{"result":[{"lastName":"Bass","clinicalFocus":[{"focus":"Gastroenterology/Nutrition/Hepatology, Pediatric"},{"focus":"Pediatric Gastroenterology"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Pediatrics - Gastroenterology"}],"primaryAppointment":"Associate Professor - Med Center Line,Pediatrics - Gastroenterology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4017&type=small&showNoImage","displayName":"Dorsey Bass","firstName":"Dorsey","href":"http://med.stanford.edu/profiles/dean/researcher/Dorsey_Bass","researchInterest":"Our laboratory is interested in the pathophysiology, immunology, and epidemiology of viral gastroenteritis."},{"lastName":"Butcher","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4498&type=small&showNoImage","displayName":"Eugene Butcher","firstName":"Eugene","href":"http://med.stanford.edu/profiles/dean/researcher/Eugene_Butcher","researchInterest":"Our interests include: \r\n1) The physiology and significance of lymphocyte homing in local and systemic immunity; \r\n2) biochemical and genetic studies of molecules that direct leukocyte recruitment; \r\n3) cellular and molecular genetic studies of leukocyte chemotaxis and the role of chemokines; \r\n4) vascular differentiation in normal and pathologic inflammatory states; \r\n5) systems and chemical biology approaches to understanding the regulation of lymphocyte trafficking programs."},{"lastName":"Herzenberg","clinicalFocus":[],"appointments":[{"appointment":"Emeritus (Active) Professor,Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Emeritus (Active) Professor,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4151&type=small&showNoImage","displayName":"Leonard Herzenberg","firstName":"Leonard","href":"http://med.stanford.edu/profiles/dean/researcher/Leonard_Herzenberg","researchInterest":"Gene Regulation; Molecular Immunology; Lymphocyte subsets; Fluorescence-Activated Cell\u000bSorter (FACS) development; AIDS; Apoptosis; Redox Regulation; Gene Arrays; and the theraphy of AIDS using the anti-oxidant N'acetylcysteine(NAC)."},{"lastName":"Lewis","clinicalFocus":[{"focus":"Infectious Diseases, Pediatric"},{"focus":"Pediatric Infectious Disease"}],"appointments":[{"appointment":"Professor - Med Center Line,Pediatrics - Immunology & Transplant Biology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor - Med Center Line,Pediatrics - Immunology & Transplant Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4439&type=small&showNoImage","displayName":"David B. Lewis","firstName":"David","href":"http://med.stanford.edu/profiles/dean/researcher/David_Lewis","researchInterest":"My laboratory has two major research interests.  First, to define cellular and molecular mechanisms that limit T cell responses to vaccines and pathogens during normal early postnatal development and in cases of inherited genetic immunodeficiencies.  Second, to determine how these limitations in immunity can be overcome by using novel approaches for vaccine adjuvants, with a particular focus on anti-viral vaccines."},{"lastName":"Herzenberg","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Genetics"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor (Research),Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6113&type=small&showNoImage","displayName":"Leonore A. Herzenberg","firstName":"Leonore","href":"http://med.stanford.edu/profiles/dean/researcher/Leonore_Herzenberg","researchInterest":"B-cell development; Ig rearrangement and repertoire analysis; T cell regulation of antibody\u000bresponses; T cell subsets; glutathione regulation of HIV disease progression; Fluorescence-Activated Cell Sorting (FACS) related software development and gene arrays."},{"lastName":"Cheung","clinicalFocus":[{"focus":"Gastroenterology"},{"focus":"Hepatology (Liver)"}],"appointments":[{"appointment":"Professor - Med Center Line,Medicine - Gastroenterology & Hepatology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor - Med Center Line,Medicine - Gastroenterology & Hepatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4732&type=small&showNoImage","displayName":"Ramsey Cheung","firstName":"Ramsey","href":"http://med.stanford.edu/profiles/dean/researcher/Ramsey_Cheung","researchInterest":"Dr. Cheung's research interests focus on liver diseases, with emphasis on viral hepatitis. His past research include investigating the mechanism of viral neutralization of hepatitis B virus at the molecular level and immune response to hepatitis C virus. Dr. Cheung is studing various aspects of hepatitis C, both clinical and translational research."