Publications
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Biological, clinical and population relevance of 95 loci for blood lipids.
Teslovich TM,
Musunuru K, Smith AV, Edmondson AC, Stylianou IM, Koseki M, Pirruccello JP, Ripatti S, Chasman DI, Willer CJ, Johansen CT, Fouchier SW, Isaacs A, Peloso GM, Barbalic M, Ricketts SL, Bis JC, Aulchenko YS, Thorleifsson G, Feitosa MF, Chambers J, Orho-Melander M, Melander O, Johnson T, Li X, Guo X, Li M, Shin Cho Y, Jin Go M, Jin Kim Y, Lee JY, Park T, Kim K, Sim X, Twee-Hee Ong R, Croteau-Chonka DC, Lange LA, Smith JD, Song K, Hua Zhao J, Yuan X, Luan J, Lamina C, Ziegler A, Zhang W, Zee RY, Wright AF, Witteman JC, Wilson JF, Willemsen G, Wichmann HE, Whitfield JB, Waterworth DM, Wareham NJ, Waeber G, Vollenweider P, Voight BF, Vitart V, Uitterlinden AG, Uda M, Tuomilehto J, Thompson JR, Tanaka T, Surakka I, Stringham HM, Spector TD, Soranzo N, Smit JH, Sinisalo J, Silander K, Sijbrands EJ, Scuteri A, Scott J, Schlessinger D, Sanna S, Salomaa V, Saharinen J, Sabatti C, Ruokonen A, Rudan I, Rose LM, Roberts R, Rieder M, Psaty BM, Pramstaller PP, Pichler I, Perola M, Penninx BW, Pedersen NL, Pattaro C, Parker AN, Pare G, Oostra BA, O'Donnell CJ, Nieminen MS, Nickerson DA, Montgomery GW, Meitinger T, McPherson R, McCarthy MI, McArdle W, Masson D, Martin NG, Marroni F, Mangino M, Magnusson PK, Lucas G, Luben R, Loos RJ, Lokki ML, Lettre G, Langenberg C, Launer LJ, Lakatta EG, Laaksonen R, Kyvik KO, Kronenberg F, König IR, Khaw KT, Kaprio J, Kaplan LM, Johansson A, Jarvelin MR, Janssens AC, Ingelsson E, Igl W, Kees Hovingh G, Hottenga JJ, Hofman A, Hicks AA, Hengstenberg C, Heid IM, Hayward C, Havulinna AS, Hastie ND, Harris TB, Haritunians T, Hall AS, Gyllensten U, Guiducci C, Groop LC, Gonzalez E, Gieger C, Freimer NB, Ferrucci L, Erdmann J, Elliott P, Ejebe KG, Döring A, Dominiczak AF, Demissie S, Deloukas P, de Geus EJ, de Faire U, Crawford G, Collins FS, Chen YD, Caulfield MJ, Campbell H, Burtt NP, Bonnycastle LL, Boomsma DI, Boekholdt SM, Bergman RN, Barroso I, Bandinelli S, Ballantyne CM, Assimes TL, Quertermous T, Altshuler D, Seielstad M, Wong TY, Tai ES, Feranil AB, Kuzawa CW, Adair LS, Taylor HA, Borecki IB, Gabriel SB, Wilson JG, Holm H, Thorsteinsdottir U, Gudnason V, Krauss RM, Mohlke KL, Ordovas JM, Munroe PB, Kooner JS, Tall AR, Hegele RA, Kastelein JJ, Schadt EE, Rotter JI, Boerwinkle E, Strachan DP, Mooser V, Stefansson K, Reilly MP, Samani NJ, Schunkert H, Cupples LA, Sandhu MS, Ridker PM, Rader DJ, van Duijn CM, Peltonen L, Abecasis GR, Boehnke M, Kathiresan S.
Nature.
2010;
466
(7307):
707-13
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Genome-wide meta-analyses identify multiple loci associated with smoking behavior.
Nat Genet.
2010;
42
(5):
441-7
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Hundreds of variants clustered in genomic loci and biological pathways affect human height.
Lango Allen H,
Estrada K, Lettre G, Berndt SI, Weedon MN, Rivadeneira F, Willer CJ, Jackson AU, Vedantam S, Raychaudhuri S, Ferreira T, Wood AR, Weyant RJ, Segrè AV, Speliotes EK, Wheeler E, Soranzo N, Park JH, Yang J, Gudbjartsson D, Heard-Costa NL, Randall JC, Qi L, Vernon Smith A, Mägi R, Pastinen T, Liang L, Heid IM, Luan J, Thorleifsson G, Winkler TW, Goddard ME, Sin Lo K, Palmer C, Workalemahu T, Aulchenko YS, Johansson A, Zillikens MC, Feitosa MF, Esko T, Johnson T, Ketkar S, Kraft P, Mangino M, Prokopenko I, Absher D, Albrecht E, Ernst F, Glazer NL, Hayward C, Hottenga JJ, Jacobs KB, Knowles JW, Kutalik Z, Monda KL, Polasek O, Preuss M, Rayner NW, Robertson NR, Steinthorsdottir V, Tyrer JP, Voight BF, Wiklund F, Xu J, Zhao JH, Nyholt DR, Pellikka N, Perola M, Perry JR, Surakka I, Tammesoo ML, Altmaier EL, Amin N, Aspelund T, Bhangale T, Boucher G, Chasman DI, Chen C, Coin L, Cooper MN, Dixon AL, Gibson Q, Grundberg E, Hao K, Juhani Junttila M, Kaplan LM, Kettunen J, König IR, Kwan T, Lawrence RW, Levinson DF, Lorentzon M, McKnight B, Morris AP, Müller M, Suh Ngwa J, Purcell S, Rafelt S, Salem RM, Salvi E, Sanna S, Shi J, Sovio U, Thompson JR, Turchin MC, Vandenput L, Verlaan DJ, Vitart V, White CC, Ziegler A, Almgren P, Balmforth AJ, Campbell H, Citterio L, De Grandi A, Dominiczak A, Duan J, Elliott P, Elosua R, Eriksson JG, Freimer NB, Geus EJ, Glorioso N, Haiqing S, Hartikainen AL, Havulinna AS, Hicks AA, Hui J, Igl W, Illig T, Jula A, Kajantie E, Kilpeläinen TO, Koiranen M, Kolcic I, Koskinen S, Kovacs P, Laitinen J, Liu J, Lokki ML, Marusic A, Maschio A, Meitinger T, Mulas A, Paré G, Parker AN, Peden JF, Petersmann A, Pichler I, Pietiläinen KH, Pouta A, Ridderstråle M, Rotter JI, Sambrook JG, Sanders AR, Schmidt CO, Sinisalo J, Smit JH, Stringham HM, Bragi Walters G, Widen E, Wild SH, Willemsen G, Zagato L, Zgaga L, Zitting P, Alavere H, Farrall M, McArdle WL, Nelis M, Peters MJ, Ripatti S, van Meurs JB, Aben KK, Ardlie KG, Beckmann JS, Beilby JP, Bergman RN, Bergmann S, Collins FS, Cusi D, den Heijer M, Eiriksdottir G, Gejman PV, Hall AS, Hamsten A, Huikuri HV, Iribarren C, Kähönen M, Kaprio J, Kathiresan S, Kiemeney L, Kocher T, Launer LJ, Lehtimäki T, Melander O, Mosley TH, Musk AW, Nieminen MS, O'Donnell CJ, Ohlsson C, Oostra B, Palmer LJ, Raitakari O, Ridker PM, Rioux JD, Rissanen A, Rivolta C, Schunkert H, Shuldiner AR, Siscovick DS, Stumvoll M, Tönjes A, Tuomilehto J, van Ommen GJ, Viikari J, Heath AC, Martin NG, Montgomery GW, Province MA, Kayser M, Arnold AM, Atwood LD, Boerwinkle E, Chanock SJ, Deloukas P, Gieger C, Grönberg H, Hall P, Hattersley AT, Hengstenberg C, Hoffman W, Lathrop GM, Salomaa V, Schreiber S, Uda M, Waterworth D, Wright AF, Assimes TL, Barroso I, Hofman A, Mohlke KL, Boomsma DI, Caulfield MJ, Cupples LA, Erdmann J, Fox CS, Gudnason V, Gyllensten U, Harris TB, Hayes RB, Jarvelin MR, Mooser V, Munroe PB, Ouwehand WH, Penninx BW, Pramstaller PP, Quertermous T, Rudan I, Samani NJ, Spector TD, Völzke H, Watkins H, Wilson JF.
Nature.
2010;
467
(7317):
832-8
-
Upregulation of the apelin-APJ pathway promotes neointima formation in the carotid ligation model in mouse.
Kojima Y,
Kundu RK, Cox CM, Leeper NJ, Anderson JA, Chun HJ, Ali ZA, Ashley EA, Krieg PA, Quertermous T.
