Michael V. McConnell, MD, MSEE

Clinical Focus

• Cardiovascular Disease

Administrative Appointments

• Co-Director, Noninvasive Imaging Section, Stanford Division of Cardiovascular Medicine, Stanford , (2007– present )
• Member, Molecular Imaging Program at Stanford (MIPS) Faculty, Stanford , (2003– present )
• Physician Representative, Stanford Pharmacy and Therapeutics Committee, Stanford , (2001– present )
• Director, Cardiovascular MRI Program, Stanford Division of Cardiovascular Medicine, Stanford , (2000– present )
• Associate Director, Stanford Cardiovascular Medicine Fellowship Program, Stanford , (2000– present )

Honors and Awards

• Research Scholarship/Aquitaine Region, Fulbright Foundation (2008)
• Diversity & Leadership Faculty Fellow, Stanford (2007)
• Department of Medicine Teaching Award, Stanford (2002)
• American Heart Association Clinician Scientist Award, Stanford (1996)
• NHLBI Individual National Research Service Award, Stanford (1994)
• Stanford Dean's Awards for Research, Excellence in Clinical Medicine, and Outstanding Teaching, Stanford (1990)
• Elected to Eta Kappa Nu, Tau Beta Pi (1982), and Sigma Xi (1984), MIT (1981)
• Doris Duke Clinical Scientist Award, Stanford (1999)
• Fellowship, Harvard/MIT Clinical Investigator Training Program, Harvard/MIT (1996)
• SCA&I Fellowship Award for Research in Cardiac Imaging, Bracco Diagnostics, Inc (1995)

Professional Education

• Brigham and Women's Hospital, Harvard Medical School (1996) MA
• Brigham and Women's Hospital, Harvard Medical School (1992) MA
• Brigham and Women's Hospital, Harvard Medical School (1991) MA
• M.M.Sc., Harvard Clinical Investigation (1998)
• Stanford University School of Medicine (1990) CA
• M.S., M.I.T. Electrical Engineering (1985)
• B.S., M.I.T. Electrical Engineering (1983)
• M.D., Stanford Medicine (1990)

Postdoctoral Advisees

• Catherine Dao, Apostolos Drolias, Toshiro Kitagawa, Hisanori Kosuge, Holden Wu

Graduate & Fellowship Program Affiliations

• Bioengineering
• Cardiovascular Medicine

Research Interests

Imaging cardiovascular disease, with a focus on coronary and vascular atherosclerosis and ischemic heart disease. Projects include cellular and structural characterization of atherosclerotic plaque by MRI, optical imaging (bioluminescence and fluorescence) of vascular inflammation, as well as noninvasive coronary angiography by MRI and MRI- guided cardiovascular interventions. Additional collaborative projects include real-time cardiac MRI and multi-modality imaging of cardiac stem cell transplantation.

Clinical Trials

• Abdominal Aortic Aneurysms: Simple Treatment or Prevention (AAA: STOP) Recruiting

