James Lock

Clinical Focus

• Psychiatry, Child and Adolescent
• Child and Adolescent Psychiatry

Administrative Appointments

• Director, Stanford Child and Adolescent Eating Disorder Program, Divsion of Child Psychiatry, Department of Psychiatry and Behavioral Sciences , (2002– present )
• Director, Comprehensive Pediatric Care Unit, Lucile Salter Packard Children's Hospital , (1993– 2002 )

Honors and Awards

• Mid-Career Award, National Institutes of Health (2005-2010)
• Career Development Award, National Institutes Of Health (1998-2003)
• Member, Alpha Omega Alpha Medical Honor Society (1987)
• Member, Eating Disorder Research Society (1999)
• Junior Faculty Development Award, Association of Academic Psychiatrists (1998)

Professional Education

• Board Certification: Child and Adolescent Psychiatry, American Board of Psychiatry and Neurology (1994)
• Board Certification: Psychiatry, American Board of Psychiatry and Neurology (1993)
• UC Davis (1993) CA
• UCLA Medical Center (1991) CA
• UCLA Medical Center (1988) CA
• Morehouse School of Medicine (1987) GA
• MS, Stanford University Health Services Research (2000)
• Child and Adolescent Residency, UCD Department of Psychiatry Child and Adolescent Psychiatry (1993)
• Residency, UCLA Neuropsychiatric Institute General Psychiatry (1991)
• MD, Morehouse/Emory School of Medicine Medicine (1987)
• Ph.D, Emory University Philosophy (1981)
• MA, Emory University Comparative Literature (1976)
• BA, New College Philosophy (1975)

Postdoctoral Advisees

• Alison Darcy

Graduate & Fellowship Program Affiliations

• Health Services Research
• Psychiatry and Behavioral Science

Community & International Work

• Does Hospital-Based Weight Restoration Prior to Outpatient Family Therapy Improve Outcomes for Child and Adolescent Anorexia Nervosa?, Sydney, Australia More »

Research Interests

For the past 15 years I have been developing a research program for eating disorders in children and adolescents. I am an established scientist with over 200 publications including original peer reviewed articles, professional articles, book chapters, and books in the field. I have completed several NIH funded treatment studies and am currently involved as PI or Co-PI on three additonal awards all focused on treatment interventions for eating disorders. Despite the relative frequency of anorexia nervosa (prevalence estimated at 0.48-0.7% among adolescents)and bulimia nervosa (estimated prevalence 3% in adolescents), little systematic research has been conducted in effective treatments for these disorders. My work is beginning to remedy this through the development of systematic studies of these disorders, particularly for youth.

Clinical Trials

• Study of Treatment for Adolescents with Bulimia Nervosa Recruiting
• Comparison of two types of family therapy in the treatment of adolescent anorexia nervosa Recruiting
• Prevention of childhood obesity Recruiting