Cardiovasc Res.
2010;
87
(1):
156-65
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Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis.
Chun HJ,
Ali ZA, Kojima Y, Kundu RK, Sheikh AY, Agrawal R, Zheng L, Leeper NJ, Pearl NE, Patterson AJ, Anderson JP, Tsao PS, Lenardo MJ, Ashley EA, Quertermous T.
J Clin Invest.
2008;
118
(10):
3343-54
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Network analysis of human in-stent restenosis.
Ashley EA,
Ferrara R, King JY, Vailaya A, Kuchinsky A, He X, Byers B, Gerckens U, Oblin S, Tsalenko A, Soito A, Spin JM, Tabibiazar R, Connolly AJ, Simpson JB, Grube E, Quertermous T.
Circulation.
2006;
114
(24):
2644-54
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Proteomic profiles of serum inflammatory markers accurately predict atherosclerosis in mice.
Tabibiazar R,
Wagner RA, Deng A, Tsao PS, Quertermous T.
Physiol Genomics.
2006;
25
(2):
194-202
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Genetic structure, self-identified race/ethnicity, and confounding in case-control association studies.
Tang H,
Quertermous T, Rodriguez B, Kardia SL, Zhu X, Brown A, Pankow JS, Province MA, Hunt SC, Boerwinkle E, Schork NJ, Risch NJ.
Am J Hum Genet.
2005;
76
(2):
268-75
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Signature patterns of gene expression in mouse atherosclerosis and their correlation to human coronary disease.
Tabibiazar R,
Wagner RA, Ashley EA, King JY, Ferrara R, Spin JM, Sanan DA, Narasimhan B, Tibshirani R, Tsao PS, Efron B, Quertermous T.
Physiol Genomics.
2005;
22
(2):
213-26
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The endogenous peptide apelin potently improves cardiac contractility and reduces cardiac loading in vivo.
Ashley EA,
Powers J, Chen M, Kundu R, Finsterbach T, Caffarelli A, Deng A, Eichhorn J, Mahajan R, Agrawal R, Greve J, Robbins R, Patterson AJ, Bernstein D, Quertermous T.
Cardiovasc Res.
2005;
65
(1):
73-82
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Apelin enhances directed cardiac differentiation of mouse and human embryonic stem cells.
Wang IN,
Wang X, Ge X, Anderson J, Ho M, Ashley E, Liu J, Butte MJ, Yazawa M, Dolmetsch RE, Quertermous T, Yang PC.
PLoS One.
2012;
7
(6):
e38328
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Common ALDH2 genetic variants predict development of hypertension in the SAPPHIRe prospective cohort: gene-environmental interaction with alcohol consumption.
Chang YC,
Chiu YF, Lee IT, Ho LT, Hung YJ, Hsiung CA, Quertermous T, Donlon T, Lee WJ, Lee PC, Chen CH, Mochly-Rosen D, Chuang LM.
BMC Cardiovasc Disord.
2012:
12
58
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Erratum to: Genetic variation in the carbonyl reductase 3 gene confers risk of type 2 diabetes and insulin resistance: a potential regulator of adipogenesis.
Chang YC,
Liu PH, Tsai YC, Chiu YF, Shih SR, Ho LT, Lee WJ, Lu CH, Quertermous T, Curb JD, Lee WJ, Lee PC, He YH, Yeh JI, Hwang JJ, Tsai SH, Chuang LM.
J Mol Med (Berl).
2012;
90
(7):
859
-
FGD5 mediates proangiogenic action of vascular endothelial growth factor in human vascular endothelial cells.
Kurogane Y,
Miyata M, Kubo Y, Nagamatsu Y, Kundu RK, Uemura A, Ishida T, Quertermous T, Hirata K, Rikitake Y.
Arterioscler Thromb Vasc Biol.
2012;
32
(4):
988-96
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Replication of genome-wide association signals of type 2 diabetes in Han Chinese in a prospective cohort.
Chang YC,
Chiu YF, Liu PH, Shih KC, Lin MW, Sheu WH, Quertermous T, Curb JD, Hsiung CA, Lee WJ, Lee PC, Chen YT, Chuang LM.
Clin Endocrinol (Oxf).
2012;
76
(3):
365-72
-
The angiogenic factor Del1 prevents apoptosis of endothelial cells through integrin binding.
Wang Z,
Kundu RK, Longaker MT, Quertermous T, Yang GP.
Surgery.
2012;
151
(2):
296-305
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The effects of the renin-angiotensin-aldosterone system gene polymorphisms on insulin resistance in hypertensive families.
Hsiao CF,
Sheu WW, Hung YJ, Lin MW, Curb D, Ranadex K, Quertermous T, Chen YM, Chen IY, Wu KD.
J Renin Angiotensin Aldosterone Syst.
2012;
13
(4):
446-54
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A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.
Kraja AT,
Vaidya D, Pankow JS, Goodarzi MO, Assimes TL, Kullo IJ, Sovio U, Mathias RA, Sun YV, Franceschini N, Absher D, Li G, Zhang Q, Feitosa MF, Glazer NL, Haritunians T, Hartikainen AL, Knowles JW, North KE, Iribarren C, Kral B, Yanek L, O'Reilly PF, McCarthy MI, Jaquish C, Couper DJ, Chakravarti A, Psaty BM, Becker LC, Province MA, Boerwinkle E, Quertermous T, Palotie L, Jarvelin MR, Becker DM, Kardia SL, Rotter JI, Chen YD, Borecki IB.
Diabetes.
2011;
60
(4):
1329-39
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Apelin decreases lipolysis via G(q), G(i), and AMPK-Dependent Mechanisms.
Yue P,
Jin H, Xu S, Aillaud M, Deng AC, Azuma J, Kundu RK, Reaven GM, Quertermous T, Tsao PS.
Endocrinology.
2011;
152
(1):
59-68
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Cardiac pressure overload hypertrophy is differentially regulated by β-adrenergic receptor subtypes.
Zhao M,
Fajardo G, Urashima T, Spin JM, Poorfarahani S, Rajagopalan V, Huynh D, Connolly A, Quertermous T, Bernstein D.
Am J Physiol Heart Circ Physiol.
2011;
301
(4):
H1461-70
-
Disruption of the apelin-APJ system worsens hypoxia-induced pulmonary hypertension.
Chandra SM,
Razavi H, Kim J, Agrawal R, Kundu RK, de Jesus Perez V, Zamanian RT, Quertermous T, Chun HJ.
Arterioscler Thromb Vasc Biol.
2011;
31
(4):
814-20
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Distribution of the number of false discoveries in large-scale family-based association testing with application to the association between PTPN1 and hypertension and obesity.
Wang WC,
Hsiung CA, Wang LC, Chuang LM, Quertermous T, Chang IS.
Hum Genet.
