Publications
-
Itraconazole and arsenic trioxide inhibit Hedgehog pathway activation and tumor growth associated with acquired resistance to smoothened antagonists.
Kim J,
Aftab BT, Tang JY, Kim D, Lee AH, Rezaee M, Kim J, Chen B, King EM, Borodovsky A, Riggins GJ, Epstein EH, Beachy PA, Rudin CM.
Cancer Cell.
2013;
23
(1):
23-34
-
Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma.
Monje M,
Mitra SS, Freret ME, Raveh TB, Kim J, Masek M, Attema JL, Li G, Haddix T, Edwards MS, Fisher PG, Weissman IL, Rowitch DH, Vogel H, Wong AJ, Beachy PA.
Proc Natl Acad Sci U S A.
2011;
108
(11):
4453-8
-
Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder.
Shin K,
Lee J, Guo N, Kim J, Lim A, Qu L, Mysorekar IU, Beachy PA.
Nature.
2011;
472
(7341):
110-4
-
Arsenic antagonizes the Hedgehog pathway by preventing ciliary accumulation and reducing stability of the Gli2 transcriptional effector.
Kim J,
Lee JJ, Kim J, Gardner D, Beachy PA.
Proc Natl Acad Sci U S A.
2010;
107
(30):
13432-7
-
Dally-like core protein and its mammalian homologues mediate stimulatory and inhibitory effects on Hedgehog signal response.
Williams EH,
Pappano WN, Saunders AM, Kim MS, Leahy DJ, Beachy PA.
Proc Natl Acad Sci U S A.
2010;
107
(13):
5869-74
-
Genetic and biochemical definition of the Hedgehog receptor.
Zheng X,
Mann RK, Sever N, Beachy PA.
Genes Dev.
2010;
24
(1):
57-71
-
Interactions between Hedgehog proteins and their binding partners come into view.
Beachy PA,
Hymowitz SG, Lazarus RA, Leahy DJ, Siebold C.
Genes Dev.
2010;
24
(18):
2001-12
-
Itraconazole, a commonly used antifungal that inhibits Hedgehog pathway activity and cancer growth.
Kim J,
Tang JY, Gong R, Kim J, Lee JJ, Clemons KV, Chong CR, Chang KS, Fereshteh M, Gardner D, Reya T, Liu JO, Epstein EH, Stevens DA, Beachy PA.
Cancer Cell.
2010;
17
(4):
388-99
-
Patterning axon targeting of olfactory receptor neurons by coupled hedgehog signaling at two distinct steps.
Chou YH,
Zheng X, Beachy PA, Luo L.
Cell.
2010;
142
(6):
954-66
-
Gli2 trafficking links Hedgehog-dependent activation of Smoothened in the primary cilium to transcriptional activation in the nucleus.
Kim J,
Kato M, Beachy PA.
Proc Natl Acad Sci U S A.
2009;
106
(51):
21666-71
-
Identification of a cKit(+) colonic crypt base secretory cell that supports Lgr5(+) stem cells in mice.
Rothenberg ME,
Nusse Y, Kalisky T, Lee JJ, Dalerba P, Scheeren F, Lobo N, Kulkarni S, Sim S, Qian D, Beachy PA, Pasricha PJ, Quake SR, Clarke MF.
Gastroenterology.
2012;
142
(5):
1195-1205.e6
-
Scube/You activity mediates release of dually lipid-modified Hedgehog signal in soluble form.
Creanga A,
Glenn TD, Mann RK, Saunders AM, Talbot WS, Beachy PA.
Genes Dev.
2012;
26
(12):
1312-25
-
Hedgehogs, flies, Wnts and MYCs: the time has come for many things in medulloblastoma.
Monje M,
Beachy PA, Fisher PG.
J Clin Oncol.
2011;
29
(11):
1395-8
-
Structure of the protein core of the glypican Dally-like and localization of a region important for hedgehog signaling.
Kim MS,
Saunders AM, Hamaoka BY, Beachy PA, Leahy DJ.
Proc Natl Acad Sci U S A.
2011;
108
(32):
13112-7
-
Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia.
Zhao C,
Chen A, Jamieson CH, Fereshteh M, Abrahamsson A, Blum J, Kwon HY, Kim J, Chute JP, Rizzieri D, Munchhof M, VanArsdale T, Beachy PA, Reya T.
