Stanley Falkow

Industry Relationships

Stanford is committed to ethical and transparent interactions with our industry partners. It is our policy to disclose payments of $5,000 or more, equity valued at $5,000 or more in a publicly traded company, or any equity in a privately held company, to physicians and scientists employed by Stanford University from companies or other commercial entities with which they interact as part of their professional activities. 

• Consulting: Protein Design Lab Inc

Research Interests

Dr. Falkow is no longer taking students or postdoctoral fellows in his laboratory.

Please contact either Denise Monack (dmonack@stanford.edu) or Manuel Amieva (amieva@stanford.edu).

Publications

• The fortunate professor. Falkow S,  Annu Rev Microbiol.  2008; 62 1-18
• I never met a microbe I didn't like. Falkow S,  Nat Med.  2008; 14 (10): 1053-7
• Is persistent bacterial infection good for your health? Falkow S,  Cell.  2006; 124 (4): 699-702
• The uses of green fluorescent protein in prokaryotes. Valdivia RH,  Cormack BP, Falkow S.  Methods Biochem Anal.  2006; 47 163-78
• Microarray-based detection of Salmonella enterica serovar Typhimurium transposon mutants that cannot survive in macrophages and mice. Chan K,  Kim CC, Falkow S.  Infect Immun.  2005; 73 (9): 5438-49
• Helicobacter pylori and gastric cancer: what can be learned by studying the response of gastric epithelial cells to the infection? Mueller A,  Falkow S, Amieva MR.  Cancer Epidemiol Biomarkers Prev.  2005; 14 (8): 1859-64
• Mig-14 is an inner membrane-associated protein that promotes Salmonella typhimurium resistance to CRAMP, survival within activated macrophages and persistent infection. Brodsky IE,  Ghori N, Falkow S, Monack D.  Mol Microbiol.  2005; 55 (3): 954-72
• The adaptor molecules LAT and SLP-76 are specifically targeted by Yersinia to inhibit T cell activation. Gerke C,  Falkow S, Chien YH.  J Exp Med.  2005; 201 (3): 361-71
• The Campylobacter jejuni stringent response controls specific stress survival and virulence-associated phenotypes. Gaynor EC,  Wells DH, MacKichan JK, Falkow S.  Mol Microbiol.  2005; 56 (1): 8-27
• The role of antigenic drive and tumor-infiltrating accessory cells in the pathogenesis of helicobacter-induced mucosa-associated lymphoid tissue lymphoma. Mueller A,  O'rourke J, Chu P, Chu A, Dixon MF, Bouley DM, Lee A, Falkow S.  Am J Pathol.  2005; 167 (3): 797-812
• The genome-sequenced variant of Campylobacter jejuni NCTC 11168 and the original clonal clinical isolate differ markedly in colonization, gene expression, and virulence-associated phenotypes. Gaynor EC,  Cawthraw S, Manning G, MacKichan JK, Falkow S, Newell DG.  J Bacteriol.  2004; 186 (2): 503-17
• Salmonella typhimurium persists within macrophages in the mesenteric lymph nodes of chronically infected Nramp1+/+ mice and can be reactivated by IFNgamma neutralization. Monack DM,  Bouley DM, Falkow S.  J Exp Med.  2004; 199 (2): 231-41
• Comparison of Campylobacter jejuni isolates implicated in Guillain-Barré syndrome and strains that cause enteritis by a DNA microarray. Leonard EE,  Tompkins LS, Falkow S, Nachamkin I.  Infect Immun.  2004; 72 (2): 1199-203
• Evolutionary genetics: CCR5 mutation and plague protection. Mecsas J,  Franklin G, Kuziel WA, Brubaker RR, Falkow S, Mosier DE.  Nature.  2004; 427 (6975): 606
• Molecular Koch's postulates applied to bacterial pathogenicity--a personal recollection 15 years later. Falkow S,  Nat Rev Microbiol.  2004; 2 (1): 67-72
• Breaking into the epithelial apical-junctional complex--news from pathogen hackers. Vogelmann R,  Amieva MR, Falkow S, Nelson WJ.  Curr Opin Cell Biol.  2004; 16 (1): 86-93
• LuxS is required for persistent pneumococcal carriage and expression of virulence and biosynthesis genes. Joyce EA,  Kawale A, Censini S, Kim CC, Covacci A, Falkow S.  Infect Immun.  2004; 72 (5): 2964-75
