Vinicio de Jesus Perez MD

Clinical Focus

• Pulmonary Disease
• Pulmonary Hypertension

Administrative Appointments

• Assistant Professor of Medicine, Stanford University (2011 - present)
• Instructor, Stanford University (2006 - 2011)
• Postdoctoral Research Fellow-Rabinovitch Lab, Stanford University (2004 - 2008)

Honors and Awards

• Fellow, American College of Chest Physicians (2012)
• NIH Career Development Award (1 K08 HL105884-01), NIH (7/2012-7/2017)
• Wall Center Genomics Research Grant, Vera Moulton Wall Center for Pulmonary Vascular Research (2011-2012)
• Minority Travel Award, ATS (2010)
• Member-at-large, Cardiopulmonary, Critical Care, Perioperative & Resuscitation Council, American Heart Association (2010-)

Professional Education

Postdoctoral Advisees

Ke Yuan

Graduate & Fellowship Program Affiliations

• Biochemistry
• Developmental Biology
• Medicine
• Cell Biology

Community and International Work

• Latin American PH Society 
• Pulmonary Vascular Research Institute 
• North American Vascular Biology Society 
• American College of Chest Physicians 
• American Thoracic Society 

Internet Links

• de Jesus Perez Lab

Current Research Interests

My work is aimed at understanding the molecular mechanisms involved in the development and progression of pulmonary arterial hypertension (PAH). I am interested in understanding the role that the BMP and Wnt pathways play in regulating functions of pulmonary endothelial and smooth muscle cells both in health and disease.

Publications

• BMP promotes motility and represses growth of smooth muscle cells by activation of tandem Wnt pathways. Perez VA, Ali Z, Alastalo TP, Ikeno F, Sawada H, Lai YJ, Kleisli T, Spiekerkoetter E, Qu X, Rubinos LH, Ashley E, Amieva M, Dedhar S, Rabinovitch M. J Cell Biol. 2011; 192 (1): 171-88
• Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt-beta-catenin and Wnt-RhoA-Rac1 pathways. de Jesus Perez VA, Alastalo TP, Wu JC, Axelrod JD, Cooke JP, Amieva M, Rabinovitch M. J Cell Biol. 2009; 184 (1): 83-99
• Pulmonary hypertension associated with left heart disease: characteristics, emerging concepts, and treatment strategies. Haddad F, Kudelko K, Mercier O, Vrtovec B, Zamanian RT, de Jesus Perez V. Prog Cardiovasc Dis. 2011 Sep-Oct; 54 (2): 154-67
• Characteristics and outcome after hospitalization for acute right heart failure in patients with pulmonary arterial hypertension. Haddad F, Peterson T, Fuh E, Kudelko KT, de Jesus Perez V, Skhiri M, Vagelos R, Schnittger I, Denault AY, Rosenthal DN, Doyle RL, Zamanian RT. Circ Heart Fail. 2011; 4 (6): 692-9
• Chronic thromboembolic pulmonary hypertension. Perez VA, Zamanian RT. N Engl J Med. 2011; 364 (17): 1677; author reply 1678