},{"lastName":"Nolan","clinicalFocus":[],"appointments":[{"appointment":"Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Microbiology & Immunology - Baxter Laboratory","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4713&type=small&showNoImage","displayName":"Garry Nolan","firstName":"Garry","href":"http://med.stanford.edu/profiles/dean/researcher/Garry_Nolan","researchInterest":"Dr. Nolan's group uses high throughput single cell analysis technology of kinase driven signaling cascades to interrogate autoimmunity, cancer, virology (influenza), bacterial pathogens (Listeria and Salmonella) as well as understanding normal immune system function.  Using advanced flow cytometric techniques and computational biology approaches, we focus on high throughput drug screening, mouse models of disease in patient materials, and understanding disease processes at the single cell level."},{"lastName":"Glenn","clinicalFocus":[{"focus":"Gastroenterology"}],"appointments":[{"appointment":"Associate Professor,Medicine - Gastroenterology & Hepatology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Medicine - Gastroenterology & Hepatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4576&type=small&showNoImage","displayName":"Jeffrey S.  Glenn, M.D., Ph.D.","firstName":"Jeffrey","href":"http://med.stanford.edu/profiles/dean/researcher/Jeffrey_Glenn","researchInterest":"Dr. Glenn's primary interest is in molecular virology, with a strong emphasis on translating this knowledge into novel antiviral therapies. Other interests include exploitation of hepatic stem cells, engineered human liver tissues, and new biodefense antiviral strategies."},{"lastName":"Varghese","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, School of Medicine"}],"primaryAppointment":"Postdoctoral Research fellow, School of Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10207&type=small&showNoImage","displayName":"Vici Varghese","firstName":"Vici","href":"http://med.stanford.edu/profiles/dean/researcher/Vici_Varghese","researchInterest":""},{"lastName":"Foung","clinicalFocus":[{"focus":"Pathology"},{"focus":"Pathology and Laboratory Medicine"}],"appointments":[{"appointment":"Professor,Pathology"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4155&type=small&showNoImage","displayName":"Steven Foung","firstName":"Steven","href":"http://med.stanford.edu/profiles/dean/researcher/Steven_Foung","researchInterest":"Our research focus is on the early events of hepatitis C virus infection- virus attachment and entry into susceptible cells. The approach is through the generation and functional studies of human monoclonal antibodies (HMAbs) to the virus envelope proteins with an emphasis on antibodies to conformational epitopes."},{"lastName":"Dekker","clinicalFocus":[{"focus":"Pediatric Infectious Disease"},{"focus":"Vaccine Clinical Trials"},{"focus":"Vaccine Safety"},{"focus":"Infectious Diseases, Pediatric"}],"appointments":[{"appointment":"Professor (Research),Pediatrics - Infectious Diseases"}],"primaryAppointment":"Professor (Research),Pediatrics - Infectious Diseases","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3858&type=small&showNoImage","displayName":"Cornelia L. Dekker, M.D.","firstName":"Cornelia","href":"http://med.stanford.edu/profiles/dean/researcher/Cornelia_Dekker","researchInterest":"The Stanford-LPCH Program provides an infrastructure for conducting clinical studies of new vaccines in children and adults. Current emphasis is on seasonal and avian influenza, malaria and smallpox vaccine studies. We secreend 20,000 newborn infants for congenital HCMV infection in 3 local hospitals and continue with prospective audiology and immunology follow-up of identified children. Additionally, we are a CDC Clinical Immunization Safety Assessment site to evaluate licensed vaccine safety."