Maurice L. Druzin

Clinical Focus

• Obstetrics
• Maternal and Fetal Medicine

Administrative Appointments

• MQIP Hemorrhage Task Force Committee Meeting, CMQCC , (2008– present )
• Pregnancy Related Mortality Review, CMQCC , (2007– present )
• California Maternal Quality Care Collaborative, CMQCC , (2007– present )
• Co-Director, Johnson Center for Pregnancy and Newborn Services, Lucile Salter Packard Children's Hospital , (1997– present )
• Director, OBGYN Residency Training Program , (2001– present )
• Associate Dean for Academic Affairs, Stanford University School of Medicine , (2001– present )
• Director, Maternal-Fetal Medicine Fellowship Program , (2001– present )
• Vice Chair, Stanford University School of Medicine - Obstetrics & Gynecology , (2005– present )

Honors and Awards

• APGO/Ortho-McNeil Faculty Development Award, APGO (2007)
• APGO/Martin L. Stone, MD Fund, Advancement of Medical Education in Obstetrics and Gynecology, APGO (2005)
• The Franklin G. Ebaugh, Jr. Award for Advising Medical Students, Stanford University (2009)

Professional Education

• Board Certification: Maternal and Fetal Medicine, American Board of Obstetrics and Gynecology (1981)
• Board Certification: Obstetrics and Gynecology, American Board of Obstetrics and Gynecology (1980)
• LAC & USC Medical Center (1979) CA
• University of Colorado Health Science Center (1977) CO
• University of Colorado Health Science Center (1976) CO
• Coronation Hospital (1971)
• University of Witwatersrand (1970) South Africa

Postdoctoral Advisees

• Mara Greenberg, Elizabeth Langen, Joyce Sung

Graduate & Fellowship Program Affiliations

• Obstetrics and Gynecology

Industry Relationships

Stanford is committed to ethical and transparent interactions with our industry partners. It is our policy to disclose payments of $5,000 or more, equity valued at $5,000 or more in a publicly traded company, or any equity in a privately held company, to physicians and scientists employed by Stanford University from companies or other commercial entities with which they interact as part of their professional activities. 

• Consulting: Alere Health Systems, Arch Speciality insurance Company, Hall, Pringle and Schoonveld, LLC, Kaiser Foundation Health Plan

Research Interests

Antepartum and intrapartum fetal monitoring
Prenatal diagnosis
Medical complications of pregnancy, particularly: SLE, hypertension, diabetes, malignancy

A. Medical Complications of Pregnancy Especially:
1. Pregnancies complicated by S.L.E. and the Antiphospholipid Syndrome
2. Recurrent Fetal Loss
3. Diabetes and Pregnancy
4. Prematurity
5. Hypertension

B. Antepartum Fetal Evaluation and Intrapartum Fetal Evaluation by Means of Electronic Fetal Monitoring.

Clinical Trials

• Comparison of ampicillin / sulbactam vs. ampicillin / gentamicin for treatment of intrapartum chorioamnionitis: a randomized controlled trial Recruiting
• Prophylactic Enoxaparin dosing for prevention of venous thromboembolism in pregnancy – a prospective randomized trial Recruiting
• Progesterone for Maintenance Tocolysis: A Randomized Placebo Controlled Trial Not yet recruiting

