Sean M. Wu
Academic Appointments
- Assistant Professor, Medicine - Cardiovascular Medicine
- Member, Child Health Research Institute
Key Documents
Contact Information
- Academic Offices
Personal Information EmailAdministrative Contact David L.M. Preston, M.A. Program Manager, Cardiovascular Institute Email Tel Work (650) 725-7964 (office)
Professional Overview
Administrative Appointments
- Member, Child Health Research Institute (2013 - present)
- Member, American Heart Association National Research Committee, Stem Cell Research Subgroup (2013 - present)
- Member, American Heart Association National Stem Cell Therapy Writing Group (2012 - present)
- Assistant Professor of Medicine, Stanford University, School of Medicine (2012 - present)
- Organizing Committee, NIH/NHLBI Cardiovascular Regenerative Medicine Symposium (2011 - present)
- Associate Editor, BMC Cardiovascular Disease (2011 - present)
Honors and Awards
- SPARK Research Award, Division of Cardiology, Massachusetts General Hospital (2010-2011)
- Fellow, American College of Cardiology (2010)
- Progenitor Cell Biology Consortium, Co-Principal Investigator, NIH/NHLBI (2009-2016)
- NIH Director's New Innovator Award, NIH Office of the Director (2008-2013)
- Seed Grant Recipient, Harvard Stem Cell Institute (2008-2010)
- Young Investigator Competitive Award in Cardiovascular Medicine, GlaxoSmithKline Education and Research Foundation (2007-2009)
Professional Education
| Research Fellowship: | Boston Children's Hospital/Harvard Medical School, Stem Cell Biology (2006) |
| Board Certification: | Cardiovascular Medicine, ABIM (2005) |
| Fellowship: | Massachusetts General Hospital/Harvard Medical School, Cardiovascular Medicine (2004) |
| Board Certification: | Internal Medicine, ABIM (2003) |
| Residency: | Duke University Hospital, Internal Medicine (2001) |
| MD: | Duke University School of Medicine, Medicine (1999) |
Graduate & Fellowship Program Affiliations
Community and International Work
- Faculty Advisor, US
Internet Links
Scientific Focus
Current Research Interests
My lab seeks to identify mechanisms regulating cardiac lineage commitment during embryonic development and the biology of cardiac progenitor cells in development and disease. We believe that by understanding the transcriptional and epigenetic basis of cardiomyocyte growth and differentiation, we can identify the most effective ways to repair diseased adult hearts. We employ mouse and human embryonic and induced pluripotent stem cells as well as rodents as our in vivo models for investigation.
Publications
- At a crossroad: cell therapy for cardiac repair. Circ Res. 2013; (6): 884-90
- Essential and unexpected role of YY1 to promote mesodermal cardiac differentiation Circ Res. 2013: 900-910
- Of fish and mice: Clonal lineage analysis identifies divergence in myocardial development. Circ. Res.. 2013: 583-585
- Inefficient reprogramming of fibroblasts into cardiomyocytes using Gata4, Mef2c, and Tbx5. Circ Res. 2012; (1): 50-5
- Developmental and regenerative biology of multipotent cardiovascular progenitor cells. Circ Res. 2011; (3): 353-64
- Harnessing the potential of induced pluripotent stem cells for regenerative medicine. Nat Cell Biol. 2011; (5): 497-505
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