John Hotson

Administrative Appointments

• Chief of Neurology, Santa Clara Valley Medical Center , (1985– 2009 )

Honors and Awards

• Neurology Clerkship Teaching Award, Department of Neurology, Stanford University School of Medicine (2004-2007, 2009)
• Lysia Fornia Award for Teaching Excellence, Department of Neurology, Stanford University School of Medicine (1991)

Professional Education

• BA, Stanford University Psychology (1968)
• MD (honors), University of Washington Medicine (1972)

Research Interests

The response and recovery of human visual, eye movement and related cognitive systems after acquired neurological disorders is a main area of interest. Experimental designs combine human brain neurophysiology techniques with psychophysics methods. We currently use transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) as probes to test the postulate that visual perceptual learning alters early visual cortex.

Publications

• Visual perceptual learning is similar across the extrafoveal central visual fields K. Neary,  S. Anand, J.R. Hotson.  Restorative Neurology & Neuroscience.  2009; 27 (3): 181-188
• Perceptual learning of line orientation modifies the effects of transcranial magnetic stimulation of visual cortex. Neary K,  Anand S, Hotson J.  Experimental Brain Research.  2005; 162 23-34
• Tracing the timing of human analysis of motion and chromatic signals from occipital to temporo-parieto-occipital cortex: a transcranial magnetic stimulation study. Anand S,  Olson JD, Hotson JR.  Vision Res.  1998; 38 (17): 2619-27
• Acute vestibular syndrome. Hotson JR,  Baloh RW.  N Engl J Med.  1998; 339 (10): 680-5
• Transcranial magnetic stimulation of extrastriate cortex degrades human motion direction discrimination. Hotson J,  Braun D, Herzberg W, Boman D.  Vision Res.  1994; 34 (16): 2115-23
• Correlation of median forearm conduction velocity with carpal tunnel syndrome severity. Havton LA,  Hotson JR, Kellerth JO.  Clinical Neurophysiology.  2007; 118 (4): 781
• Transcranial magnetic stimulation: neurophysiological applications and safety. Anand S,  Hotson J.  Brain Cogn.  2002; 50 (3): 366-86
• Partial peripheral motor nerve lesions induce changes in the conduction properties of remaining intact motoneurons. Havton LA,  Hotson JR, Kellerth JO.  Muscle Nerve.  2001; 24 (5): 662-6
• The selectivity and timing of motion processing in human temporo-parieto-occipital and occipital cortex: a transcranial magnetic stimulation study. Hotson JR,  Anand S.  Neuropsychologia.  1999; 37 (2): 169-79
• Rapid-rate transcranial magnetic stimulation of human frontal cortex can evoke saccades under facilitating conditions. Li J,  Olson J, Anand S, Hotson J.  Electroencephalogr Clin Neurophysiol.  1997; 105 (3): 246-54
• Anticipatory smooth eye movements and predictive pursuit after unilateral lesions in human brain. Braun DI,  Boman DK, Hotson JR.  Exp Brain Res.  1996; 110 (1): 111-6
• Stationary and pursuit visual fixation share similar behavior. Boman D,  Braun D, Hotson J.  Vision Res.  1996; 36 (5): 751-63
• Prolonged confusion with nocturnal wandering arising from NREM and REM sleep: a case report. Kushida CA,  Clerk AA, Kirsch CM, Hotson JR, Guilleminault C.  Sleep.  1995; 18 (9): 757-64
• Transesophageal echocardiographic findings in stroke subtypes. Albers GW,  Comess KA, DeRook FA, Bracci P, Atwood JE, Bolger A, Hotson J.  Stroke.  1994; 25 (1): 23-8