• Delineation of upstream signaling events in the salmonella pathogenicity island 2 transcriptional activation pathway. Kim CC,  Falkow S.  J Bacteriol.  2004; 186 (14): 4694-704
• Chronic Helicobacter pylori infection with Sydney strain 1 and a newly identified mouse-adapted strain (Sydney strain 2000) in C57BL/6 and BALB/c mice. Thompson LJ,  Danon SJ, Wilson JE, O'Rourke JL, Salama NR, Falkow S, Mitchell H, Lee A.  Infect Immun.  2004; 72 (8): 4668-79
• Phosphorylation-independent effects of CagA during interaction between Helicobacter pylori and T84 polarized monolayers. El-Etr SH,  Mueller A, Tompkins LS, Falkow S, Merrell DS.  J Infect Dis.  2004; 190 (8): 1516-23
• Persistent bacterial infections: the interface of the pathogen and the host immune system. Monack DM,  Mueller A, Falkow S.  Nat Rev Microbiol.  2004; 2 (9): 747-65
• Profiling of microdissected gastric epithelial cells reveals a cell type-specific response to Helicobacter pylori infection. Mueller A,  Merrell DS, Grimm J, Falkow S.  Gastroenterology.  2004; 127 (5): 1446-62
• The Campylobacter jejuni dccRS two-component system is required for optimal in vivo colonization but is dispensable for in vitro growth. MacKichan JK,  Gaynor EC, Chang C, Cawthraw S, Newell DG, Miller JF, Falkow S.  Mol Microbiol.  2004; 54 (5): 1269-86
• virK, somA and rcsC are important for systemic Salmonella enterica serovar Typhimurium infection and cationic peptide resistance. Detweiler CS,  Monack DM, Brodsky IE, Mathew H, Falkow S.  Mol Microbiol.  2003; 48 (2): 385-400
• Genomic comparison of Salmonella enterica serovars and Salmonella bongori by use of an S. enterica serovar typhimurium DNA microarray. Chan K,  Baker S, Kim CC, Detweiler CS, Dougan G, Falkow S.  J Bacteriol.  2003; 185 (2): 553-63
• Disruption of the epithelial apical-junctional complex by Helicobacter pylori CagA. Amieva MR,  Vogelmann R, Covacci A, Tompkins LS, Nelson WJ, Falkow S.  Science.  2003; 300 (5624): 1430-4
• pH-regulated gene expression of the gastric pathogen Helicobacter pylori. Merrell DS,  Goodrich ML, Otto G, Tompkins LS, Falkow S.  Infect Immun.  2003; 71 (6): 3529-39
• Modulation of virulence by two acidified nitrite-responsive loci of Salmonella enterica serovar Typhimurium. Kim CC,  Monack D, Falkow S.  Infect Immun.  2003; 71 (6): 3196-205
• Gene expression profiling of Helicobacter pylori reveals a growth-phase-dependent switch in virulence gene expression. Thompson LJ,  Merrell DS, Neilan BA, Mitchell H, Lee A, Falkow S.  Infect Immun.  2003; 71 (5): 2643-55
• Growth phase-dependent response of Helicobacter pylori to iron starvation. Merrell DS,  Thompson LJ, Kim CC, Mitchell H, Tompkins LS, Lee A, Falkow S.  Infect Immun.  2003; 71 (11): 6510-25
• Protective immunity against Helicobacter is characterized by a unique transcriptional signature. Mueller A,  O'Rourke J, Chu P, Kim CC, Sutton P, Lee A, Falkow S.  Proc Natl Acad Sci U S A.  2003; 100 (21): 12289-94
• Significance analysis of lexical bias in microarray data. Kim CC,  Falkow S.  BMC Bioinformatics.  2003; 4 12
• Distinct gene expression profiles characterize the histopathological stages of disease in Helicobacter-induced mucosa-associated lymphoid tissue lymphoma. Mueller A,  O'Rourke J, Grimm J, Guillemin K, Dixon MF, Lee A, Falkow S.  Proc Natl Acad Sci U S A.  2003; 100 (3): 1292-7
• Use of an open-reading frame-specific Campylobacter jejuni DNA microarray as a new genotyping tool for studying epidemiologically related isolates. Leonard EE,  Takata T, Blaser MJ, Falkow S, Tompkins LS, Gaynor EC.  J Infect Dis.  2003; 187 (4): 691-4
• Improved analytical methods for microarray-based genome-composition analysis. Kim CC,  Joyce EA, Chan K, Falkow S.  Genome Biol.  2002; 3 (11): RESEARCH0065
