Maarten Lansberg, M.D., Ph.D.

Clinical Focus

• Neurology
• Stroke
• Cerebrovascular Disease

Professional Education

• Board Certification: Neurology, American Board of Psychiatry and Neurology (2004)
• Stanford Hospital & Clinics (2004) CA USA
• UCSF Medical Center (2003) CA
• Greater Baltimore Medical Ctr (2000) MD
• University of Utrecht (1997) The Netherlands
• MS, Stanford University Epidemiology (2008)
• Ph.D., Univ of Utrecht, The Netherlands Diffusion-Weighted MRI in Stroke (2002)
• M.D., Univ of Utrecht, The Netherlands (1997)

Graduate & Fellowship Program Affiliations

• Neurology and Neurol Sciences

Web Site Links

• Stanford Stroke Center

Industry Relationships

Stanford is committed to ethical and transparent interactions with our industry partners. It is our policy to disclose payments of $5,000 or more, equity valued at $5,000 or more in a publicly traded company, or any equity in a privately held company, to physicians and scientists employed by Stanford University from companies or other commercial entities with which they interact as part of their professional activities. 

• Consulting: Otjen, van Ert & Weir

Research Interests

1. Imaging of Cerebral Perfusion with MRI and Xenon CT
2. Determining selection criteria that identify stroke patients who are most likely to benefit from iv tPA
3. Combining iv tPA with intraarterial mechanical thrombectomy for acute stroke
4. Detection of Atrial Fibrillation in patients with stroke and TIA using long term ambulatory cardiac monitoring
5. Prognosis of critically ill neurological patients

Clinical Trials

• The Insulin Resistance Intervention after Stroke Trial (IRIS) Recruiting
• Diagnostic Utility of MRI in Intracerebral Hemorrhage Recruiting
• Minimally Invasive Surgery Plus rt-PA for ICH Evacuation (MISTIE) Recruiting

