Martin S. Angst
Academic Appointments
- Professor - Med Center Line, Anesthesia
- Member, Bio-X
Key Documents
Contact Information
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Clinical Offices
Anesthesia 300 Pasteur Dr S276A MC 5117 Stanford, CA 94305 Tel Work (650) 498-5109 Fax (650) 725-8052
- Academic Offices
Personal Information EmailAlternate Contact Yuki Shamoto Division Manager of Research Email Tel Work (650) 723-9896Not for medical emergencies or patient use
Professional Overview
Clinical Focus
- Anesthesia
- Anesthesia for Liver Transplantation
- Neuroanesthesia
Professional Education
| Fellowship: | Stanford University School of Medicine CA (1996) |
| Board Certification: | Anesthesia, Swiss Board of Anesthesiologists (1993) |
| Board Certification: | Anesthesia, European Board of Anesthesiologists |
| Residency: | University of Bern - Switzerland, Switzerland (1994) |
| Residency: | Regionalspital Burgdorf, Switzerland (1990) |
| Medical Education: | Berne University School of Medicine, Switzerland (1987) |
Scientific Focus
Current Research Interests
Our laboratory's current transformative research efforts focus on studying immune health in the context of surgery and anesthesia. Our interest stems from previous work elucidating the modulation of inflammatory responses by anesthetic and analgesic drugs.
The aim of studying immunity in patients undergoing surgery is to identify immune phenotypes predictive of aversive postoperative outcomes including protracted recovery and infection. Our major working hypotheses are that 1) specific immune phenotypes will predict the risk for developing postoperative complications, 2) immune phenotyping will lead to the discovery of mechanisms aggravating or alleviating such risk, and 3) gained knowledge will allow devising immune-modulatory strategies mitigating such risk. Mass cytometry (CyTOF), proteomics, and functional ex-vivo immune assays are the major molecular tools for the systems-based numerical and functional exploration of the circulating immune system.
Clinical Trials
- Recruiting Detection of Immune Changes as a Result of Surgical Trauma in Human Subject
- Not Recruiting Heritability of Opioid Effects: A Twin Study
- Not Recruiting Effects of a Peripheral Nerve Block on Biomarkers of Pain and Inflammation
- Not Recruiting Study of Experimental Models of Pain and Inflammation.
- Not Recruiting Evaluation of Propranolol's Effect on Pain and Inflammation.
Publications
- Analgesic and sympatholytic effects of low-dose intrathecal clonidine compared with bupivacaine: a dose-response study in female volunteers. Br J Anaesth. 2013
- Changes resembling complex regional pain syndrome following surgery and immobilization. J Pain. 2013; (5): 516-24
- In reply. Anesthesiology. 2013; (1): 230-1
- Postoperative subcutaneous instillation of low-dose ketorolac but not hydromorphone reduces wound exudate concentrations of interleukin-6 and interleukin-10 and improves analgesia following cesarean delivery. J Pain. 2013; (1): 48-56
- Analgesic tolerance without demonstrable opioid-induced hyperalgesia: a double-blinded, randomized, placebo-controlled trial of sustained-release morphine for treatment of chronic nonradicular low-back pain. Pain. 2012; (8): 1583-92
- Aversive and reinforcing opioid effects: a pharmacogenomic twin study. Anesthesiology. 2012; (1): 22-37
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