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Ruth O'HaraAcademic Appointments
Appointment
Organization
Associate Professor (Research)
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NIH Biosketch DocResearch Interests
Dr. O’Hara’s research aims to identify the physiological markers of neurocognitive impairment in a broad range of late-life disorders, including Mild Cognitive Impairment, Alzheimer’s disease (AD), Late-Life Depression, and Late-Life Anxiety disorders. Using neuroimaging and genetic approaches to investigating the impact of psychological and physiological stress, and more recently sleep disorders, her research aims to: (1) more fully characterize the genetic risk factors and physiological mechanisms underlying normal and pathological cognitive impairment; (2) assist with early identification of those at greatest risk for cognitive decline, and dementia; (3) increase our understanding of the role of cognitive impairment in exacerbating late-life psychiatric disorders; and (4) develop interventions aimed at reducing this impairment.
Publications
- O'hara R, Sommer B, Way N, Kraemer HC, Taylor J, Murphy G "Slower speed-of-processing of cognitive tasks is associated with presence of the apolipoprotein epsilon4 allele." J Psychiatr Res 2007; More »
- O'hara R, Schröder CM, Mahadevan R, Schatzberg AF, Lindley S, Fox S, Weiner M, Kraemer HC, Noda A, Lin X, Gray HL, Hallmayer JF "Serotonin transporter polymorphism, memory and hippocampal volume in the elderly: association and interaction with cortisol." Mol Psychiatry 2007; More »
- O'hara R, Schröder C "Unraveling the relationship of obstructive sleep-disordered breathing to major depressive disorder." Sleep Med 2006; More »
- O'hara R, "Stress, aging, and mental health." Am J Geriatr Psychiatry 2006; 14: 4: 295-8 More »
- O'hara R, Miller E, Liao CP, Way N, Lin X, Hallmayer J "COMT genotype, gender and cognition in community-dwelling, older adults." Neurosci Lett 2006; More »
41 publications: view full list
