{"result":[{"lastName":"Weiss","clinicalFocus":[{"focus":"Emergency Medicine"},{"focus":"Infectious Diseases"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Surgery"},{"appointment":"Clinical Associate Professor,Surgery - Emergency Medicine"}],"primaryAppointment":"Assistant Professor - Med Center Line,Surgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4654&type=small&showNoImage","displayName":"Eric L Weiss, MD, DTM&H","firstName":"Eric Leonard","href":"http://med.stanford.edu/profiles/cvi/researcher/Eric Leonard_Weiss","researchInterest":"Ignorance of Hepatitis A Among Travelers (writing up data).Travelers Neglecting to Seek Pre Travel Medicine Advice (writing up data).Fluoroquinolones in the Treatment of Complicated Urinary Tract Infections (new ED study)"},{"lastName":"Prince","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"}],"primaryAppointment":"Professor,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4531&type=small&showNoImage","displayName":"David Prince","firstName":"David","href":"http://med.stanford.edu/profiles/cvi/researcher/David_Prince","researchInterest":"Experiments examine \r\n1)intrinsic properties of neuronal membranes; actions of neurotransmitters that regulate neocortical and thalamic excitability\r\n2) chronic epileptogenesis following cortical injury; changes in intracortical connectivity and receptors; \r\n3) effects of early injury and activity on cortical development/maldevelopment Electrophysiological, anatomical and pharmacological techniques employed.\r\n4. prophylaxis of postraumatic epilepsy\r\n5. Neocortical interneuronal function/modulation"},{"lastName":"Huguenard","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Professor (By courtesy),Molecular & Cellular Physiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4124&type=small&showNoImage","displayName":"John Huguenard","firstName":"John","href":"http://med.stanford.edu/profiles/cvi/researcher/John_Huguenard","researchInterest":"We are interested in the neuronal mechanisms that underlie synchronous oscillatory activity in the thalamus, cortex and the massively interconnected thalamocortical system. Such oscillations are related to cognitive processes, normal sleep activities and certain forms of epilepsy. Our approach is an analysis of the discrete components (cells, synapses, microcircuits) that make up thalamic and cortical circuits, and reconstitution of components into in silico computational networks."},{"lastName":"Tsien","clinicalFocus":[],"appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"}],"primaryAppointment":"Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4189&type=small&showNoImage","displayName":"Richard Tsien","firstName":"Richard","href":"http://med.stanford.edu/profiles/cvi/researcher/Richard_Tsien","researchInterest":"We study synaptic communication between brain cells with the goal of understanding neuronal computations and memory mechanisms. Main areas of focus include: presynaptic calcium channels, mechanisms of vesicular fusion and recycling. Modulation of synaptic strength through changes in postsynaptic receptors and dendritic morphology. Signaling that links synaptic activity to nuclear transcription and local protein translation. Techniques include imaging, electrophysiology, molecular biology."},{"lastName":"Tan","clinicalFocus":[{"focus":"Kidney and Pancreas Transplantation"},{"focus":"Nephrology"},{"focus":"Nephrology (Kidney)"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Medicine - Nephrology"}],"primaryAppointment":"Assistant Professor - Med Center Line,Medicine - Nephrology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3846&type=small&showNoImage","displayName":"Jane C. Tan","firstName":"Jane","href":"http://med.stanford.edu/profiles/cvi/researcher/Jane_Tan","researchInterest":"My research relates to issues pertaining to clinical kidney transplantation. We have ongoing studies on the following topics.\r\n1. Renal senescence and kidney transplant, and chronic allograft nephropathy.\r\n2. Living donor safety and response to uninephrectomy.\r\n3. Biomarkers for post-transplant monitoring."},{"lastName":"Gardner","clinicalFocus":[{"focus":"Clinical Pharmacology"}],"appointments":[{"appointment":"Professor,Medicine - Clinical Pharmacology"}],"primaryAppointment":"Professor,Medicine - Clinical Pharmacology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4500&type=small&showNoImage","displayName":"Phyllis Gardner","firstName":"Phyllis","href":"http://med.stanford.edu/profiles/cvi/researcher/Phyllis_Gardner","researchInterest":"Ion channels and signal transduction;  patch clamp and fluorometric analysis; cell and molecular biology; cystic fibrosis gene therapy."