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Key Documents

Laura C. Lazzeroni, Ph.D.

Associate Professor (Research), Psychiatry & Behavioral Science
Associate Professor (Research), Pediatrics
Member, Bio-X
Member, Cancer Center

Contact Information

Academic Offices

Personal Information
Email Lazzeroni@stanford.edu Tel (650) 723-0947

Administrative Contact
Georgie Doglietto Office Manager Email georgied@stanford.edu Tel Work 650-723-1147

Administrative Appointments

Senator, Academic Council of Stanford University , (2008– 2010 )
Senator, Stanford School of Medicine , (2003– 2006 )

Honors and Awards

Associate Editor, Statistical Applications in Genetics and Molecular Biology (2002-present)
Associate Editor, Biometrics (2003-2005)

Professional Education

PhD, UCLA Biostatistics (1994)

Graduate & Fellowship Program Affiliations

Publications

Identification of a major susceptibility locus for lethal graft-versus-host disease in MHC-matched mice. Cao TM, Lazzeroni LC, Tsai S, Pang WW, Kao A, Camp NJ, Thomas A, Shizuru JA. J Immunol. 2009; 183 (1): 462-9
Purified hematopoietic stem cell allografts reconstitute immunity superior to bone marrow. Tsao GJ, Allen JA, Logronio KA, Lazzeroni LC, Shizuru JA. Proc Natl Acad Sci U S A. 2009; 106 (9): 3288-93
FKBP5 polymorphisms and antidepressant response in geriatric depression. Sarginson JE, Lazzeroni LC, Ryan HS, Schatzberg AF, Murphy GM. Am J Med Genet B Neuropsychiatr Genet. 2009;
Pharmacogenetic effect of an endothelin-1 haplotype on response to bucindolol therapy in chronic heart failure. Taylor MR, Slavov D, Humphrey K, Zhao L, Cockroft J, Zhu X, Lavori P, Bristow MR, Mestroni L, Lazzeroni LC. Pharmacogenet Genomics. 2009; 19 (1): 35-43
Gene expression profile of the PDAPP mouse model for Alzheimer's disease with and without Apolipoprotein E. Selwood SP, Parvathy S, Cordell B, Ryan HS, Oshidari F, Vincent V, Yesavage J, Lazzeroni LC, Murphy GM. Neurobiol Aging. 2009; 30 (4): 574-90
A randomized trial of computer-based reminders and audit and feedback to improve HIV screening in a primary care setting. Sundaram V, Lazzeroni LC, Douglass LR, Sanders GD, Tempio P, Owens DK. Int J STD AIDS. 2009; 20 (8): 527-33
Effect of the MTHFR C677T and A1298C polymorphisms on survival in patients with advanced CKD and ESRD: a prospective study. Jamison RL, Shih MC, Humphries DE, Guarino PD, Kaufman JS, Goldfarb DS, Warren SR, Gaziano JM, Lavori P. Am J Kidney Dis. 2009; 53 (5): 779-89
Cognitive effects of memantine in postmenopausal women at risk of dementia: a pilot study. Wroolie TE, Kenna HA, Williams KE, Powers BN, Holcomb M, Lazzeroni L, Rasgon NL. Acta Neurol Scand. 2009; 119 (3): 172-9
Physiological correlates of social avoidance behavior in children and adolescents with fragile x syndrome. Hall SS, Lightbody AA, Huffman LC, Lazzeroni LC, Reiss AL. J Am Acad Child Adolesc Psychiatry. 2009; 48 (3): 320-9
Trends in US autism research funding. Singh J, Illes J, Lazzeroni L, Hallmayer J. J Autism Dev Disord. 2009; 39 (5): 788-95
An {alpha}2C-Adrenergic Receptor Polymorphism Alters the Norepinephrine Lowering Effects and Therapeutic Response of the Beta Blocker Bucindolol in Chronic Heart Failure. Bristow MR, Murphy GA, Krause-Steinrauf H, Anderson JL, Carlquist JF, Thaneemit-Chen S, Krishnan V, Abraham WT, Lowes BD, Port JD, Davis GW, Lazzeroni LC, Robertson AD, Lavori PW, Liggett SB. Circ Heart Fail. 2009;