2011;
129
(4):
425-32
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Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
Ehret GB, Munroe PB, Rice KM, Bochud M, Johnson AD, Chasman DI, Smith AV, Tobin MD, Verwoert GC, Hwang SJ, Pihur V, Vollenweider P, O'Reilly PF, Amin N, Bragg-Gresham JL, Teumer A, Glazer NL, Launer L, Zhao JH, Aulchenko Y, Heath S, Sõber S, Parsa A, Luan J, Arora P, Dehghan A, Zhang F, Lucas G, Hicks AA, Jackson AU, Peden JF, Tanaka T, Wild SH, Rudan I, Igl W, Milaneschi Y, Parker AN, Fava C, Chambers JC, Fox ER, Kumari M, Go MJ, van der Harst P, Kao WH, Sjögren M, Vinay DG, Alexander M, Tabara Y, Shaw-Hawkins S, Whincup PH, Liu Y, Shi G, Kuusisto J, Tayo B, Seielstad M, Sim X, Nguyen KD, Lehtimäki T, Matullo G, Wu Y, Gaunt TR, Onland-Moret NC, Cooper MN, Platou CG, Org E, Hardy R, Dahgam S, Palmen J, Vitart V, Braund PS, Kuznetsova T, Uiterwaal CS, Adeyemo A, Palmas W, Campbell H, Ludwig B, Tomaszewski M, Tzoulaki I, Palmer ND, Aspelund T, Garcia M, Chang YP, O'Connell JR, Steinle NI, Grobbee DE, Arking DE, Kardia SL, Morrison AC, Hernandez D, Najjar S, McArdle WL, Hadley D, Brown MJ, Connell JM, Hingorani AD, Day IN, Lawlor DA, Beilby JP, Lawrence RW, Clarke R, Hopewell JC, Ongen H, Dreisbach AW, Li Y, Young JH, Bis JC, Kähönen M, Viikari J, Adair LS, Lee NR, Chen MH, Olden M, Pattaro C, Bolton JA, Köttgen A, Bergmann S, Mooser V, Chaturvedi N, Frayling TM, Islam M, Jafar TH, Erdmann J, Kulkarni SR, Bornstein SR, Grässler J, Groop L, Voight BF, Kettunen J, Howard P, Taylor A, Guarrera S, Ricceri F, Emilsson V, Plump A, Barroso I, Khaw KT, Weder AB, Hunt SC, Sun YV, Bergman RN, Collins FS, Bonnycastle LL, Scott LJ, Stringham HM, Peltonen L, Perola M, Vartiainen E, Brand SM, Staessen JA, Wang TJ, Burton PR, Soler Artigas M, Dong Y, Snieder H, Wang X, Zhu H, Lohman KK, Rudock ME, Heckbert SR, Smith NL, Wiggins KL, Doumatey A, Shriner D, Veldre G, Viigimaa M, Kinra S, Prabhakaran D, Tripathy V, Langefeld CD, Rosengren A, Thelle DS, Corsi AM, Singleton A, Forrester T, Hilton G, McKenzie CA, Salako T, Iwai N, Kita Y, Ogihara T, Ohkubo T, Okamura T, Ueshima H, Umemura S, Eyheramendy S, Meitinger T, Wichmann HE, Cho YS, Kim HL, Lee JY, Scott J, Sehmi JS, Zhang W, Hedblad B, Nilsson P, Smith GD, Wong A, Narisu N, Stančáková A, Raffel LJ, Yao J, Kathiresan S, O'Donnell CJ, Schwartz SM, Ikram MA, Longstreth WT, Mosley TH, Seshadri S, Shrine NR, Wain LV, Morken MA, Swift AJ, Laitinen J, Prokopenko I, Zitting P, Cooper JA, Humphries SE, Danesh J, Rasheed A, Goel A, Hamsten A, Watkins H, Bakker SJ, van Gilst WH, Janipalli CS, Mani KR, Yajnik CS, Hofman A, Mattace-Raso FU, Oostra BA, Demirkan A, Isaacs A, Rivadeneira F, Lakatta EG, Orru M, Scuteri A, Ala-Korpela M, Kangas AJ, Lyytikäinen LP, Soininen P, Tukiainen T, Würtz P, Ong RT, Dörr M, Kroemer HK, Völker U, Völzke H, Galan P, Hercberg S, Lathrop M, Zelenika D, Deloukas P, Mangino M, Spector TD, Zhai G, Meschia JF, Nalls MA, Sharma P, Terzic J, Kumar MV, Denniff M, Zukowska-Szczechowska E, Wagenknecht LE, Fowkes FG, Charchar FJ, Schwarz PE, Hayward C, Guo X, Rotimi C, Bots ML, Brand E, Samani NJ, Polase.
Nature.
2011;
478
(7367):
103-9
-
Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies.
Reilly MP,
Li M, He J, Ferguson JF, Stylianou IM, Mehta NN, Burnett MS, Devaney JM, Knouff CW, Thompson JR, Horne BD, Stewart AF, Assimes TL, Wild PS, Allayee H, Nitschke PL, Patel RS, Martinelli N, Girelli D, Quyyumi AA, Anderson JL, Erdmann J, Hall AS, Schunkert H, Quertermous T, Blankenberg S, Hazen SL, Roberts R, Kathiresan S, Samani NJ, Epstein SE, Rader DJ.
Lancet.
2011;
377
(9763):
383-92
-
In vivo bioluminescence imaging of inducible nitric oxide synthase gene expression in vascular inflammation.
Terashima M,
Ehara S, Yang E, Kosuge H, Tsao PS, Quertermous T, Contag CH, McConnell MV.
Mol Imaging Biol.
2011;
13
(6):
1061-6
-
In vivo molecular MRI of cell survival and teratoma formation following embryonic stem cell transplantation into the injured murine myocardium.
Chung J,
Kee K, Barral JK, Dash R, Kosuge H, Wang X, Weissman I, Robbins RC, Nishimura D, Quertermous T, Reijo-Pera RA, Yang PC.
Magn Reson Med.
2011;
66
(5):
1374-81
-
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.
Schunkert H,
König IR, Kathiresan S, Reilly MP, Assimes TL, Holm H, Preuss M, Stewart AF, Barbalic M, Gieger C, Absher D, Aherrahrou Z, Allayee H, Altshuler D, Anand SS, Andersen K, Anderson JL, Ardissino D, Ball SG, Balmforth AJ, Barnes TA, Becker DM, Becker LC, Berger K, Bis JC, Boekholdt SM, Boerwinkle E, Braund PS, Brown MJ, Burnett MS, Buysschaert I, Carlquist JF, Chen L, Cichon S, Codd V, Davies RW, Dedoussis G, Dehghan A, Demissie S, Devaney JM, Diemert P, Do R, Doering A, Eifert S, Mokhtari NE, Ellis SG, Elosua R, Engert JC, Epstein SE, de Faire U, Fischer M, Folsom AR, Freyer J, Gigante B, Girelli D, Gretarsdottir S, Gudnason V, Gulcher JR, Halperin E, Hammond N, Hazen SL, Hofman A, Horne BD, Illig T, Iribarren C, Jones GT, Jukema JW, Kaiser MA, Kaplan LM, Kastelein JJ, Khaw KT, Knowles JW, Kolovou G, Kong A, Laaksonen R, Lambrechts D, Leander K, Lettre G, Li M, Lieb W, Loley C, Lotery AJ, Mannucci PM, Maouche S, Martinelli N, McKeown PP, Meisinger C, Meitinger T, Melander O, Merlini PA, Mooser V, Morgan T, Mühleisen TW, Muhlestein JB, Münzel T, Musunuru K, Nahrstaedt J, Nelson CP, Nöthen MM, Olivieri O, Patel RS, Patterson CC, Peters A, Peyvandi F, Qu L, Quyyumi AA, Rader DJ, Rallidis LS, Rice C, Rosendaal FR, Rubin D, Salomaa V, Sampietro ML, Sandhu MS, Schadt E, Schäfer A, Schillert A, Schreiber S, Schrezenmeir J, Schwartz SM, Siscovick DS, Sivananthan M, Sivapalaratnam S, Smith A, Smith TB, Snoep JD, Soranzo N, Spertus JA, Stark K, Stirrups K, Stoll M, Tang WH, Tennstedt S, Thorgeirsson G, Thorleifsson G, Tomaszewski M, Uitterlinden AG, van Rij AM, Voight BF, Wareham NJ, Wells GA, Wichmann HE, Wild PS, Willenborg C, Witteman JC, Wright BJ, Ye S, Zeller T, Ziegler A, Cambien F, Goodall AH, Cupples LA, Quertermous T, März W, Hengstenberg C, Blankenberg S, Ouwehand WH, Hall AS, Deloukas P, Thompson JR, Stefansson K, Roberts R, Thorsteinsdottir U, O'Donnell CJ, McPherson R, Erdmann J, Samani NJ.
Nat Genet.