Publications

• Costs of remission and recovery using family therapy for adolescent anorexia nervosa: a descriptive report. Lock J,  Couturier J, Agras WS.  Eat Disord.  2008 Jul-Sep; 16 (4): 322-30
• Predictors and moderators of outcome in family-based treatment for adolescent bulimia nervosa. Le Grange D,  Crosby RD, Lock J.  J Am Acad Child Adolesc Psychiatry.  2008; 47 (4): 464-70
• Classification of child and adolescent eating disturbances. Workgroup for Classification of Eating Disorders in Children and Adolescents (WCEDCA). Bravender T,  Bryant-Waugh R, Herzog D, Katzman D, Kreipe RD, Lask B, Le Grange D, Lock J, Loeb K, Madden S, Nicholls D, O'Toole J, Pinhas L, Rome E, Sokol-Burger M, Wallen U, Zucker N.  Int J Eat Disord.  2007; 40 Suppl S117-22
• Is family therapy useful for treating children with anorexia nervosa? Results of a case series. Lock J,  le Grange D, Forsberg S, Hewell K.  J Am Acad Child Adolesc Psychiatry.  2006; 45 (11): 1323-8
• Comparison of long-term outcomes in adolescents with anorexia nervosa treated with family therapy. Lock J,  Couturier J, Agras WS.  J Am Acad Child Adolesc Psychiatry.  2006; 45 (6): 666-72
• Role of therapeutic alliance in family therapy for adolescent anorexia nervosa. Pereira T,  Lock J, Oggins J.  Int J Eat Disord.  2006; 39 (8): 677-84
• Predictors of dropout and remission in family therapy for adolescent anorexia nervosa in a randomized clinical trial. Lock J,  Couturier J, Bryson S, Agras S.  Int J Eat Disord.  2006; 39 (8): 639-47
• How do children with eating disorders differ from adolescents with eating disorders at initial evaluation? Peebles R,  Wilson JL, Lock JD.  J Adolesc Health.  2006; 39 (6): 800-5
• The relationship between perfectionism, eating disorders and athletes: a review. Forsberg S,  Lock J.  Minerva Pediatr.  2006; 58 (6): 525-36
• Effective treatments for adolescent eating disorders Lock, J,  Gowers, S.  Journal of Mental Health.  2005; 14 599-610
• Suicidality in adolescents being treated with antidepressant medications and the black box label: position paper of the Society for Adolescent Medicine. Lock J,  Walker LR, Rickert VI, Katzman DK.  J Adolesc Health.  2005; 36 (1): 92-3
• A comparison of short- and long-term family therapy for adolescent anorexia nervosa. Lock J,  Agras WS, Bryson S, Kraemer HC.  J Am Acad Child Adolesc Psychiatry.  2005; 44 (7): 632-9
• Adjusting cognitive behavior therapy for adolescents with bulimia nervosa: results of case series. Lock J,  Am J Psychother.  2005; 59 (3): 267-81
• Family-based treatment of eating disorders. Lock J,  le Grange D.  Int J Eat Disord.  2005; 37 Suppl S64-7; discussion S87-9
• Athletics, perfectionism, and disordered eating. Hopkinson RA,  Lock J.  Eat Weight Disord.  2004; 9 (2): 99-106
• Report of the National Institutes of Health workshop on overcoming barriers to treatment research in anorexia nervosa. Agras WS,  Brandt HA, Bulik CM, Dolan-Sewell R, Fairburn CG, Halmi KA, Herzog DB, Jimerson DC, Kaplan AS, Kaye WH, le Grange D, Lock J, Mitchell JE, Rudorfer MV, Street LL, Striegel-Moore R, Vitousek KM, Walsh BT, Wilfley DE.  Int J Eat Disord.  2004; 35 (4): 509-21
• Is manualized family-based treatment for adolescent anorexia nervosa acceptable to patients? Patient satisfaction at the end of treatment Krautter, T,  Lock, J.  Journal of Family Therapy.  2004; 26 66-82
• Treatment of adolescent anorexia nervosa using family-based treatment Krautter, T,  Lock, J.  Clinical Case Series.  2004; 3 107-123
• Family-based treatment for adolescents with bulimia nervosa Le Grange, D,  Lock, J, Dymek, M.  American Journal of Psychotherapy.  2003; 57 237-250
• Assessment of eating disorders in adolescents with anorexia nervosa: self-report questionnaire versus interview. Passi VA,  Bryson SW, Lock J.  Int J Eat Disord.  2003; 33 (1): 45-54
• Children and adolescents with eating disorders: The state of the art Rome, E,  Ammerman, S, Rosen, D, Keller, R, Lock, J, Mammal, K, O'Toole, J, Rees, J, Sanders, M, Schneider, M, Sigel, E, Silber, T.  Pediatrics.  2003; 111 e98-e108
• Risk and protective factors for juvenile eating disorders. Steiner H,  Kwan W, Shaffer TG, Walker S, Miller S, Sagar A, Lock J.  Eur Child Adolesc Psychiatry.  2003; 12 Suppl 1 I38-6
• What predicts maintenance of weight for adolescents medically hospitalized for anorexia nervosa? Lock J,  Litt I.  Eat Disord.  2003; 11 (1): 1-7
• What predicts weight maintenance for adoelscents medicaly hospitalized for anorexia nervosa Lock, J,  Litt, I.  Eating Disorders.  2003; 33 1-7
• Eating attitudes in high school students in the Philippines: a preliminary study. Lorenzo CR,  Lavori PW, Lock JD.  Eat Weight Disord.  2002; 7 (3): 202-9
• Viiolence and sexual minority youth Lock, J,  Journal of School Violence.  2002; 1 77-89
• Assessing guilt in adolescents with anorexia nervosa Bergholdt, K,  Lock, J.  American Journal of Psychotherapy.  2002; 56 378-390
