Ramin E. Beygui, M.D.
Publication Details
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Protein-polymer hybrid nanoparticles for drug delivery.
Small. 2012; (23): 3573-8
Amphiphilic bovine serum albumin-poly(methyl methacrylate) conjugate forms nanoparticles with the uniform size of ~100 nm by self-assembling. Loaded with the hydrophobic anti-tumor drug camptothecin, the nanoparticle efficiently delivers drugs into cancer cells, and thus inhibits ~79% of tumor growth in animals compared with free drug.
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