HIV testing of at risk patients in a large integrated health care system. Owens DK, Sundaram V, Lazzeroni LC, Douglass LR, Tempio P, Holodniy M, Sanders GD, Shadle VM, McWhorter VC, Agoncillo T, Haren N, Chavis D, Borowsky LH, Yano EM, Jensen P, Simberkoff MS, Bozzette SA. J Gen Intern Med. 2007; 22 (3): 315-20
Prevalence of HIV infection among inpatients and outpatients in Department of Veterans Affairs health care systems: implications for screening programs for HIV. Owens DK, Sundaram V, Lazzeroni LC, Douglass LR, Sanders GD, Taylor K, VanGroningen R, Shadle VM, McWhorter VC, Agoncillo T, Haren N, Nyland J, Tempio P, Khayr W, Dietzen DJ, Jensen P, Simberkoff MS, Bozzette SA, Holodniy M. Am J Public Health. 2007; 97 (12): 2173-8
Keratin variants associate with progression of fibrosis during chronic hepatitis C infection. Strnad P, Lienau TC, Tao GZ, Lazzeroni LC, Stickel F, Schuppan D, Omary MB. Hepatology. 2006; 43 (6): 1354-63
A polymorphism within a conserved beta(1)-adrenergic receptor motif alters cardiac function and beta-blocker response in human heart failure. Liggett SB, Mialet-Perez J, Thaneemit-Chen S, Weber SA, Greene SM, Hodne D, Nelson B, Morrison J, Domanski MJ, Wagoner LE, Abraham WT, Anderson JL, Carlquist JF, Krause-Steinrauf HJ, Lazzeroni LC, Port JD, Lavori PW, Bristow MR. Proc Natl Acad Sci U S A. 2006; 103 (30): 11288-93
The effect of diagnosis with HIV infection on health-related quality of Life. Honiden S, Sundaram V, Nease RF, Holodniy M, Lazzeroni LC, Zolopa A, Owens DK. Qual Life Res. 2006; 15 (1): 69-82
Cost-effectiveness of screening for HIV in the era of highly active antiretroviral therapy. Sanders GD, Bayoumi AM, Sundaram V, Bilir SP, Neukermans CP, Rydzak CE, Douglass LR, Lazzeroni LC, Holodniy M, Owens DK. N Engl J Med. 2005; 352 (6): 570-85
Accuracy, precision, and consistency of expert HIV type 1 genotype interpretation: an international comparison (The GUESS Study). Zolopa AR, Lazzeroni LC, Rinehart A, Vezinet FB, Clavel F, Collier A, Conway B, Gulick RM, Holodniy M, Perno CF, Shafer RW, Richman DD, Wainberg MA, Kuritzkes DR. Clin Infect Dis. 2005; 41 (1): 92-9
The role of a common adenosine monophosphate deaminase (AMPD)-1 polymorphism in outcomes of ischemic and nonischemic heart failure. Kolek MJ, Carlquist JF, Thaneemit-Chen S, Lazzeroni LC, Whiting BM, Horne BD, Muhlestein JB, Lavori P, Anderson JL. J Card Fail. 2005; 11 (9): 677-83
Genome-wide identification of genes conferring resistance to the anticancer agents cisplatin, oxaliplatin, and mitomycin C. Wu HI, Brown JA, Dorie MJ, Lazzeroni L, Brown JM. Cancer Res. 2004; 64 (11): 3940-8
A polymorphism in the TCF7 gene, C883A, is associated with type 1 diabetes. Noble JA, White AM, Lazzeroni LC, Valdes AM, Mirel DB, Reynolds R, Grupe A, Aud D, Peltz G, Erlich HA. Diabetes. 2003; 52 (6): 1579-82
Association of IL4R haplotypes with type 1 diabetes. Mirel DB, Valdes AM, Lazzeroni LC, Reynolds RL, Erlich HA, Noble JA. Diabetes. 2002; 51 (11): 3336-41
Plaid models for gene expression data Lazzeroni L.C., Owen A.. Statistica Sinica. 2002;