Nature.
2009;
458
(7239):
776-9
-
Truncating loss-of-function mutations of DISP1 contribute to holoprosencephaly-like microform features in humans.
Roessler E,
Ma Y, Ouspenskaia MV, Lacbawan F, Bendavid C, Dubourg C, Beachy PA, Muenke M.
Hum Genet.
2009;
125
(4):
393-400
-
Targeted inhibition of hedgehog signaling by cyclopamine prodrugs for advanced prostate cancer.
Kumar SK,
Roy I, Anchoori RK, Fazli S, Maitra A, Beachy PA, Khan SR.
Bioorg Med Chem.
2008;
16
(6):
2764-8
-
The mode of Hedgehog binding to Ihog homologues is not conserved across different phyla.
McLellan JS,
Zheng X, Hauk G, Ghirlando R, Beachy PA, Leahy DJ.
Nature.
2008;
455
(7215):
979-83
-
Disruption of the basal body compromises proteasomal function and perturbs intracellular Wnt response.
Gerdes JM,
Liu Y, Zaghloul NA, Leitch CC, Lawson SS, Kato M, Beachy PA, Beales PL, DeMartino GN, Fisher S, Badano JL, Katsanis N.
Nat Genet.
2007;
39
(11):
1350-60
-
Hedgehog signaling maintains a tumor stem cell compartment in multiple myeloma.
Peacock, C.D.,
Wang, Q., Gesell, G.S., Corcoran-Schwartz, I.M., Jones, E., Kim, J., Devereux, W.L., Rhodes, J.T., Huff, C.A., Beachy, P.A., Watkins, D.N., Matsui, W..
Proc. Natl. Acad. Sci. U.S.A..
2007:
104
4048-4053
-
Hedgehog signaling maintains a tumor stem cell compartment in multiple myeloma.
Peacock CD,
Wang Q, Gesell GS, Corcoran-Schwartz IM, Jones E, Kim J, Devereux WL, Rhodes JT, Huff CA, Beachy PA, Watkins DN, Matsui W.
Proc Natl Acad Sci U S A.
2007;
104
(10):
4048-53
-
Misexpression of Sox9 in mouse limb bud mesenchyme induces polydactyly and rescues hypodactyly mice.
Akiyama H,
Stadler HS, Martin JF, Ishii TM, Beachy PA, Nakamura T, de Crombrugghe B.
Matrix Biol.
2007;
26
(4):
224-33
-
Oxysterols are novel activators of the hedgehog signaling pathway in pluripotent mesenchymal cells.
Dwyer JR,
Sever N, Carlson M, Nelson SF, Beachy PA, Parhami F.
J Biol Chem.
2007;
282
(12):
8959-68
-
A genomewide screen for components of the RNAi pathway in Drosophila cultured cells.
Dorner S,
Lum L, Kim M, Paro R, Beachy PA, Green R.
Proc Natl Acad Sci U S A.
2006;
103
(32):
11880-5
-
Defective cerebellar response to mitogenic Hedgehog signaling in Down [corrected] syndrome mice.
Roper RJ,
Baxter LL, Saran NG, Klinedinst DK, Beachy PA, Reeves RH.
Proc Natl Acad Sci U S A.
2006;
103
(5):
1452-6
-
Defective cerebellar response to mitogenic Hedgehog signaling in Down syndrome mice.
Roper, R.J.,
Baxter, L.L., Saran, N.G., Klinedinst, D.K., Beachy, P.A., Reeves, R.H..
Proc. Natl. Acad. Sci. U.S.A..
2006:
103
1452-1456
-
Minimizing the risk of reporting false positives in large-scale RNAi screens.
Echeverri CJ,
Beachy PA, Baum B, Boutros M, Buchholz F, Chanda SK, Downward J, Ellenberg J, Fraser AG, Hacohen N, Hahn WC, Jackson AL, Kiger A, Linsley PS, Lum L, Ma Y, Mathey-Prévôt B, Root DE, Sabatini DM, Taipale J, Perrimon N, Bernards R.
Nat Methods.
2006;
3
(10):
777-9
-
Prevalence of off-target effects in Drosophila RNA interference screens.
Ma Y,
Creanga A, Lum L, Beachy PA.
Nature.
2006;
443
(7109):
359-63
-
Structure of a heparin-dependent complex of Hedgehog and Ihog.
