Olivia Martinez

Administrative Appointments

• Director, Pre-Doctoral Program, Immunology IDP, Stanford University School of Medicine (2008 - present)

Honors and Awards

• Graduate Student Service Award, Stanford University School of Medicine (2011)
• Distinguished Service Award, American Association of Immunologists (2007)
• Faculty Mentor of the Year, Program in Immunology, Stanford University School of Medicine (2005)
• Fujisawa Basica Science Award, American Society of Transplantation (2004)

Professional Education

Postdoctoral Advisees

Shigetada Furukawa,  Olivia Hatton,  Amy Hill

Graduate & Fellowship Program Affiliations

• Immunology

Current Research Interests

There are two major areas of focus in the laboratory. First, we are interested in Epstein Barr Virus-mediated mechanisms of immune evasion with particular focus on resistance to cell death receptor pathways of apoptosis in EBV B cell lymphomas, the characterization of the human T cell response to EBV infected B cells and effects of immunosuppressive drugs on growth and survival of EBV B cell lymphomas. The second area of study addresses tolerance induction in solid organ transplantation. In particular we are examining the generation and characterization of regulatory T cells in allogeneic responses and the role of alternate co-stimulatory molecules in alloreactivity.

Publications

• Changes in natural killer cell subsets in pediatric liver transplant recipients. Pham B, Piard-Ruster K, Silva R, Gallo A, Esquivel CO, Martinez OM, Krams SM. Pediatr Transplant. 2012; 16 (2): 176-82
• Differential Expression of MicroRNAs During Allograft Rejection. Wei L, Wang M, Qu X, Mah A, Xiong X, Harris AG, Phillips LK, Martinez OM, Krams SM. Am J Transplant. 2012
• Emerging therapeutic strategies for Epstein-Barr virus+ post-transplant lymphoproliferative disorder. Hatton O, Martinez OM, Esquivel CO. Pediatr Transplant. 2012
• Distinct roles for the NK cell-activating receptors in mediating interactions with dendritic cells and tumor cells. Wai LE, Garcia JA, Martinez OM, Krams SM. J Immunol. 2011; 186 (1): 222-9
• Syk activation of phosphatidylinositol 3-kinase/Akt prevents HtrA2-dependent loss of X-linked inhibitor of apoptosis protein (XIAP) to promote survival of Epstein-Barr virus+ (EBV+) B cell lymphomas. Hatton O, Phillips LK, Vaysberg M, Hurwich J, Krams SM, Martinez OM. J Biol Chem. 2011; 286 (43): 37368-78