Brian Feldman

Clinical Focus

• Pediatric Endocrinology

Honors and Awards

• Clinical Scientist Research Career Development Award, NIH/ NIDDK (2006-2011)
• Clinical Scholar Award, Lawson Wilkins Pediatric Endocrinology Society (2007)
• Young Investigator Award, Society for Pediatric Research (2008)

Professional Education

Postdoctoral Advisees

Maria Jose Da Silva Teixeira Costa

Research Interests

The overall goal of our research is to understand on both a molecular and systemic level how hormones regulate stem cell fate decisions and the role these pathways play in both physiology and disease. We use molecular biology and in vivo models to elucidate mechanisms of regulating cell fate determination by the endocrine system. Understanding these processes has profound and broad implications for both science and health.

Publications

• Glucocorticoid regulation of the circadian clock modulates glucose homeostasis. So AY, Bernal TU, Pillsbury ML, Yamamoto KR, Feldman BJ. Proc Natl Acad Sci U S A. 2009; 106 (41): 17582-7
• Glucocorticoids influence on mesenchymal stem cells and implications for metabolic disease. Feldman BJ, Pediatr Res. 2009; 65 (2): 249-51
• Myostatin modulates adipogenesis to generate adipocytes with favorable metabolic effects. Feldman BJ, Streeper RS, Farese RV, Yamamoto KR. Proc Natl Acad Sci U S A. 2006; 103 (42): 15675-80
• Nephrogenic syndrome of inappropriate antidiuresis. Feldman BJ, Rosenthal SM, Vargas GA, Fenwick RG, Huang EA, Matsuda-Abedini M, Lustig RH, Mathias RS, Portale AA, Miller WL, Gitelman SE. N Engl J Med. 2005; 352 (18): 1884-90
• The development of androgen-independent prostate cancer. Feldman BJ, Feldman D. Nat Rev Cancer. 2001; 1 (1): 34-45