},{"lastName":"Bertaccini","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor - Med Center Line,Anesthesia"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor - Med Center Line,Anesthesia","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4079&type=small&showNoImage","displayName":"Edward Bertaccini","firstName":"Edward","href":"http://med.stanford.edu/profiles/cvi/researcher/Edward_Bertaccini","researchInterest":"molecular modeling of anesthetic-protein interactions, molecular modeling of the ligand-gated ion channels"},{"lastName":"Maduke","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Molecular & Cellular Physiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3812&type=small&showNoImage","displayName":"Merritt Maduke","firstName":"Merritt","href":"http://med.stanford.edu/profiles/cvi/researcher/Merritt_Maduke","researchInterest":"Molecular mechanisms of chloride channels & transporters studied by integration of structural and electrophysiological methods."},{"lastName":"Fisher","clinicalFocus":[{"focus":"Epilepsy"},{"focus":"Neurology"},{"focus":"EEG"},{"focus":"Consciousness, Loss of"},{"focus":"Convulsion, Non-Epileptic"},{"focus":"Epilepsy, Complex Partial"},{"focus":"Epilepsy, Generalized"},{"focus":"Epilepsy, Temporal Lobe"},{"focus":"Epilepsy, Tonic-Clonic"}],"appointments":[{"appointment":"Professor - Med Center Line,Neurology & Neurological Sciences"},{"appointment":"Professor - Med Center Line (By courtesy),Neurosurgery"}],"primaryAppointment":"Professor - Med Center Line,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4638&type=small&showNoImage","displayName":"Robert Fisher","firstName":"Robert","href":"http://med.stanford.edu/profiles/cvi/researcher/Robert_Fisher","researchInterest":"Dr. Fisher is interested in clincal, laboratory and translational aspects of epilepsy research.  Prior work has included: electrical deep brain stimulation for epilepsy, studied in laboratory models and clinical trials; drug delivery to a seizure focus; mechanisms of absence epilepsy studied with in vitro slices of brain thalamus; hyperthermic seizures; diagnosis and treatment of non-epileptic seizures, the post-ictal state; driving and epilepsy; new antiepileptic drugs; surgery for epilepsy."},{"lastName":"Sohal","clinicalFocus":[{"focus":"Psychiatry"}],"appointments":[{"appointment":"Instructor,Psychiatry & Behavioral Science - Psychopharmacology"}],"primaryAppointment":"Instructor,Psychiatry & Behavioral Science - Psychopharmacology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10396&type=small&showNoImage","displayName":"Vikaas Sohal","firstName":"Vikaas","href":"http://med.stanford.edu/profiles/cvi/researcher/Vikaas_Sohal","researchInterest":""},{"lastName":"Garner","clinicalFocus":[],"appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS"},{"appointment":"Professor (By courtesy),Neurology & Neurological Sciences"}],"primaryAppointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3890&type=small&showNoImage","displayName":"Craig C. Garner","firstName":"Craig","href":"http://med.stanford.edu/profiles/cvi/researcher/Craig_Garner","researchInterest":"Our laboratory is studying synapse formation, stability and elimination at a variety of levels, e.g. from molecules to behavior.  A primary focus of the lab is to understanding the role that individual molecules play in the assembly and function of synaptic junctions.  In addition we evaluating a variety of potential treatments for cognitive impairment in Down syndrome in part by assessing the impact specific drugs on cognitive function in mouse models of Down syndrome."},{"lastName":"Dolmetsch","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Neurobiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Neurobiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4040&type=small&showNoImage","displayName":"Ricardo Dolmetsch","firstName":"Ricardo","href":"http://med.stanford.edu/profiles/cvi/researcher/Ricardo_Dolmetsch","researchInterest":"Our lab studies the underlying neurobiology of autism and other neuro-developmental disorders.  