{"result":[{"lastName":"Garcia","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Radiation Oncology"}],"primaryAppointment":"Postdoctoral Research fellow, Radiation Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=37082&type=small&showNoImage","displayName":"Patty Garcia","firstName":"Patty","href":"http://med.stanford.edu/profiles/Patty_Garcia","researchInterest":""},{"lastName":"Cleary","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Pediatrics"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4506&type=small&showNoImage","displayName":"Michael Cleary","firstName":"Michael","href":"http://med.stanford.edu/profiles/Michael_Cleary","researchInterest":"The role of oncoproteins in cancer and development; molecular and cellular biology of hematologic malignancies; targeted molecular therapies of cancer."},{"lastName":"Hu","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Obstetrics & Gynecology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Obstetrics & Gynecology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10405&type=small&showNoImage","displayName":"Mickey Hu","firstName":"Mickey","href":"http://med.stanford.edu/profiles/Mickey_Hu","researchInterest":""},{"lastName":"Giaccia","clinicalFocus":[],"appointments":[{"appointment":"Professor,Radiation Oncology - Radiation and Cancer Biology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor (By courtesy),Obstetrics & Gynecology"},{"appointment":"Professor (By courtesy),Surgery"}],"primaryAppointment":"Professor,Radiation Oncology - Radiation and Cancer Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4141&type=small&showNoImage","displayName":"Amato J. Giaccia","firstName":"Amato","href":"http://med.stanford.edu/profiles/Amato_Giaccia","researchInterest":"During the last five years, we have identified several small molecules that kill VHL deficient renal cancer cells through a synthetic lethal screening approach. Another major interest of my laboratory is in identifying hypoxia-induced genes involved in invasion and metastases. We are also investigating how hypoxia regulates gene expression epigenetically."},{"lastName":"Wong","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurosurgery"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Neurosurgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7143&type=small&showNoImage","displayName":"Albert J. Wong, M.D.","firstName":"Albert","href":"http://med.stanford.edu/profiles/Albert_Wong","researchInterest":"Our goal is to define targets for cancer therapeutics by identifying alterations in signal transduction proteins. We first identified a naturally occurring  mutant EGF receptor (EGFRvIII) and then delineated its unique signal transduction pathway. This work led to the identification of Gab1 followed by the discovery that JNK is constitutively active in tumors. We intiated using altered proteins as the target for vaccination, where an EGFRvIII based vaccine appears to be highly effective."},{"lastName":"Duque Afonso","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pathology"}],"primaryAppointment":"Postdoctoral Research fellow, Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=29334&type=small&showNoImage","displayName":"Atilio Jesus Duque-Afonso","firstName":"Atilio","href":"http://med.stanford.edu/profiles/Atilio_Duque Afonso","researchInterest":""},{"lastName":"Longo","clinicalFocus":[{"focus":"Neurology"},{"focus":"Alzheimer's Disease"},{"focus":"Huntington Disease"}],"appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"}],"primaryAppointment":"Professor,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7249&type=small&showNoImage","displayName":"Frank M. Longo, M.D., Ph.D.","firstName":"Frank","href":"http://med.stanford.edu/profiles/Frank_Longo","researchInterest":"Clinical interests include Alzheimer\u0092s disease and Huntington\u0092s disease and the development of effective therapeutics for these disorders. Laboratory interests encompass the elucidation of signaling mechanisms relevant to neurodegenerative disorders and the development of novel small molecule approaches for the treatment of neurodegenerative and other neurological disorders."},{"lastName":"Graef","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Pathology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7247&type=small&showNoImage","displayName":"Isabella Graef","firstName":"Isabella","href":"http://med.stanford.edu/profiles/Isabella_Graef","researchInterest":"We are interested in addressing questions in neuronal development and function by a combination of genetic, cell biological, biochemical and chemical approaches. \r\nThe main focus of our lab is centered around two topics: 1) the interface of signaling and gene regulation in neuronal development, with a focus on calcineurin-NFAT signaling; 2) the development of small molecules, which interfere with protein-protein interactions underlying neurodegenerative diseases."