{"result":[{"lastName":"Genovese","clinicalFocus":[{"focus":"Rheumatology"},{"focus":"Immunology/Rheumatology"}],"appointments":[{"appointment":"Professor - Med Center Line,Medicine - Immunology & Rheumatology"}],"primaryAppointment":"Professor - Med Center Line,Medicine - Immunology & Rheumatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4195&type=small&showNoImage","displayName":"Mark Genovese","firstName":"Mark","href":"http://med.stanford.edu/profiles/Mark_Genovese","researchInterest":"Clinical trials and interventions in the rheumatic diseases including Rheumatoid Arthritis,Systemic Lupus Erythematosus, Systemic Sclerosis, Osteoarthritis."},{"lastName":"Fries","clinicalFocus":[{"focus":"Immunology and Rheumatology"},{"focus":"Rheumatology"}],"appointments":[{"appointment":"Professor Emeritus,Medicine - Immunology & Rheumatology"},{"appointment":"Emeritus Faculty, Acad Council,Medicine - Immunology & Rheumatology"}],"primaryAppointment":"Professor Emeritus,Medicine - Immunology & Rheumatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4601&type=small&showNoImage","displayName":"James F. Fries","firstName":"James","href":"http://med.stanford.edu/profiles/James_Fries","researchInterest":"National chronic disease data bank systems; clinical, epidemiology of arthritis; antecedents of human aging; assessment of, technology"},{"lastName":"Utz","clinicalFocus":[{"focus":"Immunology and Rheumatology"},{"focus":"Rheumatology"}],"appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4001&type=small&showNoImage","displayName":"Paul Utz","firstName":"Paul","href":"http://med.stanford.edu/profiles/Paul_Utz","researchInterest":"The long-term research goal of Dr. Utz\u0092s laboratory is (1) to develop a better understanding of the pathogenic mechanisms underlying systemic lupus erythematosus (SLE) and other autoimmune diseases by exploring signaling pathways that are activated during apoptosis; and (2) to better understand the complicated process of programmed cell death."},{"lastName":"Lyon","clinicalFocus":[{"focus":"Rheumatology"}],"appointments":[],"imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=12691&type=small&showNoImage","displayName":"Michael Lyon","firstName":"Michael","href":"http://med.stanford.edu/profiles/Michael_Lyon","researchInterest":""},{"lastName":"Graef","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Pathology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7247&type=small&showNoImage","displayName":"Isabella Graef","firstName":"Isabella","href":"http://med.stanford.edu/profiles/Isabella_Graef","researchInterest":"We are interested in addressing questions in neuronal development and function by a combination of genetic, cell biological, biochemical and chemical approaches. \r\nThe main focus of our lab is centered around two topics: 1) the interface of signaling and gene regulation in neuronal development, with a focus on calcineurin-NFAT signaling; 2) the development of small molecules, which interfere with protein-protein interactions underlying neurodegenerative diseases."},{"lastName":"Cyert","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6213&type=small&showNoImage","displayName":"Martha Cyert","firstName":"Martha","href":"http://med.stanford.edu/profiles/Martha_Cyert","researchInterest":"Cells respond to extracellular changes by activating signal transduction pathways, many of which are highly conserved. We study Ca2+-mediated signaling in a simple eukaryote, Saccharomyces cerevisiae. Using genetic, genomic, biochemical and cell biological approaches, we are examining how the Ca2+/calmodulin-regulated phosphatase, calcineurin, regulates gene expression and other cellular processes in response to environmental stress."},{"lastName":"Snyder","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=13465&type=small&showNoImage","displayName":"Michael Snyder","firstName":"Michael","href":"http://med.stanford.edu/profiles/Michael_Snyder","researchInterest":"We are presently in an omics revolution in which genomes and other omes can be readily characterized. Our laboratory uses a variety of approaches to analyze genomes and regulatory networks. Our research focuses on yeast, an ideal model organism ideally suited to genetic analysis, and humans.