We are particularly interested in understanding how electrical activity and calcium signals control the development of the brain and how this is altered in children with autism spectrum disorders. We are also developing new tools to study and repair the developing brain."},{"lastName":"Lewis","clinicalFocus":[],"appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4176&type=small&showNoImage","displayName":"Richard Lewis","firstName":"Richard","href":"http://med.stanford.edu/profiles/cvi/researcher/Richard_Lewis","researchInterest":"We study molecular mechanisms of calcium signaling with a focus on store-operated CRAC channels and their essential roles in T cell development and function.  Currently we aim to define the molecular mechanism for CRAC channel activation and the means by which calcium signal dynamics mediate specific activation of transcription factors and T-cell genes during development."},{"lastName":"Sudhof","clinicalFocus":[],"appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Professor (By courtesy),Neurology & Neurological Sciences"},{"appointment":"Professor (By courtesy),Psychiatry & Behavioral Science"}],"primaryAppointment":"Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8533&type=small&showNoImage","displayName":"Thomas Sudhof","firstName":"Thomas","href":"http://med.stanford.edu/profiles/cvi/researcher/Thomas_Sudhof","researchInterest":"Information transfer at synapses mediates information processing in brain, and is impaired in many brain diseases. Thomas Südhof is interested in how synapses are formed, how presynaptic terminals release neurotransmitters at synapses, and how synapses become dysfunctional in diseases such as autism or Alzheimer's disease. To address these questions, Südhof's laboratory employs approaches ranging from biophysical studies to the electrophysiological and behavioral analyses of mutant mice."},{"lastName":"Schmiesing","clinicalFocus":[{"focus":"Anesthesia"},{"focus":"Peoperative Assessment, Anesthesia, Information technology,"}],"appointments":[{"appointment":"Clinical Associate Professor,Anesthesia"}],"primaryAppointment":"Clinical Associate Professor,Anesthesia","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4666&type=small&showNoImage","displayName":"Cliff Schmiesing, MD","firstName":"Clifford","href":"http://med.stanford.edu/profiles/cvi/researcher/Clifford_Schmiesing","researchInterest":""},{"lastName":"Pang","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurosciences Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Neurosciences Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9396&type=small&showNoImage","displayName":"Zhiping Pang","firstName":"Zhiping","href":"http://med.stanford.edu/profiles/cvi/researcher/Zhiping_Pang","researchInterest":""},{"lastName":"Weissman","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology - Stem Cell Institute"},{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor (By courtesy),Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Pathology - Stem Cell Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4605&type=small&showNoImage","displayName":"Irving Weissman","firstName":"Irving","href":"http://med.stanford.edu/profiles/cvi/researcher/Irving_Weissman","researchInterest":"Stem cell and cancer stem cell biology; development of T and B lymphocytes; cell-surface receptors for oncornaviruses in leukemia. Hematopoietic stem cells; Lymphocyte homing, lymphoma invasiveness and metastasis."},{"lastName":"Trudell","clinicalFocus":[],"appointments":[{"appointment":"Professor,Anesthesia"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Anesthesia","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4617&type=small&showNoImage","displayName":"James Trudell","firstName":"James","href":"http://med.stanford.edu/profiles/cvi/researcher/James_Trudell","researchInterest":"Molecular theories of anesthesia. My emphasis is on the molecular interactions of inhalational anesthetics and alcohol. I perform computational chemistry simulations on how these molecules bind to putative receptor sites. I am also interested in modeling receptor proteins in which chimeras cause loss or enhancement of anesthetic sensitivity."