Cardiovascular Medicine IN THE DEPARTMENT OF MEDICINE

Philip S. Tsao, PhD

Publication Details

  • Distribution of asymmetric dimethylarginine among 980 healthy, older adults of different ethnicities.

    Sydow K, Fortmann SP, Fair JM, Varady A, Hlatky MA, Go AS, Iribarren C, Tsao PS. Clin Chem. 2010; 56 (1): 111-20

    Endothelium-derived nitric oxide plays a crucial role in the regulation of vascular tone and the development of cardiovascular disease. The endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine (ADMA) has emerged as a novel cardiovascular risk factor. ADMA appears to be an independent predictor for cardiovascular and overall mortality. However, the majority of studies investigating the clinical role of ADMA were performed in European study populations with few individuals of other ethnicities.

    PubMedID: 19892843

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