• Predictive smooth pursuit eye movements near abrupt changes in motion direction. Boman DK,  Hotson JR.  Vision Res.  1992; 32 (4): 675-89
• Memory-contingent saccades and the substantia nigra postulate for essential blepharospasm. Hotson JR,  Boman DR.  Brain.  1991; 114 ( Pt 1A) 295-307
• Differential diagnosis of choreiform tardive dyskinesia. Hyde TM,  Hotson JR, Kleinman JE.  J Neuropsychiatry Clin Neurosci.  1991; 3 (3): 255-68
• Motion perception prominence alters anticipatory slow eye movements. Boman DK,  Hotson JR.  Exp Brain Res.  1989; 74 (3): 555-62
• Stimulus conditions that enhance anticipatory slow eye movements. Boman DK,  Hotson JR.  Vision Res.  1988; 28 (10): 1157-65
• Neurologic complications of cardiac transplantation. Hotson JR,  Enzmann DR.  Neurol Clin.  1988; 6 (2): 349-65
• Vertical and horizontal saccades in aging and dementia - failure to inhibit anticipatory saccades. . Hotson JR,  Steinke GW.  Neuro-Ophthalmology.  1988; 8 267-273
• Smooth pursuit training and disruption: directional differences and nystagmus Boman DK,  Hotson JR.  Neuro-Ophthalmology.  1987; 7 185-194
• The search for a physiologic marker of Machado-Joseph disease. Hotson JR,  Langston EB, Louis AA, Rosenberg RN.  Neurology.  1987; 37 (1): 112-6
• Saccade responses to dopamine in human MPTP-induced parkinsonism. Hotson JR,  Langston EB, Langston JW.  Ann Neurol.  1986; 20 (4): 456-63
• Regional cooling of human nerve and slowed Na+ inactivation. Louis AA,  Hotson JR.  Electroencephalogr Clin Neurophysiol.  1986; 63 (4): 371-5
• Clinical detection of acute vestibulocerebellar disorders. Hotson JR,  West J Med.  1984; 140 (6): 910-3
• Convergence-initiated voluntary flutter: a normal intrinsic capability in man. Hotson JR,  Brain Res.  1984; 294 (2): 299-304
• Vertical saccades in Huntington's disease and non-degenerative choreoathetoid disorders Hotson JR,  Louis AA, Langston EB, Moreno JA.  Neuro-Ophthalmology.  1984; 4 207-217
• Hyperviscosity-induced dementia. Mueller J,  Hotson JR, Langston JW.  Neurology.  1983; 33 (1): 101-3
• Amitriptyline: another cause of internuclear ophthalmoplegia with coma. Hotson JR,  Sachdev HS.  Ann Neurol.  1982; 12 (1): 62
• Cerebellar control of fixation eye movements. Hotson JR,  Neurology.  1982; 32 (1): 31-6
• Penicillin- and barium-induced epileptiform bursting in hippocampal neurons: actions on Ca++ and K+ potentials. Hotson JR,  Prince DA.  Ann Neurol.  1981; 10 (1): 11-7
• Modern neurosyphilis: a partially treated chronic meningitis. Hotson JR,  West J Med.  1981; 135 (3): 191-200
• A calcium-activated hyperpolarization follows repetitive firing in hippocampal neurons. Hotson JR,  Prince DA.  J Neurophysiol.  1980; 43 (2): 409-19
• Anomalous inward rectification in hippocampal neurons. Hotson JR,  Prince DA, Schwartzkroin PA.  J Neurophysiol.  1979; 42 (3): 889-95
• Penicillin- and barium-induced epileptiform bursting in hippocampal neurons: actions on calcium- and potassium-dependent potentials. Hotson JR,  Prince DA.  Trans Am Neurol Assoc.  1978; 103 56-8
• The neurological complications of cardiac transplantation. Hotson JR,  Pedley TA.  Brain.  1976; 99 (4): 673-94
• Disulfiram-induced encephalopathy. Hotson JR,  Langston JW.  Arch Neurol.  1976; 33 (2): 141-2
• Extracellular potassium concentration changes during propagated seizures in neocortex. Hotson JR,  Sypert GW, Ward AA.  Exp Neurol.  1973; 38 (1): 20-6