Publications

• Analysis of in situ and ex vivo vascular endothelial growth factor receptor expression during experimental aortic aneurysm progression. Tedesco MM,  Terashima M, Blankenberg FG, Levashova Z, Spin JM, Backer MV, Backer JM, Sho M, Sho E, McConnell MV, Dalman RL.  Arterioscler Thromb Vasc Biol.  2009; 29 (10): 1452-7
• Society for Cardiovascular Magnetic Resonance guidelines for reporting cardiovascular magnetic resonance examinations. Hundley WG,  Bluemke D, Bogaert JG, Friedrich MG, Higgins CB, Lawson MA, McConnell MV, Raman SV, van Rossum AC, Flamm S, Kramer CM, Nagel E, Neubauer S.  J Cardiovasc Magn Reson.  2009; 11 (1): 5
• High-contrast in vivo visualization of microvessels using novel FeCo/GC magnetic nanocrystals. Lee JH,  Sherlock SP, Terashima M, Kosuge H, Suzuki Y, Goodwin A, Robinson J, Seo WS, Liu Z, Luong R, McConnell MV, Nishimura DG, Dai H.  Magn Reson Med.  2009;
• Images in clinical medicine. A swinging heart. Kapoor JR,  McConnell MV.  N Engl J Med.  2009; 361 (18): e37
• An unusual case of partial anomalous pulmonary venous drainage: utility of the cardiac MRI. Kapoor JR,  Katikireddy C, Rubin G, Schnittger I, McConnell MV.  Int J Cardiol.  2009; 133 (1): e35-6
• Noninvasive assessment of coronary vasodilation using cardiovascular magnetic resonance in patients at high risk for coronary artery disease. Nguyen PK,  Meyer C, Engvall J, Yang P, McConnell MV.  J Cardiovasc Magn Reson.  2008; 10 (1): 28
• A human ferritin iron oxide nano-composite magnetic resonance contrast agent. Uchida M,  Terashima M, Cunningham CH, Suzuki Y, Willits DA, Willis AF, Yang PC, Tsao PS, McConnell MV, Young MJ, Douglas T.  Magn Reson Med.  2008; 60 (5): 1073-81
• Multimodal evaluation of in vivo magnetic resonance imaging of myocardial restoration by mouse embryonic stem cells. Hendry SL,  van der Bogt KE, Sheikh AY, Arai T, Dylla SJ, Drukker M, McConnell MV, Kutschka I, Hoyt G, Cao F, Weissman IL, Connolly AJ, Pelletier MP, Wu JC, Robbins RC, Yang PC.  J Thorac Cardiovasc Surg.  2008; 136 (4): 1028-1037.e1
• Impaired coronary vasodilation by magnetic resonance angiography is associated with advanced coronary artery calcification. Terashima M,  Nguyen PK, Rubin GD, Iribarren C, Courtney BK, Go AS, Fortmann SP, McConnell MV.  JACC Cardiovasc Imaging.  2008; 1 (2): 167-73
• Quantitative characterization of myocardial infarction by cardiovascular magnetic resonance predicts future cardiovascular events in patients with ischemic cardiomyopathy. Yokota H,  Heidary S, Katikireddy CK, Nguyen P, Pauly JM, McConnell MV, Yang PC.  J Cardiovasc Magn Reson.  2008; 10 (1): 17
• Multicontrast black-blood MRI of carotid arteries: comparison between 1.5 and 3 tesla magnetic field strengths. Yarnykh VL,  Terashima M, Hayes CE, Shimakawa A, Takaya N, Nguyen PK, Brittain JH, McConnell MV, Yuan C.  J Magn Reson Imaging.  2006; 23 (5): 691-8
• Dual in vivo magnetic resonance evaluation of magnetically labeled mouse embryonic stem cells and cardiac function at 1.5 t. Arai T,  Kofidis T, Bulte JW, de Bruin J, Venook RD, Berry GJ, Mcconnell MV, Quertermous T, Robbins RC, Yang PC.  Magn Reson Med.  2006; 55 (1): 203-9
• Images in cardiovascular medicine. Cardiac magnetic resonance imaging for myocarditis: effective use in medical decision making. Fenster BE,  Chan FP, Valentine HA, Yang E, McConnell MV, Berry GJ, Yang PC.  Circulation.  2006; 113 (22): e842-3
• Real-time color-flow CMR in adults with congenital heart disease. de la Pena E,  Nguyen PK, Nayak KS, Yang PC, Rosenthal DN, Hu BS, Pauly JM, McConnell MV.  J Cardiovasc Magn Reson.  2006; 8 (6): 809-15
• Peri-infarct ischemia determined by cardiovascular magnetic resonance evaluation of myocardial viability and stress perfusion predicts future cardiovascular events in patients with severe ischemic cardiomyopathy. Tsukiji M,  Nguyen P, Narayan G, Hellinger J, Chan F, Herfkens R, Pauly JM, McConnell MV, Yang PC.  J Cardiovasc Magn Reson.  2006; 8 (6): 773-9
• FeCo/graphitic-shell nanocrystals as advanced magnetic-resonance-imaging and near-infrared agents. Seo WS,  Lee JH, Sun X, Suzuki Y, Mann D, Liu Z, Terashima M, Yang PC, McConnell MV, Nishimura DG, Dai H.  Nat Mater.  2006; 5 (12): 971-6
• High-resolution real-time spiral MRI for guiding vascular interventions in a rabbit model at 1.5 T. Terashima M,  Hyon M, de la Pena-Almaguer E, Yang PC, Hu BS, Nayak KS, Pauly JM, McConnell MV.  J Magn Reson Imaging.  2005; 22 (5): 687-90
• Positive contrast magnetic resonance imaging of cells labeled with magnetic nanoparticles. Cunningham CH,  Arai T, Yang PC, McConnell MV, Pauly JM, Conolly SM.  Magn Reson Med.  2005; 53 (5): 999-1005
• Noninvasive assessment of coronary vasodilation using magnetic resonance angiography. Terashima M,  Meyer CH, Keeffe BG, Putz EJ, de la Pena-Almaguer E, Yang PC, Hu BS, Nishimura DG, McConnell MV.  J Am Coll Cardiol.  2005; 45 (1): 104-10