},{"lastName":"Engleman","clinicalFocus":[{"focus":"Pathology"},{"focus":"Pathology and Laboratory Medicine"}],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Professor,Medicine"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4490&type=small&showNoImage","displayName":"Edgar Engleman","firstName":"Edgar","href":"http://med.stanford.edu/profiles/dean/researcher/Edgar_Engleman","researchInterest":"Dendritic cells, NK cells and T cells; functional proteins and genes; immunotherapeutic approaches to cancer and autoimmune disease."},{"lastName":"Davis","clinicalFocus":[],"appointments":[{"appointment":"Professor,Microbiology & Immunology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4282&type=small&showNoImage","displayName":"Mark M. Davis","firstName":"Mark","href":"http://med.stanford.edu/profiles/dean/researcher/Mark_Davis","researchInterest":"Molecular mechanisms of lymphocyte recognition and differentiation; molecular genetics and expression of T-cell receptor genes.  Dynamics and functionality of specific T cell populations in human cancer."},{"lastName":"Oliver","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pediatrics"}],"primaryAppointment":"Postdoctoral Research fellow, Pediatrics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9813&type=small&showNoImage","displayName":"Stefan Oliver","firstName":"Stefan","href":"http://med.stanford.edu/profiles/dean/researcher/Stefan_Oliver","researchInterest":""},{"lastName":"Levy","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor (Research),Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4307&type=small&showNoImage","displayName":"Shoshana Levy","firstName":"Shoshana","href":"http://med.stanford.edu/profiles/dean/researcher/Shoshana_Levy","researchInterest":"Our research focuses on the mechanism of action of tetraspanins, an evolutionary conserved, widely expressed multi-gene family. We study a prototype, CD81, a molecule implicated in the pathogenesis of two major human diseases: hepatitis C virus (HCV) and malaria."},{"lastName":"Chien","clinicalFocus":[],"appointments":[{"appointment":"Professor,Microbiology & Immunology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4121&type=small&showNoImage","displayName":"Yueh-hsiu Chien","firstName":"Yueh-Hsiu","href":"http://med.stanford.edu/profiles/dean/researcher/Yueh-Hsiu_Chien","researchInterest":"Contribution of T cells to immunocompetence and autoimmunity; how the immune system clears infection, avoids autoimmunity and how infection impacts on the development of immune responses."},{"lastName":"Garcia","clinicalFocus":[],"appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Professor,Structural Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4370&type=small&showNoImage","displayName":"Chris Garcia","firstName":"Chris","href":"http://med.stanford.edu/profiles/dean/researcher/Chris_Garcia","researchInterest":"Structural and functional studies of transmembrane receptor interactions with their ligands in systems relevant to human health and disease - primarily in immunity, infection, and neurobiology.  We study these problems using protein engineering, structural, biochemical, and combinatorial biology approaches."},{"lastName":"Fathman","clinicalFocus":[{"focus":"Immunology"},{"focus":"Immunology and Rheumatology"}],"appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4479&type=small&showNoImage","displayName":"C. Garrison Fathman","firstName":"C","href":"http://med.stanford.edu/profiles/dean/researcher/C_Fathman","researchInterest":"My lab of molecular and cellular immunology is interested in research in the general field of T cell activation and autoimmunity.   We use lentiviral mediated transduction of murine dendritic cells with immunoregulatory proteins for site specific and targeted immunotherapy. We have idintified a gene (GRAIL) that seems to control T cell anergy and are defining the regulatory T cell core transcriptome.  Additional studies are on the mechanism of effect of anti-CD3 antibodies in therapy of T1D."},{"lastName":"Michie","clinicalFocus":[{"focus":"Anatomic Pathology"},{"focus":"Pathology and Laboratory Medicine"}],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4707&type=small&showNoImage","displayName":"Sara Michie","firstName":"Sara","href":"http://med.stanford.edu/profiles/dean/researcher/Sara_Michie","researchInterest":"Lymphocyte/endothelial cell adhesion mechanisms involved in lymphocyte migration to sites of inflammation; regulation of expression of endothelial cell adhesion molecules."