Joachim Hallmayer

Publication Details

• Linkage analysis between pericentrometric markers on chromosome 18 and bipolar disorder: a replication test.

  Maier W, Hallmayer J, Zill P, Bondy B, Lichtermann D, Ackenheil M, Minges J, Wildenauer D. Psychiatry Res. 1995; 59 (1-2): 7-15

  Replication was attempted of a recent report on linkage between bipolar affective disorder and pericentrometric loci on chromosome 18. Linkage to these markers was excluded in a sample of five extended multiplex families using lod-score and affected-pedigree-member methods. In one family, however, the lod score exceeded 1.0. Although the proposed susceptibility genes are unlikely to have a major impact on the occurrence of bipolar disorder, they might modify the genetic risk in a minority of familial cases.

  PubMedID: 8771215