Stanford School of Medicine
Cardiovascular Medicine IN THE DEPARTMENT OF MEDICINE

Department: Medicine

Division: Cardiovascular Medicine

  • Academic Appointments
    • Instructor, Medicine - Cardiovascular Medicine
    Clinical Focus
    • Endocrinology
  • Academic Appointments
    • Assistant Professor - Med Center Line, Medicine - Cardiovascular Medicine
    Clinical Focus
    • Cardiac Electrophysiology
    • Cardiology (Heart)
    • Cardiovascular Disease
  • Academic Appointments
    • Assistant Professor - Med Center Line, Medicine - Cardiovascular Medicine
    Clinical Focus
    • Cardiology
    • Cardiovascular genetics
    • Hypertrophic Cardiomyopathy
    Research Interest

    My research interests are translational. We use high dimensional genomic analysis to identify myocardial gene expression networks then use molecular, cellular and classical physiology tools to assay the biological systems. Our interests range from fit to failing hearts.

  • Academic Appointments
    • Acting Assistant Professor, Medicine - Cardiovascular Medicine
    Research Interest

    Genetic Epidemiology, Genetic Determinants of Complex Traits related to Cardiovasular Medicine, Pharmacoepidemiology of Cardiovascular Drugs & Outcomes, Biomarkers to predict major adverse cardiovascular events

  • Academic Appointments
    • Clinical Assistant Professor, Medicine - Cardiovascular Medicine
    • Lecturer, Bioengineering
    Clinical Focus
    • Cardiovascular Disease
    • Interventional Cardiology
    • Cardiovascular Medicine
  • Academic Appointments
    • Assistant Professor, Medicine - Cardiovascular Medicine
    • Member, Bio-X
    Research Interest

    My laboratory studies the mechanisms of cardiovascular development, particularly how the three major types of cardiac cells (endocardial, myocardial and epicardial cells) and neural crest cells interact with each other to generate heart tissues. We are interested in the transcriptional and signaling events that coordinate their interactions and assembly into heart tissues. The long-term goal is to understand the developmental mechanisms that control tissue formation and recapitulate the devel..

  • Academic Appointments
    • Associate Professor, Medicine - Cardiovascular Medicine
    Clinical Focus
    • Cardiology (Heart)
    • Cardiovascular Disease
    Research Interest

    Cardiac action potentials; tissue culture, voltage, clamp technique; role of calcium in ischemia arrhythmias; coronary, artery disease; myocardial infarction.

  • Academic Appointments
    • Professor, Medicine - Cardiovascular Medicine
    • Member, Bio-X
    Clinical Focus
    • Cardiology (Heart)
    • Cardiology (Heart), Preventive
    • Cardiovascular Disease
    Research Interest

    Our translational research program involves molecular, cellular, animal and human studies of endothelial biology. We are focused on the role of nitric oxide synthase (NOS) in atherosclerosis and angiogenesis. A new focus of investigation has resulted from our discovery of a novel angiogenic pathway mediated by endothelial nicotinic cholinergic receptors (nAChR). We use a wide variety of tools and approaches to investigate the role of NOS and nAChR pathways in cardiovascular biology and disease.

  • Academic Appointments
    • Acting Assistant Professor, Medicine - Cardiovascular Medicine
    Research Interest

    My research focuses on imaging cell signaling in the heart. I am developing molecular imaging probes that track to injured heart tissue, such that non-invasive imaging techniques, like cardiac MRI, can visualize these probe signals in real-time. The translational goal of my research is to develop new ways to detect early cardiac injury before permanent damage occurs, so that preventive medical therapy can be started.

  • Academic Appointments
    • Emeritus (Active) Professor, Medicine - Cardiovascular Medicine
    Clinical Focus
    • Cardiovascular Medicine
    Research Interest

    Experimental and clinical epidemiology of myocardial, infarction; exercise testing; cardiac risk factor management;, cardiac rehabilitation; systems for patient management; ischemic, heart disease; computer-based expert systems.

  • Academic Appointments
    • Consulting Assistant Professor, Medicine - Cardiovascular Medicine
  • Academic Appointments
    • Assistant Professor - Med Center Line, Medicine - Cardiovascular Medicine
    Clinical Focus
    • Cardiovascular Disease
    • Interventional Cardiology
    • Coronary Artery Disease
    Research Interest

    Dr. Fearon's general research interest is coronary physiology. In particular, he is investigating invasive methods for evaluating the coronary microcirculation. His research is currently funded by an NIH R01 Award.