• Treating adolescents with eating disorders in the family context. Empirical and theoretical considerations. Lock J,  Child Adolesc Psychiatr Clin N Am.  2002; 11 (2): 331-42
• Bulimia Nervosa in adolescents: Treatment, eating pathology, and comorbidity Le Grange, D,  Lock, J.  South African Psychiatry Review.  2002; August 19-23
• The Child Abuse Potential Inventory and pregnancy outcome in expectant adolescent mothers. Zelenko MA,  Huffman LC, Brown BW, Daniels K, Lock J, Kennedy Q, Steiner H.  Child Abuse Negl.  2001; 25 (11): 1481-95
• What is the best way to treat adolescents with anorexia nervosa? Lock, J,  Eating Disorders.  2001; 9 275-278
• Associated health risks of adolescents with disordered eating: how different are they from their peers? Results from a high school survey. Lock J,  Reisel B, Steiner H.  Child Psychiatry Hum Dev.  2001; 31 (3): 249-65
• Poor adolescent expectant mothers: can we assess their potential for child abuse? Zelenko MA,  Huffman L, Lock J, Kennedy Q, Steiner H.  J Adolesc Health.  2001; 29 (4): 271-8
• Can family-based treatment of anorexia nervosa be manualized? Lock J,  Le Grange D.  J Psychother Pract Res.  2001; 10 (4): 253-61
• Perinatal complications and child abuse in a poverty sample. Zelenko M,  Lock J, Kraemer HC, Steiner H.  Child Abuse Negl.  2000; 24 (7): 939-50
• Severe somatoform disorders in adolescence: A case series using a rehabilitation model for intervention Lock, J,  Giamona, A.  Clinical Child Psychology and Psychiatry.  1999; 4 341-351
• Relationships between sexual orientation and coping styles in gay, lesbian, and bisexual youth from a community high school Lock, J,  Steiner, H.  Jounal of the Gay and Lesbian Medical Association.  1999; 3 77-82
• Gay, lesbian, and bisexual youth risks for emotional, physical, and social problems: results from a community-based survey. Lock J,  Steiner H.  J Am Acad Child Adolesc Psychiatry.  1999; 38 (3): 297-304
• How clinical pathways can be useful: An example of a clinical pathway for the treatment of anorexia nervosa in adolescents Lock, J,  Clinical Child Psychology and Psychiatry.  1999; 4 331-340
• Multi-center open label sertraline study in adolescent outpatients with major depression Ambrosini, P,  Wagner, K, Biederman, J, Glick, I, Tan, C, Elia, J, Hebeler, J, Rabinovich, H, Lock, J,.  Journal of the American Academy of Child and Adolescent Psychiatry.  1999; 38 566-572
• Psychosexual development in adolescents with chronic medical illnesses. Lock J,  Psychosomatics.  1998 Jul-Aug; 39 (4): 340-9
• Report of eroticized vomiting Lock, J,  Psychosomatic Medicine.  1998; 38 661
• Origins of homophobia in males. Psychosexual vulnerabilities and defense development. Lock J,  Kleis B.  Am J Psychother.  1998; 52 (4): 425-36
• Pregnancy and early parenthood: factors in the development of anorexia nervosa? Benton-Hardy LR,  Lock J.  Int J Eat Disord.  1998; 24 (2): 223-6
• A primer on homophobia for the child and adolescent psychiatrist. Lock J,  Kleis BN.  J Am Acad Child Adolesc Psychiatry.  1998; 37 (6): 671-3
• Treatment of homophobia in a gay male adolescent. Lock J,  Am J Psychother.  1998; 52 (2): 202-14
• Anorexia nervosa and bulimia nervosa in children and adolescents: a review of the past 10 years. Steiner H,  Lock J.  J Am Acad Child Adolesc Psychiatry.  1998; 37 (4): 352-9
• The coming out process: Develomental stages for sexual minority youth Carrion, V,  Lock, J.  Clinical Child Psychology and Psychiatry.  1997; 2 369-377
• Developmental considerations in the treatment of school-age boys with ADHD: an example of a group treatment approach. Lock J,  J Am Acad Child Adolesc Psychiatry.  1996; 35 (11): 1557-9
• Acting out and the narrative function: reconsidering Peter Blos's concept of the second individuation process. Lock J,  Am J Psychother.  1995; 49 (4): 548-57
• Psychiatric hospitalization of adolescents for conduct disorder. Lock J,  Strauss GD.  Hosp Community Psychiatry.  1994; 45 (9): 925-8
• Can experts agree on when to hospitalize adolescents? Strauss, G,  Chassin, M, Lock, J.  Journal of the American Academy of Child and Adolescent Psychiatry.  1994; 34 418-424
• Psychiatric hospitalization of adolescents for conduct disorder Lock, J,  Strauss, G.  Hospital and Community Psychiatry.  1994; 45 925-928
• The role and function of residents' organizations in psychiatric education Lock, J,  Kleis, B, Strouse, T, Jacobson, S, Yager, J, Servis, M.  Academic Psychiatry.  1993; 17 26-30
• Dissociative symptoms and disorders in patients with eating disorders McCallum, K,  Lock, J, Kulla, M, Rorty, M, Wetzel, R.  Dissociation Journal.  1992; 5 227-235
• Possible adverse interactions between fluoxetine and other psychotropics Lock, J,  Gwirtzman, H, Targ, G..  Journal of Clinical Psychopharmacology.  1990; 10 283
• Some aspects of medical hermeneutics: The role of dialectic and narrative Lock, James,  Theoretical Medicine.  1990; 41