2011;
43
(4):
333-8
-
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
Heid IM,
Jackson AU, Randall JC, Winkler TW, Qi L, Steinthorsdottir V, Thorleifsson G, Zillikens MC, Speliotes EK, Mägi R, Workalemahu T, White CC, Bouatia-Naji N, Harris TB, Berndt SI, Ingelsson E, Willer CJ, Weedon MN, Luan J, Vedantam S, Esko T, Kilpeläinen TO, Kutalik Z, Li S, Monda KL, Dixon AL, Holmes CC, Kaplan LM, Liang L, Min JL, Moffatt MF, Molony C, Nicholson G, Schadt EE, Zondervan KT, Feitosa MF, Ferreira T, Allen HL, Weyant RJ, Wheeler E, Wood AR, Estrada K, Goddard ME, Lettre G, Mangino M, Nyholt DR, Purcell S, Vernon Smith A, Visscher PM, Yang J, McCarroll SA, Nemesh J, Voight BF, Absher D, Amin N, Aspelund T, Coin L, Glazer NL, Hayward C, Heard-Costa NL, Hottenga JJ, Johansson A, Johnson T, Kaakinen M, Kapur K, Ketkar S, Knowles JW, Kraft P, Kraja AT, Lamina C, Leitzmann MF, McKnight B, Morris AP, Ong KK, Perry JR, Peters MJ, Polasek O, Prokopenko I, Rayner NW, Ripatti S, Rivadeneira F, Robertson NR, Sanna S, Sovio U, Surakka I, Teumer A, van Wingerden S, Vitart V, Zhao JH, Cavalcanti-Proença C, Chines PS, Fisher E, Kulzer JR, Lecoeur C, Narisu N, Sandholt C, Scott LJ, Silander K, Stark K, Tammesoo ML, Teslovich TM, Timpson NJ, Watanabe RM, Welch R, Chasman DI, Cooper MN, Jansson JO, Kettunen J, Lawrence RW, Pellikka N, Perola M, Vandenput L, Alavere H, Almgren P, Atwood LD, Bennett AJ, Biffar R, Bonnycastle LL, Bornstein SR, Buchanan TA, Campbell H, Day IN, Dei M, Dörr M, Elliott P, Erdos MR, Eriksson JG, Freimer NB, Fu M, Gaget S, Geus EJ, Gjesing AP, Grallert H, Gräßler J, Groves CJ, Guiducci C, Hartikainen AL, Hassanali N, Havulinna AS, Herzig KH, Hicks AA, Hui J, Igl W, Jousilahti P, Jula A, Kajantie E, Kinnunen L, Kolcic I, Koskinen S, Kovacs P, Kroemer HK, Krzelj V, Kuusisto J, Kvaloy K, Laitinen J, Lantieri O, Lathrop GM, Lokki ML, Luben RN, Ludwig B, McArdle WL, McCarthy A, Morken MA, Nelis M, Neville MJ, Paré G, Parker AN, Peden JF, Pichler I, Pietiläinen KH, Platou CG, Pouta A, Ridderstråle M, Samani NJ, Saramies J, Sinisalo J, Smit JH, Strawbridge RJ, Stringham HM, Swift AJ, Teder-Laving M, Thomson B, Usala G, van Meurs JB, van Ommen GJ, Vatin V, Volpato CB, Wallaschofski H, Walters GB, Widen E, Wild SH, Willemsen G, Witte DR, Zgaga L, Zitting P, Beilby JP, James AL, Kähönen M, Lehtimäki T, Nieminen MS, Ohlsson C, Palmer LJ, Raitakari O, Ridker PM, Stumvoll M, Tönjes A, Viikari J, Balkau B, Ben-Shlomo Y, Bergman RN, Boeing H, Smith GD, Ebrahim S, Froguel P, Hansen T, Hengstenberg C, Hveem K, Isomaa B, Jørgensen T, Karpe F, Khaw KT, Laakso M, Lawlor DA, Marre M, Meitinger T, Metspalu A, Midthjell K, Pedersen O, Salomaa V, Schwarz PE, Tuomi T, Tuomilehto J, Valle TT, Wareham NJ, Arnold AM, Beckmann JS, Bergmann S, Boerwinkle E, Boomsma DI, Caulfield MJ, Collins FS, Eiriksdottir G, Gudnason V, Gyllensten U, Hamsten A, Hattersley AT, Hofman A, Hu FB, Illig T, Iribarren C, Jarvelin MR, Kao WH, Kaprio J, Launer LJ, Munroe PB, Oostra B, Penninx BW, Pramstaller PP, Psaty BM, Quertermous T, Rissanen A, Rudan I, Shuldiner AR, Soranzo.
Nat Genet.
2011;
43
(11):
1164
-
MicroRNA-26a is a novel regulator of vascular smooth muscle cell function.
Leeper NJ,
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Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
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Nat Genet.
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Chromatin remodeling pathways in smooth muscle cell differentiation, and evidence for an integral role for p300.
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PLoS One.
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Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-wide association meta-analysis involving more than 22 000 cases and 60 000 controls.
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Diabetes.
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Endothelial cell-selective adhesion molecule modulates atherosclerosis through plaque angiogenesis and monocyte-endothelial interaction.
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Impact of combined deficiency of hepatic lipase and endothelial lipase on the metabolism of both high-density lipoproteins and apolipoprotein B-containing lipoproteins.
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Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies.
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Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
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Nat Genet.
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Persistent donor cell gene expression among human induced pluripotent stem cells contributes to differences with human embryonic stem cells.
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PLoS One.
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Role of endothelial cell-selective adhesion molecule in hematogeneous metastasis.
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Microvasc Res.
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Sex-specific genetic architecture of human fatness in Chinese: the SAPPHIRe Study.
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Hum Genet.
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Admixture mapping of quantitative trait loci for blood lipids in African-Americans.
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Hum Mol Genet.
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Apelin prevents aortic aneurysm formation by inhibiting macrophage inflammation.
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Am J Physiol Heart Circ Physiol.
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Characterizing the admixed African ancestry of African Americans.
Zakharia F,
Basu A, Absher D, Assimes TL, Go AS, Hlatky MA, Iribarren C, Knowles JW, Li J, Narasimhan B, Sidney S, Southwick A, Myers RM, Quertermous T, Risch N, Tang H.
Genome Biol.
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Endogenous regulation of cardiovascular function by apelin-APJ.
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Am J Physiol Heart Circ Physiol.
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Endothelial cell specific adhesion molecule (ESAM) localizes to platelet-platelet contacts and regulates thrombus formation in vivo.
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Identification of ARIA regulating endothelial apoptosis and angiogenesis by modulating proteasomal degradation of cIAP-1 and cIAP-2.
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Insulin resistance independently predicts the progression of coronary artery calcification.
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Ontogeny of apelin and its receptor in the rodent gastrointestinal tract.
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Peroxisome proliferator-activated receptor gamma polymorphisms and coronary heart disease.
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Targeted inactivation of endothelial lipase attenuates lung allergic inflammation through raising plasma HDL level and inhibiting eosinophil infiltration.
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The adhesion molecule esam1 is a novel hematopoietic stem cell marker.
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A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease.
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A novel platform device for rodent echocardiography.
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Apelin-APJ signaling in retinal angiogenesis.
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Del-1, an endogenous leukocyte-endothelial adhesion inhibitor, limits inflammatory cell recruitment.
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Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CAD.
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Increased rate of hair regrowth in mice with constitutive overexpression of Del1.
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Molecular and physiological characterization of RV remodeling in a murine model of pulmonary stenosis.
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The negative correlation between plasma adiponectin and blood pressure depends on obesity: a family-based association study in SAPPHIRe.
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Transcriptome alteration in the diabetic heart by rosiglitazone: implications for cardiovascular mortality.
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Circulating chemokines accurately identify individuals with clinically significant atherosclerotic heart disease.
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Endothelial lipase is increased by inflammation and promotes LDL uptake in macrophages.
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Frontiers in nephrology: genomic approaches to understanding the molecular basis of atherosclerosis.
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Genetic susceptibility to peripheral arterial disease: a dark corner in vascular biology.
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HIF-1 regulates hypoxia- and insulin-induced expression of apelin in adipocytes.
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Hepatic proprotein convertases modulate HDL metabolism.
Jin W,
Wang X, Millar JS, Quertermous T, Rothblat GH, Glick JM, Rader DJ.
Cell Metab.
2007;
6
(2):
129-36
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Heritability of left ventricular mass in Japanese families living in Hawaii: the SAPPHIRe Study.
Assimes TL,
Narasimhan B, Seto TB, Yoon S, Curb JD, Olshen RA, Quertermous T.
J Hypertens.
2007;
25
(5):
985-92
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Matrix metalloproteinase circulating levels, genetic polymorphisms, and susceptibility to acute myocardial infarction among patients with coronary artery disease.
Hlatky MA,
Ashley E, Quertermous T, Boothroyd DB, Ridker P, Southwick A, Myers RM, Iribarren C, Fortmann SP, Go AS.
Am Heart J.
2007;
154
(6):
1043-51
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Polymorphisms in hypoxia inducible factor 1 and the initial clinical presentation of coronary disease.
Hlatky MA,
Quertermous T, Boothroyd DB, Priest JR, Glassford AJ, Myers RM, Fortmann SP, Iribarren C, Tabor HK, Assimes TL, Tibshirani RJ, Go AS.
Am Heart J.
2007;
154
(6):
1035-42
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An updated meta-analysis of genome scans for hypertension and blood pressure in the NHLBI Family Blood Pressure Program (FBPP).
Wu X,
Kan D, Province M, Quertermous T, Rao DC, Chang C, Mosley TH, Curb D, Boerwinkle E, Cooper RS.
Am J Hypertens.
2006;
19
(1):
122-7
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Differences in vascular bed disease susceptibility reflect differences in gene expression response to atherogenic stimuli.
Deng DX,
Tsalenko A, Vailaya A, Ben-Dor A, Kundu R, Estay I, Tabibiazar R, Kincaid R, Yakhini Z, Bruhn L, Quertermous T.
Circ Res.
2006;
98
(2):
200-8
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Dual in vivo magnetic resonance evaluation of magnetically labeled mouse embryonic stem cells and cardiac function at 1.5 t.
Arai T,
Kofidis T, Bulte JW, de Bruin J, Venook RD, Berry GJ, Mcconnell MV, Quertermous T, Robbins RC, Yang PC.
Magn Reson Med.
2006;
55
(1):
203-9
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Glia maturation factor-gamma is preferentially expressed in microvascular endothelial and inflammatory cells and modulates actin cytoskeleton reorganization.
Ikeda K,
Kundu RK, Ikeda S, Kobara M, Matsubara H, Quertermous T.
Circ Res.
2006;
99
(4):
424-33
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Metabolic syndrome and early-onset coronary artery disease: is the whole greater than its parts?