• Dissecting Host-Pathogen Molecular Interactions with Microarrays S. Falkow.,  Detweiler, C.S..  In: Methods in Microbiology, Vol. 31, Academic Press, Ltd..  2002;
• Caenorhabditis elegans: plague bacteria biofilm blocks food intake. Darby C,  Hsu JW, Ghori N, Falkow S.  Nature.  2002; 417 (6886): 243-4
• Complex pattern of Mycobacterium marinum gene expression during long-term granulomatous infection. Chan K,  Knaak T, Satkamp L, Humbert O, Falkow S, Ramakrishnan L.  Proc Natl Acad Sci U S A.  2002; 99 (6): 3920-5
• Cag pathogenicity island-specific responses of gastric epithelial cells to Helicobacter pylori infection. Guillemin K,  Salama NR, Tompkins LS, Falkow S.  Proc Natl Acad Sci U S A.  2002; 99 (23): 15136-41
• mig-14 is a Salmonella gene that plays a role in bacterial resistance to antimicrobial peptides. Brodsky IE,  Ernst RK, Miller SI, Falkow S.  J Bacteriol.  2002; 184 (12): 3203-13
• Redefining bacterial populations: a post-genomic reformation. Joyce EA,  Chan K, Salama NR, Falkow S.  Nat Rev Genet.  2002; 3 (6): 462-73
• Identification of Streptococcus bovis biotype I strains among S. bovis clinical isolates by PCR. Songy WB,  Ruoff KL, Facklam RR, Ferraro MJ, Falkow S.  J Clin Microbiol.  2002; 40 (8): 2913-8
• Helicobacter pylori enter and survive within multivesicular vacuoles of epithelial cells. Amieva MR,  Salama NR, Tompkins LS, Falkow S.  Cell Microbiol.  2002; 4 (10): 677-90
• Salmonella-induced macrophage death: the role of caspase-1 in death and inflammation. Monack DM,  Navarre WW, Falkow S.  Microbes Infect.  2001 Nov-Dec; 3 (14-15): 1201-12
• Salmonella pathogenicity island 2-dependent macrophage death is mediated in part by the host cysteine protease caspase-1. Monack DM,  Detweiler CS, Falkow S.  Cell Microbiol.  2001; 3 (12): 825-37
• Dynamic nature of host-pathogen interactions in Mycobacterium marinum granulomas. Bouley DM,  Ghori N, Mercer KL, Falkow S, Ramakrishnan L.  Infect Immun.  2001; 69 (12): 7820-31
• Mimicry of a G protein mutation by pertussis toxin expression in transgenic Caenorhabditis elegans. Darby C,  Falkow S.  Infect Immun.  2001; 69 (10): 6271-5
• The meaning and impact of the human genome sequence for microbiology. Relman DA,  Falkow S.  Trends Microbiol.  2001; 9 (5): 206-8
• New approaches for validation of lethal phenotypes and genetic reversion in Helicobacter pylori. McDaniel TK,  Dewalt KC, Salama NR, Falkow S.  Helicobacter.  2001; 6 (1): 15-23
• Host microarray analysis reveals a role for the Salmonella response regulator phoP in human macrophage cell death. Detweiler CS,  Cunanan DB, Falkow S.  Proc Natl Acad Sci U S A.  2001; 98 (10): 5850-5
• Identification of attenuated Yersinia pseudotuberculosis strains and characterization of an orogastric infection in BALB/c mice on day 5 postinfection by signature-tagged mutagenesis. Mecsas J,  Bilis I, Falkow S.  Infect Immun.  2001; 69 (5): 2779-87
• Bile-induced 'pili' in Campylobacter jejuni are bacteria-independent artifacts of the culture medium. Gaynor EC,  Ghori N, Falkow S.  Mol Microbiol.  2001; 39 (6): 1546-9
• Identification of Legionella pneumophila genes important for infection of amoebas by signature-tagged mutagenesis. Polesky AH,  Ross JT, Falkow S, Tompkins LS.  Infect Immun.  2001; 69 (2): 977-87
• Vacuolating cytotoxin of Helicobacter pylori plays a role during colonization in a mouse model of infection. Salama NR,  Otto G, Tompkins L, Falkow S.  Infect Immun.  2001; 69 (2): 730-6
• A whole-genome microarray reveals genetic diversity among Helicobacter pylori strains. Salama N,  Guillemin K, McDaniel TK, Sherlock G, Tompkins L, Falkow S.  Proc Natl Acad Sci U S A.  2000; 97 (26): 14668-73
