{"result":[{"lastName":"Shatz","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Professor,Neurobiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8146&type=small&showNoImage","displayName":"Carla Shatz","firstName":"Carla","href":"http://med.stanford.edu/profiles/Carla_Shatz","researchInterest":"The goal of research in the Shatz Laboratory is to discover how brain circuits are tuned up by experience during critical periods of development both before and after birth by elucidating cellular and molecular mechanisms that transform early fetal and neonatal brain circuits into mature connections. To discover mechanistic underpinnings of circuit tuning, the lab has conducted functional screens for genes regulated by neural activity and studied their function for vision, learning and memory."},{"lastName":"Prince","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4531&type=small&showNoImage","displayName":"David Prince","firstName":"David","href":"http://med.stanford.edu/profiles/David_Prince","researchInterest":"Experiments examine \r\n1)intrinsic properties of neuronal membranes; actions of neurotransmitters that regulate neocortical and thalamic excitability\r\n2) chronic epileptogenesis following cortical injury; changes in intracortical connectivity and receptors; \r\n3) effects of early injury and activity on cortical development/maldevelopment Electrophysiological, anatomical and pharmacological techniques employed.\r\n4. prophylaxis of postraumatic epilepsy\r\n5. Neocortical interneuronal function/modulation"},{"lastName":"Hestrin","clinicalFocus":[],"appointments":[{"appointment":"Professor,Comparative Medicine"}],"primaryAppointment":"Professor,Comparative Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4343&type=small&showNoImage","displayName":"Shaul Hestrin","firstName":"Shaul","href":"http://med.stanford.edu/profiles/Shaul_Hestrin","researchInterest":"The main interest of my lab is to understand how the properties of neocortical neurons and the circuits they form give rise to cortical activity and function. Our approach includes recordings from multiple cells, calcium imaging, two-photon imaging and viral-based optogenetic methods to activate  cortical neurons as well as cortical afferents."},{"lastName":"Paz","clinicalFocus":[],"appointments":[{"appointment":"Basic Life Science Research Associate,Neurology & Neurological Sciences"}],"primaryAppointment":"Basic Life Science Research Associate,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10164&type=small&showNoImage","displayName":"Jeanne T. Paz","firstName":"Jeanne","href":"http://med.stanford.edu/profiles/Jeanne_Paz","researchInterest":""},{"lastName":"Christian","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences"}],"primaryAppointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8800&type=small&showNoImage","displayName":"Catherine Christian","firstName":"Catherine","href":"http://med.stanford.edu/profiles/Catherine_Christian","researchInterest":""},{"lastName":"Ryu","clinicalFocus":[{"focus":"Neurological Surgery"}],"appointments":[{"appointment":"Consulting Professor,Electrical Engineering - Integrated Circuits Laboratory Operations"}],"primaryAppointment":"Consulting Professor,Electrical Engineering - Integrated Circuits Laboratory Operations","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7564&type=small&showNoImage","displayName":"Stephen Ryu, MD","firstName":"Stephen","href":"http://med.stanford.edu/profiles/Stephen_Ryu","researchInterest":"Clinical research involves minimally invasive spine surgery techniques and outcomes. Also interested in spine radiosurgery. Scientific research involved brain-machine interface research with the application of neural motor prosthetic systems."},{"lastName":"Wandell","clinicalFocus":[],"appointments":[{"appointment":"Professor,Social Sciences Cluster - Psychology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Professor,Social Sciences Cluster - Psychology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7651&type=small&showNoImage","displayName":"Brian A. Wandell","firstName":"Brian","href":"http://med.stanford.edu/profiles/Brian_Wandell","researchInterest":"The development and organization of visual cortex.  The study of the brain pathways essential for reading development.  Diffusion tensor imaging, functional magnetic resonance imaging and computational modeling of visual perception and brain processes."},{"lastName":"Barres","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurobiology"},{"appointment":"Member,Bio-X"},{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor,Neurology & Neurological Sciences"}],"primaryAppointment":"Professor,Neurobiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4239&type=small&showNoImage","displayName":"Ben Barres","firstName":"Ben","href":"http://med.stanford.edu/profiles/Ben_Barres","researchInterest":"Our lab is interested in the neuronal-glial interactions that underlie the development and function of the mammlian central nervous system."