\r\n\r\n1) Transcriptomes\r\nTo annotate genomes, we developed RNA sequencing for annotation the yeast and human transcriptomes. We discovered that the eukaryotic transcriptome is much more complex than previously"},{"lastName":"Busque","clinicalFocus":[{"focus":"General Surgery"},{"focus":"Kidney and Pancreas Transplantation"},{"focus":"Liver Transplantation"}],"appointments":[{"appointment":"Professor - Med Center Line,Surgery - Multi-Organ Transplantation"}],"primaryAppointment":"Professor - Med Center Line,Surgery - Multi-Organ Transplantation","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3809&type=small&showNoImage","displayName":"Stephan Busque","firstName":"Stephan","href":"http://med.stanford.edu/profiles/Stephan_Busque","researchInterest":"My research interest is focused on the improvement of clinical immunosuppression. I am  involved  in the evaluation of new immunosuppressive drugs, potentially more efficacious or less toxic.  My ultimate goal is to achieve tolerance, a state that would obviate the need for any drugs. I am an investigator part of a multidisciplinary tolerance induction project using total lymphoid irradiation and donor hematopoietic stem cells infusion after living donor kidney transplantation."},{"lastName":"Simard","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Health Research & Policy - Epidemiology"},{"appointment":"Assistant Professor (By courtesy),Medicine - Immunology & Rheumatology"}],"primaryAppointment":"Assistant Professor,Health Research & Policy - Epidemiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=35300&type=small&showNoImage","displayName":"Julia Simard","firstName":"Julia","href":"http://med.stanford.edu/profiles/Julia_Simard","researchInterest":""},{"lastName":"Pringle","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7022&type=small&showNoImage","displayName":"John R. Pringle","firstName":"John","href":"http://med.stanford.edu/profiles/John_Pringle","researchInterest":"Much of our research exploits the power of yeast as an experimentally tractable model eukaryote to investigate fundamental problems in cell and developmental biology such as the mechanisms of cell polarization and cytokinesis.  In another project, we are developing the small sea anemone Aiptasia as a model system for study of the molecular and cellular biology of dinoflagellate-cnidarian symbiosis, which is critical for the survival of most corals but still very poorly understood."},{"lastName":"Martinez","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Surgery - Multi-Organ Transplantation"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Professor (Research),Surgery - Multi-Organ Transplantation","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4474&type=small&showNoImage","displayName":"Olivia Martinez","firstName":"Olivia","href":"http://med.stanford.edu/profiles/Olivia_Martinez","researchInterest":"EBV B cell lymphomas; pathways of immune evasion in the growth and survival of EBV B cell lymphomas;  mechanisms of graft rejection and tolerance induction; stem cell and solid organ transplantation."},{"lastName":"Goronzy","clinicalFocus":[{"focus":"Vasculitis"},{"focus":"Rheumatoid Arthritis"},{"focus":"Immunology"}],"appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=15394&type=small&showNoImage","displayName":"Jorg Goronzy","firstName":"Jorg","href":"http://med.stanford.edu/profiles/Jorg_Goronzy","researchInterest":""},{"lastName":"Weyand","clinicalFocus":[{"focus":"Immunology"},{"focus":"Vasculitis"},{"focus":"Rheumatoid Arthritis"}],"appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=15618&type=small&showNoImage","displayName":"Cornelia Weyand","firstName":"Cornelia","href":"http://med.stanford.edu/profiles/Cornelia_Weyand","researchInterest":""},{"lastName":"Ko","clinicalFocus":[{"focus":"Dermatology"},{"focus":"Skin Cancer"},{"focus":"Screening for melanoma in high risk patients (family history, red hair, many moles)"},{"focus":"Psoriasis"},{"focus":"Laser Therapy of Medical Skin Conditions"},{"focus":"Telehealth"}],"appointments":[{"appointment":"Clinical Assistant Professor,Dermatology"}],"primaryAppointment":"Clinical Assistant Professor,Dermatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=36790&type=small&showNoImage","displayName":"Justin Ko","firstName":"Justin","href":"http://med.stanford.edu/profiles/Justin_Ko","researchInterest":""},{"lastName":"Bloch","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Health Research & Policy - Biostatistics"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Health Research & Policy - Biostatistics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4604&type=small&showNoImage","displayName":"Daniel Bloch","firstName":"Daniel","href":"http://med.stanford.edu/profiles/Daniel_Bloch","researchInterest":""},{"lastName":"Chung","clinicalFocus":[{"focus":"Immunology and