• mig-14 is a horizontally acquired, host-induced gene required for salmonella enterica lethal infection in the murine model of typhoid fever. Valdivia RH,  Cirillo DM, Lee AK, Bouley DM, Falkow S.  Infect Immun.  2000; 68 (12): 7126-31
• Apoptosis as a common bacterial virulence strategy. Monack D,  Falkow S.  Int J Med Microbiol.  2000; 290 (1): 7-13
• OmpR regulates the two-component system SsrA-ssrB in Salmonella pathogenicity island 2. Lee AK,  Detweiler CS, Falkow S.  J Bacteriol.  2000; 182 (3): 771-81
• Living in stools is not as dumb as you think. Falkow S,  J Bacteriol.  2000; 182 (12): 3319-22
• Granuloma-specific expression of Mycobacterium virulence proteins from the glycine-rich PE-PGRS family. Ramakrishnan L,  Federspiel NA, Falkow S.  Science.  2000; 288 (5470): 1436-9
• The good old days are now. Falkow S,  Trends Microbiol.  2000; 8 (5): 198-9
• Salmonella exploits caspase-1 to colonize Peyer's patches in a murine typhoid model. Monack DM,  Hersh D, Ghori N, Bouley D, Zychlinsky A, Falkow S.  J Exp Med.  2000; 192 (2): 249-58
• Suppression of T and B lymphocyte activation by a Yersinia pseudotuberculosis virulence factor, yopH. Yao T,  Mecsas J, Healy JI, Falkow S, Chien Y.  J Exp Med.  1999; 190 (9): 1343-50
• Altered states: involvement of phosphorylated CagA in the induction of host cellular growth changes by Helicobacter pylori. Segal ED,  Cha J, Lo J, Falkow S, Tompkins LS.  Proc Natl Acad Sci U S A.  1999; 96 (25): 14559-64
• Genomic clues for defining bacterial pathogenicity. Salama NR,  Falkow S.  Microbes Infect.  1999; 1 (8): 615-9
• Bacterial epithelial cell cross talk. Raupach B,  Mecsas J, Heczko U, Falkow S, Finlay BB.  Curr Top Microbiol Immunol.  1999; 236 137-61
• Cellular Microbiology is launched. Falkow S,  Cell Microbiol.  1999; 1 (1): 3-6
• An adhesin of the yeast pathogen Candida glabrata mediating adherence to human epithelial cells. Cormack BP,  Ghori N, Falkow S.  Science.  1999; 285 (5427): 578-82
• Sequence anomalies in the Cag7 gene of the Helicobacter pylori pathogenicity island. Liu G,  McDaniel TK, Falkow S, Karlin S.  Proc Natl Acad Sci U S A.  1999; 96 (12): 7011-6
• Efficient homologous and illegitimate recombination in the opportunistic yeast pathogen Candida glabrata. Cormack BP,  Falkow S.  Genetics.  1999; 151 (3): 979-87
• Who speaks for the microbes? Falkow S,  Emerg Infect Dis.  1998 Jul-Sep; 4 (3): 495-7
• Flow cytometry and bacterial pathogenesis. Valdivia RH,  Falkow S.  Curr Opin Microbiol.  1998; 1 (3): 359-63
• Macrophage-dependent induction of the Salmonella pathogenicity island 2 type III secretion system and its role in intracellular survival. Cirillo DM,  Valdivia RH, Monack DM, Falkow S.  Mol Microbiol.  1998; 30 (1): 175-88
• Yersinia-induced apoptosis in vivo aids in the establishment of a systemic infection of mice. Monack DM,  Mecsas J, Bouley D, Falkow S.  J Exp Med.  1998; 188 (11): 2127-37
• Constitutive and inducible green fluorescent protein expression in Bartonella henselae. Lee AK,  Falkow S.  Infect Immun.  1998; 66 (8): 3964-7
• The Yersinia Yops inhibit invasion of Listeria, Shigella and Edwardsiella but not Salmonella into epithelial cells. Mecsas J,  Raupach B, Falkow S.  Mol Microbiol.  1998; 28 (6): 1269-81
• Probing the intracellular life of bacteria. Falkow S,  Harvey Lect.  1997-1998; 93 65-74
• Induction of host signal transduction pathways by Helicobacter pylori. Segal ED,  Lange C, Covacci A, Tompkins LS, Falkow S.  Proc Natl Acad Sci U S A.  1997; 94 (14): 7595-9
• Microbial pathogenesis: genomics and beyond. Strauss EJ,  Falkow S.  Science.  1997; 276 (5313): 707-12
• The unique trafficking pattern of Salmonella typhimurium-containing phagosomes in murine macrophages is independent of the mechanism of bacterial entry. Rathman M,  Barker LP, Falkow S.  Infect Immun.  1997; 65 (4): 1475-85