Iribarren C,
Go AS, Husson G, Sidney S, Fair JM, Quertermous T, Hlatky MA, Fortmann SP.
J Am Coll Cardiol.
2006;
48
(9):
1800-7
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Molecular signatures determining coronary artery and saphenous vein smooth muscle cell phenotypes: distinct responses to stimuli.
Deng DX,
Spin JM, Tsalenko A, Vailaya A, Ben-Dor A, Yakhini Z, Tsao P, Bruhn L, Quertermous T.
Arterioscler Thromb Vasc Biol.
2006;
26
(5):
1058-65
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Opposing cardiovascular roles for the angiotensin and apelin signaling pathways.
Ashley E,
Chun HJ, Quertermous T.
J Mol Cell Cardiol.
2006;
41
(5):
778-81
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Statin and beta-blocker therapy and the initial presentation of coronary heart disease.
Go AS,
Iribarren C, Chandra M, Lathon PV, Fortmann SP, Quertermous T, Hlatky MA.
Ann Intern Med.
2006;
144
(4):
229-38
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The impact of data quality on the identification of complex disease genes: experience from the Family Blood Pressure Program.
Chang YP,
Kim JD, Schwander K, Rao DC, Miller MB, Weder AB, Cooper RS, Schork NJ, Province MA, Morrison AC, Kardia SL, Quertermous T, Chakravarti A.
Eur J Hum Genet.
2006;
14
(4):
469-77
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Transcriptional profiling of reporter genes used for molecular imaging of embryonic stem cell transplantation.
Wu JC,
Spin JM, Cao F, Lin S, Xie X, Gheysens O, Chen IY, Sheikh AY, Robbins RC, Tsalenko A, Gambhir SS, Quertermous T.
Physiol Genomics.
2006;
25
(1):
29-38
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Admixture mapping for hypertension loci with genome-scan markers.
Zhu X,
Luke A, Cooper RS, Quertermous T, Hanis C, Mosley T, Gu CC, Tang H, Rao DC, Risch N, Weder A.
Nat Genet.
2005;
37
(2):
177-81
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An autosomal genome-wide scan for loci linked to pre-diabetic phenotypes in nondiabetic Chinese subjects from the Stanford Asia-Pacific Program of Hypertension and Insulin Resistance Family Study.
Chiu YF,
Chuang LM, Hsiao CF, Hung YJ, Lin MW, Chen YT, Grove J, Jorgenson E, Quertermous T, Risch N, Hsiung CA.
Diabetes.
2005;
54
(4):
1200-6
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An evaluation of the metabolic syndrome in a large multi-ethnic study: the Family Blood Pressure Program.
Kraja AT,
Rao DC, Weder AB, Mosley TH, Turner ST, Hsiung CA, Quertermous T, Cooper R, Curb JD, Province MA.
Nutr Metab (Lond).
2005:
2
17
-
Genome-wide expression dynamics during mouse embryonic development reveal similarities to Drosophila development.
Wagner RA,
Tabibiazar R, Liao A, Quertermous T.
Dev Biol.
2005;
288
(2):
595-611
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Genome-wide linkage scans for fasting glucose, insulin, and insulin resistance in the National Heart, Lung, and Blood Institute Family Blood Pressure Program: evidence of linkages to chromosome 7q36 and 19q13 from meta-analysis.
An P,
Freedman BI, Hanis CL, Chen YD, Weder AB, Schork NJ, Boerwinkle E, Province MA, Hsiung CA, Wu X, Quertermous T, Rao DC.
Diabetes.
2005;
54
(3):
909-14
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Increased expression of endothelial lipase in rat models of hypertension.
Shimokawa Y,
Hirata K, Ishida T, Kojima Y, Inoue N, Quertermous T, Yokoyama M.
Cardiovasc Res.
2005;
66
(3):
594-600
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Mouse strain-specific differences in vascular wall gene expression and their relationship to vascular disease.
Tabibiazar R,
Wagner RA, Spin JM, Ashley EA, Narasimhan B, Rubin EM, Efron B, Tsao PS, Tibshirani R, Quertermous T.
Arterioscler Thromb Vasc Biol.
2005;
25
(2):
302-8
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Myocardial restoration with embryonic stem cell bioartificial tissue transplantation.
Kofidis T,
de Bruin JL, Hoyt G, Ho Y, Tanaka M, Yamane T, Lebl DR, Swijnenburg RJ, Chang CP, Quertermous T, Robbins RC.
J Heart Lung Transplant.
2005;
24
(6):
737-44
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Overexpression of the Del1 gene causes dendritic branching in the mouse mesentery.
Hidai C,
Kawana M, Habu K, Kazama H, Kawase Y, Iwata T, Suzuki H, Quertermous T, Kokubun S.
Anat Rec A Discov Mol Cell Evol Biol.
2005;
287
(2):
1165-75
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Pathway analysis of coronary atherosclerosis.
King JY,
Ferrara R, Tabibiazar R, Spin JM, Chen MM, Kuchinsky A, Vailaya A, Kincaid R, Tsalenko A, Deng DX, Connolly A, Zhang P, Yang E, Watt C, Yakhini Z, Ben-Dor A, Adler A, Bruhn L, Tsao P, Quertermous T, Ashley EA.
Physiol Genomics.
2005;
23
(1):
103-18
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Platelet endothelial aggregation receptor 1 (PEAR1), a novel epidermal growth factor repeat-containing transmembrane receptor, participates in platelet contact-induced activation.
Nanda N,
Bao M, Lin H, Clauser K, Komuves L, Quertermous T, Conley PB, Phillips DR, Hart MJ.
J Biol Chem.
2005;
280
(26):
24680-9
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Two major QTLs and several others relate to factors of metabolic syndrome in the family blood pressure program.
Kraja AT,
Rao DC, Weder AB, Cooper R, Curb JD, Hanis CL, Turner ST, de Andrade M, Hsiung CA, Quertermous T, Zhu X, Province MA.
Hypertension.
2005;
46
(4):
751-7
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Biethnic comparisons of autosomal genomic scan for loci linked to plasma adiponectin in populations of Chinese and Japanese origin.
Chuang LM,
Chiu YF, Sheu WH, Hung YJ, Ho LT, Grove J, Rodriguez B, Quertermous T, Chen YD, Hsiung CA, Tai TY.
J Clin Endocrinol Metab.
2004;
89
(11):
5772-8
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Developmental endothelial locus-1 (Del-1), a novel angiogenic protein: its role in ischemia.
Ho HK,
Jang JJ, Kaji S, Spektor G, Fong A, Yang P, Hu BS, Schatzman R, Quertermous T, Cooke JP.
Circulation.
2004;
109
(10):
1314-9
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Endothelial lipase is synthesized by hepatic and aorta endothelial cells and its expression is altered in apoE-deficient mice.
Yu KC,
David C, Kadambi S, Stahl A, Hirata K, Ishida T, Quertermous T, Cooper AD, Choi SY.
J Lipid Res.
2004;
45
(9):
1614-23
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Endothelial lipase modulates monocyte adhesion to the vessel wall. A potential role in inflammation.
Kojma Y,
Hirata K, Ishida T, Shimokawa Y, Inoue N, Kawashima S, Quertermous T, Yokoyama M.
J Biol Chem.
2004;
279
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54032-8
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Endothelial lipase modulates susceptibility to atherosclerosis in apolipoprotein-E-deficient mice.
Ishida T,
Choi SY, Kundu RK, Spin J, Yamashita T, Hirata K, Kojima Y, Yokoyama M, Cooper AD, Quertermous T.
J Biol Chem.
2004;
279
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45085-92
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Genome-wide expression profiling of a cardiac pressure overload model identifies major metabolic and signaling pathway responses.
Wagner RA,
Tabibiazar R, Powers J, Bernstein D, Quertermous T.
J Mol Cell Cardiol.
2004;
37
(6):
1159-70
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Molecular cloning of nonsecreted endothelial cell-derived lipase isoforms.
Ishida T,
Zheng Z, Dichek HL, Wang H, Moreno I, Yang E, Kundu RK, Talbi S, Hirata K, Leung LL, Quertermous T.
Genomics.
2004;
83
(1):
24-33
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Molecular isolation and characterization of a soluble isoform of activated leukocyte cell adhesion molecule that modulates endothelial cell function.
Ikeda K,
Quertermous T.
J Biol Chem.
2004;
279
(53):
55315-23
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Physical inactivity is an important lifestyle determinant of insulin resistance in hypertensive patients.
Hwu CM,
Hsiao CF, Kuo SW, Wu KD, Ting CT, Quertermous T, Rodriguez B, Chen I, Grove J, Chen PY, Hoo LT.
Blood Press.
2004;
13
(6):
355-61
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Transcriptional profiling of in vitro smooth muscle cell differentiation identifies specific patterns of gene and pathway activation.
