{"result":[{"lastName":"Stankunas","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Medicine - Cardiovascular Medicine"}],"primaryAppointment":"Instructor,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9759&type=small&showNoImage","displayName":"Kryn Stankunas","firstName":"Kryn","href":"http://med.stanford.edu/profiles/cvi/researcher/Kryn_Stankunas","researchInterest":""},{"lastName":"Shang","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, School of Medicine"}],"primaryAppointment":"Postdoctoral Research fellow, School of Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10197&type=small&showNoImage","displayName":"Ching Shang","firstName":"Ching","href":"http://med.stanford.edu/profiles/cvi/researcher/Ching_Shang","researchInterest":""},{"lastName":"Cleary","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Cancer Center"},{"appointment":"Professor,Pediatrics"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4506&type=small&showNoImage","displayName":"Michael Cleary","firstName":"Michael","href":"http://med.stanford.edu/profiles/cvi/researcher/Michael_Cleary","researchInterest":"The role of oncoproteins in cancer and development; molecular and cellular biology of hematologic malignancies; targeted molecular therapies of cancer."},{"lastName":"Crabtree","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Professor,Developmental Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4283&type=small&showNoImage","displayName":"Gerald Crabtree","firstName":"Gerald","href":"http://med.stanford.edu/profiles/cvi/researcher/Gerald_Crabtree","researchInterest":"The role of chromatin in stem cell formation and function. Development of small molecule regulators as experimental probes and therapeutic leads. Signaling through calcineurin and NFAT in vertebrate development."},{"lastName":"Graef","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Pathology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7247&type=small&showNoImage","displayName":"Isabella Graef","firstName":"Isabella","href":"http://med.stanford.edu/profiles/cvi/researcher/Isabella_Graef","researchInterest":"We are interested in addressing questions in neuronal development and function by a combination of genetic, cell biological, biochemical and chemical approaches. \r\nThe main focus of our lab is centered around two topics: 1) the interface of signaling and gene regulation in neuronal development, with a focus on calcineurin-NFAT signaling; 2) the development of small molecules, which interfere with protein-protein interactions underlying neurodegenerative diseases."},{"lastName":"Robbins","clinicalFocus":[{"focus":"Heart and Lung Transplantation"},{"focus":"Cardiothoracic Surgery"},{"focus":"Thoracic Surgery"}],"appointments":[{"appointment":"Professor,Cardiothoracic Surgery - Adult Cardiac Surgery"},{"appointment":"Professor (By courtesy),Surgery"}],"primaryAppointment":"Professor,Cardiothoracic Surgery - Adult Cardiac Surgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4247&type=small&showNoImage","displayName":"Robert C. Robbins, M. D.","firstName":"Robert","href":"http://med.stanford.edu/profiles/cvi/researcher/Robert_Robbins","researchInterest":"Stem Cell Therapy for Myocardial Restoration, Cardiopulmonary Transplantation, Cardiac Allograft Vasculopathy, Automated Anastomotic Devices, Genetics and Mechanisms of Congestive Heart Failure"},{"lastName":"Wu","clinicalFocus":[{"focus":"Cardiovascular Disease"},{"focus":"Congenital Heart Disease (Adult)"},{"focus":"Echocardiography"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Medicine - Cardiovascular Medicine"},{"appointment":"Assistant Professor - Med Center Line,Radiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Assistant Professor - Med Center Line,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6159&type=small&showNoImage","displayName":"Joseph  C. Wu","firstName":"Joseph","href":"http://med.stanford.edu/profiles/cvi/researcher/Joseph_Wu","researchInterest":"My lab works on biological mechanisms of adult stem cells, embryonic stem cells, and induced pluripotent stem cells. We use a combination of gene profiling, tissue engineering, physiological testing, and molecular imaging technologies to better understand stem cell biology in vitro and in vivo. For adult stem cells, we are interested in monitoring stem cell survival, proliferation, and differentiation. For ESC, we are currently studying their tumorigenicity, immunogenicity, and differentiation"},{"lastName":"Scott","clinicalFocus":[],"appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4165&type=small&showNoImage","displayName":"Matthew Scott","firstName":"Matthew","href":"http://med.stanford.edu/profiles/cvi/researcher/Matthew_Scott","researchInterest":"Genetic regulation of animal development and human disease. We use mice and flies to study Hedgehog/Patched signaling and its links to brain cancer, development of the neural tube and cerebellum, planar cell polarity genes, a neurodegenerative disease called Niemann-Pick syndrome that affects intracellular organelle movements, chromatin proteins in embryonic stem cells, and genetic control of body size."