{"result":[{"researchInterest":"Experimental and theoretical analysis and modeling of genetic regulatory circuits, particularly bacterial regulation and with emphasis on global regulation of Caulobacter crescentus. Bioinformatic analysis of bacterial genomes, of microarray expression patterns, and cross-species genomic analysis. Techniques: gene expression microarrays, fluorescent microscopy, electron microscopy.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4403&type=small&showNoImage","href":"http://med.stanford.edu/profiles/devbio/researcher/Harley_McAdams","appointments":[{"appointment":"Professor (Research),Developmental Biology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Harley","primaryAppointment":"Professor (Research),Developmental Biology","displayName":"Harley McAdams","lastName":"McAdams"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6212&type=small&showNoImage","href":"http://med.stanford.edu/profiles/devbio/researcher/Allan_Campbell","appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"}],"clinicalFocus":[],"firstName":"Allan","primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","displayName":"Allan Campbell","lastName":"Campbell"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8857&type=small&showNoImage","href":"http://med.stanford.edu/profiles/devbio/researcher/Joseph_Lesley","appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"clinicalFocus":[],"firstName":"Joseph","primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","displayName":"Joseph Lesley","lastName":"Lesley"},{"researchInterest":"We study the functional and structural signals that govern mRNA decay and gene expression in bacteria, as well as mechanisms affecting aging and the ability of mammalian cells to support the propagation of viruses.  A small bioinformatics team within our lab has developed knowledge based systems to aid in investigations of gene expression on a genome-wide basis.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4481&type=small&showNoImage","href":"http://med.stanford.edu/profiles/devbio/researcher/Stanley_Cohen","appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Professor,Medicine"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Stanley","primaryAppointment":"Professor,Genetics","displayName":"Stanley N. Cohen, MD","lastName":"Cohen"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9747&type=small&showNoImage","href":"http://med.stanford.edu/profiles/devbio/researcher/Erin_Goley","appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"clinicalFocus":[],"firstName":"Erin","primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","displayName":"Erin Goley","lastName":"Goley"},{"researchInterest":"Our lab is interested in how bacteria monitor and coordinate cell cycle events. We are focused on identifying and characterizing signal transduction pathways used by the bacterium Bacillus subtilis to regulate cell cycle progression and development in response to chromosome status. Our goal is to understand how these pathways work mechanistically and how they contribute to normal growth, development, and genome stability.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6211&type=small&showNoImage","href":"http://med.stanford.edu/profiles/devbio/researcher/Bill_Burkholder","appointments":[{"appointment":"Assistant Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Bill","primaryAppointment":"Assistant Professor,Biology (School of Humanities and Sciences)","displayName":"Bill Burkholder","lastName":"Burkholder"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10113&type=small&showNoImage","href":"http://med.stanford.edu/profiles/devbio/researcher/Grant_Bowman","appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"clinicalFocus":[],"firstName":"Grant","primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","displayName":"Grant Bowman","lastName":"Bowman"},{"researchInterest":"1. Improvement of our newly discovered cancer prodrug regimen that permits noninvaisve visualization of drug activation. 2. Tracking tumors & cancer metastases using bacterial magnetite. 3. Molecular basis of bacterial planktonic and biofilm antibiotic resistance on Earth and under space microgravity; 4. Bioremediation.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4329&type=small&showNoImage","href":"http://med.stanford.edu/profiles/devbio/researcher/AC_Matin","appointments":[{"appointment":"Professor,Microbiology & Immunology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"AC","primaryAppointment":"Professor,Microbiology & Immunology","displayName":"AC Matin","lastName":"Matin"},{"researchInterest":"Physical chemistry/chemical physics: single-molecule imaging and spectroscopy in condensed phases; superresolution imaging of biomolecules in cells; fluorophores for cellular imaging; single-molecule biophysics; nanophotonics to produce enhanced optical fields; trapping single molecules in solution","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8121&type=small&showNoImage","href":"http://med.stanford.edu/profiles/devbio/researcher/W_Moerner","appointments":[{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"W","primaryAppointment":"Member,Bio-X","displayName":"W. E. Moerner","lastName":"Moerner"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9464&type=small&showNoImage","href":"http://med.stanford.edu/profiles/devbio/researcher/Beat_Christen","appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"clinicalFocus":[],"firstName":"Beat","primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","displayName":"Beat Christen","lastName":"Christen"},{"researchInterest":"Dr. Brown's research group uses diverse experimental and computational methods to investigate the logic and mechanisms that control a genome's expression program.  