},{"lastName":"Arber","clinicalFocus":[{"focus":"Anatomic/Clinical Pathology"},{"focus":"Hematopathology"},{"focus":"Pathology"}],"appointments":[{"appointment":"Professor - Med Center Line,Pathology"}],"primaryAppointment":"Professor - Med Center Line,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3925&type=small&showNoImage","displayName":"Daniel A. Arber, M.D.","firstName":"Daniel","href":"http://med.stanford.edu/profiles/Daniel_Arber","researchInterest":"I study molecular genetic and immunophenotypic changes in human hematopoietic neoplasms. These include acute and chronic leukemias, lymphoma, and splenic tumors."},{"lastName":"Nguyen","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Stanford Cancer Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Stanford Cancer Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=24227&type=small&showNoImage","displayName":"Le Xuan Truong Nguyen","firstName":"Le Xuan Truong","href":"http://med.stanford.edu/profiles/Le Xuan Truong_Nguyen","researchInterest":""},{"lastName":"Sun","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Urology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Associate Professor,Genetics"}],"primaryAppointment":"Associate Professor,Urology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4402&type=small&showNoImage","displayName":"Zijie Sun","firstName":"Zijie","href":"http://med.stanford.edu/profiles/Zijie_Sun","researchInterest":"My lab focuses on understanding the molecular mechanism of transcription factors that govern the transformation of normal mammalian cells to a neoplastic state. We are especially interested in the action of the nuclear hormone receptors and the interactions between the receptors and other signaling pathways in related human disorders."},{"lastName":"Meyer","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4007&type=small&showNoImage","displayName":"Tobias Meyer","firstName":"Tobias","href":"http://med.stanford.edu/profiles/Tobias_Meyer","researchInterest":"CELLULAR INFORMATION PROCESSING  The main problem in signal transduction is to understand how different receptor-stimuli specifically control diverse cell functions. We are using automated microscopy, live-cell fluorescent biosensors and perturbations of predicted signaling proteins to systematically dissect signaling networks.  This allows us to identify signaling modules and to elucidate and ultimately model the flow of cellular information."},{"lastName":"Chang","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Medicine - Cardiovascular Medicine"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Associate Professor,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6387&type=small&showNoImage","displayName":"Ching-Pin Chang","firstName":"Ching-Pin","href":"http://med.stanford.edu/profiles/Ching-Pin_Chang","researchInterest":"The ultimate goal of my laboratory is to define the molecular mechanisms underlying cardiovascular development and disease and translate the bench findings to clinical applications. One objective is to understand how the major types of cardiac cells (endocardial, myocardial, epicardial and neural crest cells) interact with each other to generate heart tissues. We are interested in chromatin regulation, transcriptional and signaling events that coordinate their interactions and assembly into hea"},{"lastName":"Wei","clinicalFocus":[{"focus":"Hematology/Oncology/Stem Cell Transplant,  Pediatric"},{"focus":"Pediatric Hematology-Oncology"}],"appointments":[{"appointment":"Instructor,Pediatrics - Hematology & Oncology"}],"primaryAppointment":"Instructor,Pediatrics - Hematology & Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8537&type=small&showNoImage","displayName":"Michael Wei, MD, PhD","firstName":"Michael","href":"http://med.stanford.edu/profiles/Michael_Wei","researchInterest":""},{"lastName":"Link","clinicalFocus":[{"focus":"Hematology/Oncology/Stem Cell Transplant,  Pediatric"},{"focus":"Pediatric Hematology-Oncology"}],"appointments":[{"appointment":"Professor,Pediatrics - Hematology & Oncology"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Pediatrics - Hematology & Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4631&type=small&showNoImage","displayName":"Michael Link","firstName":"Michael","href":"http://med.stanford.edu/profiles/Michael_Link","researchInterest":"Hematology/Oncology, treatment of sarcomas of bone and soft tissue, biology of acute lymphoblastic leukemias, treatment of non-Hodgkin's lymphoma and Hodgkin's disease."