},{"lastName":"Monk","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9455&type=small&showNoImage","displayName":"Kelly Monk","firstName":"Kelly","href":"http://med.stanford.edu/profiles/cvi/researcher/Kelly_Monk","researchInterest":""},{"lastName":"Boxer","clinicalFocus":[{"focus":"Hematology"},{"focus":"Multiple Myeloma"},{"focus":"Multiple Myeloma - Medical Oncology"},{"focus":"Plasmacytoma"},{"focus":"Plasmacytoma - Hematology"},{"focus":"Plasmacytoma - Medical Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Hematology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Medicine - Hematology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4658&type=small&showNoImage","displayName":"Linda Boxer","firstName":"Linda","href":"http://med.stanford.edu/profiles/cvi/researcher/Linda_Boxer","researchInterest":"Regulation of expression of oncogenes in normal and malignant hematologic cells."},{"lastName":"Quertermous","clinicalFocus":[],"appointments":[{"appointment":"Professor,Medicine - Cardiovascular Medicine"}],"primaryAppointment":"Professor,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4426&type=small&showNoImage","displayName":"Thomas Quertermous, MD","firstName":"Thomas","href":"http://med.stanford.edu/profiles/cvi/researcher/Thomas_Quertermous","researchInterest":"Understanding genetic basis of cardiovascular function and disease."},{"lastName":"Weissman","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology - Stem Cell Institute"},{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor (By courtesy),Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Pathology - Stem Cell Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4605&type=small&showNoImage","displayName":"Irving Weissman","firstName":"Irving","href":"http://med.stanford.edu/profiles/cvi/researcher/Irving_Weissman","researchInterest":"Stem cell and cancer stem cell biology; development of T and B lymphocytes; cell-surface receptors for oncornaviruses in leukemia. Hematopoietic stem cells; Lymphocyte homing, lymphoma invasiveness and metastasis."},{"lastName":"Clarke","clinicalFocus":[{"focus":"Colorectal Cancer"},{"focus":"Oncology"},{"focus":"Oncology (Cancer)"}],"appointments":[{"appointment":"Professor,Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7126&type=small&showNoImage","displayName":"Michael F. Clarke, M.D.","firstName":"Michael","href":"http://med.stanford.edu/profiles/cvi/researcher/Michael_Clarke","researchInterest":"Dr. Michael F. Clarke is the Associate Director of the Stanford Institute for Stem Cell and Regenerative Medicine. In addition to his clinical duties in the division of Oncology, Dr. Clarke maintains a laboratory focused on two areas of research: i) the control of self-renewal of normal stem cells and their malignant counterparts; and ii) the identification and characterization of cancer stem cells. A central issue in stem cell biology is to understand the mechanisms that regulate self-renewa"},{"lastName":"Talbot","clinicalFocus":[],"appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4013&type=small&showNoImage","displayName":"William Talbot","firstName":"William","href":"http://med.stanford.edu/profiles/cvi/researcher/William_Talbot","researchInterest":"We use genetic and cellular approaches to investigate the molecular basis of glial development and myelination in the zebrafish. Other projects include the genetic dissection of cell fate specification in the early embryo and functional genomics in zebrafish."},{"lastName":"Nusse","clinicalFocus":[],"appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4280&type=small&showNoImage","displayName":"Roeland Nusse","firstName":"Roeland","href":"http://med.stanford.edu/profiles/cvi/researcher/Roeland_Nusse","researchInterest":"Our laboratory studies Wnt signaling in development and disease. We found recently that Wnt proteins are unusual growth factors, because they are lipid-modified. We also discovered that Wnt proteins promote the proliferation of stem cells of various origins. Current work is directed at understanding the function of the lipid on the Wnt, using Wnt proteins as factors the expand stem cells and on understanding Wnt signaling during injury repair and regeneration."},{"lastName":"Krasnow","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4120&type=small&showNoImage","displayName":"Mark Krasnow","firstName":"Mark","href":"http://med.stanford.edu/profiles/cvi/researcher/Mark_Krasnow","researchInterest":"Genetic and molecular basis of respiratory system development, maintenance, and disease in Drosophila, mouse, and human"},{"lastName":"Contag","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Pediatrics - Neonatology"},{"appointment":"Associate Professor,Microbiology & Immunology"},{"appointment":"Associate Professor (By courtesy),Radiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Pediatrics - Neonatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4036&type=small&showNoImage","displayName":"Christopher H. Contag","firstName":"Christopher","href":"http://med.stanford.edu/profiles/cvi/researcher/Christopher_Contag","researchInterest":"We develop and use the tools of molecular imaging to understand oncogenesis, reveal patterns of cell migration in immunosurveillance, monitor gene expression, visualize stem cell biology, and assess the distribution of pathogens in living animal models of human biology and disease. Biology doesn't occur in \"a vacuum\" or on coated plates--it occurs in the living body and that's were we look for biological patterns and responses to insult."