McLellan JS,
Yao S, Zheng X, Geisbrecht BV, Ghirlando R, Beachy PA, Leahy DJ.
Proc Natl Acad Sci U S A.
2006;
103
(46):
17208-13
-
Structure of a heparin-dependent complex of Hedgehog and Ihog.
McLellan, J.S.,
Yao, S., Zheng, X., Geisbrecht, B.V., Ghirlando, R., Beachy, P.A., Leahy, D.J..
Proc. Natl. Acad. Sci. U.S.A..
2006:
103
17208-17213
-
The ihog cell-surface proteins bind Hedgehog and mediate pathway activation
Yao, S.,
Lum, L., Beachy, P.A..
Cell.
2006:
125
343-357
-
Transcriptional activation by extradenticle in the Drosophila visceral mesoderm.
Stultz BG,
Jackson DG, Mortin MA, Yang X, Beachy PA, Hursh DA.
Dev Biol.
2006;
290
(2):
482-94
-
Molecular mechanisms of Sonic hedgehog mutant effects in holoprosencephaly.
Maity T,
Fuse N, Beachy PA.
Proc Natl Acad Sci U S A.
2005;
102
(47):
17026-31
-
Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2.
Chen W,
Ren XR, Nelson CD, Barak LS, Chen JK, Beachy PA, de Sauvage F, Lefkowitz RJ.
Science.
2004;
306
(5705):
2257-60
-
Extensive phosphorylation of Smoothened in Hedgehog pathway activation.
Zhang C,
Williams EH, Guo Y, Lum L, Beachy PA.
Proc Natl Acad Sci U S A.
2004;
101
(52):
17900-7
-
Hedgehog signalling in prostate regeneration, neoplasia and metastasis.
Karhadkar SS,
Bova GS, Abdallah N, Dhara S, Gardner D, Maitra A, Isaacs JT, Berman DM, Beachy PA.
Nature.
2004;
431
(7009):
707-12
-
Mending and malignancy.
Beachy PA,
Karhadkar SS, Berman DM.
Nature.
2004;
431
(7007):
402
-
Novel lipid modifications of secreted protein signals.
Mann RK,
Beachy PA.
Annu Rev Biochem.
2004:
73
891-923
-
Roles for Hedgehog signaling in androgen production and prostate ductal morphogenesis.
Berman DM,
Desai N, Wang X, Karhadkar SS, Reynon M, Abate-Shen C, Beachy PA, Shen MM.
Dev Biol.
2004;
267
(2):
387-98
-
The Hedgehog response network: sensors, switches, and routers.
Lum L,
Beachy PA.
Science.
2004;
304
(5678):
1755-9
-
The SmoA1 mouse model reveals that notch signaling is critical for the growth and survival of sonic hedgehog-induced medulloblastomas.
Hallahan AR,
Pritchard JI, Hansen S, Benson M, Stoeck J, Hatton BA, Russell TL, Ellenbogen RG, Bernstein ID, Beachy PA, Olson JM.
Cancer Res.
2004;
64
(21):
7794-800
-
Tissue repair and stem cell renewal in carcinogenesis.
Beachy PA,
Karhadkar SS, Berman DM.
Nature.
2004;
432
(7015):
324-31
-
A defective response to Hedgehog signaling in disorders of cholesterol biosynthesis.
Cooper MK,
Wassif CA, Krakowiak PA, Taipale J, Gong R, Kelley RI, Porter FD, Beachy PA.
Nat Genet.
2003;
33
(4):
508-13
-
Hedgehog signal transduction via Smoothened association with a cytoplasmic complex scaffolded by the atypical kinesin, Costal-2.
Lum L,
Zhang C, Oh S, Mann RK, von Kessler DP, Taipale J, Weis-Garcia F, Gong R, Wang B, Beachy PA.
Mol Cell.
2003;
12
(5):
1261-74
-
Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer.
Watkins DN,
Berman DM, Burkholder SG, Wang B, Beachy PA, Baylin SB.
Nature.
2003;
422
(6929):
313-7
-
Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells.
Lum L,
Yao S, Mozer B, Rovescalli A, Von Kessler D, Nirenberg M, Beachy PA.
Science.
2003;
299
(5615):
2039-45
-
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours.