• Spiral magnetic resonance coronary angiography--direct comparison of 1.5 Tesla vs. 3 Tesla. Yang PC,  Nguyen P, Shimakawa A, Brittain J, Pauly J, Nishimura D, Hu B, McConnell M.  J Cardiovasc Magn Reson.  2004; 6 (4): 877-84
• Dynamic real-time architecture in magnetic resonance coronary angiography--a prospective clinical trial. Yang PC,  Santos JM, Nguyen PK, Scott GC, Engvall J, McConnell MV, Wright GA, Nishimura DG, Pauly JM, Hu BS.  J Cardiovasc Magn Reson.  2004; 6 (4): 885-94
• Magnetic resonance coronary angiography. Yang PC,  McConnell MV, Nishimura DG, Hu BS.  Curr Cardiol Rep.  2003; 5 (1): 55-62
• A visual approach for the accurate determination of echocardiographic left ventricular ejection fraction by medical students. Hope MD,  de la Pena E, Yang PC, Liang DH, McConnell MV, Rosenthal DN.  J Am Soc Echocardiogr.  2003; 16 (8): 824-31
• Spiral magnetic resonance coronary angiography with rapid real-time localization. Yang PC,  Meyer CH, Terashima M, Kaji S, McConnell MV, Macovski A, Pauly JM, Nishimura DG, Hu BS.  J Am Coll Cardiol.  2003; 41 (7): 1134-41
• In vivo real-time intravascular MRI. Rivas PA,  Nayak KS, Scott GC, McConnell MV, Kerr AB, Nishimura DG, Pauly JM, Hu BS.  J Cardiovasc Magn Reson.  2002; 4 (2): 223-32
• Echocardiographic and magnetic resonance methods for diagnosing hibernating myocardium. Cho S,  McConnell MV.  Nucl Med Commun.  2002; 23 (4): 331-9
• The diagnosis of congenital coronary anomalies with magnetic resonance imaging. Danias PG,  Stuber M, McConnell MV, Manning WJ.  Coron Artery Dis.  2001; 12 (8): 621-6
• Clinical role of coronary magnetic resonance angiography in the diagnosis of anomalous coronary arteries. McConnell MV,  Stuber M, Manning WJ.  J Cardiovasc Magn Reson.  2000; 2 (3): 217-24
• Imaging techniques to predict cardiovascular risk. McConnell MV,  Curr Cardiol Rep.  2000; 2 (4): 300-7
• Contrast agent-enhanced, free-breathing, three-dimensional coronary magnetic resonance angiography. Stuber M,  Botnar RM, Danias PG, McConnell MV, Kissinger KV, Yucel EK, Manning WJ.  J Magn Reson Imaging.  1999; 10 (5): 790-9
• MRI of rabbit atherosclerosis in response to dietary cholesterol lowering. McConnell MV,  Aikawa M, Maier SE, Ganz P, Libby P, Lee RT.  Arterioscler Thromb Vasc Biol.  1999; 19 (8): 1956-9
• Recovery of regional right ventricular function after thrombolysis for pulmonary embolism. Nass N,  McConnell MV, Goldhaber SZ, Chyu S, Solomon SD.  Am J Cardiol.  1999; 83 (5): 804-6, A10
• Adaptive correction of imaging plane position in segmented k-space cine cardiac MRI. Chuang ML,  Chen MH, Khasgiwala VC, McConnell MV, Edelman RR, Manning WJ.  J Magn Reson Imaging.  1997 Sep-Oct; 7 (5): 811-4
• Comparison of respiratory suppression methods and navigator locations for MR coronary angiography. McConnell MV,  Khasgiwala VC, Savord BJ, Chen MH, Chuang ML, Edelman RR, Manning WJ.  AJR Am J Roentgenol.  1997; 168 (5): 1369-75
• Effects of a single, daily alcoholic beverage on lipid and hemostatic markers of cardiovascular risk. McConnell MV,  Vavouranakis I, Wu LL, Vaughan DE, Ridker PM.  Am J Cardiol.  1997; 80 (9): 1226-8
• Prospective navigator correction of image position for coronary MR angiography. Danias PG,  McConnell MV, Khasgiwala VC, Chuang ML, Edelman RR, Manning WJ.  Radiology.  1997; 203 (3): 733-6
• Prospective adaptive navigator correction for breath-hold MR coronary angiography. McConnell MV,  Khasgiwala VC, Savord BJ, Chen MH, Chuang ML, Edelman RR, Manning WJ.  Magn Reson Med.  1997; 37 (1): 148-52
• Regional right ventricular dysfunction detected by echocardiography in acute pulmonary embolism. McConnell MV,  Solomon SD, Rayan ME, Come PC, Goldhaber SZ, Lee RT.  Am J Cardiol.  1996; 78 (4): 469-73
• Pathogenic mechanisms of atherosclerosis: effect of lipid lowering on the biology of atherosclerosis. Ganz P,  Creager MA, Fang JC, McConnell MV, Lee RT, Libby P, Selwyn AP.  Am J Med.  1996; 101 (4A): 4A10S-16S
• Identification of anomalous coronary arteries and their anatomic course by magnetic resonance coronary angiography. McConnell MV,  Ganz P, Selwyn AP, Li W, Edelman RR, Manning WJ.  Circulation.  1995; 92 (11): 3158-62
• Comparison of CD4 and CD8 T cell reactivity in high-responder and low-responder strain combinations in the rat. McConnell MV,  Hall BM.  Transplant Proc.  1989; 21 (2): 3294-5
• Cellular basis of allograft rejection in vivo. V. Examination of the mechanisms responsible for the differing efficacy of monoclonal antibody to CD4+ T cell subsets in low- and high-responder rat strains. Ilano AL,  McConnell MV, Gurley KE, Spinelli A, Pearce NW, Hall BM.  J Immunol.  1989; 143 (9): 2828-36
• Pacemaker diagnostic diagrams. Olson WH,  McConnell MV, Sah RL, Beck RC, Sutton R.  Pacing Clin Electrophysiol.  1985; 8 (5): 691-700