Rheumatology"},{"focus":"Rheumatology"},{"focus":"Scleroderma, Systemic"},{"focus":"Connective Tissue Diseases"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Medicine - Immunology & Rheumatology"},{"appointment":"Assistant Professor - Med Center Line (By courtesy),Dermatology"}],"primaryAppointment":"Assistant Professor - Med Center Line,Medicine - Immunology & Rheumatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7580&type=small&showNoImage","displayName":"Lorinda Chung","firstName":"Lorinda","href":"http://med.stanford.edu/profiles/Lorinda_Chung","researchInterest":""},{"lastName":"Hu","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Obstetrics & Gynecology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Obstetrics & Gynecology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10405&type=small&showNoImage","displayName":"Mickey Hu","firstName":"Mickey","href":"http://med.stanford.edu/profiles/Mickey_Hu","researchInterest":""},{"lastName":"Strober","clinicalFocus":[{"focus":"Immunology and Rheumatology"},{"focus":"Rheumatology"}],"appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4152&type=small&showNoImage","displayName":"Samuel Strober","firstName":"Samuel","href":"http://med.stanford.edu/profiles/Samuel_Strober","researchInterest":"Mechanisms of immune tolerance; regulatory processes in autoimmunity and transplantation and extrathymic T cell maturation."},{"lastName":"Bonham","clinicalFocus":[{"focus":"General Surgery"},{"focus":"Liver Transplantation"},{"focus":"Live-donor Liver Transplantation"},{"focus":"Pediatric Transplantation"},{"focus":"Intestinal Transplantation"},{"focus":"Kidney and Pancreas Transplantation"},{"focus":"Portal Hypertension"},{"focus":"Hepatobiliary Surgery"},{"focus":"Cancer of Biliary Tract"},{"focus":"Cancer, Liver"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Surgery - Multi-Organ Transplantation"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor - Med Center Line,Surgery - Multi-Organ Transplantation","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3884&type=small&showNoImage","displayName":"Clark Bonham","firstName":"Clark","href":"http://med.stanford.edu/profiles/Clark_Bonham","researchInterest":"Tolerance induction in liver transplantation.\r\nHepatocyte transplantation."},{"lastName":"Gorsulowsky","clinicalFocus":[{"focus":"Dermatology"}],"appointments":[],"imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7884&type=small&showNoImage","displayName":"David C Gorsulowsky MD","firstName":"David","href":"http://med.stanford.edu/profiles/David_Gorsulowsky","researchInterest":""},{"lastName":"Grimm","clinicalFocus":[{"focus":"Pediatric Nephrology"}],"appointments":[{"appointment":"Professor - Med Center Line,Pediatrics - Nephrology"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Professor - Med Center Line,Pediatrics - Nephrology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7989&type=small&showNoImage","displayName":"Paul C. Grimm","firstName":"Paul","href":"http://med.stanford.edu/profiles/Paul_Grimm","researchInterest":"Computerized image analysis of kidney and liver biopsies to quantitate and diagnose subtle changes in tissue structure. \r\nRenal Inflammation\r\nRenal Allograft Rejection\r\nRenal Fibrosis in; \r\n-Primary Kidney Disease\r\n-Transplant Kidney Disease\r\nLiver fibrosis\r\nSteatohepatitis"},{"lastName":"Chu","clinicalFocus":[{"focus":"Rheumatology"}],"appointments":[],"imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9030&type=small&showNoImage","displayName":"Alvina Chu","firstName":"Alvina","href":"http://med.stanford.edu/profiles/Alvina_Chu","researchInterest":""},{"lastName":"Berg","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Biochemistry"},{"appointment":"Professor Emeritus,SoM Dean's Office Administrative Units - Dean's Office Operations"},{"appointment":"Professor Emeritus,Biochemistry"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6263&type=small&showNoImage","displayName":"Paul Berg","firstName":"Paul","href":"http://med.stanford.edu/profiles/Paul_Berg","researchInterest":"For about 10 years until 2000, my lab's research activities were focused on the mechanism of recombinational repair of double-strand breaks in DNA. We focused our efforts on two model systems:  one involved the repair of restriction enzyme cleavages at specific mammalian chromosomal loci and the second explored the biochemical properties of purified yeast Rad51 protein, an essential catalyst for synapsing the broken ends of DNA with an intact homologue of that sequence.  We also explored the ro"}]}