Berman DM,
Karhadkar SS, Maitra A, Montes De Oca R, Gerstenblith MR, Briggs K, Parker AR, Shimada Y, Eshleman JR, Watkins DN, Beachy PA.
Nature.
2003;
425
(6960):
846-51
-
Differential requirements for shh in mammary tissue and hair follicle morphogenesis.
Gallego MI,
Beachy PA, Hennighausen L, Robinson GW.
Dev Biol.
2002;
249
(1):
131-9
-
Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched.
Ma Y,
Erkner A, Gong R, Yao S, Taipale J, Basler K, Beachy PA.
Cell.
2002;
111
(1):
63-75
-
Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened.
Chen JK,
Taipale J, Cooper MK, Beachy PA.
Genes Dev.
2002;
16
(21):
2743-8
-
Medulloblastoma growth inhibition by hedgehog pathway blockade.
Berman DM,
Karhadkar SS, Hallahan AR, Pritchard JI, Eberhart CG, Watkins DN, Chen JK, Cooper MK, Taipale J, Olson JM, Beachy PA.
Science.
2002;
297
(5586):
1559-61
-
Patched acts catalytically to suppress the activity of Smoothened.
Taipale J,
Cooper MK, Maiti T, Beachy PA.
Nature.
2002;
418
(6900):
892-7
-
Small molecule modulation of Smoothened activity.
Chen JK,
Taipale J, Young KE, Maiti T, Beachy PA.
Proc Natl Acad Sci U S A.
2002;
99
(22):
14071-6
-
Expression and regulation of chicken fibroblast growth factor homologous factor (FHF)-4 during craniofacial morphogenesis.
Muñoz-Sanjuán I,
Cooper MK, Beachy PA, Fallon JF, Nathans J.
Dev Dyn.
2001;
220
(3):
238-45
-
Manifestation of the limb prepattern: limb development in the absence of sonic hedgehog function.
Chiang C,
Litingtung Y, Harris MP, Simandl BK, Li Y, Beachy PA, Fallon JF.
Dev Biol.
2001;
236
(2):
421-35
-
Skinny hedgehog, an acyltransferase required for palmitoylation and activity of the hedgehog signal.
Chamoun Z,
Mann RK, Nellen D, von Kessler DP, Bellotto M, Beachy PA, Basler K.
Science.
2001;
293
(5537):
2080-4
-
The Hedgehog and Wnt signalling pathways in cancer.
Taipale J,
Beachy PA.
Nature.
2001;
411
(6835):
349-54
-
Cholesterol modification of proteins.
Mann RK,
Beachy PA.
Biochim Biophys Acta.
2000;
1529
(1-3):
188-202
-
Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine.
Taipale J,
Chen JK, Cooper MK, Wang B, Mann RK, Milenkovic L, Scott MP, Beachy PA.
Nature.
2000;
406
(6799):
1005-9
-
Genetics of ventral forebrain development and holoprosencephaly.
Muenke M,
Beachy PA.
Curr Opin Genet Dev.
2000;
10
(3):
262-9
-
Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb.
Wang B,
Fallon JF, Beachy PA.
Cell.
2000;
100
(4):
423-34
-
Essential role for Sonic hedgehog during hair follicle morphogenesis.
Chiang C,
Swan RZ, Grachtchouk M, Bolinger M, Litingtung Y, Robertson EK, Cooper MK, Gaffield W, Westphal H, Beachy PA, Dlugosz AA.
Dev Biol.
1999;
205
(1):
1-9
-
Nuclear trafficking of Cubitus interruptus in the transcriptional regulation of Hedgehog target gene expression.
Chen CH,
von Kessler DP, Park W, Wang B, Ma Y, Beachy PA.
Cell.
1999;
98
(3):
305-16
-
Sonic hedgehog protein signals not as a hydrolytic enzyme but as an apparent ligand for patched.
Fuse N,
Maiti T, Wang B, Porter JA, Hall TM, Leahy DJ, Beachy PA.
Proc Natl Acad Sci U S A.
1999;
96
(20):
10992-9
-
Patterning of the embryonic forebrain.
Rubenstein JL,
Beachy PA.
Curr Opin Neurobiol.
1998;
8
(1):
18-26
-
Teratogen-mediated inhibition of target tissue response to Shh signaling.
Cooper MK,
Porter JA, Young KE, Beachy PA.
Science.