},{"lastName":"Nolan","clinicalFocus":[],"appointments":[{"appointment":"Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Microbiology & Immunology - Baxter Laboratory","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4713&type=small&showNoImage","displayName":"Garry Nolan","firstName":"Garry","href":"http://med.stanford.edu/profiles/cvi/researcher/Garry_Nolan","researchInterest":"Dr. Nolan's group uses high throughput single cell analysis technology of kinase driven signaling cascades to interrogate autoimmunity, cancer, virology (influenza), bacterial pathogens (Listeria and Salmonella) as well as understanding normal immune system function. Using advanced flow cytometric techniques and computational biology approaches, we focus on high throughput drug screening, mouse models of disease in patient materials, and understanding disease processes at the single cell level."},{"lastName":"Sun","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Urology"},{"appointment":"Associate Professor,Genetics"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Urology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4402&type=small&showNoImage","displayName":"Zijie Sun","firstName":"Zijie","href":"http://med.stanford.edu/profiles/cvi/researcher/Zijie_Sun","researchInterest":"My laboratory focuses on understanding the transcriptional processes that govern the transformation of normal mammalian cells to neoplastic state."},{"lastName":"Brugmann","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Surgery"}],"primaryAppointment":"Postdoctoral Research fellow, Surgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9172&type=small&showNoImage","displayName":"Samantha Brugmann","firstName":"Samantha","href":"http://med.stanford.edu/profiles/cvi/researcher/Samantha_Brugmann","researchInterest":"Craniofacial development and patterning"},{"lastName":"Chang","clinicalFocus":[{"focus":"Dermatology"}],"appointments":[{"appointment":"Associate Professor,Dermatology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Dermatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6089&type=small&showNoImage","displayName":"Howard Y. Chang","firstName":"Howard","href":"http://med.stanford.edu/profiles/cvi/researcher/Howard_Chang","researchInterest":"The Chang group is focused on two fundamental questions in epithelial biology: (1) the basis of positional identities in epidermal structures throughout the body, and (2) how those signals and boundaries may be abrogated to allow cancer metastasis. We are investigating the roles of site-specific fibroblast differentiation in patterning the epidermis, and dissecting the mechanisms of wound healing programs in cancer metastasis."},{"lastName":"Blau","clinicalFocus":[],"appointments":[{"appointment":"Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Microbiology & Immunology - Baxter Laboratory","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4517&type=small&showNoImage","displayName":"Helen M. Blau","firstName":"Helen","href":"http://med.stanford.edu/profiles/cvi/researcher/Helen_Blau","researchInterest":"Molecular and cellular mechanisms that control muscle and neuronal growth; stem cell biology, differentiation, and tumorigenicity. Regulating stem cell fate in vitro and in vivo. Stem cell therapies. Hematopoietic and muscle stem cells. Characterizing and bioengineering stem cell niches. Nuclear reprogramming. Muscle development and disease. Drug delivery. Tracking cell behavior in vitro and in vivo. Understanding tissue degeneration and regeneration."},{"lastName":"Rabinovitch","clinicalFocus":[{"focus":"Cardiology (Heart), Pediatric"},{"focus":"Pediatric Cardiology"}],"appointments":[{"appointment":"Professor,Pediatrics - Cardiology"},{"appointment":"Professor (By courtesy),Developmental Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Pediatrics - Cardiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3897&type=small&showNoImage","displayName":"Marlene Rabinovitch","firstName":"Marlene","href":"http://med.stanford.edu/profiles/cvi/researcher/Marlene_Rabinovitch","researchInterest":"Our research focuses on understanding the regulation of genes associated with cardiovascular development and disease, through the use of cultured cells and tissues and genetically modified mouse models. A variety of different aberrant pathways are being characterized, including those related to signaling through the bone morphogenetic proteins, serotonin and the S100 family of calcium binding proteins, and those defining how a microtubule associated protein regulates mRNA translation."},{"lastName":"Helms","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Surgery - Plastic/Recon Surgery"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Surgery - Plastic/Recon Surgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6152&type=small&showNoImage","displayName":"Jill Helms","firstName":"Jill","href":"http://med.stanford.edu/profiles/cvi/researcher/Jill_Helms","researchInterest":"Dr. Helms' research interests center around craniofacial development and regenerative medicine."},{"lastName":"Beygui","clinicalFocus":[{"focus":"Heart and Lung Transplantation"},{"focus":"Valvular Heart Diseases"},{"focus":"Adult Cardiac Surgery"},{"focus":"Coronary Artery Bypass"},{"focus":"Aortic Aneurysm"},{"focus":"Arrhythmias, Cardiac"},{"focus":"Thoracic Surgery"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Cardiothoracic Surgery"},{"appointment":"Associate Professor - Med Center Line,Surgery"}],"primaryAppointment":"Associate Professor - Med Center Line,Cardiothoracic Surgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8415&type=small&showNoImage","displayName":"Ramin E. Beygui, M.D.","firstName":"Ramin","href":"http://med.stanford.edu/profiles/cvi/researcher/Ramin_Beygui","researchInterest":""}]}