Les Dorfman

Clinical Focus

• Neurology
• Multiple Sclerosis
• Neuromuscular Diseases
• Clinical Neurophysiology
• Electromyography
• Evoked Potentials
• EMG
• Nerve Conduction
• Myelopathy
• Optic Neuritis
• Neuropathy
• Myopathy
• Neuromuscular Junction Diseases

Administrative Appointments

• Director, Residency Program in Clinical Neurophysiology , (1995– present )
• Director, Stanford Neurodiagnostic Laboratories , (1994– present )
• Director, SHC/LPCH Evoked Potential Laboratories , (1991– present )
• Director, SHC/LPCH Electromyography Laboratories , (1991– present )
• Director, Stanford Multiple Sclerosis Clinic , (1974– present )

Honors and Awards

• President, American Association for Electrodiagnostic Medicine (1997-98)
• President, AAEM Foundation for Research and Education (1997-98)
• Director, American Board of Electrodiagnostic Medicine (1999-2005)
• President, Association of California Neurologists (2002-04)

Professional Education

• Board Certification: Clinical Neurophysiology, American Board of Psychiatry and Neurology (1991)
• Board Certification: Neurology, American Board of Psychiatry and Neurology (1975)
• Mayo Clinic (1974) MN
• National Hospital (1974) UK England
• SUMC - Graduate Medical Education (1973) CA
• Greenwich Hospital (1970) CT
• Greenwich Hospital (1969) CT
• Albert Einstein College of Medicine (1968) NY
• BSc, McGill University Physiological Psychology (1964)
• MD, Albert Einstein Medicine (1968)

Graduate & Fellowship Program Affiliations

• Neurology and Neurol Sciences
• Neurosciences

Community & International Work

• NMSS Clinical Advisory Board, Santa Clara County More »
• ACN Board of Directors -Consultant, Sacramento More »

Research Interests

Clinical electrophysiology of the peripheral and central nervous systems, including nerve conduction velocity; electromyography (EMG); and visual, auditory and somatosensory evoked potentials. Application of digital signal processing techniques in clinical neurophysiology for diagnosis of neurological disorders and for neurological rehabilitation. Multiple sclerosis (MS) diagnosis and treatment. Implementation of new methodologies for teaching clinical neuroscience to undergraduate, graduate and medical students, residents and fellows.

Publications

• Effect of moyamoya disease on neuropsychological functioning in adults. Karzmark P,  Zeifert PD, Tan S, Dorfman LJ, Bell-Stephens TE, Steinberg GK.  Neurosurgery.  2008; 62 (5): 1048-51; discussion 1051-2
• AAEM minimonograph #47: normative data in electrodiagnostic medicine. ff. Dorfman LJ,  Robinson LR.  Muscle Nerve.  1997; 20 (1): 4-14
• Phase 1 clinical trial of chimeric monoclonal anti-CD4 antibody in multiple sclerosis. Lindsey JW,  Hodgkinson S, Mehta R, Siegel RC, Mitchell DJ, Lim M, Piercy C, Tram T, Dorfman L, Enzmann D.  Neurology.  1994; 44 (3 Pt 1): 413-9
• A comparison of turns analysis and motor unit analysis in electromyography. McGill KC,  Lau K, Dorfman LJ.  Electroencephalogr Clin Neurophysiol.  1991; 81 (1): 8-17
• Quantitative clinical electrophysiology in the evaluation of nerve injury and regeneration. Dorfman LJ,  Muscle Nerve.  1990; 13 (9): 822-8
• Polyneuropathy, ophthalmoplegia, leukoencephalopathy, and intestinal pseudo-obstruction: POLIP syndrome. Simon LT,  Horoupian DS, Dorfman LJ, Marks M, Herrick MK, Wasserstein P, Smith ME.  Ann Neurol.  1990; 28 (3): 349-60
• Triphasic behavioral response of motor units to submaximal fatiguing exercise. Dorfman LJ,  Howard JE, McGill KC.  Muscle Nerve.  1990; 13 (7): 621-8
• Motor unit firing rates and firing rate variability in the detection of neuromuscular disorders. Dorfman LJ,  Howard JE, McGill KC.  Electroencephalogr Clin Neurophysiol.  1989; 73 (3): 215-24
• AAEE minimonograph #29: automatic quantitative electromyography. Dorfman LJ,  McGill KC.  Muscle Nerve.  1988; 11 (8): 804-18
• Age effects on properties of motor unit action potentials: ADEMG analysis. Howard JE,  McGill KC, Dorfman LJ.  Ann Neurol.  1988; 24 (2): 207-13
• Influence of contractile force on properties of motor unit action potentials: ADEMG analysis. Dorfman LJ,  Howard JE, McGill KC.  J Neurol Sci.  1988; 86 (2-3): 125-36
• Properties of motor unit action potentials recorded with concentric and monopolar needle electrodes: ADEMG analysis. Howard JE,  McGill KC, Dorfman LJ.  Muscle Nerve.  1988; 11 (10): 1051-5
• Computer analysis of compound action potentials. Dorfman LJ,  Electroencephalogr Clin Neurophysiol Suppl.  1987; 39 33-7
• Evoked potentials in hysteria and malingering. Howard JE,  Dorfman LJ.  J Clin Neurophysiol.  1986; 3 (1): 39-49