{"result":[{"lastName":"Chan","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurosurgery"}],"primaryAppointment":"Professor,Neurosurgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4423&type=small&showNoImage","displayName":"Pak H. Chan","firstName":"Pak","href":"http://med.stanford.edu/profiles/cvi/researcher/Pak_Chan","researchInterest":"Neuronal death after cerebral ischemia and neural injury using transgenic strategy"},{"lastName":"Giffard","clinicalFocus":[],"appointments":[{"appointment":"Professor,Anesthesia"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Anesthesia","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4657&type=small&showNoImage","displayName":"Rona Giffard","firstName":"Rona","href":"http://med.stanford.edu/profiles/cvi/researcher/Rona_Giffard","researchInterest":"The cellular and molecular basis for brain cell injury in stroke is our focus.  Astrocytes and neurons interact, and have unique vulnerabilities to injury based on their patterns of gene expression and their functional roles.  We study gene therapy with heat shock proteins, changes in mitochondrial function, oxidative stress and inflammation during ischemia. We also model cell death pathways and the effects of Hsp70."},{"lastName":"Sapolsky","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Professor,Neurosurgery"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6114&type=small&showNoImage","displayName":"Robert Sapolsky","firstName":"Robert","href":"http://med.stanford.edu/profiles/cvi/researcher/Robert_Sapolsky","researchInterest":""},{"lastName":"Taniguchi","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences"}],"primaryAppointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8680&type=small&showNoImage","displayName":"Hidetoshi Taniguchi M.D.,PhD.","firstName":"Hidetoshi","href":"http://med.stanford.edu/profiles/cvi/researcher/Hidetoshi_Taniguchi","researchInterest":"Hypoxic-ischemic brain injury in neonate\r\nThe role of prostaglandin in ischemic brain injury"},{"lastName":"Wyss-Coray","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Neurology & Neurological Sciences"}],"primaryAppointment":"Associate Professor (Research),Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3929&type=small&showNoImage","displayName":"Tony Wyss-Coray","firstName":"Tony","href":"http://med.stanford.edu/profiles/cvi/researcher/Tony_Wyss-Coray","researchInterest":"Use of genetic and molecular tools to dissect immune and inflammatory pathways in Alzheimer's and neurodegeneration."},{"lastName":"Longo","clinicalFocus":[{"focus":"Neurology"},{"focus":"Alzheimer's Disease"},{"focus":"Huntington Disease"}],"appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"}],"primaryAppointment":"Professor,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7249&type=small&showNoImage","displayName":"Frank M. Longo, M.D., Ph.D.","firstName":"Frank","href":"http://med.stanford.edu/profiles/cvi/researcher/Frank_Longo","researchInterest":"Clinical interests include Alzheimer\u0092s disease and Huntington\u0092s disease and the development of effective therapeutics for these disorders. Laboratory interests encompass the elucidation of signaling mechanisms relevant to neurodegenerative disorders and the development of novel small molecule approaches for the treatment of neurodegenerative and other neurological disorders."},{"lastName":"Murphy","clinicalFocus":[{"focus":"Psychiatry"},{"focus":"Geriatric Psychiatry"}],"appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Neurosciences"}],"primaryAppointment":"Professor,Psychiatry & Behavioral Science - Neurosciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4515&type=small&showNoImage","displayName":"Greer Murphy M.D., Ph.D.","firstName":"Greer","href":"http://med.stanford.edu/profiles/cvi/researcher/Greer_Murphy","researchInterest":"Glial cell neurotoxicity and neuroprotection in Alzheimer's disease. Genome wide expression analysis of mouse models for Alzheimer's disease. Pharmacogenetics of mood disorders and nicotine addiction."},{"lastName":"Garner","clinicalFocus":[],"appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS"},{"appointment":"Professor (By courtesy),Neurology & Neurological Sciences"}],"primaryAppointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3890&type=small&showNoImage","displayName":"Craig C. Garner","firstName":"Craig","href":"http://med.stanford.edu/profiles/cvi/researcher/Craig_Garner","researchInterest":"Our laboratory is studying synapse formation, stability and elimination at a variety of levels, e.g. from molecules to behavior.  A primary focus of the lab is to understanding the role that individual molecules play in the assembly and function of synaptic junctions.  In addition we evaluating a variety of potential treatments for cognitive impairment in Down syndrome in part by assessing the impact specific drugs on cognitive function in mouse models of Down syndrome."},{"lastName":"Steinberg","clinicalFocus":[{"focus":"Neurological Surgery"},{"focus":"Neurosurgery"},{"focus":"Neurosurgery, Pediatric"}],"appointments":[{"appointment":"Professor,Neurosurgery"},{"appointment":"Professor (By courtesy),Neurology & Neurological Sciences"}],"primaryAppointment":"Professor,Neurosurgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4646&type=small&showNoImage","displayName":"Gary Steinberg","firstName":"Gary","href":"http://med.stanford.edu/profiles/cvi/researcher/Gary_Steinberg","researchInterest":"Our laboratory investigates the pathophysiology and treatment of acute cerebral ischemia, as well as methods to restore neurologic function after stroke. Treatment strategies include mild brain hypothermia, gene transfer therapy and stem cell transplantation. Our clinical research develops innovative surgical, endovascular and radiosurgical approaches for treating patients with difficult intracranial aneurysms, complex vascular malformations and occlusive disease, including Moyamoya disease."