Publications

• The use of vibro-acoustic stimulation during the abnormal/equivocal biophysical profile Druzin ML,,  Inglis SR, Wagner WE, Kogut E..  Obstet Gynecol. 
• Acute liver failure at 26 weeks' gestation in a patient with sickle cell disease. Greenberg M,  Daugherty TJ, Elihu A, Sharaf R, Concepcion W, Druzin M, Esquivel CO.  Liver Transpl.  2009; 15 (10): 1236-41
• Maintenance nifedipine tocolysis compared with placebo: a randomized controlled trial. Lyell DJ,  Pullen KM, Mannan J, Chitkara U, Druzin ML, Caughey AB, El-Sayed YY.  Obstet Gynecol.  2008; 112 (6): 1221-6
• Urinalysis vs urine protein-creatinine ratio to predict significant proteinuria in pregnancy. Dwyer BK,  Gorman M, Carroll IR, Druzin M.  J Perinatol.  2008; 28 (7): 461-7
• Editorial summary of symposium on hypertensive disorders of pregnancy. Druzin ML,  Charles B, Johnson AL.  Curr Opin Obstet Gynecol.  2008; 20 (2): 91
• VEGF blockade inhibits angiogenesis and reepithelialization of endometrium. Fan X,  Krieg S, Kuo CJ, Wiegand SJ, Rabinovitch M, Druzin ML, Brenner RM, Giudice LC, Nayak NR.  FASEB J.  2008; 22 (10): 3571-80
• Perinatal outcomes among Asian-white interracial couples. Nystrom MJ,  Caughey AB, Lyell DJ, Druzin ML, El-Sayed YY.  Am J Obstet Gynecol.  2008; 199 (4): 385.e1-5
• Use of simulation based team training for obstetric crises in resident education. Daniels K,  Lipman S, Harney K, Arafeh J, Druzin M.  Simul Healthc.  2008; 3 (3): 154-60
• How we treat: management of life-threatening primary postpartum hemorrhage with a standardized massive transfusion protocol. Burtelow M,  Riley E, Druzin M, Fontaine M, Viele M, Goodnough LT.  Transfusion.  2007; 47 (9): 1564-72
• Randomized comparison of intravenous terbutaline vs nitroglycerin for acute intrapartum fetal resuscitation. Pullen KM,  Riley ET, Waller SA, Taylor L, Caughey AB, Druzin ML, El-Sayed YY.  Am J Obstet Gynecol.  2007; 197 (4): 414.e1-6
• Use of a community mobile health van to increase early access to prenatal care. Edgerley LP,  El-Sayed YY, Druzin ML, Kiernan M, Daniels KI.  Matern Child Health J.  2007; 11 (3): 235-9
• Magnesium sulfate compared with nifedipine for acute tocolysis of preterm labor: a randomized controlled trial. Lyell DJ,  Pullen K, Campbell L, Ching S, Druzin ML, Chitkara U, Burrs D, Caughey AB, El-Sayed YY.  Obstet Gynecol.  2007; 110 (1): 61-7
• Perinatal outcomes after successful and failed trials of labor after cesarean delivery. El-Sayed YY,  Watkins MM, Fix M, Druzin ML, Pullen KM, Caughey AB.  Am J Obstet Gynecol.  2007; 196 (6): 583.e1-5; discussion 583.e5
• Gene expression patterns in human placenta. Sood R,  Zehnder JL, Druzin ML, Brown PO.  Proc Natl Acad Sci U S A.  2006; 103 (14): 5478-83
• Effect of L-arginine therapy on the glomerular injury of preeclampsia: a randomized controlled trial. Hladunewich MA,  Derby GC, Lafayette RA, Blouch KL, Druzin ML, Myers BD.  Obstet Gynecol.  2006; 107 (4): 886-95
• Cesarean delivery on maternal request: wise use of finite resources? A view from the trenches. Druzin ML,  El-Sayed YY.  Semin Perinatol.  2006; 30 (5): 305-8
• Outcome of pregnancies complicated by systemic sclerosis and mixed connective tissue disease. Chung L,  Flyckt RL, Colón I, Shah AA, Druzin M, Chakravarty EF.  Lupus.  2006; 15 (9): 595-9
• Comparison of rapid intrapartum screening methods for group B streptococcal vaginal colonization. Aziz N,  Baron EJ, D'Souza H, Nourbakhsh M, Druzin ML, Benitz WE.  J Matern Fetal Neonatal Med.  2005; 18 (4): 225-9
• Prospective randomized clinical trial of inpatient cervical ripening with stepwise oral misoprostol vs vaginal misoprostol. Colón I,  Clawson K, Hunter K, Druzin ML, Taslimi MM.  Am J Obstet Gynecol.  2005; 192 (3): 747-52
