Philip A. Pizzo, M.D.
Publication Details
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Effect of zidovudine and didanosine treatment on heart function in children infected with human immunodeficiency virus.
J Pediatr. 1995; (1): 137-46
Human immunodeficiency virus (HIV) infection in children can be complicated by the development of cardiac disease. Decreased left ventricular function has been temporally associated with the use of zidovudine (azidothymidine; AZT) in adults with HIV and has been associated with changes in cardiac muscle mitochondria in animal models. This study was done in an attempt to determine whether the cardiac disease is related to the antiretroviral therapy or to progressive HIV infection.
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