},{"lastName":"Kendig","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Anesthesia"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Anesthesia","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4161&type=small&showNoImage","displayName":"Joan Kendig","firstName":"Joan","href":"http://med.stanford.edu/profiles/Joan_Kendig","researchInterest":"My laboratory tries to find out how pharmacologic agents used in the practice of anesthesia (general anesthetic and analgesic agents) lead to therapeutically desireable endpoints including unconsciousness, immobility and absence of pain. The old idea that general anesthetics are uniformly non-specific \"membrane stabilizers\" is giving way to a new realization that these agents exert specific actions on particular ion channels and intracellular signalling systems."},{"lastName":"Huguenard","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Professor (By courtesy),Molecular & Cellular Physiology"}],"primaryAppointment":"Professor,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4124&type=small&showNoImage","displayName":"John Huguenard","firstName":"John","href":"http://med.stanford.edu/profiles/John_Huguenard","researchInterest":"We are interested in the neuronal mechanisms that underlie synchronous oscillatory activity in the thalamus, cortex and the massively interconnected thalamocortical system. Such oscillations are related to cognitive processes, normal sleep activities and certain forms of epilepsy. Our approach is an analysis of the discrete components (cells, synapses, microcircuits) that make up thalamic and cortical circuits, and reconstitution of components into in silico computational networks."},{"lastName":"MacIver","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Anesthesia"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor (Research),Anesthesia","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4009&type=small&showNoImage","displayName":"M Bruce MacIver","firstName":"M","href":"http://med.stanford.edu/profiles/M_MacIver","researchInterest":"We study drug effects on the nervous system. Cellular, synaptic and molecular drug actions are investigated using electrophysiological and pharmacological tools in cortical/hippocampal brain slice preparations. We are also interested in mechanisms of neuronal integration and synchronization, especially related to patterns of EEG activity seen in vivo and in brain slices."},{"lastName":"Boahen","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Bioengineering"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Bioengineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7204&type=small&showNoImage","displayName":"Kwabena Boahen","firstName":"Kwabena","href":"http://med.stanford.edu/profiles/Kwabena_Boahen","researchInterest":""},{"lastName":"Baccus","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Neurobiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Neurobiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6027&type=small&showNoImage","displayName":"Stephen A. Baccus","firstName":"Stephen","href":"http://med.stanford.edu/profiles/Stephen_Baccus","researchInterest":"We study how the neural circuitry of the vertebrate retina encodes visual information and performs computations. To control and measure the retinal circuit, we present visual images while performing simultaneous two-photon imaging and multielectrode recording. We perturb the circuit as it operates using simultaneous intracellular current injection and multielectrode recording, and use the resulting large data sets to construct models of retinal computation."},{"lastName":"Garner","clinicalFocus":[],"appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS"},{"appointment":"Member,Bio-X"},{"appointment":"Professor (By courtesy),Neurology & Neurological Sciences"}],"primaryAppointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3890&type=small&showNoImage","displayName":"Craig C. Garner","firstName":"Craig","href":"http://med.stanford.edu/profiles/Craig_Garner","researchInterest":"Our laboratory is studying synapse formation, stability and elimination at a variety of levels, e.g. from molecules to behavior.  A primary focus of the lab is to understanding the role that individual molecules play in the assembly and function of synaptic junctions.  In addition we evaluating a variety of potential treatments for cognitive impairment in Down syndrome in part by assessing the impact specific drugs on cognitive function in mouse models of Down syndrome."