1998;
280
(5369):
1603-7
-
Crystal structure of a Hedgehog autoprocessing domain: homology between Hedgehog and self-splicing proteins.
Hall TM,
Porter JA, Young KE, Koonin EV, Beachy PA, Leahy DJ.
Cell.
1997;
91
(1):
85-97
-
Mediation of Sonic hedgehog-induced expression of COUP-TFII by a protein phosphatase.
Krishnan V,
Pereira FA, Qiu Y, Chen CH, Beachy PA, Tsai SY, Tsai MJ.
Science.
1997;
278
(5345):
1947-50
-
Multiple roles of cholesterol in hedgehog protein biogenesis and signaling.
Beachy PA,
Cooper MK, Young KE, von Kessler DP, Park WJ, Hall TM, Leahy DJ, Porter JA.
Cold Spring Harb Symp Quant Biol.
1997:
62
191-204
-
Cholesterol modification of hedgehog signaling proteins in animal development.
Porter JA,
Young KE, Beachy PA.
Science.
1996;
274
(5285):
255-9
-
Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function.
Chiang C,
Litingtung Y, Lee E, Young KE, Corden JL, Westphal H, Beachy PA.
Nature.
1996;
383
(6599):
407-13
-
Hedgehog patterning activity: role of a lipophilic modification mediated by the carboxy-terminal autoprocessing domain.
Porter JA,
Ekker SC, Park WJ, von Kessler DP, Young KE, Chen CH, Ma Y, Woods AS, Cotter RJ, Koonin EV, Beachy PA.
Cell.
1996;
86
(1):
21-34
-
Overexpression of a Rrp1 transgene reduces the somatic mutation and recombination frequency induced by oxidative DNA damage in Drosophila melanogaster.
Szakmary A,
Huang SM, Chang DT, Beachy PA, Sander M.
Proc Natl Acad Sci U S A.
1996;
93
(4):
1607-12
-
pH-dependent enhancement of DNA binding by the ultrabithorax homeodomain.
Li L,
von Kessler D, Beachy PA, Matthews KS.
Biochemistry.
1996;
35
(30):
9832-9
-
A potential catalytic site revealed by the 1.7-A crystal structure of the amino-terminal signalling domain of Sonic hedgehog.
Hall TM,
Porter JA, Beachy PA, Leahy DJ.
Nature.
1995;
378
(6553):
212-6
-
Control of Drosophila tracheal branching by the novel homeodomain gene unplugged, a regulatory target for genes of the bithorax complex.
Chiang C,
Young KE, Beachy PA.
Development.
1995;
121
(11):
3901-12
-
Distinct expression and shared activities of members of the hedgehog gene family of Xenopus laevis.
Ekker SC,
McGrew LL, Lai CJ, Lee JJ, von Kessler DP, Moon RT, Beachy PA.
Development.
1995;
121
(8):
2337-47
-
Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis.
Roelink H,
Porter JA, Chiang C, Tanabe Y, Chang DT, Beachy PA, Jessell TM.
Cell.
1995;
81
(3):
445-55
-
Induction of midbrain dopaminergic neurons by Sonic hedgehog.
Hynes M,
Porter JA, Chiang C, Chang D, Tessier-Lavigne M, Beachy PA, Rosenthal A.
Neuron.
1995;
15
(1):
35-44
-
Limb-patterning activity and restricted posterior localization of the amino-terminal product of Sonic hedgehog cleavage.
López-Martínez A,
Chang DT, Chiang C, Porter JA, Ros MA, Simandl BK, Beachy PA, Fallon JF.
Curr Biol.
1995;
5
(7):
791-6
-
Long-range sclerotome induction by sonic hedgehog: direct role of the amino-terminal cleavage product and modulation by the cyclic AMP signaling pathway.
Fan CM,
Porter JA, Chiang C, Chang DT, Beachy PA, Tessier-Lavigne M.
Cell.
1995;
81
(3):
457-65
-
Patterning activities of vertebrate hedgehog proteins in the developing eye and brain.
Ekker SC,
Ungar AR, Greenstein P, von Kessler DP, Porter JA, Moon RT, Beachy PA.
Curr Biol.
1995;
5
(8):
944-55
-
Patterning of the neural ectoderm of Xenopus laevis by the amino-terminal product of hedgehog autoproteolytic cleavage.