• Yeast-enhanced green fluorescent protein (yEGFP)a reporter of gene expression in Candida albicans. Cormack BP,  Bertram G, Egerton M, Gow NA, Falkow S, Brown AJ.  Microbiology.  1997; 143 ( Pt 2) 303-11
• Perspectives series: host/pathogen interactions. Invasion and intracellular sorting of bacteria: searching for bacterial genes expressed during host/pathogen interactions. Falkow S,  J Clin Invest.  1997; 100 (2): 239-43
• An Edwardsiella tarda strain containing a mutation in a gene with homology to shlB and hpmB is defective for entry into epithelial cells in culture. Strauss EJ,  Ghori N, Falkow S.  Infect Immun.  1997; 65 (9): 3924-32
• Yersinia signals macrophages to undergo apoptosis and YopJ is necessary for this cell death. Monack DM,  Mecsas J, Ghori N, Falkow S.  Proc Natl Acad Sci U S A.  1997; 94 (19): 10385-90
• Probing bacterial gene expression within host cells. Valdivia RH,  Falkow S.  Trends Microbiol.  1997; 5 (9): 360-3
• Fluorescence-based isolation of bacterial genes expressed within host cells. Valdivia RH,  Falkow S.  Science.  1997; 277 (5334): 2007-11
• Mycobacterium marinum causes both long-term subclinical infection and acute disease in the leopard frog (Rana pipiens). Ramakrishnan L,  Valdivia RH, McKerrow JH, Falkow S.  Infect Immun.  1997; 65 (2): 767-73
• A crtB homolog essential for photochromogenicity in Mycobacterium marinum: isolation, characterization, and gene disruption via homologous recombination. Ramakrishnan L,  Tran HT, Federspiel NA, Falkow S.  J Bacteriol.  1997; 179 (18): 5862-8
• Applications for green fluorescent protein (GFP) in the study of host-pathogen interactions. Valdivia RH,  Hromockyj AE, Monack D, Ramakrishnan L, Falkow S.  Gene.  1996; 173 (1 Spec No): 47-52
• Helicobacter pylori attachment to gastric cells induces cytoskeletal rearrangements and tyrosine phosphorylation of host cell proteins. Segal ED,  Falkow S, Tompkins LS.  Proc Natl Acad Sci U S A.  1996; 93 (3): 1259-64
• Acidification of phagosomes containing Salmonella typhimurium in murine macrophages. Rathman M,  Sjaastad MD, Falkow S.  Infect Immun.  1996; 64 (7): 2765-73
• Salmonella typhimurium invasion induces apoptosis in infected macrophages. Monack DM,  Raupach B, Hromockyj AE, Falkow S.  Proc Natl Acad Sci U S A.  1996; 93 (18): 9833-8
• Bacterial genetics by flow cytometry: rapid isolation of Salmonella typhimurium acid-inducible promoters by differential fluorescence induction. Valdivia RH,  Falkow S.  Mol Microbiol.  1996; 22 (2): 367-78
• FACS-optimized mutants of the green fluorescent protein (GFP). Cormack BP,  Valdivia RH, Falkow S.  Gene.  1996; 173 (1 Spec No): 33-8
• The new path to preventing ulcers. Tompkins LS,  Falkow S.  Science.  1995; 267 (5204): 1621-2
• Bartonella henselae and Bartonella quintana adherence to and entry into cultured human epithelial cells. Batterman HJ,  Peek JA, Loutit JS, Falkow S, Tompkins LS.  Infect Immun.  1995; 63 (11): 4553-6
• Microbes as tools for cell biology. Introduction. Falkow S,  Methods Cell Biol.  1994; 45 xv-xvi
• Salmonella typhimurium initiates murine infection by penetrating and destroying the specialized epithelial M cells of the Peyer's patches. Jones BD,  Ghori N, Falkow S.  J Exp Med.  1994; 180 (1): 15-23
• Mycobacterium marinum persists in cultured mammalian cells in a temperature-restricted fashion. Ramakrishnan L,  Falkow S.  Infect Immun.  1994; 62 (8): 3222-9
• Growth of Legionella pneumophila in Acanthamoeba castellanii enhances invasion. Cirillo JD,  Falkow S, Tompkins LS.  Infect Immun.  1994; 62 (8): 3254-61
• Identification and characterization of a Salmonella typhimurium oxygen-regulated gene required for bacterial internalization. Jones BD,  Falkow S.  Infect Immun.  1994; 62 (9): 3745-52
• Attaching and effacing locus of a Citrobacter freundii biotype that causes transmissible murine colonic hyperplasia. Schauer DB,  Falkow S.  Infect Immun.  1993; 61 (6): 2486-92