Spin JM,
Nallamshetty S, Tabibiazar R, Ashley EA, King JY, Chen M, Tsao PS, Quertermous T.
Physiol Genomics.
2004;
19
(3):
292-302
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Tree-structured supervised learning and the genetics of hypertension.
Huang J,
Lin A, Narasimhan B, Quertermous T, Hsiung CA, Ho LT, Grove JS, Olivier M, Ranade K, Risch NJ, Olshen RA.
Proc Natl Acad Sci U S A.
2004;
101
(29):
10529-34
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Comparison of developmental endothelial locus-1 angiogenic factor with vascular endothelial growth factor in a porcine model of cardiac ischemia.
Kown MH,
Suzuki T, Koransky ML, Penta K, Sakamoto G, Jahncke CL, Carter AJ, Quertermous T, Robbins RC.
Ann Thorac Surg.
2003;
76
(4):
1246-51
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Endothelial lipase is a major determinant of HDL level.
Ishida T,
Choi S, Kundu RK, Hirata K, Rubin EM, Cooper AD, Quertermous T.
J Clin Invest.
2003;
111
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347-55
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FGF-1 enhanced cardiogenesis in differentiating embryonal carcinoma cell cultures, which was opposite to the effect of FGF-2.
Hidai C,
Masako O, Ikeda H, Nagashima H, Matsuoka R, Quertermous T, Kasanuki H, Kokubun S, Kawana M.
J Mol Cell Cardiol.
2003;
35
(4):
421-5
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Genetic epistasis of adiponectin and PPARgamma2 genotypes in modulation of insulin sensitivity: a family-based association study.
Yang WS,
Hsiung CA, Ho LT, Chen YT, He CT, Curb JD, Grove J, Quertermous T, Chen YD, Kuo SS, Chuang LM.
Diabetologia.
2003;
46
(7):
977-83
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Identification of endothelial cell genes by combined database mining and microarray analysis.
Ho M,
Yang E, Matcuk G, Deng D, Sampas N, Tsalenko A, Tabibiazar R, Zhang Y, Chen M, Talbi S, Ho YD, Wang J, Tsao PS, Ben-Dor A, Yakhini Z, Bruhn L, Quertermous T.
Physiol Genomics.
2003;
13
(3):
249-62
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Immunohistochemical localization of endothelial cell-derived lipase in atherosclerotic human coronary arteries.
Azumi H,
Hirata K, Ishida T, Kojima Y, Rikitake Y, Takeuchi S, Inoue N, Kawashima S, Hayashi Y, Itoh H, Quertermous T, Yokoyama M.
Cardiovasc Res.
2003;
58
(3):
647-54
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Neovascularization of ischemic tissues by gene delivery of the extracellular matrix protein Del-1.
Zhong J,
Eliceiri B, Stupack D, Penta K, Sakamoto G, Quertermous T, Coleman M, Boudreau N, Varner JA.
J Clin Invest.
2003;
112
(1):
30-41
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Novel role for the potent endogenous inotrope apelin in human cardiac dysfunction.
Chen MM,
Ashley EA, Deng DX, Tsalenko A, Deng A, Tabibiazar R, Ben-Dor A, Fenster B, Yang E, King JY, Fowler M, Robbins R, Johnson FL, Bruhn L, McDonagh T, Dargie H, Yakhini Z, Tsao PS, Quertermous T.
Circulation.
2003;
108
(12):
1432-9
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Sagittal abdominal diameter is associated with insulin sensitivity in Chinese hypertensive patients and their siblings.
Hwu CM,
Hsiao CF, Sheu WH, Pei D, Tai TY, Quertermous T, Rodriguez B, Pratt R, Chen YD, Ho LT.
J Hum Hypertens.
2003;
17
(3):
193-8
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Targeted disruption of endothelial cell-selective adhesion molecule inhibits angiogenic processes in vitro and in vivo.
Ishida T,
Kundu RK, Yang E, Hirata K, Ho YD, Quertermous T.
J Biol Chem.
2003;
278
(36):
34598-604
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Transcriptional profiling of the heart reveals chamber-specific gene expression patterns.
Tabibiazar R,
Wagner RA, Liao A, Quertermous T.
Circ Res.
2003;
93
(12):
1193-201
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Use of high throughput genomic tools for the study of endothelial cell biology.
Tabibiazar R,
Quertermous T.
Lymphat Res Biol.
2003;
1
(2):
133-45
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Del1 mediates VSMC adhesion, migration, and proliferation through interaction with integrin alpha(v)beta(3).
Rezaee M,
Penta K, Quertermous T.
Am J Physiol Heart Circ Physiol.
2002;
282
(5):
H1924-32
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Endothelial lipase: a new lipase on the block.
Choi SY,
Hirata K, Ishida T, Quertermous T, Cooper AD.
J Lipid Res.
2002;
43
(11):
1763-9
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Inducible and selective transgene expression in murine vascular endothelium.
Teng PI,
Dichiara MR, Kömüves LG, Abe K, Quertermous T, Topper JN.
Physiol Genomics.
2002;
11
(2):
99-107
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The embryonic angiogenic factor Del1 accelerates tumor growth by enhancing vascular formation.
Aoka Y,
Johnson FL, Penta K, Hirata Ki K, Hidai C, Schatzman R, Varner JA, Quertermous T.
Microvasc Res.
2002;
64
(1):
148-61
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Therapeutic lymphangiogenesis with human recombinant VEGF-C.
Szuba A,
Skobe M, Karkkainen MJ, Shin WS, Beynet DP, Rockson NB, Dakhil N, Spilman S, Goris ML, Strauss HW, Quertermous T, Alitalo K, Rockson SG.
FASEB J.
2002;
16
(14):
1985-7
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Cloning of an immunoglobulin family adhesion molecule selectively expressed by endothelial cells.
Hirata Ki,
Ishida T, Penta K, Rezaee M, Yang E, Wohlgemuth J, Quertermous T.
J Biol Chem.
2001;
276
(19):
16223-31
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Identification of an octamer element required for in vivo expression of the TIE1 gene in endothelial cells.
Boutet SC,
Quertermous T, Fadel BM.
Biochem J.
2001;
360
(Pt 1):
23-9
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NHLBI workshop report: endothelial cell phenotypes in heart, lung, and blood diseases.
Stevens T,
Rosenberg R, Aird W, Quertermous T, Johnson FL, Garcia JG, Hebbel RP, Tuder RM, Garfinkel S.
Am J Physiol Cell Physiol.
2001;
281
(5):
C1422-33
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Plating and transferring bacteriophage libraries.
Quertermous T,
Curr Protoc Mol Biol.
2001:
Chapter 6
Unit6.1
-
Production of a genomic DNA library.
Quertermous T,
Curr Protoc Mol Biol.
2001:
Chapter 5
Unit5.7
-
Purification of bacteriophage clones.
Quertermous T,
Curr Protoc Mol Biol.
2001:
Chapter 6
Unit6.5
-
Size fractionation using agarose gels.
Quertermous T,
Curr Protoc Mol Biol.
2001:
Chapter 5
Unit5.4
-
Size fractionation using sucrose gradients.
Weis JH,
Quertermous T.
Curr Protoc Mol Biol.
2001:
Chapter 5
Unit5.3
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Vezf1/DB1 is an endothelial cell-specific transcription factor that regulates expression of the endothelin-1 promoter.
Aitsebaomo J,
Kingsley-Kallesen ML, Wu Y, Quertermous T, Patterson C.
J Biol Chem.
2001;
276
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39197-205
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Cardiovascular overexpression of transforming growth factor-beta(1) causes abnormal yolk sac vasculogenesis and early embryonic death.
Agah R,
Prasad KS, Linnemann R, Firpo MT, Quertermous T, Dichek DA.
Circ Res.
2000;
86
(10):
1024-30
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Endothelial cell-specific regulation of the murine endothelin-1 gene.
Fadel BM,
Boutet SC, Quertermous T.
J Cardiovasc Pharmacol.
2000;
35
(4 Suppl 2):
S7-11
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Regulated expression of endothelial cell-derived lipase.
Hirata K,
Ishida T, Matsushita H, Tsao PS, Quertermous T.
Biochem Biophys Res Commun.
2000;
272
(1):
90-3
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Cloning of a unique lipase from endothelial cells extends the lipase gene family.
Hirata K,
Dichek HL, Cioffi JA, Choi SY, Leeper NJ, Quintana L, Kronmal GS, Cooper AD, Quertermous T.
J Biol Chem.
1999;
274
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14170-5
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Del1 induces integrin signaling and angiogenesis by ligation of alphaVbeta3.
Penta K,
Varner JA, Liaw L, Hidai C, Schatzman R, Quertermous T.
J Biol Chem.
1999;
274
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11101-9
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Octamer-dependent in vivo expression of the endothelial cell-specific TIE2 gene.
Fadel BM,
Boutet SC, Quertermous T.