  • Academic Appointments
    • Professor (Research), Medicine - Cardiovascular Medicine
  • Academic Appointments
    • Professor - Med Center Line, Medicine - Cardiovascular Medicine
    Clinical Focus
    • Cardiology (Heart)
    • Cardiovascular Medicine
    • Heart and Lung Transplantation
    Research Interest

    Adrenergic nervous system; beta-adrenergic function in, heart failure; drugs in heart failure.

  • Academic Appointments
    • Professor - Med Center Line, Medicine - Cardiovascular Medicine
    • Professor - Med Center Line (By courtesy), Orthopaedic Surgery
    • Member, Bio-X
    Clinical Focus
    • Cardiology (Heart)
    • Cardiovascular Medicine
    Research Interest

    Computerized ECG and clinical data management; exercise Physiology including expired gas analysis; the effect of chronic and acute exercise on the heart; digital recording of biological signals; diagnostic use of exercise testing; development of Expert Medical System software and educational tools.

  • Academic Appointments
    • Professor - Med Center Line, Medicine - Cardiovascular Medicine
    Clinical Focus
    • Cardiology (Heart)
    • Cardiovascular Disease
    Research Interest

    Calcium channel blockers; membrane pharmacology;, coronary physiology; antiarrhythmic drugs; cardiac hemodynamics;, cellular mechanisms of myocyte hypertrophy.

  • Academic Appointments
    • Clinical Instructor, Medicine - Cardiovascular Medicine
    Clinical Focus
    • Cardiology
    • RIght Heart Failure
    • Heart Transplantation
  • Academic Appointments
    • Emeritus Faculty, Acad Council, Medicine - Cardiovascular Medicine
  • Academic Appointments
    • Associate Professor - Med Center Line, Medicine - Cardiovascular Medicine
    • Associate Professor - Med Center Line (By courtesy), Health Research & Policy
    Research Interest

    My research interests include 1) The cost-effectiveness of new cardiovascular technologies. Example: tests to screen asymptomatic patients for left ventricular systolic dysfunction. 2) Interventions to improve the quality of care of patients with heart disease. Examples: include clinical reminders and home monitoring. 3) Outcomes research using existing clinical and administrative datasets. 4) Use of echocardiography to predict prognosis (e.g. diastolic dysfunction).

  • Academic Appointments
    • Associate Professor - Med Center Line, Medicine - Cardiovascular Medicine
    Clinical Focus
    • Cardiac Electrophysiology
    • Cardiovascular Medicine
    • Cardiovascular Disease
  • Academic Appointments
    • Professor - Med Center Line, Medicine - Cardiovascular Medicine
    Clinical Focus
    • Cardiology (Heart)
    • Cardiovascular Disease
    • Heart Transplantation
  • Academic Appointments
    • Instructor, Medicine - Cardiovascular Medicine
    Clinical Focus
    • Cardiovascular Disease
    • Cardiovascular Medicine
    Research Interest

    Dr. Khush’s clinical research interests include the evaluation of donors and recipients for heart transplantation; mechanisms of adverse outcomes after heart transplantation, including coronary allograft vasculopathy and antibody-mediated rejection; the treatment of acute decompensated heart failure; and the cardiorenal syndrome.

  • Academic Appointments
    • Assistant Professor - Med Center Line, Medicine - Cardiovascular Medicine
    Clinical Focus
    • Cardiology (Heart)
    • Cardiovascular Disease
    • Interventional Cardiology
    Research Interest

    1. Use of GP IIb/IIIa inhibitors and other pharmacotherapy in the treatment of acute myocardial infarction 2. Novel treatments and devices for the treatment of acute myocardial infarction 3. Alcohol septal ablation for hypertrophic obstructive cardiomyopathy 4. Novel approaches to coronary revascularization 5. Closure devices for atrial septal defects and patent foramen ovale

  • Academic Appointments
    • Instructor, Medicine - Cardiovascular Medicine
    Clinical Focus
    • Internal Medicine
    • Vascular Medicine
  • Academic Appointments
    • Associate Professor - Med Center Line, Medicine - Cardiovascular Medicine
    • Associate Professor - Med Center Line (By courtesy), Electrical Engineering
    Clinical Focus
    • Marfan Syndrome and Aortic Disorders
    • Cardiac Imaging
    • Echocardiography
  • Academic Appointments
    • Associate Professor - Med Center Line, Medicine - Cardiovascular Medicine
    • Associate Professor - Med Center Line (By courtesy), Molecular & Cellular Physiology
    • Associate Professor - Med Center Line (By courtesy), Electrical Engineering
    • Member, Bio-X
    Clinical Focus
    • Cardiovascular Disease
    Research Interest

    Imaging cardiovascular disease, with a focus on coronary and vascular atherosclerosis and ischemic heart disease. Projects include cellular and structural characterization of atherosclerotic plaque by MRI, optical imaging (bioluminescence and fluorescence) of vascular inflammation, as well as noninvasive coronary angiography by MRI and MRI- guided cardiovascular interventions. Additional collaborative projects include real-time cardiac MRI and multi-modality imaging of cardiac stem cell trans..