},{"lastName":"Palmer","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Neurosurgery"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Neurosurgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5930&type=small&showNoImage","displayName":"Theo Palmer","firstName":"Theo","href":"http://med.stanford.edu/profiles/cvi/researcher/Theo_Palmer","researchInterest":"For most areas of the mammalian brain, neurogenesis concludes at birth but there are exceptions to the rule. In rodents and humans, some areas of the brain continue to make new neurons throughout life. This process is mediated by neural stem cells and our research goals are to understand how stem cell activity is regulated and whether the nascent potential of resident stem cells can be harnessed for brain repair."},{"lastName":"Sudhof","clinicalFocus":[],"appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Professor (By courtesy),Neurology & Neurological Sciences"},{"appointment":"Professor (By courtesy),Psychiatry & Behavioral Science"}],"primaryAppointment":"Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8533&type=small&showNoImage","displayName":"Thomas Sudhof","firstName":"Thomas","href":"http://med.stanford.edu/profiles/cvi/researcher/Thomas_Sudhof","researchInterest":"Information transfer at synapses mediates information processing in brain, and is impaired in many brain diseases. Thomas Südhof is interested in how synapses are formed, how presynaptic terminals release neurotransmitters at synapses, and how synapses become dysfunctional in diseases such as autism or Alzheimer's disease. To address these questions, Südhof's laboratory employs approaches ranging from biophysical studies to the electrophysiological and behavioral analyses of mutant mice."},{"lastName":"Malenka","clinicalFocus":[],"appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS"}],"primaryAppointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4670&type=small&showNoImage","displayName":"Robert Malenka","firstName":"Robert","href":"http://med.stanford.edu/profiles/cvi/researcher/Robert_Malenka","researchInterest":"Long-lasting changes in synaptic strength are important for the modification of neural circuits by experience. A major goal of my laboratory is to elucidate the molecular events that trigger various forms of synaptic plasticity and the modifications in synaptic proteins that are responsible for the changes in synaptic efficacy."},{"lastName":"de Lecea","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Psychiatry & Behavioral Science - Sleep Center"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Psychiatry & Behavioral Science - Sleep Center","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7308&type=small&showNoImage","displayName":"Luis de Lecea","firstName":"Luis","href":"http://med.stanford.edu/profiles/cvi/researcher/Luis_de Lecea","researchInterest":"Our group initially identified the hypocretins, two hypothalamic neuropeptides that have a key role in maintaining the states of vigilance. We also discovered cortistatin, a peptide that modulates cortical excitability. My lab uses molecular, pharmacological, anatomical and behavioral methods to identify new roles for these transmitters. We are also interested in the cellular and molecular mechanisms by which neuronal systems integrate homeostatic information and regulate complex behaviors."},{"lastName":"Madison","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Molecular & Cellular Physiology"}],"primaryAppointment":"Associate Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4321&type=small&showNoImage","displayName":"Daniel V. Madison","firstName":"Vernon","href":"http://med.stanford.edu/profiles/cvi/researcher/Vernon_Madison","researchInterest":"Our laboratory uses electrophysiological techniques to study the mechanisms of synaptic transmission and plasticity in the mammalian hippocampus. One of the main focuses in the lab is in the study of synaptic long-term potentiation (LTP). LTP is the persistent increase in synaptic strength that occurs after a period of heavy activity in a synaptic connection. It is the most widely studied and compelling model for mechanisms underlying memory formation in the mammalian central nervous system."},{"lastName":"Valdmanis","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pediatrics"}],"primaryAppointment":"Postdoctoral Research fellow, Pediatrics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=12455&type=small&showNoImage","displayName":"Paul Valdmanis","firstName":"Paul","href":"http://med.stanford.edu/profiles/cvi/researcher/Paul_Valdmanis","researchInterest":""},{"lastName":"Moseley","clinicalFocus":[],"appointments":[{"appointment":"Professor,Radiology - Diagnostic Radiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Radiology - Diagnostic Radiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4240&type=small&showNoImage","displayName":"Michael Moseley","firstName":"Michael","href":"http://med.stanford.edu/profiles/cvi/researcher/Michael_Moseley","researchInterest":"MR physics into tissue contrast mechanisms such as diffusion, perfusion, and functional imaging describes the research direction. Applications of cerebral stroke (brain attacks) and neurocognitive disorders are also being developed from these methods"},{"lastName":"Scott","clinicalFocus":[],"appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4165&type=small&showNoImage","displayName":"Matthew Scott","firstName":"Matthew","href":"http://med.stanford.edu/profiles/cvi/researcher/Matthew_Scott","researchInterest":"Genetic regulation of animal development and human disease. We use mice and flies to study Hedgehog/Patched signaling and its links to brain cancer, development of the neural tube and cerebellum, planar cell polarity genes, a neurodegenerative disease called Niemann-Pick syndrome that affects intracellular organelle movements, chromatin proteins in embryonic stem cells, and genetic control of body size."