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Key Documents

Dennis Carter

Professor, Mechanical Engineering
Member, Bio-X

Contact Information

Academic Offices

Personal Information
Email dcarter@stanford.edu Tel (650) 723-4784

Administrative Appointments

Associate Chair for Graduate Studies, Bioengineering , (2004– present )

Professional Education

Ph.D., Stanford University Biomedical Engineering (1976)
M.S.E., Stanford University Bioengineering (1973)
B.S., University of Michigan Aerospace Engineering (1971)

Graduate & Fellowship Program Affiliations

Research Interests

Professor Carter studies the influence of mechanical loading upon the growth, development, regeneration, and aging of skeletal tissues. Basic information from such studies is used to understand skeletal diseases and treatments. He has served as President of the Orthopaedic Research Society and is a Fellow of the American Institute for Medical and Biological Engineering.

Publications

The pathogenesis of osteoarthritis in cerebral palsy. Carter DR, Tse B. Dev Med Child Neurol. 2009; 51 Suppl 4 79-83
An approach to quantifying bone overloading and hypertrophy with applications to multiple experimental studies. Chen JC, Beaupré GS, Carter DR. Bone. 2009;
A new software tool (VA-BATTS) to calculate bending, axial, torsional and transverse shear stresses within bone cross sections having inhomogeneous material properties. Kourtis LC, Carter DR, Kesari H, Beaupre GS. Comput Methods Biomech Biomed Engin. 2008; 11 (5): 463-76
Meniscectomy alters the dynamic deformational behavior and cumulative strain of tibial articular cartilage in knee joints subjected to cyclic loads. Song Y, Greve JM, Carter DR, Giori NJ. Osteoarthritis Cartilage. 2008; 16 (12): 1545-54
Hydrostatic pressure enhances chondrogenic differentiation of human bone marrow stromal cells in osteochondrogenic medium. Wagner DR, Lindsey DP, Li KW, Tummala P, Chandran SE, Smith RL, Longaker MT, Carter DR, Beaupre GS. Ann Biomed Eng. 2008; 36 (5): 813-20
Rapid growth of cartilage rudiments may generate perichondrial structures by mechanical induction. Henderson JH, de la Fuente L, Romero D, Colnot CI, Huang S, Carter DR, Helms JA. Biomech Model Mechanobiol. 2007; 6 (1-2): 127-37
Benefit of single-leaf resection for horizontal meniscus tear. Haemer JM, Wang MJ, Carter DR, Giori NJ. Clin Orthop Relat Res. 2007; 457 194-202
Effects of hydrostatic pressure and transforming growth factor-beta 3 on adult human mesenchymal stem cell chondrogenesis in vitro. Miyanishi K, Trindade MC, Lindsey DP, Beaupré GS, Carter DR, Goodman SB, Schurman DJ, Smith RL. Tissue Eng. 2006; 12 (6): 1419-28
Dose- and time-dependent effects of cyclic hydrostatic pressure on transforming growth factor-beta3-induced chondrogenesis by adult human mesenchymal stem cells in vitro. Miyanishi K, Trindade MC, Lindsey DP, Beaupré GS, Carter DR, Goodman SB, Schurman DJ, Smith RL. Tissue Eng. 2006; 12 (8): 2253-62
Relationships between tissue dilatation and differentiation in distraction osteogenesis. Morgan EF, Longaker MT, Carter DR. Matrix Biol. 2006; 25 (2): 94-103
Articular cartilage MR imaging and thickness mapping of a loaded knee joint before and after meniscectomy. Song Y, Greve JM, Carter DR, Koo S, Giori NJ. Osteoarthritis Cartilage. 2006; 14 (8): 728-37
Dose- and Time-Dependent Effects of Cyclic Hydrostatic Pressure on Transforming Growth Factor-beta3-Induced Chondrogenesis by Adult Human Mesenchymal Stem Cells in Vitro. Miyanishi K, Trindade MC, Lindsey DP, Beaupré GS, Carter DR, Goodman SB, Schurman DJ, Smith RL. Tissue Eng. 2006;
Age-dependent properties and quasi-static strain in the rat sagittal suture. Henderson JH, Chang LY, Song HM, Longaker MT, Carter DR. J Biomech. 2005; 38 (11): 2294-301
Mechanobiology of mandibular distraction osteogenesis: finite element analyses with a rat model. Loboa EG, Fang TD, Parker DW, Warren SM, Fong KD, Longaker MT, Carter DR. J Orthop Res. 2005; 23 (3): 663-70
