Philip S. Tsao, PhD
Publication Details
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Stent-based delivery of sirolimus reduces neointimal formation in a porcine coronary model.
Circulation. 2001; (10): 1188-93
The purpose of this study was to determine the efficacy of stent-based delivery of sirolimus (SRL) alone or in combination with dexamethasone (DEX) to reduce in-stent neointimal hyperplasia. SRL is a potent immunosuppressive agent that inhibits SMC proliferation by blocking cell cycle progression.
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