Stanford School of Medicine
Cardiovascular Institute–

Ching-Pin Chang

Email:
Phone:(650) 736-4108
Profile: http://med.stanford.edu/profiles/Ching-Pin_Chang/
Academic Appointments
Appointment
Organization
Assistant Professor
Medicine - Cardiovascular Medicine
Member
Bio-X
Graduate & Fellowship Program Affiliations
Cancer Biology ; Medicine ;
 
Honors & Awards
Title
Organization
Date(s)
March of Dimes Research Program Award
March of Dimes Foundation
2007
Medical Grant Award
Children's Heart Foundation
2007
Faculty Scholar Award
Donald E. and Delia B. Baxter Foundation
2006
National Scientist Development Award
American Heart Association
2005
Research Incentive Award
Office of Technology and Licensing, Stanford University
2005
8  honors and awards: view full list
Professional Education
Degree
Awarding Institution
Field of Study
Year of Graduation
Physician-Scientist Fellowship
Howard Hughes Medical Institute
Cardiovascular Development
2004
Cardiology Fellowship
Stanford University Medical Center
Clinical Cardiology
2001
Residency
Massachusetts General Hospital, Harvard
Internal Medicine
1999
Ph.D.
Stanford University
Cancer Biology
1997
M.D.
National Taiwan University
Medicine
-
Web Site Links
Research/Lab website:   http://cvmedicine.stanford.edu/research/chang_lab.html
Research Interests

My laboratory studies the mechanisms of cardiovascular development, particularly how the three major types of cardiac cells (endocardial, myocardial and epicardial cells) and neural crest cells interact with each other to generate heart tissues. We are interested in the transcriptional and signaling events that coordinate their interactions and assembly into heart tissues. The long-term goal is to understand the developmental mechanisms that control tissue formation and recapitulate the developmental processes for therapeutic or regenerative purposes. Furthermore, we have generated mouse models of cardiomyopathy and models that allow us to study the repair mechanisms of vascular injury in adult. We aim to applying lessons learned from our developmental studies to investigating the mechanisms of adult disease.

Publications
  • Stankunas K, Hang CT, Tsun ZY, Chen H, Lee NV, Wu JI, Shang C, Bayle JH, Shou W, Iruela-Arispe ML, Chang CP "Endocardial Brg1 Represses ADAMTS1 to Maintain the Microenvironment for Myocardial Morphogenesis." Dev Cell 2008; 14: 2: 298-311 More »
  • Arron JR, Winslow MM, Polleri A, Chang CP, Wu H, Gao X, Neilson JR, Chen L, Heit JJ, Kim SK, Yamasaki N, Miyakawa T, Francke U, Graef IA, Crabtree GR "NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21." Nature 2006; 441: 7093: 595-600 More »
  • Chang CP, Neilson JR, Bayle JH, Gestwicki JE, Kuo A, Stankunas K, Graef IA, Crabtree GR "A field of myocardial-endocardial NFAT signaling underlies heart valve morphogenesis." Cell 2004; 118: 5: 649-63 More »
  • Piper DE, Batchelor AH, Chang CP, Cleary ML, Wolberger C "Structure of a HoxB1-Pbx1 heterodimer bound to DNA: role of the hexapeptide and a fourth homeodomain helix in complex formation." Cell 1999; 96: 4: 587-97 More »
  • Chang CP, Jacobs Y, Nakamura T, Jenkins NA, Copeland NG, Cleary ML "Meis proteins are major in vivo DNA binding partners for wild-type but not chimeric Pbx proteins." Mol Cell Biol 1997; 17: 10: 5679-87 More »
20 publications:   view full list

Footer Links: