Clifford Chin

Publication Details

• [Formula: see text]@RER (1.0): A Novel Submaximal Cardiopulmonary Exercise Index.

  Chin C, Kazmucha J, Kim N, Suryani R, Olson I. Pediatr Cardiol. 2009

  Maximal oxygen consumption ([Formula: see text]) is the "gold standard" by which to assess functional capacity; however, it is effort dependent. [Formula: see text]@RER(1.0) is defined when [Formula: see text]. Between December 22, 1997 and November 9, 2004, 305 pediatric subjects underwent cycle ergometer cardiopulmonary exercise testing, exercised to exhaustion, and reached a peak respiratory exchange ratio >/=1.10. Group 1 subjects achieved a peak [Formula: see text] of predicted [Formula: see text]; group 2 subjects achieved a peak [Formula: see text] of predicted [Formula: see text]; and group 3 subjects achieved a peak [Formula: see text] between 61 and 79% of predicted [Formula: see text]. Linear regression analysis was performed for [Formula: see text]@RER(1.0) as a function of predicted [Formula: see text] for group 1 subjects. A -2 SD regression line and equation was created. [Formula: see text]@RER(1.0) data from groups 2 and 3 were plotted onto the normative graph. Contingency table and relative-risk analysis showed that an abnormal [Formula: see text]@RER(1.0) predicted an abnormal peak [Formula: see text](positive-predictive value 83%, negative-predictive value 85%, sensitivity 84%, and specificity 84%). [Formula: see text]@RER(1.0) is a highly sensitive, specific, and predictive submaximal index of functional capacity. This submaximal index is easy to identify without subjectivity. This index may aid in the evaluation of subjects who cannot exercise to maximal parameters.

  PubMedID: 19812880