• Detection of sonographic markers of fetal aneuploidy depends on maternal and fetal characteristics. Taslimi MM,  Acosta R, Chueh J, Hudgins L, Hunter K, Druzin ML, Chitkara U.  J Ultrasound Med.  2005; 24 (6): 811-5
• Factors that predict prematurity and preeclampsia in pregnancies that are complicated by systemic lupus erythematosus. Chakravarty EF,  Colón I, Langen ES, Nix DA, El-Sayed YY, Genovese MC, Druzin ML.  Am J Obstet Gynecol.  2005; 192 (6): 1897-904
• The dynamics of glomerular filtration in the puerperium. Hladunewich MA,  Lafayette RA, Derby GC, Blouch KL, Bialek JW, Druzin ML, Deen WM, Myers BD.  Am J Physiol Renal Physiol.  2004; 286 (3): F496-503
• End tidal carbon monoxide levels are lower in women with gestational hypertension and pre-eclampsia. Kreiser D,  Baum M, Seidman DS, Fanaroff A, Shah D, Hendler I, Stevenson DK, Schiff E, Druzin ML.  J Perinatol.  2004; 24 (4): 213-7
• Cost-effectiveness of a trial of labor after previous cesarean delivery depends on the a priori chance of success. Macario A,  El-Sayed YY, Druzin ML.  Clin Obstet Gynecol.  2004; 47 (2): 378-85
• Vaginal versus ultrasound examination of fetal occiput position during the second stage of labor. Chou MR,  Kreiser D, Taslimi MM, Druzin ML, El-Sayed YY.  Am J Obstet Gynecol.  2004; 191 (2): 521-4
• Neonatal chest wall rigidity following the use of remifentanil for cesarean delivery in a patient with autoimmune hepatitis and thrombocytopenia. Carvalho B,  Mirikitani EJ, Lyell D, Evans DA, Druzin M, Riley ET.  Int J Obstet Anesth.  2004; 13 (1): 53-6
• Randomized comparison of intravenous nitroglycerin and subcutaneous terbutaline for external cephalic version under tocolysis. El-Sayed YY,  Pullen K, Riley ET, Lyell D, Druzin ML, Cohen SE, Chitkara U.  Am J Obstet Gynecol.  2004; 191 (6): 2051-5
• Prothrombin gene variants in non-Caucasians with fetal loss and intrauterine growth retardation. Schrijver I,  Lenzi TJ, Jones CD, Lay MJ, Druzin ML, Zehnder JL.  J Mol Diagn.  2003; 5 (4): 250-3
• Evaluation of a novel electronic fetal monitor simulator. Murphy AA,  Halamek LP, Lyell DJ, Druzin ML.  Stud Health Technol Inform.  2003; 94 240-4
• Training and competency assessment in electronic fetal monitoring: a national survey. Murphy AA,  Halamek LP, Lyell DJ, Druzin ML.  Obstet Gynecol.  2003; 101 (6): 1243-8
• Central nervous system lupus and pregnancy: 11-year experience at a single center. El-Sayed YY,  Lu EJ, Genovese MC, Lambert RE, Chitkara U, Druzin ML.  J Matern Fetal Neonatal Med.  2002; 12 (2): 99-103
• A longitudinal analysis of maternal serum insulin-like growth factor I (IGF-I) and total and nonphosphorylated IGF-binding protein-1 in human pregnancies complicated by intrauterine growth restriction. Bhatia S,  Faessen GH, Carland G, Balise RL, Gargosky SE, Druzin M, El-Sayed Y, Wilson DM, Giudice LC.  J Clin Endocrinol Metab.  2002; 87 (4): 1864-70
• Fetal ear length measurement: a useful predictor of aneuploidy? Chitkara U,  Lee L, Oehlert JW, Bloch DA, Holbrook RH, El-Sayed YY, Druzin ML.  Ultrasound Obstet Gynecol.  2002; 19 (2): 131-5
• Cost-effectiveness of a trial of labor after previous cesarean. Chung A,  Macario A, El-Sayed YY, Riley ET, Duncan B, Druzin ML.  Obstet Gynecol.  2001; 97 (6): 932-41
• Mask induction with sevoflurane in a parturient with severe tracheal stenosis. Ratner EF,  Cohen SE, El Sayed Y, Druzin M.  Anesthesiology.  2001; 95 (2): 553-5
• Decreased amniotic fluid index in low-risk pregnancy. Kreiser D,  el-Sayed YY, Sorem KA, Chitkara U, Holbrook RH, Druzin ML.  J Reprod Med.  2001; 46 (8): 743-6
