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Sara MichieAcademic Appointments
Appointment
Organization
Professor
Member
Immunology ;
Pathology ;
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Research Interests
Our laboratory studies the molecular mechanisms that control the migration of lymphocytes into sites of autoimmune-mediated tissue damage, such as pancreatic islets in type 1 diabetes and salivary glands in Sjogren’s syndrome. Our long-term goals include better understanding of the pathogenesis of autoimmune diseases, and development of novel diagnostic and therapeutic strategies.
Publications
- Shen WJ, Liang Y, Wang J, Harada K, Patel S, Michie SA, Osuga JI, Ishibashi S, Kraemer FB "Regulation of hormone-sensitive lipase in islets." Diabetes Res Clin Pract 2006; More »
- Lee LF, Xu B, Michie SA, Beilhack GF, Warganich T, Turley S, McDevitt HO "The role of TNF-{alpha} in the pathogenesis of type 1 diabetes in the nonobese diabetic mouse: Analysis of dendritic cell maturation." Proc Natl Acad Sci U S A 2005; More »
- Nakamichi I, Toivola DM, Strnad P, Michie SA, Oshima RG, Baribault H, Omary MB "Keratin 8 overexpression promotes mouse Mallory body formation." J Cell Biol 2005; 171: 6: 931-7 More »
- Yu S, Michie SA, Lowe AW "Absence of the major zymogen granule membrane protein, GP2, does not affect pancreatic morphology or secretion." J Biol Chem 2004; More »
- Tao GZ, Toivola DM, Zhong B, Michie SA, Resurreccion EZ, Tamai Y, Taketo MM, Omary MB "Keratin-8 null mice have different gallbladder and liver susceptibility to lithogenic diet-induced injury." J Cell Sci 2003; 116: Pt 22: 4629-38 More »
37 publications: view full list