The Brown laboratory is systematically characterizing the genetic scripts that control the expression of our genes, in normal development and physiology and in diseases like cancer, with a particular focus on post-transcriptional regulation. The Brown lab also develops strategies and assays for early detection and diagnosis of cancer.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4284&type=small&showNoImage","href":"http://med.stanford.edu/profiles/devbio/researcher/Patrick_Brown","appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Patrick","primaryAppointment":"Professor,Biochemistry","displayName":"Patrick O. Brown","lastName":"Brown"},{"researchInterest":"Three-dimensional structure determination and biophysical studies of macromolecules.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4099&type=small&showNoImage","href":"http://med.stanford.edu/profiles/devbio/researcher/David_McKay","appointments":[{"appointment":"Emeritus Faculty, Acad Council,Structural Biology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"David","primaryAppointment":"Emeritus Faculty, Acad Council,Structural Biology","displayName":"David B. McKay","lastName":"McKay"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6228&type=small&showNoImage","href":"http://med.stanford.edu/profiles/devbio/researcher/Sharon_Long","appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Professor (By courtesy),Biochemistry"}],"clinicalFocus":[],"firstName":"Sharon","primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","displayName":"Sharon Long","lastName":"Long"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6252&type=small&showNoImage","href":"http://med.stanford.edu/profiles/devbio/researcher/Charles_Yanofsky","appointments":[{"appointment":"Emeritus (Active) Professor,Biology (School of Humanities and Sciences)"}],"clinicalFocus":[],"firstName":"Charles","primaryAppointment":"Emeritus (Active) Professor,Biology (School of Humanities and Sciences)","displayName":"Charles Yanofsky","lastName":"Yanofsky"},{"researchInterest":"We study the interactions between infectious bacteria and the human host cell actin cytoskeleton. Listeria monocytogenes and Shigella flexneri are unrelated food-borne bacterial pathogens that share a common mechanism of invasion and actin-dependent intercellular spread in epithelial cells. Our studies fall into three broad areas: the biochemical basis of actin-based motility by these bacteria, the biophysical mechanism of force generation, and the evolutionary origin of pathogenesis.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4432&type=small&showNoImage","href":"http://med.stanford.edu/profiles/devbio/researcher/Julie_Theriot","appointments":[{"appointment":"Associate Professor,Biochemistry"},{"appointment":"Associate Professor,Microbiology & Immunology"}],"clinicalFocus":[],"firstName":"Julie","primaryAppointment":"Associate Professor,Biochemistry","displayName":"Julie Theriot","lastName":"Theriot"},{"researchInterest":"The aim of my research is to investigate the mechanisms, frequency, and consequences of the evolutionary shifts experienced by bacteria. Some more specific areas of research include:\r\n\r\n(1)  Quantifying shifts in the strength of purifying selection and understanding the consequences of such shifts\r\n \r\n(2)  Determining whether shifts in nucleotide content are driven by shifts in mutation or shifts in selection\r\n\r\n(3)  Establishing the mechanisms of shifts in codon usage bias","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10299&type=small&showNoImage","href":"http://med.stanford.edu/profiles/devbio/researcher/Ruth_Hershberg","appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"clinicalFocus":[],"firstName":"Ruth","primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","displayName":"Ruth Hershberg","lastName":"Hershberg"},{"researchInterest":"We are using Saccharomyces cerevisiae and Human to conduct whole genome analysis projects. The yeast genome sequence has approximately 6,000 genes. We have made a set of haploid and diploid strains (21,000) containing a complete deletion of each gene. In order to facilitate whole genome analysis each deletion is molecularly tagged with a unique 20-mer DNA sequence. This sequence acts as a molecular bar code and makes it easy to identify the presence of each deletion.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4117&type=small&showNoImage","href":"http://med.stanford.edu/profiles/devbio/researcher/Ronald_Davis","appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Ronald","primaryAppointment":"Professor,Biochemistry","displayName":"Ronald Davis","lastName":"Davis"},{"researchInterest":"Dr. Falkow is no longer taking students or postdoctoral fellows in his laboratory.  \r\n\r\nPlease contact either Denise Monack (dmonack@stanford.edu) or Manuel Amieva (amieva@stanford.edu).","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4488&type=small&showNoImage","href":"http://med.stanford.edu/profiles/devbio/researcher/Stanley_Falkow","appointments":[{"appointment":"Professor,Microbiology & Immunology"},{"appointment":"Professor,Medicine"}],"clinicalFocus":[],"firstName":"Stanley","primaryAppointment":"Professor,Microbiology & Immunology","displayName":"Stanley Falkow","lastName":"Falkow"},{"researchInterest":"We study the process of cell division. Our research is focused on understanding how chromosomes are segregated during mitosis and how cells divide during cytokinesis.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6006&type=small&showNoImage","href":"http://med.stanford.edu/profiles/devbio/researcher/Aaron_Straight","appointments":[{"appointment":"Assistant Professor,Biochemistry"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Aaron","primaryAppointment":"Assistant Professor,Biochemistry","displayName":"Aaron Straight","lastName":"Straight"},{"researchInterest":"My lab is developing novel vectors and strategies for gene therapy.  We are focused on creating and using plasmid DNA vectors that integrate into the genome in a site-specific manner.  We are developing innovative gene therapies for a variety of tissues and diseases, including approaches involving stem cells.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4100&type=small&showNoImage","href":"http://med.stanford.edu/profiles/devbio/researcher/Michele_Calos","appointments":[{"appointment":"Professor,Genetics"}],"clinicalFocus":[],"firstName":"Michele","primaryAppointment":"Professor,Genetics","displayName":"Michele Calos","lastName":"Calos"},{"researchInterest":"The photochemistry and radiation chemistry of DNA, the genetic control and biochemical bases of the multiple pathways of DNA repair, and the roles of DNA repair processes in radiation and spontaneous mutagenesis. Over 190 papers have been published on these and related topics.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7014&type=small&showNoImage","href":"http://med.stanford.edu/profiles/devbio/researcher/Kendric_Smith","appointments":[{"appointment":"Emeritus Faculty, Acad Council,Radiation Oncology"}],"clinicalFocus":[],"firstName":"Kendric","primaryAppointment":"Emeritus Faculty, Acad Council,Radiation Oncology","displayName":"Kendric C. Smith","lastName":"Smith"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6209&type=small&showNoImage","href":"http://med.stanford.edu/profiles/devbio/researcher/Steven_Block","appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Professor,Applied Physics"},{"appointment":"Senior Fellow (By courtesy),Spogli Inst for Intrntl Studies"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Steven","primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","displayName":"Steven M. Block","lastName":"Block"},{"researchInterest":"Dr. Nolan's group uses high throughput single cell analysis technology of kinase driven signaling cascades to interrogate autoimmunity, cancer, virology (influenza), bacterial pathogens (Listeria and Salmonella) as well as understanding normal immune system function.  Using advanced flow cytometric techniques and computational biology approaches, we focus on high throughput drug screening, mouse models of disease in patient materials, and understanding disease processes at the single cell level.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4713&type=small&showNoImage","href":"http://med.stanford.edu/profiles/devbio/researcher/Garry_Nolan","appointments":[{"appointment":"Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Garry","primaryAppointment":"Professor,Microbiology & Immunology - Baxter Laboratory","displayName":"Garry Nolan","lastName":"Nolan"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9376&type=small&showNoImage","href":"http://med.stanford.edu/profiles/devbio/researcher/Aimee_Shen","appointments":[{"appointment":"Postdoctoral Research fellow, Pathology"}],"clinicalFocus":[],"firstName":"Aimee","primaryAppointment":"Postdoctoral Research fellow, Pathology","displayName":"Aimee Shen","lastName":"Shen"},{"researchInterest":"Our focus is on building computational models of complex biological processes, and using them to guide an experimental program. Such an approach leads to a relatively rapid identification and validation of previously unknown components and interactions. Biological systems of interest include metabolic, regulatory and signaling networks as well as cell-cell interactions. Current research involves the dynamic behavior of NF-kappaB, an important family of transcription factors.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7986&type=small&showNoImage","href":"http://med.stanford.edu/profiles/devbio/researcher/Markus_Covert","appointments":[{"appointment":"Assistant Professor,Bioengineering"},{"appointment":"Assistant Professor (By courtesy),Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Markus","primaryAppointment":"Assistant Professor,Bioengineering","displayName":"Markus Covert","lastName":"Covert"}]}