• Mutation in the pla gene of Yersinia pestis alters the course of the plague bacillus-flea (Siphonaptera: Ceratophyllidae) interaction. McDonough KA,  Barnes AM, Quan TJ, Montenieri J, Falkow S.  J Med Entomol.  1993; 30 (4): 772-80
• Ruffles induced by Salmonella and other stimuli direct macropinocytosis of bacteria. Francis CL,  Ryan TA, Jones BD, Smith SJ, Falkow S.  Nature.  1993; 364 (6438): 639-42
• Isolation and characterization of "Flexispira rappini" from laboratory mice. Schauer DB,  Ghori N, Falkow S.  J Clin Microbiol.  1993; 31 (10): 2709-14
• Cloning of Bordetella bronchiseptica urease genes and analysis of colonization by a urease-negative mutant strain in a guinea-pig model. Monack DM,  Falkow S.  Mol Microbiol.  1993; 10 (3): 545-53
• Salmonella typhimurium induces membrane ruffling by a growth factor-receptor-independent mechanism. Jones BD,  Paterson HF, Hall A, Falkow S.  Proc Natl Acad Sci U S A.  1993; 90 (21): 10390-4
• High-molecular-weight proteins of nontypable Haemophilus influenzae mediate attachment to human epithelial cells. St Geme JW,  Falkow S, Barenkamp SJ.  Proc Natl Acad Sci U S A.  1993; 90 (7): 2875-9
• The eae gene of Citrobacter freundii biotype 4280 is necessary for colonization in transmissible murine colonic hyperplasia. Schauer DB,  Falkow S.  Infect Immun.  1993; 61 (11): 4654-61
• The Yersinia tyrosine phosphatase: specificity of a bacterial virulence determinant for phosphoproteins in the J774A.1 macrophage. Bliska JB,  Clemens JC, Dixon JE, Falkow S.  J Exp Med.  1992; 176 (6): 1625-30
• The interaction of bacteria with mammalian cells. Falkow S,  Isberg RR, Portnoy DA.  Annu Rev Cell Biol.  1992; 8 333-63
• The invasin protein of Yersinia enterocolitica: internalization of invasin-bearing bacteria by eukaryotic cells is associated with reorganization of the cytoskeleton. Young VB,  Falkow S, Schoolnik GK.  J Cell Biol.  1992; 116 (1): 197-207
• Identification of a Salmonella typhimurium invasion locus by selection for hyperinvasive mutants. Lee CA,  Jones BD, Falkow S.  Proc Natl Acad Sci U S A.  1992; 89 (5): 1847-51
• Bacterial resistance to complement killing mediated by the Ail protein of Yersinia enterocolitica. Bliska JB,  Falkow S.  Proc Natl Acad Sci U S A.  1992; 89 (8): 3561-5
• Capsule loss by Haemophilus influenzae type b results in enhanced adherence to and entry into human cells. St Geme JW,  Falkow S.  J Infect Dis.  1992; 165 Suppl 1 S117-8
• Morphological and cytoskeletal changes in epithelial cells occur immediately upon interaction with Salmonella typhimurium grown under low-oxygen conditions. Francis CL,  Starnbach MN, Falkow S.  Mol Microbiol.  1992; 6 (21): 3077-87
• Identification of uncultured microorganisms: expanding the spectrum of characterized microbial pathogens. Relman DA,  Falkow S.  Infect Agents Dis.  1992; 1 (5): 245-53
• Identification of the uncultured bacillus of Whipple's disease. Relman DA,  Schmidt TM, MacDermott RP, Falkow S.  N Engl J Med.  1992; 327 (5): 293-301
• Invasion by Salmonella typhimurium is affected by the direction of flagellar rotation. Jones BD,  Lee CA, Falkow S.  Infect Immun.  1992; 60 (6): 2475-80
• Characterization of interactions of enteropathogenic Escherichia coli O127:H6 with mammalian cells in vitro. Francis CL,  Jerse AE, Kaper JB, Falkow S.  J Infect Dis.  1991; 164 (4): 693-703
• Loss of capsule expression by Haemophilus influenzae type b results in enhanced adherence to and invasion of human cells. St Geme JW,  Falkow S.  Infect Immun.  1991; 59 (4): 1325-33
• Identification of Bordetella pertussis regulatory sequences required for transcriptional activation of the fhaB gene and autoregulation of the bvgAS operon. Roy CR,  Falkow S.  J Bacteriol.  1991; 173 (7): 2385-92
