Henry J. Lowe, MD

Administrative Appointments

• Director CTSA Translational Informatics Program, Stanford Center for Clinical and Translational Education and Research , (2008– present )
• Director, Stanford Center for Clinical Informatics , (2004– present )
• Chief Information Officer, Stanford University School of Medicine , (2003– present )
• Senior Associate Dean for Information Resources and Technology, Stanford University School of Medicine , (2002– present )

Honors and Awards

• Elected Fellow, American College of Medical Informatics (ACMI) (1998)
• Diplomate, American Board of Internal Medicine (1984)

Professional Education

• MB, BCH, BAO (MD), University College Dublin Medicine (1980)
• Residency, St. Elizabeth's Hospital Boston Internal Medicine (1983)
• Residency, New England Medical Center Neurology (1984)
• Fellowship, MGH, Harvard Medical School Medicine and Medical Informatics (1989)

Graduate & Fellowship Program Affiliations

• Biomedical Informatics

Web Site Links

• Stanford Center for Clinical Informatics

Research Interests

My research in the field of biomedical informatics over the past 30 years has focused on the development of novel uses of information technology and computer science to improve human health. My current interests include the Electronic Health Record (EHR), biomedical knowledge representation, Internet applications in healthcare, clinical data warehouses, clinical data and text mining, academic social networking and the use of information technology to support clinical and translational research.

