Michael Greicius

Clinical Focus

• Behavioral Neurology
• Memory Disorders
• Neurology

Professional Education

• Board Certification: Neurology, American Board of Psychiatry and Neurology (2003)
• SUMC - Graduate Medical Education (2001) CA
• Brigham and Women's Hospital (2000) MA
• Massachusetts General Hospital (2000) MA
• Columbia Presbyterian Medical Center (1997) NY
• Columbia University (1996) NY

Postdoctoral Advisees

• Jessica Damoiseaux

Research Interests

Dr. Greicius' research involves the use of functional MRI in conjunction with other imaging modalities to detect and characterize neural networks in healthy adults and patients with neuropsychiatric disorders. The main research objective is to develop novel imaging biomarkers that will enhance the understanding, diagnosis, and treatment of disorders such as Alzheimer's disease, major depression, and schizophrenia.

Clinical Trials

• Effects of Growth Hormone on Cognition and Cerebral Metabolism in Adults Recruiting

Publications

• Neurodegenerative diseases target large-scale human brain networks. Seeley WW,  Crawford RK, Zhou J, Miller BL, Greicius MD.  Neuron.  2009; 62 (1): 42-52
• Greater than the sum of its parts: a review of studies combining structural connectivity and resting-state functional connectivity. Damoiseaux JS,  Greicius MD.  Brain Struct Funct.  2009; 213 (6): 525-33
• Resting-state functional connectivity reflects structural connectivity in the default mode network. Greicius MD,  Supekar K, Menon V, Dougherty RF.  Cereb Cortex.  2009; 19 (1): 72-8
• Episodic encephalopathy due to an occult spinal vascular malformation complicated by superficial siderosis. Gonella MC,  Fischbein NJ, Lane B, Shuer LM, Greicius MD.  Clin Neurol Neurosurg.  2009;
• Network analysis of intrinsic functional brain connectivity in Alzheimer's disease. Supekar K,  Menon V, Rubin D, Musen M, Greicius MD.  PLoS Comput Biol.  2008; 4 (6): e1000100
• Default-mode function and task-induced deactivation have overlapping brain substrates in children. Thomason ME,  Chang CE, Glover GH, Gabrieli JD, Greicius MD, Gotlib IH.  Neuroimage.  2008; 41 (4): 1493-503
• Persistent default-mode network connectivity during light sedation. Greicius MD,  Kiviniemi V, Tervonen O, Vainionpää V, Alahuhta S, Reiss AL, Menon V.  Hum Brain Mapp.  2008; 29 (7): 839-47
• Divergent social functioning in behavioral variant frontotemporal dementia and Alzheimer disease: reciprocal networks and neuronal evolution. Seeley WW,  Allman JM, Carlin DA, Crawford RK, Macedo MN, Greicius MD, Dearmond SJ, Miller BL.  Alzheimer Dis Assoc Disord.  2007 Oct-Dec; 21 (4): S50-7
• Resting-state functional connectivity in major depression: abnormally increased contributions from subgenual cingulate cortex and thalamus. Greicius MD,  Flores BH, Menon V, Glover GH, Solvason HB, Kenna H, Reiss AL, Schatzberg AF.  Biol Psychiatry.  2007; 62 (5): 429-37
• Dissociable intrinsic connectivity networks for salience processing and executive control. Seeley WW,  Menon V, Schatzberg AF, Keller J, Glover GH, Kenna H, Reiss AL, Greicius MD.  J Neurosci.  2007; 27 (9): 2349-56
• Non-fluent progressive aphasia, depression, and OCD in a woman with progressive supranuclear palsy: neuroanatomical and neuropathological correlations. Karnik NS,  D'Apuzzo M, Greicius M.  Neurocase.  2006; 12 (6): 332-8
• Default-mode network activity distinguishes Alzheimer's disease from healthy aging: evidence from functional MRI. Greicius MD,  Srivastava G, Reiss AL, Menon V.  Proc Natl Acad Sci U S A.  2004; 101 (13): 4637-42
• Reduced basal forebrain and hippocampal activation during memory encoding in girls with fragile X syndrome. Greicius MD,  Boyett-Anderson JM, Menon V, Reiss AL.  Neuroreport.  2004; 15 (10): 1579-83
• Default-mode activity during a passive sensory task: uncoupled from deactivation but impacting activation. Greicius MD,  Menon V.  J Cogn Neurosci.  2004; 16 (9): 1484-92
• Humor modulates the mesolimbic reward centers. Mobbs D,  Greicius MD, Abdel-Azim E, Menon V, Reiss AL.  Neuron.  2003; 40 (5): 1041-8
• Comparison of fMRI activation at 3 and 1.5 T during perceptual, cognitive, and affective processing. Krasnow B,  Tamm L, Greicius MD, Yang TT, Glover GH, Reiss AL, Menon V.  Neuroimage.  2003; 18 (4): 813-26
• Regional analysis of hippocampal activation during memory encoding and retrieval: fMRI study. Greicius MD,  Krasnow B, Boyett-Anderson JM, Eliez S, Schatzberg AF, Reiss AL, Menon V.  Hippocampus.  2003; 13 (1): 164-74
• Functional connectivity in the resting brain: a network analysis of the default mode hypothesis. Greicius MD,  Krasnow B, Reiss AL, Menon V.  Proc Natl Acad Sci U S A.  2003; 100 (1): 253-8
• Neuroimaging in developmental disorders. Greicius MD,  Curr Opin Neurol.  2003; 16 (2): 143-6
• Presenile dementia syndromes: an update on taxonomy and diagnosis. Greicius MD,  Geschwind MD, Miller BL.  J Neurol Neurosurg Psychiatry.  2002; 72 (6): 691-700