Allen Cooper

Clinical Focus

• Liver Transplantation
• Gastroenterology

Professional Education

Research Interests

The liver is the central organ in the metabolism of cholesterol and other fats. Previously my basci research laboratory studied the hepatic maetaoblism of these substances in animal and cellular models. Currently my major focus is on clinical care of patients with liver disease and I am engaged in studies of the role of NAFLD (non-alcoholic liver disease) in patients with hepatits C and in post liver transplant patients.

Publications

• Effectiveness of a screening program for hepatitis C. Cheung RC, Cunningham BA, Cooper AD. Dig Dis Sci. 2006; 51 (5): 976-81
• LDL and cAMP cooperate to regulate the functional expression of the LRP in rat ovarian granulosa cells. Azhar S, Medicherla S, Shen WJ, Fujioka Y, Fong LG, Reaven E, Cooper AD. J Lipid Res. 2006; 47 (11): 2538-50
• An apolipoprotein(a) peptide delays chylomicron remnant clearance and increases plasma remnant lipoproteins and atherosclerosis in vivo. Devlin CM, Lee SJ, Kuriakose G, Spencer C, Becker L, Grosskopf I, Ko C, Huang LS, Koschinsky ML, Cooper AD, Tabas I. Arterioscler Thromb Vasc Biol. 2005; 25 (8): 1704-10
• Removal of chylomicron remnants in transgenic mice overexpressing normal and membrane-anchored hepatic lipase. Lee SJ, Kadambi S, Yu KC, David C, Azhar S, Cooper AD, Choi SY. J Lipid Res. 2005; 46 (1): 27-35
• Apolipoprotein A-V deficiency results in marked hypertriglyceridemia attributable to decreased lipolysis of triglyceride-rich lipoproteins and removal of their remnants. Grosskopf I, Baroukh N, Lee SJ, Kamari Y, Harats D, Rubin EM, Pennacchio LA, Cooper AD. Arterioscler Thromb Vasc Biol. 2005; 25 (12): 2573-9