• Bacterial entry into eukaryotic cells. Falkow S,  Cell.  1991; 65 (7): 1099-102
• Surface structures and adherence properties of diverse strains of Haemophilus influenzae biogroup aegyptius. St Geme JW,  Gilsdorf JR, Falkow S.  Infect Immun.  1991; 59 (10): 3366-71
• Tyrosine phosphate hydrolysis of host proteins by an essential Yersinia virulence determinant. Bliska JB,  Guan KL, Dixon JE, Falkow S.  Proc Natl Acad Sci U S A.  1991; 88 (4): 1187-91
• Haemophilus influenzae adheres to and enters cultured human epithelial cells. St Geme JW,  Falkow S.  Infect Immun.  1990; 58 (12): 4036-44
• Sequence, localization and function of the invasin protein of Yersinia enterocolitica. Young VB,  Miller VL, Falkow S, Schoolnik GK.  Mol Microbiol.  1990; 4 (7): 1119-28
• Recognition of a bacterial adhesion by an integrin: macrophage CR3 (alpha M beta 2, CD11b/CD18) binds filamentous hemagglutinin of Bordetella pertussis. Relman D,  Tuomanen E, Falkow S, Golenbock DT, Saukkonen K, Wright SD.  Cell.  1990; 61 (7): 1375-82
• The ability of Salmonella to enter mammalian cells is affected by bacterial growth state. Lee CA,  Falkow S.  Proc Natl Acad Sci U S A.  1990; 87 (11): 4304-8
• Detection of Shigella in feces using DNA amplification. Frankel G,  Riley L, Giron JA, Valmassoi J, Friedmann A, Strockbine N, Falkow S, Schoolnik GK.  J Infect Dis.  1990; 161 (6): 1252-6
• Autogenous regulation of the Bordetella pertussis bvgABC operon. Roy CR,  Miller JF, Falkow S.  Proc Natl Acad Sci U S A.  1990; 87 (10): 3763-7
• Nonpathogenic isolates of Yersinia enterocolitica do not contain functional inv-homologous sequences. Pierson DE,  Falkow S.  Infect Immun.  1990; 58 (4): 1059-64
• Nucleotide sequence of the Yersinia enterocolitica ail gene and characterization of the Ail protein product. Miller VL,  Bliska JB, Falkow S.  J Bacteriol.  1990; 172 (2): 1062-9
• The agent of bacillary angiomatosis. An approach to the identification of uncultured pathogens. Relman DA,  Loutit JS, Schmidt TM, Falkow S, Tompkins LS.  N Engl J Med.  1990; 323 (23): 1573-80
• A Yersinia pestis-specific DNA fragment encodes temperature-dependent coagulase and fibrinolysin-associated phenotypes. McDonough KA,  Falkow S.  Mol Microbiol.  1989; 3 (6): 767-75
• Species-specific detection of Legionella pneumophila in water by DNA amplification and hybridization. Starnbach MN,  Falkow S, Tompkins LS.  J Clin Microbiol.  1989; 27 (6): 1257-61
• The bvgA gene of Bordetella pertussis encodes a transcriptional activator required for coordinate regulation of several virulence genes. Roy CR,  Miller JF, Falkow S.  J Bacteriol.  1989; 171 (11): 6338-44
• Expression of gonococcal protein II in Escherichia coli by translational fusion. Palmer L,  Brooks GF, Falkow S.  Mol Microbiol.  1989; 3 (5): 663-71
• Analysis of Bordetella pertussis virulence gene regulation by use of transcriptional fusions in Escherichia coli. Miller JF,  Roy CR, Falkow S.  J Bacteriol.  1989; 171 (11): 6345-8
• Use of a Chlamydia trachomatis DNA probe for detection of ocular chlamydiae. Dean D,  Palmer L, Pant CR, Courtright P, Falkow S, O'Hanley P.  J Clin Microbiol.  1989; 27 (5): 1062-7
• Phase variants of Bordetella bronchiseptica arise by spontaneous deletions in the vir locus. Monack DM,  Arico B, Rappuoli R, Falkow S.  Mol Microbiol.  1989; 3 (12): 1719-28
• Filamentous hemagglutinin of Bordetella pertussis: nucleotide sequence and crucial role in adherence. Relman DA,  Domenighini M, Tuomanen E, Rappuoli R, Falkow S.  Proc Natl Acad Sci U S A.  1989; 86 (8): 2637-41
• Epithelial cell surfaces induce Salmonella proteins required for bacterial adherence and invasion. Finlay BB,  Heffron F, Falkow S.  Science.  1989; 243 (4893): 940-3