},{"lastName":"Leung","clinicalFocus":[{"focus":"Dermatology"}],"appointments":[{"appointment":"Instructor,Dermatology"}],"primaryAppointment":"Instructor,Dermatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=23406&type=small&showNoImage","displayName":"Thomas Leung","firstName":"Thomas","href":"http://med.stanford.edu/profiles/Thomas_Leung","researchInterest":""},{"lastName":"Rosen","clinicalFocus":[{"focus":"Pulmonology (Lung) and Critical Care "},{"focus":"Pulmonary Disease"}],"appointments":[{"appointment":"Associate Professor,Medicine - Pulmonary & Critical Care Medicine"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Medicine - Pulmonary & Critical Care Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4245&type=small&showNoImage","displayName":"Glenn Rosen","firstName":"Glenn","href":"http://med.stanford.edu/profiles/Glenn_Rosen","researchInterest":"Our laboratory examines apoptotic and cell cycle pathways in cancer and lung disease. We have identified a novel cell cycle protein which regulates cell cycle progression in immune cells and the lung.  We are also studying signaling pathways that regulate cancer cell growth and metastasis."},{"lastName":"Berg","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Biochemistry"},{"appointment":"Professor Emeritus,SoM Dean's Office Administrative Units - Dean's Office Operations"},{"appointment":"Professor Emeritus,Biochemistry"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6263&type=small&showNoImage","displayName":"Paul Berg","firstName":"Paul","href":"http://med.stanford.edu/profiles/Paul_Berg","researchInterest":"For about 10 years until 2000, my lab's research activities were focused on the mechanism of recombinational repair of double-strand breaks in DNA. We focused our efforts on two model systems:  one involved the repair of restriction enzyme cleavages at specific mammalian chromosomal loci and the second explored the biochemical properties of purified yeast Rad51 protein, an essential catalyst for synapsing the broken ends of DNA with an intact homologue of that sequence.  We also explored the ro"},{"lastName":"Sikic","clinicalFocus":[{"focus":"Medical Oncology"},{"focus":"New Drug Studies"}],"appointments":[{"appointment":"Professor,Medicine - Oncology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4131&type=small&showNoImage","displayName":"Branimir I. Sikic, M. D.","firstName":"Branimir","href":"http://med.stanford.edu/profiles/Branimir_Sikic","researchInterest":"Research Interests: cancer pharmacology, mechanisms of resistance to anticancer drugs, regulation and function of MDR1 and tubulin genes, clinical trials of modulation of drug resistance, general oncology, Phase I trials of new drugs, gene expression profiling of cancers"},{"lastName":"Cartwright","clinicalFocus":[{"focus":"Gastroenterology"},{"focus":"Inflammatory Bowel Diseases"}],"appointments":[{"appointment":"Professor,Medicine - Gastroenterology & Hepatology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Gastroenterology & Hepatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4183&type=small&showNoImage","displayName":"Chris Cartwright, MD","firstName":"Christine","href":"http://med.stanford.edu/profiles/Christine_Cartwright","researchInterest":"Molecular mechanisms of intestinal cell growth control; function and regulation of the Src family of tyrosine kinases in normal cells, and their deregulation in cancer cells."},{"lastName":"Tibshirani","clinicalFocus":[],"appointments":[{"appointment":"Professor,Health Research & Policy - Biostatistics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Natural Sciences Cluster - Statistics"}],"primaryAppointment":"Professor,Health Research & Policy - Biostatistics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4688&type=small&showNoImage","displayName":"Robert Tibshirani","firstName":"Robert","href":"http://med.stanford.edu/profiles/Robert_Tibshirani","researchInterest":"My research is in applied statistics and biostatistics. I specialize in \u000bcomputer-intensive methods for regression and classification, bootstrap, cross-validation\u000band statistical inference, and signal and image analysis for medical diagnosis."},{"lastName":"Boyle","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"primaryAppointment":"Postdoctoral Research fellow, Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=17416&type=small&showNoImage","displayName":"Alan Boyle","firstName":"Alan","href":"http://med.stanford.edu/profiles/Alan_Boyle","researchInterest":""},{"lastName":"Kim","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=16537&type=small&showNoImage","displayName":"Taeho Kim","firstName":"Taeho","href":"http://med.stanford.edu/profiles/Taeho_Kim","researchInterest":""}]}