Publications

• STRIDE: An Integrated Standards-Based Translational Research Informatics Platform Lowe HJ,  Ferris TA, Hernandez PM, Weber SC.  AMIA Annu Symp Proc 2009 (In Press).  2009;
• Automated Mapping of Pharmacy Orders from Two Electronic Health Record Systems to RxNorm within the STRIDE Clinical Data Warehouse Hernandez PN,  Podchiyska T, Weber SC, Ferris TA, Lowe HJ.  AMIA Annu Symp Proc 2009 (In Press).  2009;
• Using a Statistical Natural Language Parser Augmented with the UMLS Specialist Lexicon to Assign SNOMED CT Codes to Anatomic Sites and Pathologic Diagnoses in Full Text Pathology Reports Lowe HJ,  Huang Y, Regula DP.  AMIA Annu Symp Proc 2009 (In Press).  2009;
• Novel integration of hospital electronic medical records and gene expression measurements to identify genetic markers of maturation. Chen DP,  Weber SC, Constantinou PS, Ferris TA, Lowe HJ, Butte AJ.  Pac Symp Biocomput.  2008; 243-54
• A novel hybrid approach to automated negation detection in clinical radiology reports. Huang Y,  Lowe HJ.  J Am Med Inform Assoc.  2007 May-Jun; 14 (3): 304-11
• Clinical arrays of laboratory measures, or "clinarrays", built from an electronic health record enable disease subtyping by severity. Chen DP,  Weber SC, Constantinou PS, Ferris TA, Lowe HJ, Butte AJ.  AMIA Annu Symp Proc.  2007; 115-9
• Improved identification of noun phrases in clinical radiology reports using a high-performance statistical natural language parser augmented with the UMLS specialist lexicon. Huang Y,  Lowe HJ, Klein D, Cucina RJ.  J Am Med Inform Assoc.  2005 May-Jun; 12 (3): 275-85
• A grammar-based classification of negations in clinical radiology reports. Huang Y,  Lowe HJ.  AMIA Annu Symp Proc.  2005; 988
• A pilot study of contextual UMLS indexing to improve the precision of concept-based representation in XML-structured clinical radiology reports. Huang Y,  Lowe HJ, Hersh WR.  J Am Med Inform Assoc.  2003 Nov-Dec; 10 (6): 580-7
• Preparing doctors for bedside computing. Moffett SE,  Menon AS, Meites EM, Kush S, Lin EY, Grappone T, Lowe HL.  Lancet.  2003; 362 (9377): 86
• A randomized trial using computerized decision support to improve treatment of major depression in primary care. Rollman BL,  Hanusa BH, Lowe HJ, Gilbert T, Kapoor WN, Schulberg HC.  J Gen Intern Med.  2002; 17 (7): 493-503
• A proposed key escrow system for secure patient information disclosure in biomedical research databases. Ferris TA,  Garrison GM, Lowe HJ.  Proc AMIA Symp.  2002; 245-9
• Evaluation of a filmless radiology pilot--a preliminary report. Mast CG,  Caruso MA, Gadd CS, Lowe HJ.  Proc AMIA Symp.  2001; 443-7
• The electronic medical record. A randomized trial of its impact on primary care physicians' initial management of major depression [corrected]. Rollman BL,  Hanusa BH, Gilbert T, Lowe HJ, Kapoor WN, Schulberg HC.  Arch Intern Med.  2001; 161 (2): 189-97
• Selective automated indexing of findings and diagnoses in radiology reports. Hersh W,  Mailhot M, Arnott-Smith C, Lowe H.  J Biomed Inform.  2001; 34 (4): 262-273
• Defining the role of anatomic pathology images in the multimedia electronic medical record--a preliminary report. Crowley RS,  Gadd CS, Naus G, Becich M, Lowe HJ.  Proc AMIA Symp.  2000; 161-5
• Transforming the cancer center in the 21st century. Lowe HJ,  MD Comput.  1999 May-Jun; 16 (3): 40-2
• Automated semantic indexing of imaging reports to support retrieval of medical images in the multimedia electronic medical record. Lowe HJ,  Antipov I, Hersh W, Smith CA, Mailhot M.  Methods Inf Med.  1999; 38 (4-5): 303-7
• The electronic medical record: its role in disseminating depression guidelines in primary care practice. Rollman BL,  Gilbert T, Lowe HJ, Kapoor WN, Schulberg HC.  Int J Psychiatry Med.  1999; 29 (3): 267-86
• Multimedia electronic medical record systems. Lowe HJ,  Acad Med.  1999; 74 (2): 146-52
• Towards knowledge-based retrieval of medical images. The role of semantic indexing, image content representation and knowledge-based retrieval. Lowe HJ,  Antipov I, Hersh W, Smith CA.  Proc AMIA Symp.  1998; 882-6
• Information needs research in the era of the digital medical library. Lomax EC,  Lowe HJ.  Proc AMIA Symp.  1998; 658-62
• The World Wide Web: a review of an emerging internet-based technology for the distribution of biomedical information. Lowe HJ,  Lomax EC, Polonkey SE.  J Am Med Inform Assoc.  1996 Jan-Feb; 3 (1): 1-14
• The Image Engine HPCC Project. A Medical Digital Library System using Agent-Based Technology to Create an Integrated View of the Electronic Medical Record. Lowe HJ,  Walker WK, Polonkey SE, Jiang F, Vries JK, McCray A.  Advances in Digital Libraries.  1996; 45-56
• WebReport: a World Wide Web based clinical multimedia reporting system. Lowe HJ,  Antipov I, Walker WK, Polonkey SE, Naus GJ.  Proc AMIA Annu Fall Symp.  1996; 314-8
• Image Engine an Integrated Multimedia Clinical Information System Lowe HJ,  Buchanan BG, Cooper GF, Kaplan B, Vries JK.  MEDINFO.  1995; 8 (1): 421-5
• Using agent-based technology to create a cost effective, integrated, multimedia view of the electronic medical record. Lowe HJ,  Walker WK, Vries JK.  Proc Annu Symp Comput Appl Med Care.  1995; 441-4
• Building a medical multimedia database system to integrate clinical information: an application of high-performance computing and communications technology. Lowe HJ,  Buchanan BG, Cooper GF, Vries JK.  Bull Med Libr Assoc.  1995; 83 (1): 57-64
• Understanding and using the medical subject headings (MeSH) vocabulary to perform literature searches. Lowe HJ,  Barnett GO.  JAMA.  1994; 271 (14): 1103-8
• Image Engine: an object-oriented multimedia database for storing, retrieving and sharing medical images and text. Lowe HJ,  Proc Annu Symp Comput Appl Med Care.  1993; 839-43
• Evaluation of a microcomputer system for searching the MEDLINE Database Lowe HJ,  Barnett GO.  Proc Annu Symp Comput Appl Med Care.  1989; 445-447
• Mapping to MeSH - The art of trapping MeSH Equivalence from within narrative text Elkin PL,  Cimino JJ, Lowe HJ.  Proc Annu Symp Comput Appl Med Care.  1988; 185-190
• Remote Access MicroMeSH: A Microcomputer System for Searching MEDLINE Lowe HJ,  Barnett GO.  Proc Annu Symp Comput Appl Med Care.  1988; 535-539
• MicroMeSH: A Microcomputer System for Searching and Exploring the National Library Medicine's Medical Subject Headings (MeSH) Vocabulary Lowe HJ,  Barnett GO.  Proc Annu Symp Comput Appl Med Care.  1987; 717-720
• Remote Access MicroMeSH: An Enhanced Microcomputer System for Searching the MEDLINE Database Lowe HJ,  Barnett GO,Scott J.  Proc Annu Symp Comput Appl Med Care.  1986; 1009-1011
• DXPLAIN: A Computer-Based Diagnostic Knowledge Base Hupp JA,  Cimino JJ, Hoffer EP, Lowe HJ.  MEDINFO.  1986; 8 (1): 421-5