• Ultrasonographic ear length measurement in normal second- and third-trimester fetuses. Chitkara U,  Lee L, El-Sayed YY, Holbrook RH, Bloch DA, Oehlert JW, Druzin ML.  Am J Obstet Gynecol.  2000; 183 (1): 230-4
• Preventing early-onset group B streptococcal sepsis: strategy development using decision analysis. Benitz WE,  Gould JB, Druzin ML.  Pediatrics.  1999; 103 (6): e76
• The dynamics of glomerular filtration after Caesarean section. Lafayette RA,  Malik T, Druzin M, Derby G, Myers BD.  J Am Soc Nephrol.  1999; 10 (7): 1561-5
• Antimicrobial prevention of early-onset group B streptococcal sepsis: estimates of risk reduction based on a critical literature review. Benitz WE,  Gould JB, Druzin ML.  Pediatrics.  1999; 103 (6): e78
• Risk factors for early-onset group B streptococcal sepsis: estimation of odds ratios by critical literature review. Benitz WE,  Gould JB, Druzin ML.  Pediatrics.  1999; 103 (6): e77
• Randomized comparison of intravenous nitroglycerin and magnesium sulfate for treatment of preterm labor. El-Sayed YY,  Riley ET, Holbrook RH, Cohen SE, Chitkara U, Druzin ML.  Obstet Gynecol.  1999; 93 (1): 79-83
• Diltiazem for maintenance tocolysis of preterm labor: comparison to nifedipine in a randomized trial. El-Sayed YY,  Holbrook RH, Gibson R, Chitkara U, Druzin ML, Baba D.  J Matern Fetal Med.  1998 Sep-Oct; 7 (5): 217-21
• A new therapeutic approach to the fetus with congenital complete heart block: preemptive, targeted therapy with dexamethasone. Rosenthal D,  Druzin M, Chin C, Dubin A.  Obstet Gynecol.  1998; 92 (4 Pt 2): 689-91
• Analysis of prenatal and gestational care given to women with epilepsy. Seale CG,  Morrell MJ, Nelson L, Druzin ML.  Neurology.  1998; 51 (4): 1039-45
• Nature of glomerular dysfunction in pre-eclampsia. Lafayette RA,  Druzin M, Sibley R, Derby G, Malik T, Huie P, Polhemus C, Deen WM, Myers BD.  Kidney Int.  1998; 54 (4): 1240-9
• Insulin-like growth factor binding protein-1 at the maternal-fetal interface and insulin-like growth factor-I, insulin-like growth factor-II, and insulin-like growth factor binding protein-1 in the circulation of women with severe preeclampsia. Giudice LC,  Martina NA, Crystal RA, Tazuke S, Druzin M.  Am J Obstet Gynecol.  1997; 176 (4): 751-7; discussion 757-8
• Obstetric complications in pulmonary and critical care medicine. Rizk NW,  Kalassian KG, Gilligan T, Druzin MI, Daniel DL.  Chest.  1996; 110 (3): 791-809
• Systemic lupus erythematosus and pregnancy. Druzin ML,  Van Vollenhoven RF.  Ann Med Interne (Paris).  1996; 147 (4): 265-73
• Case report: a patient with severe CNS lupus during pregnancy. Kuzis CS,  Druzin ML, Lambert RE.  Ann Med Interne (Paris).  1996; 147 (4): 274-5
• Pregnancy complicated by primary antiphospholipid antibody syndrome. Hochfeld M,  Druzin ML, Maia D, Wright J, Lambert RE, McGuire J.  Obstet Gynecol.  1994; 83 (5 Pt 2): 804-5
• Should all pregnant patients be offered prenatal diagnosis regardless of age? Druzin ML,  Chervenak F, McCullough LB, Blatman RN, Neidich JA.  Obstet Gynecol.  1993; 81 (4): 615-8
• Abnormal 1,25-dihydroxyvitamin D metabolism in preeclampsia. August P,  Marcaccio B, Gertner JM, Druzin ML, Resnick LM, Laragh JH.  Am J Obstet Gynecol.  1992; 166 (4): 1295-9
• Prospective evaluation of the contraction stress and nonstress tests in the management of post-term pregnancy. Druzin ML,  Karver ML, Wagner W, Hutson JM, Waltner A, Kogut E.  Surg Gynecol Obstet.  1992; 174 (6): 507-12
• Condition specific antepartum testing - Sytemic lupus erythematosus and associated serologic abnormaliities Druzin ML,,  Adams D, Edersheim T, Bond A, Kogut E..  Am J Reprod Immun.  1992;