Publications

• Improving dynamic susceptibility contrast MRI measurement of quantitative cerebral blood flow using corrections for partial volume and nonlinear contrast relaxivity: A xenon computed tomographic comparative study. Zaharchuk G,  Bammer R, Straka M, Newbould RD, Rosenberg J, Olivot JM, Mlynash M, Lansberg MG, Schwartz NE, Marks MM, Albers GW, Moseley ME.  J Magn Reson Imaging.  2009; 30 (4): 743-52
• Favorable Outcome From A Locked-In State Despite Extensive Pontine Infarction By MRI. Samaniego EA,  Lansberg MG, Degeorgia M, Venkatasubramanian C, Wijman CA.  Neurocrit Care.  2009;
• Cost-effectiveness analysis of mechanical thrombectomy in acute ischemic stroke. Patil CG,  Long EF, Lansberg MG.  J Neurosurg.  2009; 110 (3): 508-13
• Yield of combined perfusion and diffusion MR imaging in hemispheric TIA. Mlynash M,  Olivot JM, Tong DC, Lansberg MG, Eyngorn I, Kemp S, Moseley ME, Albers GW.  Neurology.  2009; 72 (13): 1127-33
• Optimal Tmax threshold for predicting penumbral tissue in acute stroke. Olivot JM,  Mlynash M, Thijs VN, Kemp S, Lansberg MG, Wechsler L, Bammer R, Marks MP, Albers GW.  Stroke.  2009; 40 (2): 469-75
• Geography, structure, and evolution of diffusion and perfusion lesions in Diffusion and perfusion imaging Evaluation For Understanding Stroke Evolution (DEFUSE). Olivot JM,  Mlynash M, Thijs VN, Purushotham A, Kemp S, Lansberg MG, Wechsler L, Gold GE, Bammer R, Marks MP, Albers GW.  Stroke.  2009; 40 (10): 3245-51
• Efficacy and safety of tissue plasminogen activator 3 to 4.5 hours after acute ischemic stroke: a metaanalysis. Lansberg MG,  Bluhmki E, Thijs VN.  Stroke.  2009; 40 (7): 2438-41
• Treatment time-specific number needed to treat estimates for tissue plasminogen activator therapy in acute stroke based on shifts over the entire range of the modified Rankin Scale. Lansberg MG,  Schrooten M, Bluhmki E, Thijs VN, Saver JL.  Stroke.  2009; 40 (6): 2079-84
• Perfusion MRI (Tmax and MTT) correlation with xenon CT cerebral blood flow in stroke patients. Olivot JM,  Mlynash M, Zaharchuk G, Straka M, Bammer R, Schwartz N, Lansberg MG, Moseley ME, Albers GW.  Neurology.  2009; 72 (13): 1140-5
• Relationships between cerebral perfusion and reversibility of acute diffusion lesions in DEFUSE: insights from RADAR. Olivot JM,  Mlynash M, Thijs VN, Purushotham A, Kemp S, Lansberg MG, Wechsler L, Bammer R, Marks MP, Albers GW.  Stroke.  2009; 40 (5): 1692-7
• Concurrent presentation of perimesencephalic subarachnoid hemorrhage and ischemic stroke. Lansberg MG,  J Stroke Cerebrovasc Dis.  2008 Jul-Aug; 17 (4): 248-50
• Relationships between infarct growth, clinical outcome, and early recanalization in diffusion and perfusion imaging for understanding stroke evolution (DEFUSE). Olivot JM,  Mlynash M, Thijs VN, Kemp S, Lansberg MG, Wechsler L, Schlaug G, Bammer R, Marks MP, Albers GW.  Stroke.  2008; 39 (8): 2257-63
• The MRA-DWI mismatch identifies patients with stroke who are likely to benefit from reperfusion. Lansberg MG,  Thijs VN, Bammer R, Olivot JM, Marks MP, Wechsler LR, Kemp S, Albers GW.  Stroke.  2008; 39 (9): 2491-6
• Patients with acute stroke treated with intravenous tPA 3-6 hours after stroke onset: correlations between MR angiography findings and perfusion- and diffusion-weighted imaging in the DEFUSE study. Marks MP,  Olivot JM, Kemp S, Lansberg MG, Bammer R, Wechsler LR, Albers GW, Thijs V.  Radiology.  2008; 249 (2): 614-23
• Delirium following abrupt discontinuation of fluoxetine. Blum D,  Maldonado J, Meyer E, Lansberg M.  Clin Neurol Neurosurg.  2008; 110 (1): 69-70
• Evaluation of the clinical-diffusion and perfusion-diffusion mismatch models in DEFUSE. Lansberg MG,  Thijs VN, Hamilton S, Schlaug G, Bammer R, Kemp S, Albers GW.  Stroke.  2007; 38 (6): 1826-30
• Symptomatic intracerebral hemorrhage following thrombolytic therapy for acute ischemic stroke: a review of the risk factors. Lansberg MG,  Albers GW, Wijman CA.  Cerebrovasc Dis.  2007; 24 (1): 1-10
• Risk factors of symptomatic intracerebral hemorrhage after tPA therapy for acute stroke. Lansberg MG,  Thijs VN, Bammer R, Kemp S, Wijman CA, Marks MP, Albers GW.  Stroke.  2007; 38 (8): 2275-8
• Magnetic resonance imaging profiles predict clinical response to early reperfusion: the diffusion and perfusion imaging evaluation for understanding stroke evolution (DEFUSE) study. Albers GW,  Thijs VN, Wechsler L, Kemp S, Schlaug G, Skalabrin E, Bammer R, Kakuda W, Lansberg MG, Shuaib A, Coplin W, Hamilton S, Moseley M, Marks MP.  Ann Neurol.  2006; 60 (5): 508-17
• MRI characteristics of cerebral air embolism from a venous source. Caulfield AF,  Lansberg MG, Marks MP, Albers GW, Wijman CA.  Neurology.  2006; 66 (6): 945-6
• "Paradoxical" transtentorial herniation due to CSF drainage in the presence of a hemicraniectomy. Fields JD,  Lansberg MG, Skirboll SL, Kurien PA, Wijman CA.  Neurology.  2006; 67 (8): 1513-4
• Mechanical thrombectomy following intravenous thrombolysis in the treatment of acute stroke. Lansberg MG,  Fields JD, Albers GW, Jayaraman MV, Do HM, Marks MP.  Arch Neurol.  2005; 62 (11): 1763-5
• Clinical importance of microbleeds in patients receiving IV thrombolysis. Kakuda W,  Thijs VN, Lansberg MG, Bammer R, Wechsler L, Kemp S, Moseley ME, Marks MP, Albers GW.  Neurology.  2005; 65 (8): 1175-8
• Evolution of apparent diffusion coefficient, diffusion-weighted, and T2-weighted signal intensity of acute stroke. Lansberg MG,  Thijs VN, O'Brien MW, Ali JO, de Crespigny AJ, Tong DC, Moseley ME, Albers GW.  AJNR Am J Neuroradiol.  2001; 22 (4): 637-44
• Evolution of cerebral infarct volume assessed by diffusion-weighted magnetic resonance imaging. Lansberg MG,  O'Brien MW, Tong DC, Moseley ME, Albers GW.  Arch Neurol.  2001; 58 (4): 613-7
• Comparison of diffusion-weighted MRI and CT in acute stroke. Lansberg MG,  Albers GW, Beaulieu C, Marks MP.  Neurology.  2000; 54 (8): 1557-61
• Yield of diffusion-weighted MRI for detection of potentially relevant findings in stroke patients. Albers GW,  Lansberg MG, Norbash AM, Tong DC, O'Brien MW, Woolfenden AR, Marks MP, Moseley ME.  Neurology.  2000; 54 (8): 1562-7
• Is early ischemic lesion volume on diffusion-weighted imaging an independent predictor of stroke outcome? A multivariable analysis. Thijs VN,  Lansberg MG, Beaulieu C, Marks MP, Moseley ME, Albers GW.  Stroke.  2000; 31 (11): 2597-602
• Advantages of adding diffusion-weighted magnetic resonance imaging to conventional magnetic resonance imaging for evaluating acute stroke. Lansberg MG,  Norbash AM, Marks MP, Tong DC, Moseley ME, Albers GW.  Arch Neurol.  2000; 57 (9): 1311-6
• Headache with neurological deficits and CSF lymphocytosis: A transient ischemic attack mimic. Lansberg MG,  Woolfenden AR, Norbash AM, Smith DB, Albers GW.  J Stroke Cerebrovasc Dis.  1999 Jan-Feb; 8 (1): 42-4
• Intra-arterial rtPA treatment of stroke assessed by diffusion- and perfusion-weighted MRI. Lansberg MG,  Tong DC, Norbash AM, Yenari MA, Moseley ME.  Stroke.  1999; 30 (3): 678-80
• MRI abnormalities associated with partial status epilepticus. Lansberg MG,  O'Brien MW, Norbash AM, Moseley ME, Morrell M, Albers GW.  Neurology.  1999; 52 (5): 1021-7