Tony Wyss-Coray
Academic Appointments
- Associate Professor (Research), Neurology & Neurological Sciences
Contact Information
- Academic
Offices
Personal Information Email
Professional Snapshot
Honors and Awards
- Zenith Award, Alzheimer's Association (2005)
- Distinguished Scholar Award, The John Douglas French Alzheimer’s Foundation (2005)
- Editor, Journal of Neuroinflammation (2004)
- Medical and Scientific Advisory Council, Alzheimer's Association of Northern California & Northern Nevada (2004)
Professional Education
| M.S.: | University of Bern, Switzerland, Microbiology (1989) |
| Ph.D.: | University of Bern, Switzerland, Immunology (1992) |
Postdoctoral Advisees
Eva Czirr , Takeshi Fukuhara , Yingbo He , Kurt Lucin , Jian Luo
Graduate & Fellowship Program Affiliations
Web Site Links
Industry Relationships
Stanford is committed to ethical and transparent interactions with our industry partners. It is our policy to disclose payments of $5,000 or more, equity valued at $5,000 or more in a publicly traded company, or any equity in a privately held company, to physicians and scientists employed by Stanford University from companies or other commercial entities with which they interact as part of their professional activities. View Full Information
| Consulting: | Satoris Inc |
| Equity: | Satoris Inc |
| Service on Board of Directors: | Satoris Inc |
Scientific Focus
Current Research Interests
Our laboratory studies the role of immune and injury responses in neurodegeneration and Alzheimer’s disease. We seek to understand how immune responses and injury pathways may modulate neurodegeneration and age-related changes in the brain. We study these pathways in vivo and in cell culture using a number of genetic and proteomic tools. We have been particularly interested in the TGF-beta signaling pathway as a major regulator of biological processes and we are developing genetic and pharmacological agents to manipulate this pathway.
Publications
- The p75 neurotrophin receptor promotes amyloid-beta(1-42)-induced neuritic dystrophy in vitro and in vivo. J Neurosci. 2009; (34): 10627-37
- Bioluminescence analysis of Smad-dependent TGF-beta signaling in live mice. Methods Mol Biol. 2009: 193-202
- Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer's disease. Proc Natl Acad Sci U S A. 2009; (29): 12145-50
- Bioactive TGF-beta can associate with lipoproteins and is enriched in those containing apolipoprotein E3. J Neurochem. 2009; (4): 1254-62
- Blood protein signature for the early diagnosis of Alzheimer disease. Arch Neurol. 2009; (2): 161-5