Age-dependent residual tensile strains are present in the dura mater of rats. Henderson JH, Nacamuli RP, Zhao B, Longaker MT, Carter DR. J R Soc Interface. 2005; 2 (3): 159-67
New QCT analysis approach shows the importance of fall orientation on femoral neck strength. Carpenter RD, Beaupré GS, Lang TF, Orwoll ES, Carter DR. J Bone Miner Res. 2005; 20 (9): 1533-42
Mechanobiological predictions of growth front morphology in developmental hip dysplasia. Shefelbine SJ, Carter DR. J Orthop Res. 2004; 22 (2): 346-52
Mechanobiological predictions of femoral anteversion in cerebral palsy. Shefelbine SJ, Carter DR. Ann Biomed Eng. 2004; 32 (2): 297-305
Mechanobiology of mandibular distraction osteogenesis: experimental analyses with a rat model. Loboa EG, Fang TD, Warren SM, Lindsey DP, Fong KD, Longaker MT, Carter DR. Bone. 2004; 34 (2): 336-43
Sutural bone deposition rate and strain magnitude during cranial development. Henderson JH, Longaker MT, Carter DR. Bone. 2004; 34 (2): 271-80
Pressure and shear differentially alter human articular chondrocyte metabolism: a review. Smith RL, Carter DR, Schurman DJ. Clin Orthop Relat Res. 2004; (427 Suppl): S89-95
The mechanobiology of articular cartilage development and degeneration. Carter DR, Beaupré GS, Wong M, Smith RL, Andriacchi TP, Schurman DJ. Clin Orthop Relat Res. 2004; (427 Suppl): S69-77
Mechanobiology of soft skeletal tissue differentiation--a computational approach of a fiber-reinforced poroelastic model based on homogeneous and isotropic simplifications. Loboa EG, Wren TA, Beaupré GS, Carter DR. Biomech Model Mechanobiol. 2003; 2 (2): 83-96
Modelling cartilage mechanobiology. Carter DR, Wong M. Philos Trans R Soc Lond B Biol Sci. 2003; 358 (1437): 1461-71
Mechanical strain affects dura mater biological processes: implications for immature calvarial healing. Fong KD, Warren SM, Loboa EG, Henderson JH, Fang TD, Cowan CM, Carter DR, Longaker MT. Plast Reconstr Surg. 2003; 112 (5): 1312-27
Equibiaxial tensile strain affects calvarial osteoblast biology. Fong KD, Nacamuli RP, Loboa EG, Henderson JH, Fang TD, Song HM, Cowan CM, Warren SM, Carter DR, Longaker MT. J Craniofac Surg. 2003; 14 (3): 348-55
Mechanical induction in limb morphogenesis: the role of growth-generated strains and pressures. Henderson JH, Carter DR. Bone. 2002; 31 (6): 645-53
Failure and fatigue characteristics of adhesive athletic tape. Bragg RW, Macmahon JM, Overom EK, Yerby SA, Matheson GO, Carter DR, Andriacchi TP. Med Sci Sports Exerc. 2002; 34 (3): 403-10
Development of the femoral bicondylar angle in hominid bipedalism. Shefelbine SJ, Tardieu C, Carter DR. Bone. 2002; 30 (5): 765-70
Mechanobiology of initial pseudarthrosis formation with oblique fractures. Loboa EG, Beaupré GS, Carter DR. J Orthop Res. 2001; 19 (6): 1067-72
Mechanical properties of the human achilles tendon. Wren TA, Yerby SA, Beaupré GS, Carter DR. Clin Biomech (Bristol, Avon). 2001; 16 (3): 245-51
A model of mechanobiologic and metabolic influences on bone adaptation. Hernandez CJ, Beaupré GS, Carter DR. J Rehabil Res Dev. 2000 Mar-Apr; 37 (2): 235-44
Mechanobiology of tendon adaptation to compressive loading through fibrocartilaginous metaplasia. Wren TA, Beaupré GS, Carter DR. J Rehabil Res Dev. 2000 Mar-Apr; 37 (2): 135-43
Mechanobiology in the development, maintenance, and degeneration of articular cartilage. Beaupré GS, Stevens SS, Carter DR. J Rehabil Res Dev. 2000 Mar-Apr; 37 (2): 145-51
Tendon and ligament adaptation to exercise, immobilization, and remobilization. Wren TA, Beaupré GS, Carter DR. J Rehabil Res Dev. 2000 Mar-Apr; 37 (2): 217-24
Calcaneal loading during walking and running. Giddings VL, Beaupré GS, Whalen RT, Carter DR. Med Sci Sports Exerc. 2000; 32 (3): 627-34
Coincident development of sesamoid bones and clues to their evolution. Sarin VK, Erickson GM, Giori NJ, Bergman AG, Carter DR. Anat Rec. 1999; 257 (5): 174-80
Mechanically modulated cartilage growth may regulate joint surface morphogenesis. Heegaard JH, Beaupré GS, Carter DR. J Orthop Res. 1999; 17 (4): 509-17