J Biol Chem.
1999;
274
(29):
20376-83
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Cloning and characterization of developmental endothelial locus-1: an embryonic endothelial cell protein that binds the alphavbeta3 integrin receptor.
Hidai C,
Zupancic T, Penta K, Mikhail A, Kawana M, Quertermous EE, Aoka Y, Fukagawa M, Matsui Y, Platika D, Auerbach R, Hogan BL, Snodgrass R, Quertermous T.
Genes Dev.
1998;
12
(1):
21-33
-
Cloning of capsulin, a basic helix-loop-helix factor expressed in progenitor cells of the pericardium and the coronary arteries.
Hidai H,
Bardales R, Goodwin R, Quertermous T, Quertermous EE.
Mech Dev.
1998;
73
(1):
33-43
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Functional analysis of the endothelial cell-specific Tie2/Tek promoter identifies unique protein-binding elements.
Fadel BM,
Boutet SC, Quertermous T.
Biochem J.
1998:
330 ( Pt 1)
335-43
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Regional variability in preproEndothelin-1 gene expression in sheep pulmonary artery and lung during the onset of air-induced chronic pulmonary hypertension. Participation Of arterial smooth muscle cells.
Tchekneva E,
Quertermous T, Christman BW, Lawrence ML, Meyrick B.
J Clin Invest.
1998;
101
(6):
1389-97
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Endothelin-1 transgenic mice develop glomerulosclerosis, interstitial fibrosis, and renal cysts but not hypertension.
Hocher B,
Thöne-Reineke C, Rohmeiss P, Schmager F, Slowinski T, Burst V, Siegmund F, Quertermous T, Bauer C, Neumayer HH, Schleuning WD, Theuring F.
J Clin Invest.
1997;
99
(6):
1380-9
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Functional activity of the CFTR Cl- channel in human myocardium.
Yajima T,
Nagashima H, Tsutsumi-Sakai R, Hagiwara N, Hosoda S, Quertermous T, Kasanuki H, Kawana M.
Heart Vessels.
1997;
12
(6):
255-61
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Identification of an endothelial cell-specific regulatory region in the murine endothelin-1 gene.
Bu X,
Quertermous T.
J Biol Chem.
1997;
272
(51):
32613-22
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Endogenous endothelin-1 mediates cardiac hypertrophy and switching of myosin heavy chain gene expression in rat ventricular myocardium.
Ichikawa KI,
Hidai C, Okuda C, Kimata SI, Matsuoka R, Hosoda S, Quertermous T, Kawana M.
J Am Coll Cardiol.
1996;
27
(5):
1286-91
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Role of endothelin in a rabbit model of acute myocardial infarction: effects of receptor antagonists.
Vitola JV,
Forman MB, Holsinger JP, Kawana M, Atkinson JB, Quertermous T, Jackson EK, Murray JJ.
J Cardiovasc Pharmacol.
1996;
28
(6):
774-83
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Cooperative interaction of GATA-2 and AP1 regulates transcription of the endothelin-1 gene.
Kawana M,
Lee ME, Quertermous EE, Quertermous T.
Mol Cell Biol.
1995;
15
(8):
4225-31
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Directed endothelial differentiation of cultured embryonic yolk sac cells in vivo provides a novel cell-based system for gene therapy.
Wei Y,
Quertermous T, Wagner TE.
Stem Cells.
1995;
13
(5):
541-7
-
Genomic organization and chromosomal localization of the gene TCF15 encoding the early mesodermal basic helix-loop-helix factor bHLH-EC2.
Hidai H,
Quertermous EE, Espinosa R, LeBeau MM, Quertermous T.
Genomics.
1995;
30
(3):
598-601
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Mouse Col18a1 is expressed in a tissue-specific manner as three alternative variants and is localized in basement membrane zones.
Muragaki Y,
Timmons S, Griffith CM, Oh SP, Fadel B, Quertermous T, Olsen BR.
Proc Natl Acad Sci U S A.
1995;
92
(19):
8763-7
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Regional and maturation-associated expression of endothelin 2 in rat gastrointestinal tract.
de la Monte SM,
Quertermous T, Hong CC, Bloch KD.
J Histochem Cytochem.
1995;
43
(2):
203-9
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Cloning and characterization of a basic helix-loop-helix protein expressed in early mesoderm and the developing somites.
Quertermous EE,
Hidai H, Blanar MA, Quertermous T.
Proc Natl Acad Sci U S A.
1994;
91
(15):
7066-70
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Cosegregation of the endothelin-3 locus with blood pressure and relative heart weight in inbred Dahl rats.
Cicila GT,
Rapp JP, Bloch KD, Kurtz TW, Pravenec M, Kren V, Hong CC, Quertermous T, Ng SC.
J Hypertens.
1994;
12
(6):
643-51
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Pulmonary hypoxia increases endothelin-1 gene expression in sheep.
Donahue DM,
Lee ME, Suen HC, Quertermous T, Wain JC.
J Surg Res.
1994;
57
(2):
280-3
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The immunoreactive region in a novel autoantigen contains a nuclear localization sequence.
Bloch DB,
Rabkina D, Quertermous T, Bloch KD.
Clin Immunol Immunopathol.
1994;
72
(3):
380-9
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Effect of heavy chain signal peptide mutations and NH2-terminal chain length on binding of anti-digoxin antibodies.
Ping J,
Schildbach JF, Shaw SY, Quertermous T, Novotny J, Bruccoleri R, Margolies MN.
J Biol Chem.
1993;
268
(31):
23000-7
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High-level expression of antibody-plasminogen activator fusion proteins in hybridoma cells.
Love TW,
Quertermous T, Zavodny PJ, Runge MS, Chou CC, Mullins D, Huang PL, Schnee JM, Kestin AS, Savard CE.
Thromb Res.
1993;
69
(2):
221-9
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Structural organization and chromosomal assignment of the gene encoding the human heparin-binding epidermal growth factor-like growth factor/diphtheria toxin receptor.
Fen Z,
Dhadly MS, Yoshizumi M, Hilkert RJ, Quertermous T, Eddy RL, Shows TB, Lee ME.
Biochemistry.
1993;
32
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7932-8
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Genetic regulation of endothelin-1 in vascular endothelial cells.
Hilkert RJ,
Lee ME, Quertermous T.
Trends Cardiovasc Med.
1992 Jul-Aug;
2
(4):
129-33
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Cloning and expression of a cDNA encoding human endothelium-derived relating factor/nitric oxide synthase.
Janssens SP,
Simouchi A, Quertermous T, Bloch DB, Bloch KD.
J Biol Chem.
1992;
267
(31):
22694
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Cloning and expression of a cDNA encoding human endothelium-derived relaxing factor/nitric oxide synthase.
Janssens SP,
Shimouchi A, Quertermous T, Bloch DB, Bloch KD.
J Biol Chem.
1992;
267
(21):
14519-22
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Induction of heparin-binding epidermal growth factor-like growth factor mRNA by phorbol ester and angiotensin II in rat aortic smooth muscle cells.
Temizer DH,
Yoshizumi M, Perrella MA, Susanni EE, Quertermous T, Lee ME.
J Biol Chem.
1992;
267
(34):
24892-6
-
Tumor necrosis factor increases transcription of the heparin-binding epidermal growth factor-like growth factor gene in vascular endothelial cells.
Yoshizumi M,
Kourembanas S, Temizer DH, Cambria RP, Quertermous T, Lee ME.
J Biol Chem.
1992;
267
(14):
9467-9
-
A recombinant chimeric plasminogen activator with high affinity for fibrin has increased thrombolytic potency in vitro and in vivo.
Runge MS,
Quertermous T, Zavodny PJ, Love TW, Bode C, Freitag M, Shaw SY, Huang PL, Chou CC, Mullins D.
Proc Natl Acad Sci U S A.
1991;
88
(22):
10337-41
-
Cloning of the GATA-binding protein that regulates endothelin-1 gene expression in endothelial cells.
Lee ME,
Temizer DH, Clifford JA, Quertermous T.
J Biol Chem.
1991;
266
(24):
16188-92
-
Effect of chemical conjugation of recombinant single-chain urokinase-type plasminogen activator with monoclonal antiplatelet antibodies on platelet aggregation and on plasma clot lysis in vitro and in vivo.
Dewerchin M,
Lijnen HR, Stassen JM, De Cock F, Quertermous T, Ginsberg MH, Plow EF, Collen D.
Blood.
1991;
78
(4):
1005-18
-
Hybrid molecules: insights into plasminogen activator function.
Runge MS,
Bode C, Haber E, Quertermous T.
Mol Biol Med.
1991;
8
(2):
245-55
-
Regulation of endothelin-1 gene expression by Fos and Jun.
Lee ME,
Dhadly MS, Temizer DH, Clifford JA, Yoshizumi M, Quertermous T.
J Biol Chem.
