Dominique Bergmann
Academic Appointments
- Associate Professor, Biology (School of Humanities and Sciences)
- Member, Bio-X
Key Documents
Contact Information
- Academic Offices
Personal Information Email Tel (650) 736-0983
Professional Overview
Administrative Appointments
- Adjunct Staff Member, Carnegie Institution for Science, Dept. of Plant Biology (2011 - present)
- Associate Member, Institute for Stem Cell Biology and Regenerative Medicine, Stanford School of Medicine (2011 - present)
Professional Education
| PhD: | University of Colorado, Boulder, Molecular Biology (2000) |
| Postdoctoral: | Carnegie Institution, Plant Development |
Postdoctoral Advisees
Jessika Adrian, Julien Alassimone, Martin Bringmann, Chin-Min Ho, On Sun Lau, Anne Vaten
Graduate & Fellowship Program Affiliations
Internet Links
Scientific Focus
Current Research Interests
Generating the full complement of functional cell types requires coordinating the production of cells with the specification programs that distinguish one cell type from another. Asymmetric cell division, in which one cell divides to create daughter cells that differ in size, location, cellular components or fate, is extensively used in the development of animals. In development of the epidermis in the model plant Arabidopsis thaliana, the specification and distribution of stomatal guard cells also requires oriented cell divisions. By studying stomatal development, one can explore how cells choose to initiate asymmetric divisions, how cells establish an internal polarity that can be translated into an asymmetric cell division, and how cells interpret external cues to align their divisions relative to the polarity of the whole tissue. Moreover, approaching these questions in a plant system is likely to reveal new solutions to the problem of balancing the robust specification of cell types with the ability to change development in the face of injury or environmental change.
Publications
- On Fate and Flexibility in Stomatal Development. Cold Spring Harb Symp Quant Biol. 2013
- Brassinosteroid regulates stomatal development by GSK3-mediated inhibition of a MAPK pathway. Nature. 2012; (7385): 419-22
- Stomatal development: a plant's perspective on cell polarity, cell fate transitions and intercellular communication. Development. 2012; (20): 3683-92
- Sequence and function of basic helix-loop-helix proteins required for stomatal development in Arabidopsis are deeply conserved in land plants. Evol Dev. 2011 Mar-Apr; (2): 182-92
- Differentiation of Arabidopsis guard cells: analysis of the networks incorporating the basic helix-loop-helix transcription factor, FAMA. Plant Physiol. 2011; (3): 1458-72
- Generation of signaling specificity in Arabidopsis by spatially restricted buffering of ligand-receptor interactions. Plant Cell. 2011; (8): 2864-79
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