• Coordinate regulation and sensory transduction in the control of bacterial virulence. Miller JF,  Mekalanos JJ, Falkow S.  Science.  1989; 243 (4893): 916-22
• Expression of pertussis toxin correlates with pathogenesis in Bordetella species. Monack D,  Munoz JJ, Peacock MG, Black WJ, Falkow S.  J Infect Dis.  1989; 159 (2): 205-10
• Passage of Salmonella through polarized epithelial cells: role of the host and bacterium. Finlay BB,  Fry J, Rock EP, Falkow S.  J Cell Sci Suppl.  1989; 11 99-107
• The ail locus is found uniquely in Yersinia enterocolitica serotypes commonly associated with disease. Miller VL,  Farmer JJ, Hill WE, Falkow S.  Infect Immun.  1989; 57 (1): 121-31
• Molecular Koch's postulates applied to microbial pathogenicity. Falkow S,  Rev Infect Dis.  1988 Jul-Aug; 10 Suppl 2 S274-6
• Penetration of Salmonella through a polarized Madin-Darby canine kidney epithelial cell monolayer. Finlay BB,  Gumbiner B, Falkow S.  J Cell Biol.  1988; 107 (1): 221-30
• Comparison of the invasion strategies used by Salmonella cholerae-suis, Shigella flexneri and Yersinia enterocolitica to enter cultured animal cells: endosome acidification is not required for bacterial invasion or intracellular replication. Finlay BB,  Falkow S.  Biochimie.  1988; 70 (8): 1089-99
• Purification, characterization, and pathogenicity of Moraxella bovis pili. Ruehl WW,  Marrs CF, Fernandez R, Falkow S, Schoolnik GK.  J Exp Med.  1988; 168 (3): 983-1002
• Virulence factors associated with Salmonella species. Finlay BB,  Falkow S.  Microbiol Sci.  1988; 5 (11): 324-8
• Identification of a Yersinia pestis-specific DNA probe with potential for use in plague surveillance. McDonough KA,  Schwan TG, Thomas RE, Falkow S.  J Clin Microbiol.  1988; 26 (12): 2515-9
• Identification and characterization of TnphoA mutants of Salmonella that are unable to pass through a polarized MDCK epithelial cell monolayer. Finlay BB,  Starnbach MN, Francis CL, Stocker BA, Chatfield S, Dougan G, Falkow S.  Mol Microbiol.  1988; 2 (6): 757-66
• Identification of regions on a 230-kilobase plasmid from enteroinvasive Escherichia coli that are required for entry into HEp-2 cells. Small PL,  Falkow S.  Infect Immun.  1988; 56 (1): 225-9
• Using knowledge of virulence factors to select or design organisms with low risk of pathogenicity. Falkow S,  Basic Life Sci.  1988; 45 121-6
• Genetic analysis of an Escherichia coli urease locus: evidence of DNA rearrangement. Collins CM,  Falkow S.  J Bacteriol.  1988; 170 (3): 1041-5
• Genetic analysis of a region of the Bordetella pertussis chromosome encoding filamentous hemagglutinin and the pleiotropic regulatory locus vir. Stibitz S,  Weiss AA, Falkow S.  J Bacteriol.  1988; 170 (7): 2904-13
• Model for invasion of human tissue culture cells by Neisseria gonorrhoeae. Shaw JH,  Falkow S.  Infect Immun.  1988; 56 (6): 1625-32
• Evidence for two genetic loci in Yersinia enterocolitica that can promote invasion of epithelial cells. Miller VL,  Falkow S.  Infect Immun.  1988; 56 (5): 1242-8
• ADP-ribosyltransferase activity of pertussis toxin and immunomodulation by Bordetella pertussis. Black WJ,  Munoz JJ, Peacock MG, Schad PA, Cowell JL, Burchall JJ, Lim M, Kent A, Steinman L, Falkow S.  Science.  1988; 240 (4852): 656-9
• A molecular strategy for the study of bacterial invasion. Falkow S,  Small P, Isberg R, Hayes SF, Corwin D.  Rev Infect Dis.  1987 Sep-Oct; 9 Suppl 5 S450-5
• Construction and characterization of Bordetella pertussis toxin mutants. Black WJ,  Falkow S.  Infect Immun.  1987; 55 (10): 2465-70
• Development of a tissue culture model for gonococcal invasion. Shaw JH,  Hayes F, Brooks GF, Falkow S.  Antonie Van Leeuwenhoek.  1987; 53 (6): 485-91
• Genetic analysis of cell invasiveness by Yersinia pseudotuberculosis. Isberg RR,  Falkow S.  Ann Inst Pasteur Microbiol.  1986 May-Jun; 137A (3): 308-10