},{"lastName":"Nusse","clinicalFocus":[],"appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4280&type=small&showNoImage","displayName":"Roeland Nusse","firstName":"Roeland","href":"http://med.stanford.edu/profiles/cvi/researcher/Roeland_Nusse","researchInterest":"Our laboratory studies Wnt signaling in development and disease. We found recently that Wnt proteins are unusual growth factors, because they are lipid-modified. We also discovered that Wnt proteins promote the proliferation of stem cells of various origins. Current work is directed at understanding the function of the lipid on the Wnt,  using Wnt proteins as factors the expand stem cells and on understanding Wnt signaling during injury repair and regeneration."},{"lastName":"Pang","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurosciences Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Neurosciences Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9396&type=small&showNoImage","displayName":"Zhiping Pang","firstName":"Zhiping","href":"http://med.stanford.edu/profiles/cvi/researcher/Zhiping_Pang","researchInterest":""},{"lastName":"Doyle","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences"}],"primaryAppointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8914&type=small&showNoImage","displayName":"Kristian Doyle","firstName":"Kristian","href":"http://med.stanford.edu/profiles/cvi/researcher/Kristian_Doyle","researchInterest":""},{"lastName":"Gupta","clinicalFocus":[{"focus":"Dermatology"},{"focus":"Psoriasis"},{"focus":"Dermatitis, Atopic"},{"focus":"Scleroderma, Localized"},{"focus":"Lupus Erythematosus, Cutaneous"},{"focus":"Lupus Erythematosus, Discoid"},{"focus":"Dermatomyositis"}],"appointments":[{"appointment":"Instructor,Dermatology"},{"appointment":"Postdoctoral Medical fellow, Dermatology"}],"primaryAppointment":"Instructor,Dermatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8514&type=small&showNoImage","displayName":"Rajnish Gupta","firstName":"Rajnish","href":"http://med.stanford.edu/profiles/cvi/researcher/Rajnish_Gupta","researchInterest":""},{"lastName":"Ho","clinicalFocus":[{"focus":"Infectious Disease"},{"focus":"Infectious Diseases"},{"focus":"Immunocompromised Host"}],"appointments":[{"appointment":"Clinical Assistant Professor,Medicine - Infectious Diseases"}],"primaryAppointment":"Clinical Assistant Professor,Medicine - Infectious Diseases","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7106&type=small&showNoImage","displayName":"Dora Ho","firstName":"Dora","href":"http://med.stanford.edu/profiles/cvi/researcher/Dora_Ho","researchInterest":"Dr. Ho did her PhD work in HSV pathogenesis and postdoctoral research in CNS gene therapy with viral vectors.  Her current interests are in viral and fungal infections in immunocompromised patients and her research focuses on infection complications in neutropenic patients.  In collaboration with Dr. C. Dekker of the Stanford-LPCH Vaccine Program and with Dr. J. Brown of the BMT Division, she is also conducting clinical trials on vaccines, antivirals and antifungals as a co-investigator."},{"lastName":"Lu","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Pathology"}],"primaryAppointment":"Assistant Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3976&type=small&showNoImage","displayName":"Bingwei Lu","firstName":"Bingwei","href":"http://med.stanford.edu/profiles/cvi/researcher/Bingwei_Lu","researchInterest":"We are interested in understanding how neural stem cells balance their self-renewal and differentiation and how deregulation of this process can result in brain tumor. We are also interested in mechanisms of neurodegeneration in Alzheimer\u0092s and Parkinson\u0092s diseases. We are using both Drosophila and mammalian models to address these fundamental questions."},{"lastName":"Czirr","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences"}],"primaryAppointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10140&type=small&showNoImage","displayName":"Eva Czirr","firstName":"Eva","href":"http://med.stanford.edu/profiles/cvi/researcher/Eva_Czirr","researchInterest":""},{"lastName":"Lansberg","clinicalFocus":[{"focus":"Neurology"},{"focus":"Stroke"},{"focus":"Cerebrovascular Disease"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Neurology & Neurological Sciences"},{"appointment":"Assistant Professor - Med Center Line (By courtesy),Neurosurgery"}],"primaryAppointment":"Assistant Professor - Med Center Line,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5945&type=small&showNoImage","displayName":"Maarten Lansberg, M.D., Ph.D.","firstName":"Maarten","href":"http://med.stanford.edu/profiles/cvi/researcher/Maarten_Lansberg","researchInterest":"1. Imaging of Cerebral Perfusion with MRI and Xenon CT\r\n2. Determining selection criteria that identify stroke patients who are most likely to benefit from iv tPA\r\n3. Combining iv tPA with intraarterial mechanical thrombectomy for acute stroke\r\n4. Detection of Atrial Fibrillation in patients with stroke and TIA using long term ambulatory cardiac monitoring\r\n5. Prognosis of critically ill neurological patients"}]}