  • Academic Appointments
    • Emeritus (Active) Professor, Medicine - Cardiovascular Medicine
    • Emeritus Faculty, Acad Council, Medicine - Cardiovascular Medicine
    Research Interest

    Academic-Industrial relations; Ethics of invention.

  • Academic Appointments
    • Clinical Assistant Professor, Medicine - Cardiovascular Medicine
    Clinical Focus
    • Cardiovascular Disease
  • Academic Appointments
    • Professor, Medicine - Cardiovascular Medicine
    Research Interest

    Understanding genetic basis of cardiovascular function and disease.

  • Academic Appointments
    • Emeritus (Active) Professor, Medicine - Cardiovascular Medicine
    Clinical Focus
    • Endocrinology
    • Endocrinology / Diabetes
  • Academic Appointments
    • Professor - Med Center Line, Medicine - Cardiovascular Medicine
    • Member, Cancer Center
    Clinical Focus
    • Lymphatic Diseases
    • Cardiology (Heart)
    • Cardiology (Heart), Preventive
    Research Interest

    My clinical research includes studies on risk factor modification in atherosclerosis and coronary artery disease; clinical trials involving medical therapies for peripheral arterial insufficiency; coronary angiogenesis; therapy of lymphedema; atherand photodynamic therapy in atherosclerosis.

  • Academic Appointments
    • Professor - Med Center Line, Medicine - Cardiovascular Medicine
    Clinical Focus
    • Cardiology (Heart)
    • Cardiovascular Disease
    Research Interest

    My main research continues to be in the field of echocardiography. Several areas of research are currently being pursued.

  • Academic Appointments
    • Professor (Clinical), Medicine - Cardiovascular Medicine
    Clinical Focus
    • Cardiology (Heart)
    • Cardiovascular Disease
    • Cardiac Advanced Therapies
    Research Interest

    1. Clinical Pharmocology of Cardiovascular Drugs (a) Calcium Channel Blockers (b) Agents for Heart Failure (c) Anti-atherosclerotic Effects of Cardiovascular Drugs, e.g. Calcium Channel Blockers 2. Cardiac Transplantation/Congestive Heart Failure 3. Coronary Artery Spasm

  • Academic Appointments
    • Instructor, Medicine - Cardiovascular Medicine
    Clinical Focus
    • Aortic Disease
    • Marfan Syndrome and Aortic Disorders
    • Cardiovascular Disease
    Research Interest

    Dr. Spin began his research career studying the structural biology of low density lipoprotein, and has been augmenting his skills with intensive training in molecular biology techniques, particularly those involving high-throughput genetic expression profiling. He is especially interested in vascular smooth muscle cells, and the role of smooth muscle differentiation and phenotypic switching in development and vascular disease.

  • Academic Appointments
    • Instructor, Medicine - Cardiovascular Medicine
  • Academic Appointments
    • Emeritus Faculty-Med Ctr Line, Medicine - Cardiovascular Medicine
    Research Interest

    Coronary Angioplasty; Intramyocardial Stem cell delivery

  • Academic Appointments
    • Instructor, Medicine - Cardiovascular Medicine
    Clinical Focus
    • Cardiology (Heart)
    • Cardiovascular Disease
    • Women's Heart Health
    Research Interest

    Dr. Tremmel studies sex differences in cardiovascular disease. Current research projects include evaluating sex differences in coronary pathophysiology, young patients presenting with myocardial infarction, the impact of stress on anginal symptoms, chronic total coronary occlusions, and vascular access site complications.

  • Academic Appointments
    • Associate Professor (Research), Medicine - Cardiovascular Medicine
    • Member, Bio-X
  • Academic Appointments
    • Professor - Med Center Line, Medicine - Cardiovascular Medicine
    Clinical Focus
    • Cardiology (Heart)
    • Cardiovascular Disease
    • Heart and Lung Transplantation
    Research Interest

    I. Congestive Heart Failure New Medical Therapies Prognostic Evaluation Selection for Cardiac Transplantation II. Screening for Myocardial Necrosis New ECG Monitoring Devices New Serum Markers III. Screening for CAD Patients Who Have Received Radiation Rx Diabetics Being Considered for Renal Transplantation IV. Advanced coronary and valvular disease, evaluationg candidacy for high risk interventions.

