  Meyer CH, Keeffe BG, Putz EJ, de la Pena-Almaguer E, Yang PC, Hu BS, Nishimura DG, McConnell MV.  J Am Coll Cardiol.  2005; 45 (1): 104-10
• High-resolution real-time spiral MRI for guiding vascular interventions in a rabbit model at 1.5 T. Terashima M,  Hyon M, de la Pena-Almaguer E, Yang PC, Hu BS, Nayak KS, Pauly JM, McConnell MV.  J Magn Reson Imaging.  2005; 22 (5): 687-90
• Positive contrast magnetic resonance imaging of cells labeled with magnetic nanoparticles. Cunningham CH,  Arai T, Yang PC, McConnell MV, Pauly JM, Conolly SM.  Magn Reson Med.  2005; 53 (5): 999-1005
• Early diagnosis of hemochromatosis-related cardiomyopathy with magnetic resonance imaging. Ptaszek LM,  Price ET, Hu MY, Yang PC.  J Cardiovasc Magn Reson.  2005; 7 (4): 689-92
• Dynamic real-time architecture in magnetic resonance coronary angiography--a prospective clinical trial. Yang PC,  Santos JM, Nguyen PK, Scott GC, Engvall J, McConnell MV, Wright GA, Nishimura DG, Pauly JM, Hu BS.  J Cardiovasc Magn Reson.  2004; 6 (4): 885-94
• Spiral magnetic resonance coronary angiography--direct comparison of 1.5 Tesla vs. 3 Tesla. Yang PC,  Nguyen P, Shimakawa A, Brittain J, Pauly J, Nishimura D, Hu B, McConnell M.  J Cardiovasc Magn Reson.  2004; 6 (4): 877-84
• A visual approach for the accurate determination of echocardiographic left ventricular ejection fraction by medical students. Hope MD,  de la Pena E, Yang PC, Liang DH, McConnell MV, Rosenthal DN.  J Am Soc Echocardiogr.  2003; 16 (8): 824-31
• Spiral magnetic resonance coronary angiography with rapid real-time localization. Yang PC,  Meyer CH, Terashima M, Kaji S, McConnell MV, Macovski A, Pauly JM, Nishimura DG, Hu BS.  J Am Coll Cardiol.  2003; 41 (7): 1134-41
• Magnetic resonance coronary angiography. Yang PC,  McConnell MV, Nishimura DG, Hu BS.  Curr Cardiol Rep.  2003; 5 (1): 55-62
• Real-time interactive coronary MRA. Nayak KS,  Pauly JM, Yang PC, Hu BS, Meyer CH, Nishimura DG.  Magn Reson Med.  2001; 46 (3): 430-5
• Rapid evaluation of left ventricular volume and mass without breath-holding using real-time interactive cardiac magnetic resonance imaging system. Kaji S,  Yang PC, Kerr AB, Tang WH, Meyer CH, Macovski A, Pauly JM, Nishimura DG, Hu BS.  J Am Coll Cardiol.  2001; 38 (2): 527-33
• New real-time interactive cardiac magnetic resonance imaging system complements echocardiography. Yang PC,  Kerr AB, Liu AC, Liang DH, Hardy C, Meyer CH, Macovski A, Pauly JM, Hu BS.  J Am Coll Cardiol.  1998; 32 (7): 2049-56