DXA-derived section modulus and bone mineral content predict long-bone torsional strength. Sarin VK, Loboa Polefka EG, Beaupré GS, Kiratli BJ, Carter DR, van der Meulen MC. Acta Orthop Scand. 1999; 70 (1): 71-6
A model for loading-dependent growth, development, and adaptation of tendons and ligaments. Wren TA, Beaupré GS, Carter DR. J Biomech. 1998; 31 (2): 107-14
Mechanobiology of skeletal regeneration. Carter DR, Beaupré GS, Giori NJ, Helms JA. Clin Orthop Relat Res. 1998; (355 Suppl): S41-55
Correspondence between theoretical models and dual energy x-ray absorptiometry measurements of femoral cross-sectional growth during adolescence. van der Meulen MC, Marcus R, Bachrach LK, Carter DR. J Orthop Res. 1997; 15 (3): 473-6
Body mass is the primary determinant of midfemoral bone acquisition during adolescent growth. Moro M, van der Meulen MC, Kiratli BJ, Marcus R, Bachrach LK, Carter DR. Bone. 1996; 19 (5): 519-26
Mechanical factors in bone growth and development. Carter DR, Van Der Meulen MC, Beaupré GS. Bone. 1996; 18 (1 Suppl): 5S-10S
In vitro stimulation of articular chondrocyte mRNA and extracellular matrix synthesis by hydrostatic pressure. Smith RL, Rusk SF, Ellison BE, Wessells P, Tsuchiya K, Carter DR, Caler WE, Sandell LJ, Schurman DJ. J Orthop Res. 1996; 14 (1): 53-60
Mechanical influences on tissue differentiation at bone-cement interfaces. Giori NJ, Ryd L, Carter DR. J Arthroplasty. 1995; 10 (4): 514-22
Bone strain gage data and theoretical models of functional adaptation. Miki? B, Carter DR. J Biomech. 1995; 28 (4): 465-9
Mechanobiologic influences in long bone cross-sectional growth. van der Meulen MC, Beaupré GS, Carter DR. Bone. 1993 Jul-Aug; 14 (4): 635-42
Cellular shape and pressure may mediate mechanical control of tissue composition in tendons. Giori NJ, Beaupré GS, Carter DR. J Orthop Res. 1993; 11 (4): 581-91
Computer simulations of stress-related bone remodeling around noncemented acetabular components. Levenston ME, Beaupré GS, Schurman DJ, Carter DR. J Arthroplasty. 1993; 8 (6): 595-605
Rabbit knee immobilization: bone remodeling precedes cartilage degradation. Smith RL, Thomas KD, Schurman DJ, Carter DR, Wong M, van der Meulen MC. J Orthop Res. 1992; 10 (1): 88-95
Skeletal development and bone functional adaptation. Carter DR, Orr TE. J Bone Miner Res. 1992; 7 Suppl 2 S389-95
New approaches for interpreting projected bone densitometry data. Carter DR, Bouxsein ML, Marcus R. J Bone Miner Res. 1992; 7 (2): 137-45
In vitro study of initial stability of a conical collared femoral component. Fischer KJ, Carter DR, Maloney WJ. J Arthroplasty. 1992; 7 Suppl 389-95
Computational methods for analyzing the structure of cancellous bone in planar sections. Kuo AD, Carter DR. J Orthop Res. 1991; 9 (6): 918-31
Musculoskeletal ontogeny, phylogeny, and functional adaptation. Carter DR, Wong M, Orr TE. J Biomech. 1991; 24 Suppl 1 3-16
Effects of fluoride treatment on bone strength. Carter DR, Beaupré GS. J Bone Miner Res. 1990; 5 Suppl 1 S177-84
A theoretical model of endochondral ossification and bone architectural construction in long bone ontogeny. Wong M, Carter DR. Anat Embryol (Berl). 1990; 181 (6): 523-32
Bone creep-fatigue damage accumulation. Caler WE, Carter DR. J Biomech. 1989; 22 (6-7): 625-35
Role of mechanical loading in the progressive ossification of a fracture callus. Blenman PR, Carter DR, Beaupré GS. J Orthop Res. 1989; 7 (3): 398-407
Correlations between mechanical stress history and tissue differentiation in initial fracture healing. Carter DR, Blenman PR, Beaupré GS. J Orthop Res. 1988; 6 (5): 736-48
Relation of coxarthrosis to stresses and morphogenesis. A finite element analysis. Carter DR, Rapperport DJ, Fyhrie DP, Schurman DJ. Acta Orthop Scand. 1987; 58 (6): 611-9
Acetabular lucent lines and mechanical stress in total hip arthroplasty. Goodman SB, Carter DR. J Arthroplasty. 1987; 2 (3): 219-24
Trabecular bone density and loading history: regulation of connective tissue biology by mechanical energy. Carter DR, Fyhrie DP, Whalen RT. J Biomech. 1987; 20 (8): 785-94
Mechanical loading history and skeletal biology. Carter DR, J Biomech. 1987; 20 (11-12): 1095-109