Lai CJ,
Ekker SC, Beachy PA, Moon RT.
Development.
1995;
121
(8):
2349-60
-
The product of hedgehog autoproteolytic cleavage active in local and long-range signalling.
Porter JA,
von Kessler DP, Ekker SC, Young KE, Lee JJ, Moses K, Beachy PA.
Nature.
1995;
374
(6520):
363-6
-
Ultrabithorax protein is necessary but not sufficient for full activation of decapentaplegic expression in the visceral mesoderm.
Sun B,
Hursh DA, Jackson D, Beachy PA.
EMBO J.
1995;
14
(3):
520-35
-
Autoproteolysis in hedgehog protein biogenesis.
Lee JJ,
Ekker SC, von Kessler DP, Porter JA, Sun BI, Beachy PA.
Science.
1994;
266
(5190):
1528-37
-
Expression of a novel Toll-like gene spans the parasegment boundary and contributes to hedgehog function in the adult eye of Drosophila.
Chiang C,
Beachy PA.
Mech Dev.
1994;
47
(3):
225-39
-
Products, genetic linkage and limb patterning activity of a murine hedgehog gene.
Chang DT,
López A, von Kessler DP, Chiang C, Simandl BK, Zhao R, Seldin MF, Fallon JF, Beachy PA.
Development.
1994;
120
(11):
3339-53
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The degree of variation in DNA sequence recognition among four Drosophila homeotic proteins.
Ekker SC,
Jackson DG, von Kessler DP, Sun BI, Young KE, Beachy PA.
EMBO J.
1994;
13
(15):
3551-60
-
The novel homeodomain gene buttonless specifies differentiation and axonal guidance functions of Drosophila dorsal median cells.
Chiang C,
Patel NH, Young KE, Beachy PA.
Development.
1994;
120
(12):
3581-93
-
Cooperative binding of an Ultrabithorax homeodomain protein to nearby and distant DNA sites.
Beachy PA,
Varkey J, Young KE, von Kessler DP, Sun BI, Ekker SC.
Mol Cell Biol.
1993;
13
(11):
6941-56
-
The segment polarity gene hedgehog is required for progression of the morphogenetic furrow in the developing Drosophila eye.
Ma C,
Zhou Y, Beachy PA, Moses K.
Cell.
1993;
75
(5):
927-38
-
Differential DNA sequence recognition is a determinant of specificity in homeotic gene action.
Ekker SC,
von Kessler DP, Beachy PA.
EMBO J.
1992;
11
(11):
4059-72
-
Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog.
Lee JJ,
von Kessler DP, Parks S, Beachy PA.
Cell.
1992;
71
(1):
33-50
-
Optimal DNA sequence recognition by the Ultrabithorax homeodomain of Drosophila.
Ekker SC,
Young KE, von Kessler DP, Beachy PA.
EMBO J.
1991;
10
(5):
1179-86
-
A molecular view of the Ultrabithorax homeotic gene of Drosophila.
Beachy PA,
Trends Genet.
1990;
6
(2):
46-51
-
Structure and expression of a family of Ultrabithorax mRNAs generated by alternative splicing and polyadenylation in Drosophila.
Kornfeld K,
Saint RB, Beachy PA, Harte PJ, Peattie DA, Hogness DS.
Genes Dev.
1989;
3
(2):
243-58
-
An Ultrabithorax protein binds sequences near its own and the Antennapedia P1 promoters.
Beachy PA,
Krasnow MA, Gavis ER, Hogness DS.
Cell.
1988;
55
(6):
1069-81
-
Segmental distribution of bithorax complex proteins during Drosophila development.
Beachy PA,
Helfand SL, Hogness DS.
Nature.
1985 Feb 14-20;
313
(6003):
545-51
-
Regulation and products of the Ubx domain of the bithorax complex.
Hogness DS,
Lipshitz HD, Beachy PA, Peattie DA, Saint RB, Goldschmidt-Clermont M, Harte PJ, Gavis ER, Helfand SL.
Cold Spring Harb Symp Quant Biol.
1985:
50
181-94
-
Molecular Genetics of the Bithorax Complex in Drosophila melanogaster.
Bender W,
Akam M, Karch F, Beachy PA, Peifer M, Spierer P, Lewis EB, Hogness DS.
Science.
1983;
221
(4605):
23-9
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