William Clusin, MD

Publications

• Role of sodium/calcium exchange in heart failure-induced arrhythmias: a potential therapeutic target. Clusin WT, Heart Rhythm. 2012; 9 (4): 579-80
• Low-dose growth hormone is cardioprotective in uremia. Rabkin R, Awwad I, Chen Y, Ashley EA, Sun D, Sood S, Clusin W, Heidenreich P, Piecha G, Gross ML. J Am Soc Nephrol. 2008; 19 (9): 1774-83
• Mechanisms of calcium transient and action potential alternans in cardiac cells and tissues. Clusin WT, Am J Physiol Heart Circ Physiol. 2008; 294 (1): H1-H10
• Calcium and cardiac arrhythmias: DADs, EADs, and alternans. Clusin WT, Crit Rev Clin Lab Sci. 2003; 40 (3): 337-75
• Spatial heterogeneity of action potential alternans during global ischemia in the rabbit heart. Qian YW, Sung RJ, Lin SF, Province R, Clusin WT. Am J Physiol Heart Circ Physiol. 2003; 285 (6): H2722-33
• Spatial heterogeneity of calcium transient alternans during the early phase of myocardial ischemia in the blood-perfused rabbit heart. Qian YW, Clusin WT, Lin SF, Han J, Sung RJ. Circulation. 2001; 104 (17): 2082-7
• Calcium channel blockers: current controversies and basic mechanisms of action. Clusin WT, Anderson ME. Adv Pharmacol. 1999: 46 253-96
• Calcium transient alternans in blood-perfused ischemic hearts: observations with fluorescent indicator fura red. Wu Y, Clusin WT. Am J Physiol. 1997; 273 (5 Pt 2): H2161-9
• Endothelin activates voltage-dependent Ca2+ current by a G protein-dependent mechanism in rabbit cardiac myocytes. Lauer MR, Gunn MD, Clusin WT. J Physiol. 1992: 448 729-47
• In vivo electrophysiological detection of myocardial ischemia through monophasic action potential recording. Mohabir R, Franz MR, Clusin WT. Prog Cardiovasc Dis. 1991 Jul-Aug; 34 (1): 15-28
• Effects of ischemia and hypercarbic acidosis on myocyte calcium transients, contraction, and pHi in perfused rabbit hearts. Mohabir R, Lee HC, Kurz RW, Clusin WT. Circ Res. 1991; 69 (6): 1525-37
• Effect of platelet release products on cytosolic calcium in cardiac myocytes. Chien WW, Mohabir R, Newman D, Leung LL, Clusin WT. Biochem Biophys Res Commun. 1990; 170 (3): 1121-7
• Effect of thrombin on calcium homeostasis in chick embryonic heart cells. Receptor-operated calcium entry with inositol trisphosphate and a pertussis toxin-sensitive G protein as second messengers. Chien WW, Mohabir R, Clusin WT. J Clin Invest. 1990; 85 (5): 1436-43
• Effect of Bay K8644 on cytosolic calcium transients and contraction in embryonic cardiac ventricular myocytes. Lee HC, Clusin WT. Pflugers Arch. 1989; 413 (3): 225-33
• Use-dependent block of single sodium channels by lidocaine in guinea pig ventricular myocytes. McDonald TV, Courtney KR, Clusin WT. Biophys J. 1989; 55 (6): 1261-6
• Effect of ischemia on calcium-dependent fluorescence transients in rabbit hearts containing indo 1. Correlation with monophasic action potentials and contraction. Lee HC, Mohabir R, Smith N, Franz MR, Clusin WT. Circulation. 1988; 78 (4): 1047-59
• Mechanism of depolarization in the ischaemic dog heart: discrepancy between T-Q potentials and potassium accumulation. Blake K, Clusin WT, Franz MR, Smith NA. J Physiol. 1988: 397 307-30
• Cytosolic calcium staircase in cultured myocardial cells. Lee HC, Clusin WT. Circ Res. 1987; 61 (6): 934-9
• Cytosolic calcium transients from the beating mammalian heart. Lee HC, Smith N, Mohabir R, Clusin WT. Proc Natl Acad Sci U S A. 1987; 84 (21): 7793-7
• What is the solution to sudden cardiac death: calcium modulation or arrhythmia clinics? Clusin WT, Cardiovasc Drugs Ther. 1987; 1 (4): 335-42