1991;
266
(28):
19034-9
-
Stimulation of endothelin-1 gene expression by insulin in endothelial cells.
Oliver FJ,
de la Rubia G, Feener EP, Lee ME, Loeken MR, Shiba T, Quertermous T, King GL.
J Biol Chem.
1991;
266
(34):
23251-6
-
cDNA cloning and chromosomal assignment of the endothelin 2 gene: vasoactive intestinal contractor peptide is rat endothelin 2.
Bloch KD,
Hong CC, Eddy RL, Shows TB, Quertermous T.
Genomics.
1991;
10
(1):
236-42
-
Antibody-targeted thrombolytic agents.
Haber E,
Quertermous T, Matsueda GR, Runge MS, Bode C.
Jpn Circ J.
1990;
54
(4):
345-53
-
Binding of tissue-type plasminogen activator with human endothelial cell monolayers. Characterization of the high affinity interaction with plasminogen activator inhibitor-1.
Russell ME,
Quertermous T, Declerck PJ, Collen D, Haber E, Homcy CJ.
J Biol Chem.
1990;
265
(5):
2569-75
-
Expression of the potent vasoconstrictor endothelin in the human central nervous system.
Lee ME,
de la Monte SM, Ng SC, Bloch KD, Quertermous T.
J Clin Invest.
1990;
86
(1):
141-7
-
Functional analysis of the endothelin-1 gene promoter. Evidence for an endothelial cell-specific cis-acting sequence.
Lee ME,
Bloch KD, Clifford JA, Quertermous T.
J Biol Chem.
1990;
265
(18):
10446-50
-
Polymerase chain reaction cloning of L-type calcium channel sequences from the heart and the brain.
Huang P,
Temizer D, Quertermous T.
FEBS Lett.
1990;
274
(1-2):
207-13
-
Innovative approaches to plasminogen activator therapy.
Haber E,
Quertermous T, Matsueda GR, Runge MS.
Science.
1989;
243
(4887):
51-6
-
Modulation of mRNA levels for urinary- and tissue-type plasminogen activator and plasminogen activator inhibitors 1 and 2 in human fibroblasts by interleukin 1.
Michel JB,
Quertermous T.
J Immunol.
1989;
143
(3):
890-5
-
Plasminogen activators. The old and the new.
Runge MS,
Quertermous T, Haber E.
Circulation.
1989;
79
(2):
217-24
-
Recombinant antibodies possessing novel effector functions.
Love TW,
Runge MS, Haber E, Quertermous T.
Methods Enzymol.
1989:
178
515-27
-
Structural organization and chromosomal assignment of the gene encoding endothelin.
Bloch KD,
Friedrich SP, Lee ME, Eddy RL, Shows TB, Quertermous T.
J Biol Chem.
1989;
264
(18):
10851-7
-
Thrombin regulation of mRNA levels of tissue plasminogen activator and plasminogen activator inhibitor-1 in cultured human umbilical vein endothelial cells.
Dichek D,
Quertermous T.
Blood.
1989;
74
(1):
222-8
-
Variability in messenger RNA levels in human umbilical vein endothelial cells of different lineage and time in culture.
Dichek D,
Quertermous T.
In Vitro Cell Dev Biol.
1989;
25
(3 Pt 1):
289-92
-
cDNA cloning and chromosomal assignment of the gene encoding endothelin 3.
Bloch KD,
Eddy RL, Shows TB, Quertermous T.
J Biol Chem.
1989;
264
(30):
18156-61
-
Increasing selectivity of plasminogen activators with antibodies.
Runge MS,
Quertermous T, Matsueda GR, Haber E.
Clin Res.
1988;
36
(5):
501-6
-
Left ventricular ejection fraction. Physician estimates compared with gated blood pool scan measurements.
Eagle KA,
Quertermous T, Singer DE, Mulley AG, Reder VA, Boucher CA, Strauss HW, Thibault GE.
Arch Intern Med.
1988;
148
(4):
882-5
-
Nonlinkage of the T cell receptor alpha, beta, and gamma genes to systemic lupus erythematosus in multiplex families.
Wong DW,
Bentwich Z, Martinez-Tarquino C, Seidman JG, Duby AD, Quertermous T, Schur PH.
Arthritis Rheum.
1988;
31
(11):
1371-6
-
Structural integrity of the glycoprotein IIb and IIIa genes in Glanzmann thrombasthenia patients from Israel.
Russell ME,
Seligsohn U, Coller BS, Ginsberg MH, Skoglund P, Quertermous T.
Blood.
1988;
72
(5):
1833-6
-
T-cell receptor gene rearrangement and expression in human natural killer cells: natural killer activity is not dependent on the rearrangement and expression of T-cell receptor alpha, beta, or gamma genes.
Leiden JM,
Gottesdiener KM, Quertermous T, Coury L, Bray RA, Gottschalk L, Gebel H, Seidman JG, Strominger JL, Landay AL.
Immunogenetics.
1988;
27
(4):
231-8
-
Comparison of T cell receptor gene rearrangements in patients with large granular T cell leukemia and Felty's syndrome.
Freimark B,
Lanier L, Phillips J, Quertermous T, Fox R.
J Immunol.
1987;
138
(6):
1724-9
-
Construction and expression of a recombinant antibody-targeted plasminogen activator.
Schnee JM,
Runge MS, Matsueda GR, Hudson NW, Seidman JG, Haber E, Quertermous T.
Proc Natl Acad Sci U S A.
1987;
84
(19):
6904-8
-
Human T cell gamma chain joining regions and T cell development.
Quertermous T,
Strauss WM, Van Dongen JJ, Seidman JG.
J Immunol.
1987;
138
(8):
2687-90
-
Measuring the human T cell receptor gamma-chain locus.
Strauss WM,
Quertermous T, Seidman JG.
Science.
1987;
237
(4819):
1217-9
-
Provocative pattern of rearrangements of the genes for the gamma and beta chains of the T-cell receptor in human leukemias.
Goorha R,
Bunin N, Mirro J, Murphy SB, Cross AH, Behm FG, Quertermous T, Seidman J, Kitchingman GR.
Proc Natl Acad Sci U S A.
1987;
84
(13):
4547-51
-
T cell receptor-CD3 complex during early T cell differentiation. Analysis of immature T cell acute lymphoblastic leukemias (T-ALL) at DNA, RNA, and cell membrane level.
van Dongen JJ,
Quertermous T, Bartram CR, Gold DP, Wolvers-Tettero IL, Comans-Bitter WM, Hooijkaas H, Adriaansen HJ, de Klein A, Raghavachar A.
J Immunol.
1987;
138
(4):
1260-9
-
Human T-cell gamma genes contain N segments and have marked junctional variability.
Quertermous T,
Strauss W, Murre C, Dialynas DP, Strominger JL, Seidman JG.
Nature.
1986 Jul 10-16;
322
(6075):
184-7
-
Cloning and sequence analysis of complementary DNA encoding an aberrantly rearranged human T-cell gamma chain.
Dialynas DP,
Murre C, Quertermous T, Boss JM, Leiden JM, Seidman JG, Strominger JL.
Proc Natl Acad Sci U S A.
1986;
83
(8):
2619-23
-
Human T cell gamma-chain gene rearrangements in acute lymphoid and nonlymphoid leukemia: comparison with the T cell receptor beta-chain gene.
Greenberg JM,
Quertermous T, Seidman JG, Kersey JH.
J Immunol.
1986;
137
(6):
2043-9
-
Human T-cell gamma chain genes: organization, diversity, and rearrangement.
Quertermous T,
Murre C, Dialynas D, Duby AD, Strominger JL, Waldman TA, Seidman JG.
Science.
1986;
231
(4735):
252-5
-
Immunoglobulin and T-cell receptor gene rearrangement and expression in human lymphoid leukemia cells at different stages of maturation.
Davey MP,
Bongiovanni KF, Kaulfersch W, Quertermous T, Seidman JG, Hershfield MS, Kurtzberg J, Haynes BF, Davis MM, Waldmann TA.
Proc Natl Acad Sci U S A.
1986;
83
(22):
8759-63
-
Spectrum of conditions initially suggesting acute aortic dissection but with negative aortograms.
Eagle KA,
Quertermous T, Kritzer GA, Newell JB, Dinsmore R, Feldman L, DeSanctis RW.
Am J Cardiol.
1986;
57
(4):
322-6
-
T cell receptor gene rearrangements define a monoclonal T cell proliferation in patients with T cell lymphocytosis and cytopenia.
Berliner N,
Duby AD, Linch DC, Murre C, Quertermous T, Knott LJ, Azin T, Newland AC, Lewis DL, Galvin MC.
Blood.
1986;
67
(4):
914-8
-
Pacemaker failure resulting from radiation damage.
Quertermous T,
Megahy MS, Das Gupta DS, Griem ML.
Radiology.
1983;
148
(1):
257-8
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