},{"lastName":"Mocarski","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Microbiology & Immunology"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4146&type=small&showNoImage","displayName":"Edward Mocarski","firstName":"Edward","href":"http://med.stanford.edu/profiles/dean/researcher/Edward_Mocarski","researchInterest":"Research focusses on one of the human herpesviruses: cytomegalovirus (CMV). This virus is a major medical problem in immunocompromised individuals. The virus is very large, carrying over 200 genes. We have characterized functions involved in viral growth (regulation of gene expression, replication, genome packaging) and pathogenesis (tissue tropism, latency). Molecular genetic and biochemical approaches have been employed to dissect these functions."},{"lastName":"Strober","clinicalFocus":[{"focus":"Immunology and Rheumatology"},{"focus":"Rheumatology"}],"appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4152&type=small&showNoImage","displayName":"Samuel Strober","firstName":"Samuel","href":"http://med.stanford.edu/profiles/dean/researcher/Samuel_Strober","researchInterest":"Mechanisms of immune tolerance; regulatory processes in autoimmunity and transplantation and extrathymic T cell maturation."},{"lastName":"Arvin","clinicalFocus":[{"focus":"Infectious Diseases, Pediatric"},{"focus":"Pediatric Infectious Disease"}],"appointments":[{"appointment":"Professor,Pediatrics - Infectious Diseases"},{"appointment":"Professor,Microbiology & Immunology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Pediatrics - Infectious Diseases","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4188&type=small&showNoImage","displayName":"Ann M. Arvin","firstName":"Ann","href":"http://med.stanford.edu/profiles/dean/researcher/Ann_Arvin","researchInterest":"Our laboratory investigates the pathogenesis of varicella zoster virus (VZV) infection, focusing on the functional roles of particular viral gene products in pathogenesis and virus-cell interactions in differentiated human cells  in humans and in Scid-hu mouse models of VZV cell tropisms in vivo, and the immunobiology of VZV infections."},{"lastName":"Habtezion","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Medicine - Gastroenterology & Hepatology"}],"primaryAppointment":"Instructor,Medicine - Gastroenterology & Hepatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7230&type=small&showNoImage","displayName":"Aida Habtezion","firstName":"Aida","href":"http://med.stanford.edu/profiles/dean/researcher/Aida_Habtezion","researchInterest":""},{"lastName":"Keeffe","clinicalFocus":[{"focus":"Hepatology (Liver)"},{"focus":"Chronic Hepatitis B"},{"focus":"Chronic Hepatitis C"},{"focus":"Liver Transplantation"},{"focus":"Gastroenterology"}],"appointments":[{"appointment":"Emeritus Faculty-Med Ctr Line,Medicine - Gastroenterology & Hepatology"}],"primaryAppointment":"Emeritus Faculty-Med Ctr Line,Medicine - Gastroenterology & Hepatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4208&type=small&showNoImage","displayName":"Emmet B. Keeffe, MD","firstName":"Emmet","href":"http://med.stanford.edu/profiles/dean/researcher/Emmet_Keeffe","researchInterest":"My clinical research interest is currently focused primarily on antiviral treatment of chronic hepatitis C with nitazoxanide and antiviral therapy of chronic hepatitis B, as well as application of hepatitis vaccines and selection and outcomes of liver transplantation in the recent past."},{"lastName":"Parnes","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Medicine - Immunology & Rheumatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4487&type=small&showNoImage","displayName":"Jane Parnes","firstName":"Jane","href":"http://med.stanford.edu/profiles/dean/researcher/Jane_Parnes","researchInterest":"The lab is studying the mechanisms controlling B cell responsiveness and the balance between tolerance and autoimmunity.  B cells deficient in CD72 are hyperresponsive to stimulation through the B cell receptor.  We are examining the alterations in B cell signaling in these B cells and the mechanisms by which CD72 deficiency partially abrogates anergic tolerance.  We hope to learn how deficiency in CD72 leads to spontaneous autoimmunity and increased susceptibility to induced autoimmune disease."}]}