NIH Biosketch available OnlineDaniel Bernstein
- Professor, Pediatrics - Cardiology
- Member, Cancer Center
Contact Information
- Clinical Offices
Pediatric Heart Center 725 Welch Rd MC 5912 Palo Alto, CA 94304-1601 Telephone Work (650) 721-2121 Fax (650) 725-8343
- Academic Offices
Personal Information Email danb@stanford.edu Tel (650) 723-7913Administrative Contact Kari Costa Administrative Assistant Email KCosta@stanford.eduNot for medical emergencies or patient use
Clinical Focus
- Pediatric Cardiology
- Pediatric Heart Transplantation
- Pediatric Heart Failure
Administrative Appointments
- Director, Children's Heart Center, Packard Children's Hospital at Stanford , (2001– present )
Honors and Awards
- Alfred Woodley Salter and Mabel G. Salter Endowed Professor of Pediatrics, Stanford University (April 2004-present)
Professional Education
- Board Certification: Pediatric Cardiology, American Board of Pediatrics (1985)
- UCSF Medical Center (1986) CA
- Board Certification: Pediatrics, American Board of Pediatrics (1984)
- Albert Einstein College of Medicine (1983) NY
- Montefiore Medical Center (1982) NY
- Montefiore Medical Center (1979) NY
- New York University School of Medicine (1978) NY
Postdoctoral Advisees
Web Site Links
Research Interests
We are interested in the role of the sympathetic nervous system and its cellular components (adrenergic receptors, G proteins) in regulating cardiac development and function. We are also interested in developing tools for examination of cardiovascular physiologic parameters in transgenic and targeted gene disruption mouse models of cardiovascular disease. Specific projects underway in our lab include:
1. Evaluation of the role of beta1 and beta2 adrenergic receptor subtypes in regulating cardiac structure and function by producing mice with targeted gene disruption of these receptors.
2. Evaluation of the role of crosstalk between beta receptors and other signaling pathways (MAPK,Akt,PKC) in regulating cardiac structure and function.
3. Role of beta receptors in regulation of intracellular and intramitochondrial calcium.
4. Role of beta receptors in adriamycin cardiotoxicity.
5. Exercise physiology in the mouse
6. Gene microarray analysis of cardiomyopathy models.
We also are interested in clinical cardiac transplantation in children, specifically:
1. The application of gene microarray methods of cardiac allograft rejection in pediatric patients.
2. Assessment of new techniques of immunosuppression in children.
3. Long-term complications in pediatric heart transplant patients.
Clinical Trials
- B-Receptor Signaling in Cardiomyopathy Recruiting
Publications
- Vasc Med. 2009; (3): 249-57
- Am J Physiol Heart Circ Physiol. 2009; (5): H1904-13
- Transplantation. 2009; (12): 1801-6
- Circ Heart Fail. 2009; (6): 591-598
- Transplantation. 2008; (11): 1632-9
- Am J Physiol Heart Circ Physiol. 2008; (3): H1351-H1368
- Pediatr Transplant. 2008; (4): 442-6
- Pediatr Res. 2008; (5): 576-83
- J Heart Lung Transplant. 2007; (12): 1270-80
- Transplantation. 2006; (12): 1774-80
- Circulation. 2006; (4): 273-80
- J Perinatol. 2006; (4): 237-42
- J Heart Lung Transplant. 2006; (3): 261-70
- J Mol Cell Cardiol. 2006; (3): 375-83
- Am J Physiol Heart Circ Physiol. 2006; (1): H192-9
- Semin Pediatr Surg. 2006; (3): 188-98
- Circ Res. 2005; (6): 596-604
- Transplantation. 2005; (4): 477-81
- Am J Physiol Heart Circ Physiol. 2005; (6): H2441-9
- J Heart Lung Transplant. 2005; (6): 769-73
- FASEB J. 2005; (8): 983-5
- Cardiovasc Res. 2005; (1): 73-82
- Paediatr Drugs. 2005; (6): 391-6
- Physiol Genomics. 2004; (1): 93-105
- J Appl Physiol. 2004; (5): 1686-92
- Pediatr Res. 2004; (2): 177-83
- J Heart Lung Transplant. 2004; (3): 323-9
- J Heart Lung Transplant. 2004; (2): 178-85
- J Heart Lung Transplant. 2004; (12): 1313-33
- J Mol Cell Cardiol. 2004; (6): 1159-70
- Physiol Genomics. 2003; (3): 217-26
- J Heart Lung Transplant. 2002; (11): 1213-7
- Am J Physiol Heart Circ Physiol. 2002; (5): H1838-45
- Trends Cardiovasc Med. 2002; (7): 287-94
- J Heart Lung Transplant. 2002; (6): 667-73
- Pediatrics. 2002; (1): 1-7
- Am J Cardiol. 2001; (7): 809-10
- J Heart Lung Transplant. 2001; (2): 230
- J Appl Physiol. 2001; (3): 933-8
- Pediatr Transplant. 2000; (3): 193-9
- J Heart Lung Transplant. 2000; (8): 751-5
- J Pediatr. 2000; (2): 238-42
- Pediatr Transplant. 1999; (4): 309-14
- J Heart Lung Transplant. 1999; (8): 781-5
- Mol Pharmacol. 1999; (1): 154-61
- J Biol Chem. 1999; (24): 16694-700
- Pediatr Res. 1999; (5 Pt 1): 613-4
- Am J Physiol. 1999; (4 Pt 2): H1346-54
- Am J Physiol. 1999; (4 Pt 2): H1172-7
- Circulation. 1998; (4): 369-74
- Am J Physiol. 1998; (4 Pt 2): H1184-93
- J Pediatr Surg. 1998; (4): 655-6
- Adv Pharmacol. 1998; 499-501
- Am J Physiol. 1997; (2 Pt 2): H1053-61
- Pediatr Res. 1997; (1): 51-6
- Proc Natl Acad Sci U S A. 1996; (14): 7375-80
- Science. 1996; (5276): 803-5
- J Pharmacol Exp Ther. 1995; (2): 937-42
- Ann Thorac Surg. 1995; (5): 1425-7
- Ann Thorac Surg. 1995; (6): 1575-7
- Circulation. 1994; (5 Pt 2): II51-5
- Circulation. 1993; (5 Pt 2): II230-7
- Biochim Biophys Acta. 1993; (3): 307-9
- Crit Care Med. 1993; (9 Suppl): S354-5
- Circ Res. 1992; (6): 1465-71
- J Thorac Cardiovasc Surg. 1992; (1): 189-94; discussion 194-5
- Ann Thorac Surg. 1992; (2): 306-10
- Pediatr Res. 1992; (3): 234-8
- J Clin Invest. 1992; (4): 1128-32
- Circulation. 1992; (4): 1433-9
- Am J Physiol. 1991; (4 Pt 2): H1135-40
- Pediatrics. 1991; (2): 203-14
- Pediatr Res. 1991; (4 Pt 1): 323-8
- J Thorac Cardiovasc Surg. 1991; (6): 1082-7
- J Clin Invest. 1990; (1): 68-74
- Adv Pediatr. 1990; 413-39
- J Heart Transplant. 1989 Jan-Feb; (1): 20-6