Allele sharing and allelic association I: sib pair tests with increased power. Lazzeroni LC, Genet Epidemiol. 2002; 22 (4): 328-44
Genotype to phenotype: associations, errors and complexity. Lazzeroni LC, Karlovich CA. Trends Genet. 2002; 18 (6): 283-4
Cytomegalovirus retinitis after initiation of highly active antiretroviral therapy in HIV infected patients: natural history and clinical predictors. Lin DY, Warren JF, Lazzeroni LC, Wolitz RA, Mansour SE. Retina. 2002; 22 (3): 268-77
Gene expression patterns vary in clonal cell cultures from Rett syndrome females with eight different MECP2 mutations. Traynor J, Agarwal P, Lazzeroni L, Francke U. BMC Med Genet. 2002; 3 12
A high-resolution radiation hybrid map of the human genome draft sequence. Olivier M, Aggarwal A, Allen J, Almendras AA, Bajorek ES, Beasley EM, Brady SD, Bushard JM, Bustos VI, Chu A, Chung TR, De Witte A, Denys ME, Dominguez R, Fang NY, Foster BD, Freudenberg RW, Hadley D, Hamilton LR, Jeffrey TJ, Kelly L, Lazzeroni L, Levy MR, Lewis SC, Liu X, Lopez FJ, Louie B, Marquis JP, Martinez RA, Matsuura MK, Misherghi NS, Norton JA, Olshen A, Perkins SM, Perou AJ, Piercy C, Piercy M, Qin F, Reif T, Sheppard K, Shokoohi V, Smick GA, Sun WL, Stewart EA, Fernando J, Tejeda, Tran NM, Trejo T, Vo NT, Yan SC, Zierten DL, Zhao S, Sachidanandam R, Trask BJ, Myers RM, Cox DR. Science. 2001; 291 (5507): 1298-302
A chronology of fine-scale gene mapping by linkage disequilibrium. Lazzeroni LC, Stat Methods Med Res. 2001; 10 (1): 57-76
Statistical refinement of primer design parameters. Beasley EM, Myers RM, Cox DR, Lazzeroni LC. PCR Applications: Protocols for Functional Genomics. 1999;
A conditional inference framework for extending the transmission/disequilibrium test. Lazzeroni LC, Lange K. Hum Hered. 1998 Mar-Apr; 48 (2): 67-81
Linkage disequilibrium and gene mapping: an empirical least-squares approach. Lazzeroni LC, Am J Hum Genet. 1998; 62 (1): 159-70
Random-effects models for smoothing post-stratification weights Lazzeroni LC, Little RJA. Journal of Official Statistics. 1998; 14 61-78
Markov chains for Monte Carlo tests of genetic equilibrium Lazzeroni L.C., Lange K.. Annals of Statistics. 1997;
In vivo sequence diversity of the protease of human immunodeficiency virus type 1: presence of protease inhibitor-resistant variants in untreated subjects. Lech WJ, Wang G, Yang YL, Chee Y, Dorman K, McCrae D, Lazzeroni LC, Erickson JW, Sinsheimer JS, Kaplan AH. J Virol. 1996; 70 (3): 2038-43
Individual variation in recombination among human males. Yu J, Lazzeroni L, Qin J, Huang MM, Navidi W, Erlich H, Arnheim N. Am J Hum Genet. 1996; 59 (6): 1186-92
Multipoint linkage map of the human pseudoautosomal region, based on single-sperm typing: do double crossovers occur during male meiosis? Schmitt K, Lazzeroni LC, Foote S, Vollrath D, Fisher EM, Goradia TM, Lange K, Page DC, Arnheim N. Am J Hum Genet. 1994; 55 (3): 423-30
Multipoint mapping calculations for sperm-typing data. Lazzeroni LC, Arnheim N, Schmitt K, Lange K. Am J Hum Genet. 1994; 55 (3): 431-6
Robustness of multiple-imputation techniques to model misspecification Lazzeroni LC, Schenker N, Taylor JMG. Proc. Survey Research Methods Section, ASA. 1990; 260-265