Itamar Harel
Academic Appointments
- Postdoctoral Research fellow, Genetics
Key Documents
Contact Information
- Academic Offices
Personal Information Email
Professional Overview
Honors and Awards
- Damon Runyon Fellow, Damon Runyon Cancer Research Foundation (2013-2016)
Professional Education
| Bachelor of Science: | University Of The Negev (2006) |
| Master of Science: | Weizmann Institute Of Science (2008) |
| Doctor of Philosophy: | Weizmann Institute Of Science (2012) |
Stanford Advisors
| Anne Brunet: | Postdoctoral Faculty Sponsor |
Graduate & Fellowship Program Affiliations
Internet Links
Scientific Focus
Current Research Interests
The overarching goal of the Brunet lab is to understand the genetic mechanisms of aging and longevity. Aging is a highly plastic process regulated by a combination of genetic and environmental factors.
I am interested in the basic molecular components that characterize young and aged cellular states. Aging is associated with an increased onset of cancer, and I seeks to define the set of factors that can rejuvenate an aged cell, without the risk of malignant transformation. Ultimately, we might be able to design strategies to directly convert old cells from a patient into young ones, eventually developing more effective cancer therapies and prevention methods.
Publications
- Pharyngeal mesoderm regulatory network controls cardiac and head muscle morphogenesis. Proc Natl Acad Sci U S A. 2012; (46): 18839-44
- The actin regulator N-WASp is required for muscle-cell fusion in mice. Proc Natl Acad Sci U S A. 2012; (28): 11211-6
- The occipital lateral plate mesoderm is a novel source for vertebrate neck musculature. Development. 2010; (17): 2961-71
- Distinct origins and genetic programs of head muscle satellite cells. Dev Cell. 2009; (6): 822-32
- Epidermal progenitors give rise to Merkel cells during embryonic development and adult homeostasis. J Cell Biol. 2009; (1): 91-100
- The contribution of Islet1-expressing splanchnic mesoderm cells to distinct branchiomeric muscles reveals significant heterogeneity in head muscle development. Development. 2008; (4): 647-57
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