},{"lastName":"Stryer","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Neurobiology"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Neurobiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3795&type=small&showNoImage","displayName":"Lubert Stryer","firstName":"Lubert","href":"http://med.stanford.edu/profiles/cvi/researcher/Lubert_Stryer","researchInterest":""},{"lastName":"Thompson","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6245&type=small&showNoImage","displayName":"Stuart Thompson","firstName":"Stuart","href":"http://med.stanford.edu/profiles/cvi/researcher/Stuart_Thompson","researchInterest":""},{"lastName":"Deisseroth","clinicalFocus":[{"focus":"Psychiatry"}],"appointments":[{"appointment":"Assistant Professor,Bioengineering"},{"appointment":"Associate Professor,Bioengineering"},{"appointment":"Associate Professor,Psychiatry & Behavioral Science"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Bioengineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6080&type=small&showNoImage","displayName":"Karl Deisseroth","firstName":"Karl","href":"http://med.stanford.edu/profiles/cvi/researcher/Karl_Deisseroth","researchInterest":"Research in Dr. Deisseroth's laboratory focuses on developing optical, molecular and cellular tools to observe, perturb, and re-engineer brain circuits. His laboratory is based in the James H. Clark Center at Stanford and has developed optogenetic and tissue engineering methods, employing techniques spanning electrophysiology, molecular biology, optics, neural activity imaging, animal behavior, and computational neural network modeling."},{"lastName":"Clarke","clinicalFocus":[{"focus":"Colorectal Cancer"},{"focus":"Oncology"},{"focus":"Oncology (Cancer)"}],"appointments":[{"appointment":"Professor,Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7126&type=small&showNoImage","displayName":"Michael F. Clarke, M.D.","firstName":"Michael","href":"http://med.stanford.edu/profiles/cvi/researcher/Michael_Clarke","researchInterest":"Dr. Michael F. Clarke is the Associate Director of the Stanford Institute for Stem Cell and Regenerative Medicine.  In addition to his clinical duties in the division of Oncology, Dr. Clarke maintains a laboratory  focused on two areas of research: i) the control of self-renewal of normal stem cells and their malignant counterparts; and ii) the identification and characterization of cancer stem cells. A central issue in stem cell biology is to understand the mechanisms that regulate self-renewa"},{"lastName":"Roth","clinicalFocus":[],"appointments":[{"appointment":"Emeritus (Active) Professor,Chemical and Systems Biology"}],"primaryAppointment":"Emeritus (Active) Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4175&type=small&showNoImage","displayName":"Richard Roth","firstName":"Richard","href":"http://med.stanford.edu/profiles/cvi/researcher/Richard_Roth","researchInterest":"Insulin is one of the primary regulators of rapid anabolic responses in the body. Defects in the synthesis and/or ability of cells to respond to insulin results in the condition known as diabetes mellitus. To better design methods of treatment for this disorder, we have been focusing our research on how insulin elicits its various biological responses."},{"lastName":"Nolan","clinicalFocus":[],"appointments":[{"appointment":"Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Microbiology & Immunology - Baxter Laboratory","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4713&type=small&showNoImage","displayName":"Garry Nolan","firstName":"Garry","href":"http://med.stanford.edu/profiles/cvi/researcher/Garry_Nolan","researchInterest":"Dr. Nolan's group uses high throughput single cell analysis technology of kinase driven signaling cascades to interrogate autoimmunity, cancer, virology (influenza), bacterial pathogens (Listeria and Salmonella) as well as understanding normal immune system function.  Using advanced flow cytometric techniques and computational biology approaches, we focus on high throughput drug screening, mouse models of disease in patient materials, and understanding disease processes at the single cell level."},{"lastName":"Mochly-Rosen","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4256&type=small&showNoImage","displayName":"Daria Mochly-Rosen","firstName":"Daria","href":"http://med.stanford.edu/profiles/cvi/researcher/Daria_Mochly-Rosen","researchInterest":"We are studying the mechanism of protein kinase C-mediated signal transduction in several disease models. Based on our recent data, we proposed a working hypothesis that activated PKC isozymes bind to intracellular receptor proteins located at different subcellular sites, and that these receptors differentially bind specific PKC isozymes."}]}