},{"lastName":"Kerchner","clinicalFocus":[{"focus":"Alzheimer's Disease"},{"focus":"Mild Cognitive Impairment"},{"focus":"Dementia"},{"focus":"Behavioral Neurology"},{"focus":"Neurodegenerative Disease"},{"focus":"Neuropsychology"},{"focus":"Neurology"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Neurology & Neurological Sciences"}],"primaryAppointment":"Assistant Professor - Med Center Line,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=15338&type=small&showNoImage","displayName":"Geoffrey Kerchner","firstName":"Geoffrey","href":"http://med.stanford.edu/profiles/Geoffrey_Kerchner","researchInterest":"Dr. Kerchner is a behavioral neurologist who cares for patients with Alzheimer's disease and other age-related neurodegenerative illnesses. He studies the use of ultra-high field MRI and other advanced neuroimaging technologies to reveal how these diseases affect the microscopic structure and circuitry of the brain, with the intent of creating new strategies for early diagnosis. Dr. Kerchner also supervises the participation of patients in clinical trials for Alzheimer\u0092s disease."},{"lastName":"Marshel","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Bioengineering"}],"primaryAppointment":"Postdoctoral Research fellow, Bioengineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=34838&type=small&showNoImage","displayName":"James Marshel","firstName":"James","href":"http://med.stanford.edu/profiles/James_Marshel","researchInterest":""},{"lastName":"Uddin","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Psychiatry & Behavioral Science - Child and Adolescent Psychiatry"}],"primaryAppointment":"Instructor,Psychiatry & Behavioral Science - Child and Adolescent Psychiatry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10253&type=small&showNoImage","displayName":"Lucina Q. Uddin","firstName":"Lucina","href":"http://med.stanford.edu/profiles/Lucina_Uddin","researchInterest":"Cognitive, Developmental, and Social Neuroscience"},{"lastName":"Aoto","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurosciences Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Neurosciences Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=14864&type=small&showNoImage","displayName":"Jason Aoto","firstName":"Jason","href":"http://med.stanford.edu/profiles/Jason_Aoto","researchInterest":""},{"lastName":"Weiler","clinicalFocus":[],"appointments":[{"appointment":"Ph.D., Dean's Office"}],"primaryAppointment":"Ph.D., Dean's Office","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=19763&type=small&showNoImage","displayName":"Nicholas Weiler","firstName":"Nicholas","href":"http://med.stanford.edu/profiles/Nicholas_Weiler","researchInterest":"I am interested in the structure of neocortex and the relation of circuit structure to neural activity and circuit function. My work in the Smith lab focuses on the development of array tomography methods to characterize and quantify populations of cortical synapses based on the diverse proteomic \"fingerprints\" of molecules characteristically expressed by different synapse types. My primary goal is to quantify the distribution of distinct synapse classes within columns of barrel cortex"},{"lastName":"Longo","clinicalFocus":[{"focus":"Neurology"},{"focus":"Alzheimer's Disease"},{"focus":"Huntington Disease"}],"appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"}],"primaryAppointment":"Professor,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7249&type=small&showNoImage","displayName":"Frank M. Longo, M.D., Ph.D.","firstName":"Frank","href":"http://med.stanford.edu/profiles/Frank_Longo","researchInterest":"Clinical interests include Alzheimer\u0092s disease and Huntington\u0092s disease and the development of effective therapeutics for these disorders. Laboratory interests encompass the elucidation of signaling mechanisms relevant to neurodegenerative disorders and the development of novel small molecule approaches for the treatment of neurodegenerative and other neurological disorders."},{"lastName":"Madison","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Molecular & Cellular Physiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4321&type=small&showNoImage","displayName":"Daniel V. Madison","firstName":"Vernon","href":"http://med.stanford.edu/profiles/Vernon_Madison","researchInterest":"Our laboratory uses electrophysiological techniques to study the mechanisms of synaptic transmission and plasticity in the mammalian hippocampus. One of the main focuses in the lab is in the study of synaptic long-term potentiation (LTP). LTP is the persistent increase in synaptic strength that occurs after a period of heavy activity in a synaptic connection. It is the most widely studied and compelling model for mechanisms underlying memory formation in the mammalian central nervous system."},{"lastName":"Ding","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Neurology & Neurological Sciences"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=32293&type=small&showNoImage","displayName":"Jun Ding","firstName":"Jun","href":"http://med.stanford.edu/profiles/Jun_Ding","researchInterest":"Neural circuits of movement control in health and movement disorders"},{"lastName":"Ge","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=21246&type=small&showNoImage","displayName":"Xuecai Ge","firstName":"Xuecai","href":"http://med.stanford.edu/profiles/Xuecai_Ge","researchInterest":"I am interested in how the Hedgehog signaling transduction is regulated, and how the mis-regulation of Hedgehog pathway leads to human diseases such as Medulloblastoma."}]}