Down Syndrome
Research Center

Professional Snapshot

Honors and Awards

  • Zenith Award, Alzheimer's Association (2005)
  • Distinguished Scholar Award, The John Douglas French Alzheimer’s Foundation (2005)
  • Editor, Journal of Neuroinflammation (2004)
  • Medical and Scientific Advisory Council, Alzheimer's Association of Northern California & Northern Nevada (2004)

Education & Community

Professional Education

  • M.S., University of Bern, Switzerland, Microbiology (1989)
  • Ph.D., University of Bern, Switzerland, Immunology (1992)

Graduate & Fellowship Program Affiliations

Scientific Focus

Research Interests

Our laboratory studies the role of immune and injury responses in neurodegeneration and Alzheimer’s disease. We seek to understand how immune responses and injury pathways may modulate neurodegeneration and age-related changes in the brain. We study these pathways in vivo and in cell culture using a number of genetic and proteomic tools. We have been particularly interested in the TGF-beta signaling pathway as a major regulator of biological processes and we are developing genetic and pharmacological agents to manipulate this pathway.

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