  • Academic Appointments
    • Professor - Med Center Line, Medicine - Cardiovascular Medicine
    • Member, Cancer Center
    Clinical Focus
    • Cardiology (Heart)
    • Cardiovascular Medicine
    • Heart and Lung Transplantation
    Research Interest

    My lab is focused on understanding the mechanism mediating acute and chronic allograft failure, in particular on the role of microvascular injury in acute allograft failure and the mechanisms of mediating transplant coronary artery disease. 1. Role of microvascular injury in acute allograft failure.

  • Academic Appointments
    • Professor - Med Center Line, Medicine - Cardiovascular Medicine
    Clinical Focus
    • Cardiac Electrophysiology
    • Cardiology (Heart)
    • Cardiovascular Medicine
    Research Interest

    Dr. Wang's research centers on the development of innovative approaches to the treatment of arrhythmias, including more effective catheter ablation techniques, more reliable implantable devices, and less invasive treatments. Dr. Wang's clinical research interests include atrial fibrillation, ventricular tachycardia, syncope, and hypertrophic cardiomyopathy. Dr. Wang has active collaborations with Bioengineering, Mechanical Engineering, and Electrical Engineering Departments at Stanford.

  • Academic Appointments
    • Assistant Professor - Med Center Line, Medicine - Cardiovascular Medicine
    Clinical Focus
    • Cardiovascular Disease
    Research Interest

    1) Understanding, treating, and preventing cancer therapy-induced cardiotoxicity 2) Relationships between insulin resistance and dilated cardiomyopathy 3) Amyloidosis -- Optimizing therapy and discovering new treatments 4) Cardiorenal syndrome (clinical trials) 5) Optimization of pacemaker timing in heart failure patients 6) PET imaging of myocardial glucose metabolism

  • Academic Appointments
    • Assistant Professor - Med Center Line, Medicine - Cardiovascular Medicine
    • Assistant Professor - Med Center Line, Radiology
    • Member, Bio-X
    • Member, Cancer Center
    Clinical Focus
    • Cardiovascular Disease
    • Congenital Heart Disease (Adult)
    • Echocardiography
    Research Interest

    My lab works on biological mechanisms of adult stem cells, embryonic stem cells, and induced pluripotent stem cells. We use a combination of gene profiling, tissue engineering, physiological testing, and molecular imaging technologies to better understand stem cell biology in vitro and in vivo. For adult stem cells, we are interested in monitoring stem cell survival, proliferation, and differentiation. For ESC, we are currently studying their tumorigenicity, immunogenicity, and differentiation..

  • Academic Appointments
    • Assistant Professor - Med Center Line, Medicine - Cardiovascular Medicine
    • Member, Bio-X
    Clinical Focus
    • Cardiology (Heart)
    • Cardiovascular Medicine
    Research Interest

    Dr. Yang's research interest focuses on the comprehensive diagnosis of ischemic heart disease using cardiac MRI. Specifically, he is using novel MR imaging sequences that enable rapid and integrated imaging of the coronary arteries as well as assessment of LV function, cardiac perfusion, and myocardial viability. By combining the chemical sensitivity of nuclear magnetic resonance with high spatial and temporal resolution, a wide range of biological events spanning from molecular to physiologic ..

  • Academic Appointments
    • Professor - Med Center Line, Medicine - Cardiovascular Medicine
    Clinical Focus
    • Cardiology (Heart)
    • Cardiovascular Disease
    • Coronary Artery Disease
    Research Interest

    Coronary artery disease is the leading cause of death in men and women in the United States. Our group is interested in studying both the early and late phases of atherosclerosis so that we can better develop prevention and treatment strategies.

  • Academic Appointments
    • Professor - Med Center Line, Bioengineering
    • Professor - Med Center Line (By courtesy), Mechanical Engineering
    • Professor - Med Center Line, Medicine - Cardiovascular Medicine
    • Member, Bio-X
    Clinical Focus
    • Cardiology (Heart)
    • Cardiovascular Disease
    Research Interest

    Device development and testing in interventional, cardiology including angioplasty, atherectomy, and stents;, intravascular ultrasound: development and clinical trials; advanced, coronary imaging techniques including x-ray topography; coronary, hemodynamics especially velocity and pressure measurements

  • Academic Appointments
    • Instructor, Medicine - Cardiovascular Medicine
    Clinical Focus
    • Cardiovascular Disease
    • Cardiovascular Medicine
  • Academic Appointments
    • Clinical Assistant Professor, Medicine - Cardiovascular Medicine
    Clinical Focus
    • Cardiac Electrophysiology
    • Cardiology (Heart)
    • Cardiovascular Disease
    Research Interest

    (1) Mechanisms of Arrhythmia, including Ventricular Tachycardia, Atrial Fibrillation and other arrhythmias. (2) New technologies and devices for catheter ablation.

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